دانلود مقالات ISI درباره Ikk + ترجمه فارسی

A novel protein kinase C target site in protein kinase D is phosphorylated in response to signals for cardiac hypertrophy

Keywords: CHK; checkpoint kinase; CRD; cysteine rich domain; DAG; diacylglycerol; ET-1; endothelin-1; GPCR; G-protein-coupled receptor; GSK-3β; glycogen synthase kinase-3β; HDAC; histone deacetylase; IKK; IκB kinase; ISO; isoproterenol; MARK; microtubule associa

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of inflammatory and antiviral signaling by A20

Keywords: A20; NF-κB; IKK; Ubiquitin; Antiviral signaling; Inflammation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Benznidazole treatment attenuates liver NF-κB activity and MAPK in a cecal ligation and puncture model of sepsis

Keywords: BZL; Benznidazole; CLP; cecal ligation and puncture; IKK; IκB kinase; Immunomodulation; Liver; NF-κB; Chagas' disease; Sepsis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Aqueous extract of Tribulus terrestris Linn induces cell growth arrest and apoptosis by down-regulating NF-κB signaling in liver cancer cells

Keywords: TT, Tribulus terrestris Linn; HCC, hepatocellular carcinoma; IκB, inhibitor of NF-κB; IKK, IκB kinase; cdks, cyclin-dependent kinasesTribulus terrestris L.; Liver cancer cell; NF-κB; IκBα; IKK; Apoptosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Novel tricyclic inhibitors of IKK2: Discovery and SAR leading to the identification of 2-methoxy-N-((6-(1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl)pyridin-2-yl)methyl)acetamide (BMS-066)

Keywords: IKK; IKK2; IKKβ; NF-κB; BMS-066

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Inducible astrocytic glucose transporter-3 contributes to the enhanced storage of intracellular glycogen during reperfusion after ischemia

Keywords: GLUT; glucose transporter; HE; Hoechst 33342; IKK; inhibitor of κB kinase; NF-κB; nuclear factor-κB; OGD; oxygen glucose deprivation; PC; preconditioning; Astrocytes; GLUT3; GLUT1; Ischemic stress; Glycogen;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Cyclic AMP-mediated immune regulation - Overview of mechanisms of action in T cells

Keywords: AC; Adenylyl cyclase; AKAP; A-kinase anchoring protein; AKAP-KL; AKAP-kidney lung; AKB; A-kinase binding domain; AP-1; Activator protein 1; ATF; Activation transcription factor; C; Catalytic (subunit of PKA); CBP; CREB-binding protein; CNG; Cyclic nucleot

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

TCM grammar systems: An approach to aid the interpretation of the molecular interactions in Chinese herbal medicine

Keywords: TCM; Traditional Chinese medicines; HED; Herba Ephedrae Decoction; EGS; entity grammar systems; ASP; answer set programming; IL1; Interleukin 1; IL1R1; Interleukin 1 receptor 1; IRAK1; Interleukin-1 receptor-associated kinase; TNFR; Tumor Necrosis Factor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways

Keywords: Psoralidin; LPS; Syk; PI3K; IKK; NF-κB; iNOS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Ethnopharmacological communicationAnti-inflammatory activity of Sorbus commixta water extract and its molecular inhibitory mechanism

Keywords: Sc-WE; water extract of Sorbus commixta; LPS; lipopolysaccharide; NO; nitric oxide; PG; prostaglandin; iNOS; inducible NO synthase; COX; cyclooxy-genase; TNF; tumor necrosis factor; IL; interleukin; IKK; IκBα kinase; Akt; protein kinase B; PDK; phosphoi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

How vaccinia virus has evolved to subvert the host immune response

Keywords: Bcl-2; B-cell lymphoma-2; CPXV; Cowpox virus; dsDNA; double-stranded DNA; ECTV; ectromelia virus; GAGs; glycosaminoglycans; GPCRs; G-protein coupled receptors; IFN; interferon; IG; immunoglobulin; PDB; protein data bank; RPXV; rabbitpox virus; r.m.s.d.; r

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

CCL27 expression is regulated by both p38 MAPK and IKKβ signalling pathways

Keywords: MAPK; mitogen-activated protein kinase; MSK; mitogen- and stress-activated protein kinase; Mnk; mitogen-activated protein kinase (MAPK)-interacting kinase; IκB; inhibitory κB; IKK; IκB kinase; NF-κB; nuclear factor-κB; NHEK; normal human epidermal ke

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The role of 20-HETE in androgen-mediated hypertension

Keywords: Androgen; DHT; Hypertension; 20-HETE; CYP4A/F; ACE; IKK; Endothelial dysfunction; Vascular reactivity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues

Keywords: AP-1; activator protein-1; BAL; bronchoalveolar lavage; bw; body weight; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; ICAM-1; intercellular adhesion molecule-1; IKK; IκB kinase; IL; interleukin; LPS; lipopolysaccharide; MCP-1; monocyte chemoattractan

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Oxidative stress, insulin signaling, and diabetes

Keywords: AGE; advanced glycated end product; CAP; c-Cbl-associated protein; DAG; diacylglycerol; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinase; ETC; electron transport chain; GH; growth hormone; GLUT4; glucose transporter type

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay

Keywords: Adenosine; A2A; JNK; IKK; CXCR3; Microglia; Neurodegeneration; Neuroprotection; Biolistics; Brain slice; Drug discovery; Inflammation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes

Keywords: AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK; AMP-activated protein kinase; BCH; 2-aminobicyclo[2.2.1]heptan-2-carboxylic acid; CPT-1; carnitine palmitoyl transferase-1; FFA; free fatty acid; FAO; fatty acid oxidation; GLUT4; glucose

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway

Keywords: ADAM; a disintegrin and metalloproteinase; BSA; bovine serum albumin; CHO-TNFΔ[1-12]; Chinese Hamster Ovary cells transfected with TNFΔ[1-12]; DKO MEF; mouse embryonic fibroblasts from TNFR1-/-/TNFR2-/- mice; EEA1; early endosomal antigen 1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans

Keywords: Pa-EE; ethanol extract of Phaseolus angularis; LPS; lipopolysaccharide; NO; nitric oxide; PG; prostaglandin; iNOS; inducible NO synthase; COX; cyclooxy-genase; IL; interleukin; IKK; I (B) kinase; Akt; protein kinase B; PDK; phosphoinositide-dependent kina

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Acute administration of 3,4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver

Keywords: AA; ascorbic acid; α - Me Da; α - methyldopamine; A-SMase; acidic sphingomyelinase; ATP; adenosintriphosfato; Bax/Bak; BCL2-associated X protein/BCL2-antagonist/killer 1; Bcl-2; B cell lymphoma gene-2; BHT; butylhydroxytoluene; BID; BH3-interacting

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

PKCθ activation in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors is needed for stimulation of numerous important cellular signaling cascades

Keywords: CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; GI; gastrointestinal; CCK-JMV; CCK-JMV-180; IP; immunoprecipitation; Co-IP; co-immunoprecipitation; PKD; protein kinase D; GPCR; G protein-coupled receptor; PYK2

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus

Keywords: NEMO; immunodeficiency; Toll-like receptor 3; herpes simplex encephalitis; CNS; Central nervous system; EDA-ID; Anhidrotic ectodermal dysplasia with immunodeficiency; HSE; Herpes simplex encephalitis; HSV-1; Herpes simplex virus-1; IKK; Inhibitor of nucle

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

IκB kinase-driven nuclear factor-κB activation in patients with asthma and chronic obstructive pulmonary disease

Keywords: Asthma; chronic obstructive pulmonary disease; inflammation; IκB kinase/nuclear factor κB pathway; ATS; American Thoracic Society; COPD; Chronic obstructive pulmonary disease; CSE; Cigarette smoke extract; FP; Fluticasone propionate; FVC; Forced vital c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Signal-transduction networks and the regulation of muscle protein degradation

Keywords: 15(S)-HETE; 15(S)-hydroxyeicosatetraenoic acid; ACh; acetylcholine; Akt; protein kinase B; CNTF; ciliary neurotrophic factor; EGF; epidermal growth factor; FGF; fibroblast growth factor; FOXO; forkhead transcription factor; Grb2; growth factor receptor bo

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Adaptive response to oxidative stress: Bacteria, fungi, plants and animals

Keywords: AHP1; alkylhydroperoxide reductase; AHR; aryl hydrocarbon receptor; ARE; antioxidant response element; 2CPA; 2-Cys peroxiredoxin-A; CRD; cysteine rich domain; Cul3; Cullin 3; DPH; diphenylhexatriene; EpRE; electrophile response element; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Old and new generation lipid mediators in acute inflammation and resolution

Keywords: 5-HT; 5-hydroxytryptamine; HETEs; hydroxyeicosatetraenoic acids; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5(S)-HPETE; hydroperoxyeicosatetranoic acid; 15R-HETE; 15-R-hydroxyeicosatetraenoic acid; 17R-HDHA; 17R-hydroxydocosahexaenoic acid; AA; arachidoni

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Myeloid, but Not Pancreatic, RelA/p65 Is Required for Fibrosis in a Mouse Model of Chronic Pancreatitis

Keywords: Immune Regulation; Genetics; Microarray Analysis; Expression Profile; BMDM; bone marrow-derived macrophages; CP; chronic pancreatitis; eCP; experimental chronic pancreatitis; ECM; extracellular matrix; EMSA; electrophoretic mobility shift assay; IκB; inh

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2011 سفارش ترجمه

Involvement of phosphatidylcholine-phospholipase C and protein kinase C in peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages

Keywords: COX-2; cyclooxygenase-2; DMEM; Dulbecco's modified Eagle's medium; IKK; IκB kinase; NF-κB; nuclear factor-κB; NIK; NF-κB-inducing kinase; PGN; peptidoglycan; PC-PLC; phosphatidylcholine-phospholipase C; PI-PLC; phosphatidylinositol-PLC; PKC; p

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Clinical Application of Basic ScienceNF-κB signalling: Embracing complexity to achieve translation

Keywords: NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; IKK; IkappaB kinase; CBP; CREB binding protein; RANTES; Regulated upon Activation, Normal T cell Expressed and Secreted; NF-κB; IKK; NEMO; RelA; RelB; c-Rel; p50; p52; Phosphorylatio

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

I-κBα depletion by transglutaminase 2 and μ-calpain occurs in parallel with the ubiquitin-proteasome pathway

Keywords: TGase; transglutaminase; IKK; I-κBα kinase; NF-κB; nuclear factor-κB; I-κBα; inhibitory subunit of NF-κB; CTM; cystamine; Transglutaminase 2; I-κBα; NF-κB; μ-Calpain; Proteasome;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Cyclic AMP Inhibits IL-1β Plus IFNγ-Induced NF-κB Translocation in Hepatocytes by a PKA Independent Mechanism

Keywords: cyclic AMP; IKK; NF-κB; hepatocyte; PKA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibition of IkB kinase and NF-κB by a novel synthetic compound SK 2009

Keywords: Novel chemical entities; TNF; NF-κB; IKK; KBM-5 cells; SimplactonesTNF, tumor necrosis factor; NF-κB, nuclear factor-κB; IKK, IκB kinase; 2,2-DMP, 2,2-dimethoxy propane; NaBH4, sodium borohydride; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Vitamin K suppresses the lipopolysaccharide-induced expression of inflammatory cytokines in cultured macrophage-like cells via the inhibition of the activation of nuclear factor κB through the repression of IKKα/β phosphorylation

Keywords: Anti-inflammation; IKK; Macrophage; Nuclear factor κB; Vitamin K

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IκB kinase-2 (IKK-2) target safety and efficacy

Keywords: NF-κB; IκB; IKK; oral; steady state; dose-response; efficacy; pharmacokinetic; in vivo; safety; NOAEL;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase

Keywords: Indoleamine 2, 3-dioxygenase; kynurenine; inhaled corticosteroid; simvastatin; asthma; GITR; Glucocorticoid-inducible TNF receptor; GITRL; Glucocorticoid-inducible TNF receptor ligand; ICS; Inhaled corticosteroid; IDO; Indoleamine 2, 3-dioxygenase; IKK; I

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Prolyl Hydroxylase-3 Is Down-regulated in Colorectal Cancer Cells and Inhibits IKKβ Independent of Hydroxylase Activity

Keywords: DMOG; dimethyloxaloylglycine; FIH; factor inhibiting HIF; GST; glutathione S-transferase; HIF; hypoxia inducible factor; IκB; inhibitor of nuclear factor-κB; IKK; IκB kinase; NF; nuclear factor; PHD; prolyl hydroxylase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

A schizont-derived protein, TpSCOP, is involved in the activation of NF-κB in Theileria parva-infected lymphocytes

Keywords: TpSCOP; T. parvaschizont-derived cytoskeleton-binding protein; NF-κB; nuclear factor-kappa B; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; IKK; multisubunit IκB kinase; ToMRP; micronem

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour

Keywords: Amniotic fluid; Chorioamnionitis; IKK; MAPK; Preterm delivery; Th17

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Gα16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS)

Keywords: ERK; extracellular signal-regulated kinase; GPCRs; G protein-coupled receptors; HEK 293; human embryonic kidney 293; IKK; IκB kinase; NFκB; nuclear factor κB; PLCβ; phospholipase Cβ; STAT3; signal transducer and activator of transcription 3; TPR1; te

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Immune deficiency caused by impaired expression of nuclear factor-κB essential modifier (NEMO) because of a mutation in the 5′ untranslated region of the NEMO gene

Keywords: NEMO; immune deficiency; recurrent infections; 5′ untranslated region mutation; EDID; Ectodermal dysplasia associated with immune deficiency; IκB; Inhibitor of nuclear factor κB; IKK; Inhibitor of nuclear factor-κB kinase complex; NEMO; Nuclear fact

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

NF-κB inducing kinase: A key regulator in the immune system and in cancer

Keywords: NF-κB inducing kinase (NIK); NF-κB; IKK; Canonical pathway; Non-canonical pathway

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Malt1 and cIAP2-Malt1 as effectors of NF-κB activation: Kissing cousins or distant relatives?

Keywords: MALT; mucosa associated lymphoid tissue; cIAP2; cellular inhibitor of apoptosis 2; IKK complex; inhibitor of κB kinase; TCR; T cell receptor; BCR; B cell receptor; Bcl10; B cell lymphoma 10; CARD; caspase associated recruitment domain; BIR; baculovirus I

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

A Multitude of Kinases-Which are the Best Targets in Treating Rheumatoid Arthritis?

Keywords: MAPKs; Tyrosine kinases; IKK; Jak; Syk; Small-molecule inhibitors;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Inflammation and Colon Cancer

Keywords: Colon Cancer; Inflammation; Immunity; Cytokines; AOM; azoxymethane; APC; adenomatous polyposis coli; CAC; colitis-associated cancer; COX2; cyclooxygenase 2; CRC; colorectal cancer; DC; dendritic cells; DSS; dextran sodium sulfate; EGF; epidermal growth fa

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IκB kinase

Keywords: IKK; TNF; SAR; LPS

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Oleic acid reduces lipopolysaccharide-induced expression of iNOS and COX-2 in BV2 murine microglial cells: Possible involvement of reactive oxygen species, p38 MAPK, and IKK/NF-κB signaling pathways

Keywords: LPS; BV2 microglia; iNOS; COX-2; NF-κB; IKK; ROS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Cationic lipids activate cellular cascades. Which receptors are involved?

Keywords: AP-1; activator protein 1; CD 14/80/86; cluster of differentiation 14/80/86; diC14-amidine; N-t-butyl-N′-tetradecyl-3-tetradecylaminopropionamidine; DAG; diacylglycerol; DMPC; dimyristoyl-phosphatidylcholine; DMPG; dimyristoyl-phosphatidylglycerol; DMKD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Glucosamine is an effective chemo-sensitizer via transglutaminase 2 inhibition

Keywords: Transglutaminase 2; Drug resistance; Glucosamine; NF-κB; I-κBα; IKK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

C/EBPβ enhances NF-κB-associated signalling by reducing the level of IκB-α

Keywords: NF-κB; nuclear factor-κB; C/EBP; CCAAT/enhancer-binding protein; IκB; inhibitor of NF-κB; TNF; tumor necrosis factor; LPS; bacterial lipopolysaccharide; IKK; IκB kinase; C/EBPβwt; C/EBPβ wild type cells; C/EBPβko; C/EBPβ knock out cells; FCS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

IKKβ inhibitors identification part I: Homology model assisted structure based virtual screening

Keywords: IKK; IKKβ; Inhibitor kappa B kinase; Homology modeling; Virtual screening; Docking; Flex-X; Pharmacophore constraints; Enrichment

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه