دانلود مقالات ISI درباره Ikk + ترجمه فارسی

Interleukin-10 activates Toll-like receptor 4 and requires MyD88 for cardiomyocyte survival

Keywords: Anti-IL-10R; antibody to interleukin-10 receptor; CD14; cluster differentiation 14; Ikk; antibody to interleukin-10 receptor; IkkB; inhibitory kinase B; IL-1β; interleukin-1β; IL-10; interleukin-10; IRF3; interferon regulatory factor 3; ISRE; interferon

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling

Keywords: AGE; advanced glycation end product; AOPP; advanced oxidation protein product; AP-1; activator protein-1; CD36; cluster determinant 36; CRP; C-reactive protein; dn; dominant negative; CuZnSOD; copper/zinc superoxide dismutase; DPI; diphenylene iodonium; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes

Keywords: AICAR; 5-amino-4-imidazole-carboxamideriboside; ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; CRP; C-reactive protein; HP; haptoglobin; IKK; IkappaB kinase; IL-6; Interleukin-6; IL6Rα; IL-6 receptor subun

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication

Keywords: 5′ ppp; 5′ triphosphate; AIM2; Absent In Melanoma 2; ARE; AU-rich element; CARD; Caspase Activation and Recruitment Domains; CDN; cyclic dinucleotide; cGAMP; cyclic-GMP-AMP; cGAS; cGAMP Synthase; CRM1; Chromosome Maintenance Region 1; CstF; Cleavage S

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response

Keywords: NF-κB; nuclear factor-κB; UV; ultraviolet; IκB; inhibitor of NF-κB; IKK; IκB kinase; NEMO; NF-κB essential modulator; TNFR; tumor necrosis factor receptor; IL-1R; interleukin-1 receptor; NIK; NF-κB inducing kinase; LPS; lipopolysaccharide; PKD; pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction

Keywords: Act1; activator of NF-κB; AOPPs; advanced oxidation protein products; AGE; advanced glycation end product; AP-1; activator protein-1; C/EBP; CCAAT/enhancer-binding protein; CIKS; connection to IKK and SAPK/JNK; DCFH-DA; 2′,7′-dichlorofluorescin-diace

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

Keywords: 6-OHDA; 6-Hydroxydopamine; AAV; adeno-associated virus; AD; Alzheimer's disease; ANOVA; analysis of variance; AP; anteroposterior; BDNF; brain-derived neurotrophic factor; CD200; cluster of differentiation 200; DLB; dementia with Lewy bodies; DV; dorsoven

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation

Keywords: Asthma; viral respiratory tract infections; glucocorticoids; transcription factors; kinases; EC50; Median effective concentration; Emax; Maximal effective concentration; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; GR; Glucocorticoid receptor; GRE; Gl

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Minimal NF-κB activity in neurons

Keywords: AP5; 2-amino-5-phosphonopentanoate; BDNF; brain-derived neurotrophic factor; BRN; mixed brain cells; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CxN; cortical neurons; DMEM; Dulbecco's modified Eagle's medium; EDTA; ethylenediaminetetraacetic acid; EG

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91phox to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock

Keywords: 20-HEDE; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid; AA; arachidonic acid; 20-HETE; 20-hydroxyeicosatetraenoic acid; 5,14-HEDGE; N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine; 1,3-PBIT; phenylene-1,3-bis(ethane-2-isothiourea) dihydrobromide; cDNA; compleme

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2013 سفارش ترجمه

A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways

Keywords: ARE; antioxidant response element; COX-2; cyclooxygenase-2; ECM; extracellular matrix; HO-1; heme oxygenase-1; iNOS; inducible nitric oxide synthase; IκBα; inhibitor of kappaBα; IKK; IκB kinase; MMP; matrix metalloproteinase; Keap1; Kelch-like ECH-ass

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2013 سفارش ترجمه

Inflammation, Autophagy, and Obesity: Common Features in the Pathogenesis of Pancreatitis and Pancreatic Cancer

Keywords: Pancreatic Acinar Cell; Cytokines; Neutrophil; Pancreatic Ductal Adenocarcinoma; K-Ras; AMP; adenosine monophosphate; AP; acute pancreatitis; ATG; autophagy related; Cat; cathepsin; CP; chronic pancreatitis; DAMP; damage/danger-associated molecular patter

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Human T Cell Leukemia Virus Type I Tax-Induced IκB-ζ Modulates Tax-Dependent and Tax-Independent Gene Expression in T Cells

Keywords: Abs; antibodies; AP-1; activator protein 1; ATL; adult T cell leukemia; Bcl3; B cell CLL/lymphoma 3; CBB; Coomassie brilliant blue; CREB; cyclic adenosine 3′,5′-monophosphate response element-binding protein; EGFP; enhanced green fluorescent protein;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Transforming Growth Factor-β Signaling in Hepatocytes Promotes Hepatic Fibrosis and Carcinogenesis in Mice With Hepatocyte-Specific Deletion of TAK1

Keywords: Liver Cancer; Mouse Model; Signal Transduction; Oncogene; ALT; alanine aminotransferase; CTGF; connective tissue growth factor; DEN; n-nitrosodiethylamine; GFP; green fluorescent protein; HCC; hepatocellular carcinoma; IKK; IκB kinase; IL; interleukin; J

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Cordycepin suppresses TNF-α-induced NF-κB activation by reducing p65 transcriptional activity, inhibiting IκBα phosphorylation, and blocking IKKγ ubiquitination

Keywords: Cordycepin; NF-κB; IκB; IKK;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Wnt5a activates THP-1 monocytic cells via a β-catenin-independent pathway involving JNK and NF-κB activation

Keywords: FBS; fetal bovine serum; FHC; ferritin heave chain; HAECs; human aortic endothelial cells; IFN; interferon; IKK; IkB kinase; JNK; c-Jun N-terminus kinase; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; MKK; mitogen-activated-protein kina

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Role of CSN5/JAB1 in Wnt/β-catenin activation in colorectal cancer cells

Keywords: CSN5; COP9 signalosome; Protein degradation; Cullin-RING-ubiquitin ligase; MIF; p53; APC; adenomatous polyposis coli; CDK; cyclin-dependent kinase; CHX; cycloheximide; COP; constitutive photomorphogenesis; CSN; COP9 signalosome; CRC; colorectal cancer; CR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways

Keywords: AKT/PKB; RAC-alpha serine/threonine-protein kinase; ERK1/2; extracellular signal-regulated kinase 1/2; GRB2; growth factor receptor-bound protein 2; GA; gallic acid; JNK; c-Jun N-terminal kinase; IKK; IκB kinase; MAPK; mitogen-activated protein kinase; M

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

S-nitrosylation of surfactant protein D as a modulator of pulmonary inflammation

Keywords: TLR; Toll-like receptor; TIR; Toll/IL-1 receptor domain; LPS; lipopolyssacharides; LBP; LPS-binding protein; MD-2; myeloid differentiation factor 2; MyD88; myeloid differentiation protein 88; IRAK; IL-1 receptor associated kinase; TRAF6; TNF receptor asso

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Methanol extract of Osbeckia stellata suppresses lipopolysaccharide- and HCl/ethanol-induced inflammatory responses by inhibiting Src/Syk and IRAK1

Keywords: Os-ME; methanol extract of Osbeckia stellata; PGE2; prostaglandin E2; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; TNF-α; tumor necrosis factor-alpha; ERK; extracellular signal-related kinase; TLR; toll-like receptor; MAPK; mitogen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A novel role for the Rho-associated kinase, ROCK, in IL-1-stimulated intestinal epithelial cell responses

Keywords: FN; fibronectin; GAPD; glyceraldehyde-3-phosphate dehydrogenase; IBD; inflammatory bowel disease; IEC; intestinal epithelial cell; IKK; IκB kinase; IL; interleukin; ITS; insulin, transferrin, selenium; RI; Y27632 ROCK inhibitor; IL-1; Intestinal epitheli

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

IKK-β mediates chemoresistance by sequestering FOXO3; A critical factor for cell survival and death

Keywords: FOXO3; IKK; Chemoresistance; Cell death; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Prolongation of carrageenan-induced inflammation in human colonic epithelial cells by activation of an NFκB‐BCL10 loop

Keywords: BCL10; B-cell leukemia/lymphoma 10; CAPE; caffeic phenethyl ester; CARMA; caspase recruitment domain membrane-associated guanylate kinase; CBM; CARMA-BCL10-MALT complex; CGN; carrageenan; ChIP; chromatic immunoprecipitation; DSS; dextran sulfate sodium; H

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Populus balsamifera L. (Salicaceae) mitigates the development of obesity and improves insulin sensitivity in a diet-induced obese mouse model

Keywords: ACC; acetyl-CoA carboxylase; AMPk; adenosine monophosphate-activated protein kinase; BAT; brown adipose tissue; C/EBP; CCAAT-enhancer binding proteins; CPT-1; carnitine palmitoyltransferase-I; DIO; diet-induce obese; ERK; extracellular signal-regulated ki

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitory effects of aurentiacin from Syzygium samarangense on lipopolysaccharide-induced inflammatory response in mouse macrophages

Keywords: LPS; lipopolysaccharide; NO; nitric oxide; iNOS; inducible nitric oxide synthase; TNF-α; tumor necrosis factor-α; IL-6; interleukin-6; EMSA; electrophoretic mobility shift assay; NF-κB; nuclear factor-κB; ChIP; chromatin immunoprecipitation; IKK; I-κ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Caffeic acid phenethyl ester reduces the activation of the nuclear factor κB pathway by high-fat diet-induced obesity in mice

Keywords: CAPE; caffeic acid phenethyl ester; HFD; high-fat diet; AUGC; area under glucose curve; OGTT; Oral glucose tolerance test; IRS; insulin receptor substrate; JNK; c-jun N-terminal kinase; IKKβ; inhibitor of nuclear factor kappa B kinase beta subunit; IκB;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleLiver specific deletion of CYLDexon7/8 induces severe biliary damage, fibrosis and increases hepatocarcinogenesis in mice

Keywords: NF-κB; Nuclear factor kappa B; IKK; inhibitor of NF-κB kinase complex; NEMO/IKKγ; NF-κB essential modulator; IκB; inhibitor of NF-κB; BCL-3; B-cell lymphoma-leukemia-3; RIP; Receptor interacting protein; PMH; primary murine hepatocytes; PMC; primary

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dangkwisoo-san, an herbal medicinal formula, ameliorates acute lung inflammation via activation of Nrf2 and suppression of NF-κB

Keywords: Nrf2; nuclear factor (NF)-erythroid (E) 2 related factor 2; GCL; Cglutamate-cysteine ligase catalytic subunit; NQO1; NAD(P)H:quinine oxidoreductase-1; HO-1; heme oxygenase-1; IKK; inhibitory κB kinase; Acute lung inflammation; Anti-inflammation; Nrf2; NF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Human telomerase represses ROS-dependent cellular responses to Tumor Necrosis Factor-α without affecting NF-κB activation

Keywords: hTERT; human telomerase reverse transcriptase catalytic subunit; hTR; human telomerase RNA component; ROS; reactive oxygen species; TNF-α; tumor necrosis factor-α; NAC; N-acetyl-L-cysteine; CHX; cycloheximide; ERK1/2; extracellular signal-regulated kina

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease

Keywords: BMI; body mass index; FA; fatty acid; FC; fold-change; FFA; free fatty acid; GO; gene ontology; GSA; gene set analysis; HbA1c; glycated hemoglobin; IGA; individual gene analysis; IKK; I-kappa-B kinase; IL; interleukin; IRS; insulin receptor substrate; JNK

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Double-edged sword effect of biochanin to inhibit nuclear factor kappaB: Suppression of serine/threonine and tyrosine kinases

Keywords: AP-1; activator protein 1; C3-toxin; Clostridium botulinum C3 transferase; CE; cytoplasmic extracts; Cox2; cyclooxygenase 2; ICAM; intercellular adhesion molecule; NF-κB; nuclear transcription factor kappaB; IL; interleukin; IκB; inhibitory subunit of N

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Beta-d-glucoside protects against advanced glycation end products (AGEs)-mediated diabetic responses by suppressing ERK and inducing PPAR gamma DNA binding

Keywords: AGEs; advanced glycation end products; DAPI; 4′-6-diamidino-2-phenylindole; HSA; human serum albumin; IκBα; inhibitory subunit of NF-κB; IKK; IκBα kinase; JNK; c-Jun N-terminal kinase; IκBα-DN; dominant negative of IκBα; MBP; myelin basic prote

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular mechanism of the anti-inflammatory activity of a natural diarylnonanoid, malabaricone C

Keywords: AP-1; activator protein-1; COX-2; cyclooxygenase-2; IKK; IκB kinase; IRAK-4; IL-1 receptor-associated kinase-4; iNOS; inducible nitric oxide synthase; IL; interleukin; LPS; lipopolysaccharide; mal C; malabaricone C; MAP; mitogen-activated protein; MAPK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy

Keywords: Act1; activator of NF-κB; ACM; adult cardiomyocytes; ANF; atrial natriuretic factor; AP-1; activator protein-1; AT1; angiotensin II type 1 receptor; ATRAP; AT1-receptor-associated protein; ARAP1; type 1 Ang II-receptor-associated protein 1; C/EBP; CCAAT/

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Reduced Expression of UGT1A1 in Intestines of Humanized UGT1 Mice via Inactivation of NF-κB Leads to Hyperbilirubinemia

Keywords: Nursing; Mouse Model; Neonatal Jaundice; Gene Regulation; AhR; aryl hydrocarbon receptor; BIND; bilirubin-induced neurological dysfunction; CAR; constitutive androstane receptor; Cyp; cytochrome P450; GI; gastrointestinal; IKK; IκB kinase; LPS; lipopolys

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

TiSH - a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC

Keywords: ACN; Acetonitrile; ATP; Adenosine triphosphate; DHB; 2,5-Dihydroxy benzoic acid; dsRNA; Double stranded RNA; DTT; Dithiothreitol; FDR; False discovery rate; FWHM; Full width at half maximum; HCD; Higher-energy collision dissociation; HILIC; Hydrophilic in

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

IκB Kinases Modulate the Activity of the Androgen Receptor in Prostate Carcinoma Cell Lines

Keywords: AR; androgen receptor; CRPCa; castration-resistant prostate cancer; IKK; IκB kinase; PCa; prostate cancer;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

RNA therapeutics targeting osteoclast-mediated excessive bone resorption

Keywords: 3BP2; c-Abl SH3 domain-binding protein-2; ADAM; a disintegrin and metalloproteinases; Ago; Argonaute; AP-1; activator protein-1; Ckb; brain-type creatine kinase; CNV; choroidal neovascularization; CPA; cation-proton antiporter; CPC; calcium phosphate bone

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Using mice to unveil the genetics of cancer resistance

Keywords: AC; adenocarcinoma; AOM; azoxymethane; APC; antigen-presenting cells; BH; BCL2 homology; CCl4; carbon tetrachloride; cM; centimorgan; COX; cyclo-oxygenase; CTLA-4; cytotoxic T-lymphocyte antigen 4; DC; dendritic cells; DEN; diethylnitrosamine; DMBA; 7,12-

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

NF-κB Essential Modifier Is Required for Hepatocyte Proliferation and the Oval Cell Reaction After Partial Hepatectomy in Mice

Keywords: PEITC; Liver Disease; Mouse Model; Tissue Regeneration; BHA; butylated hydroxyanisole; BrdU; 5-bromo-2′-deoxyuridine; DAPI; 4′,6-diamidino-2-phenylindole; DDC; 3,5-diethoxycarbonyl-1,4-dihydro-collidin; DSB; double-strand break; FHC; ferritin heavy ch

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2012 سفارش ترجمه

Flotillin-1 Promotes Tumor Necrosis Factor-α Receptor Signaling and Activation of NF-κB in Esophageal Squamous Cell Carcinoma Cells

Keywords: IκB Kinase Activation; Ubiquitination; Phosphorylation; Mouse Model; ESCC; esophageal squamous cell carcinoma; FLOT1; flotillin-1; HUVEC; human umbilical vein endothelial cells; IHC; immunohistochemistry; IκB; inhibitor of nuclear factor-κB; IκBα-mu;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2012 سفارش ترجمه

DEHP: Genotoxicity and potential carcinogenic mechanisms-A review

Keywords: ADME; absorption, distribution, metabolism and elimination; CAR; constitutive androstane receptor; CERHR; NTP Center for the Evaluation of Risks to Human Reproduction; CHO; Chinese hamster ovary; CYP; cytochrome p450; CpG; cytosine guanine dinucleotide; D

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2012 سفارش ترجمه

Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: Synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis

Keywords: IKK; IKK2; IKKβ; NF-κB;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

3,5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β

Keywords: Kinase; IKK-β; IKK; Indolecarboxamide

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

FcεRI-induced mast cell cytokine production critically involves an aspartic acid residue (D234) in the C-terminal intracellular domain of the FcεRIβ chain

Keywords: ITAM; immunoreceptor tyrosine-based activation motif; CD; circular dichroism; BMMCs; bone marrow-derived mast cells; TNP; trinitrophenyl; GST; glutathione S-transferase; TLR; toll-like receptor; TIRAP; toll/IL-1R-containing adaptor protein; IKK; IκB kina

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: Improvement of potency in vitro and in vivo

Keywords: IKK; NF-κB; TNFα; Inhibitor; Interaction model

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway

Keywords: COX-2; cyclooxygenase-2; DMSO; dimethyl sulfoxide; D-GlaN; D-galactosamine; IL-1; interleukin-1; IκB-α; inhibitory kappa B-α; IKK; IκB kinase; iNOS; inducible nitric oxide synthase; IRAK; interleukin-1 receptor-associated kinase; LPS; lipopolysacchari

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular cloning of IKKβ from the mandarin fish Siniperca chuatsi and its up-regulation in cells by ISKNV infection

Keywords: IKK; ISKNV; NF-κB; Mandarin fish; Infection

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: Exploration of effective compounds in arthritis models

Keywords: Inhibitor; IKK; TNF; Imidazo[1,2-b]pyridazine; Collagen-induced arthritis; Pharmacokinetic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه