Interleukin-1 receptor null mutant mice show decreased anxiety-like behavior and enhanced fear memory
Keywords: IL-1β; Anxiety; Fear; IL-1RI KO mice;
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The inhibitory effect of 15-R-LXA4 on experimental endometriosis
Keywords: Endometriosis; Murine model; 15-R-LXA4; IL-1β; TNF-α;
Neonatal lipopolysaccharide exposure attenuates the homotypic stress-induced suppression of LH secretion in adulthood in male rat
Keywords: Stress; LH; Testosterone; IL-1β; TNF-α;
Dichroa febrifuga Lour. inhibits the production of IL-1β and IL-6 through blocking NF-κB, MAPK and Akt activation in macrophages
Keywords: Dichroa febrifuga; IL-1β; IL-6; NF-κB; Akt; Mitogen-activated protein kinase (MAPK);
Effect of oral erythromycin therapy in patients with aseptic loosening of joint prostheses
Keywords: TNF α; tumor necrosis factor alpha; IL-1β; interleukin 1 beta; TRAP; tartrate-resistant acid phosphatase; AL; aseptic loosening; TJR; total joint replacement; EM; erythromycin; RANKL; nuclear factor kappa B ligand; OPG; osteoprotegerin.; Erythromycin; W
Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice
Keywords: bone marrow transplantation; green fluorescent protein; microglia; hematogenous macrophages; DAPI; 4â²,6-diamidino-2-phenylindole; GFP; green fluorescent protein; IL-1β; interleukin-1β; MCA; middle cerebral artery; MCP-1; monocyte chemoattractant prote
Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways
Keywords: SOD; superoxide dismutase; MnP, MnIIITE-2PyP5+; Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin (AEOL-10113); MnTnHex-2-PyP5+; Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin; FeTM-4-PyP5+; Fe(III) meso-tetrakis(N-methylpyridinium-4-yl)por
Expression and regulation of antiviral protein APOBEC3G in human neuronal cells
Keywords: APOBEC3G; apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G; BDNF; brain-derived neurotrophic factor; BMVECs; brain microvascular endothelial cells; CCL3; CC chemokine ligand 3; CCL4; CC chemokine ligand 4; CCL5; CC chemokine ligand 5; C
Combinatory responses of proinflamamtory cytokines on nitric oxide-mediated function in mouse calvarial osteoblasts
Keywords: IL-1β; TNF-α; INF-γ; TGF-β; NOS; Osteoblast; Cytokine;
The absence of a functional peroxisome proliferator-activated receptor-alpha gene in mice enhances motor sensitizing effects of morphine, but not cocaine
Keywords: morphine; cocaine; sensitization; PPAR; neuroinflammation; WY14643; COX-2; cyclooxigenase-2; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; HPA; hypothalamic-pituitary-adrenal; IL-12; interleukin-12; IL-1β; interleukin-1β; IL-2; interl
Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways
Keywords: ADAM; a disintegrin and metalloproteinase; α-LA; α-lipoic acid; APC; activated protein C; APMA; 4-aminophenylmercuric acetate; BSA; bovine serum albumin; CV; crystal violet; DHLA; dihydrolipoic acid; DMSO; dimethyl sulfoxide; DPI; diphenylene iodonium;
The NALP1 inflammasome controls cytokine production and nociception in a rat fracture model of complex regional pain syndrome
Keywords: SP; substance P; NK1R; substance P NK1 receptor; IL-1β; interleukin-1β; IL-1βR; interleukin-1β receptor; IL-18; interleukin 18; IL-18R; interleukin 18 receptor; NALP; Nacht leucine-rich repeat and pyrin domain containing protein; ASC; caspase-activati
Inhibition of inflammatory mediators by polyphenolic plant extracts in human intestinal Caco-2 cells
Keywords: AP-1; activator protein-1; COX-2; cyclooxygenase-2; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; IBDs; inflammatory bowel diseases; IEC; intestinal epithelial cells; IFN-γ; interferon-γ; IL-1β; interleukin-1β; IL-8; interleuki
Polyenephosphatidylcholine prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress
Keywords: ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; AOX; acyl-coenzyme A oxidase; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; COL1A1; collagen type 1 α1; COX-2; cyclo-oxygenase 2; CYP2E1; cytochrome P450 2E1; GAPDH; glyce
Tumour necrosis factor α mediates transient receptor potential vanilloid 1-dependent bilateral thermal hyperalgesia with distinct peripheral roles of interleukin-1β, protein kinase C and cyclooxygenase-2 signalling
Keywords: TNFα; TRPV1; Prostaglandins; IL-1β; Bilateral hyperalgesia; PKC;
Critical role of PBEF expression in pulmonary cell inflammation and permeability
Keywords: Pulmonary inflammation; Permeability; PBEF; Acute lung injury; IL-1β; IL-8; Epithelial cells; Endothelial cells; Inflammatory cytokines;
Sustained expression of interleukin-1β in mouse hippocampus impairs spatial memory
Keywords: neuroinflammation; water maze; IL-1βXAT transgenic mouse; hippocampus; AD; Alzheimer's disease; ANOVA; analysis of variance; CCR2; chemokine (C-C motif) receptor 2; COX; cyclooxygenase; CXCR2; chemokine (C-X-C motif) receptor 2; FIV-Cre; feline immunod
FoxO4 Inhibits NF-κB and Protects Mice Against Colonic Injury and Inflammation
Keywords: CD; Crohn's disease; DMEM; Dulbecco's modified Eagle's medium; EMSA; electrophoretic mobility shift assay; FITC; fluorescein isothiocyanate; FoxO; forkhead box transcription factor O; GFP; green fluorescent protein; IκB; inhibitor κB; IBD; inflammatory
Expression of cyclooxygenase-1/-2, microsomal prostaglandin-E synthase-1 and E-prostanoid receptor 2 and regulation of inflammatory mediators by PGE2 in the amoeboid microglia in hypoxic postnatal rats and murine BV-2 cells
Keywords: microglia; hypoxia; COX-1/-2; mPGES-1; EP2 receptor antagonist; PGE2; AA; arachidonic acid; AMC; amoeboid microglial cells; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; cPGES; cytosol
Association of IL-1B Gene Polymorphisms with Nasopharyngeal Carcinoma in a Chinese Population
Keywords: Genetic susceptibility; IL-1β; nasopharyngeal carcinoma; polymorphism;
Alveolar Macrophage Secretory Products Effect Type 2 Pneumocytes Undergoing Hypoxia-Reoxygenation
Keywords: AM; Alveolar macrophage; CINC; Cytokine induced neutrophil chemoattractant; ELISA; Enzyme linked immunosorbent assay; EMSA; Electrophoretic mobility shift assay; ERK1/2; Extracellular signal-regulated kinase; FBS; Fetal bovine Serum; H-R; Hypoxia/Reoxygen
NUMBL interacts with TAB2 and inhibits TNFα and IL-1β-induced NF-κB activation
Keywords: NF-κB; nuclear factor kappa B; IL-1β; interleukin-1β; TNF; tumor necrosis factor; NUMBL; homologous protein of numb like; TAK1; TGF-β activated kinase1; TAB2; TAK1-binding protein 2; TRAF6; TNF receptor-associated factor 6; TRAF2; TNF receptor-associa
Nodavirus increases the expression of Mx and inflammatory cytokines in fish brain
Keywords: Nodavirus; Sea bream (Sparus aurata); Sea bass (Dicentrarchus labrax); Immune system; Cytokines; TNFα; IL-1β; Mx;
Amitriptyline induces nuclear transcription factor-κB-dependent glutamate transporter upregulation in chronic morphine-infused rats
Keywords: amitriptyline; nuclear transcription factor-kB; glutamate transporters; excitatory amino acids; microdialysis; morphine tolerance; CSF; cerebrospinal fluid; EAAC1; excitatory amino acid carrier 1; GLAST; glutamate-aspartate transporter; GLT-1; glutamate t
Interpretation of Biomarkers of Bone Metabolism in Children: Impact of Growth Velocity and Body Size in Healthy Children and Chronic Disease
Keywords: BMI; Body mass index; BSAP; Bone-specific alkaline phosphatase; CV; Coefficient of variation; DPD; Urine deoxypyridinoline to creatinine ratio; DXA; Dual energy x-ray absorptiometry; IL-1β; Interleukin-1β; NFκB; Nuclear factor κB; OPG; Osteoprotegerin
Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation
Keywords: nAChR; neuronal nicotinic acetylcholine receptor; α7; alpha 7; UVR; ultraviolet radiation; IL-1β; interleukin 1 beta; IL-6; interleukin 6; TNFα; tumor necrosis factor alpha; SOCS3; suppressor of cytokine signaling 3; KO; knock-out.; Neuronal nicotinic;
The pharmokinetic limitations of antioxidant treatment for COPD
Keywords: COPD; chronic obstructive pulmonary disease; FEV1; forced expiratory volume in 1 s; IL-1β; interleukin-1-beta; GM-CSF; granulocyte monocyte colony stimulating factor; NF-κB; nuclear factor kappa B; MAPK; mitogen activated protein kinase; EGCG; epigallo
TGF-β1 reduces the heterogeneity of astrocytic cyclooxygenase-2 and nitric oxide synthase-2 gene expression in a stimulus-independent manner
Keywords: LPS; IFNγ; TNF-α; IL-1β; COX-2; NOS-2; Heterogeneity; Astrocytes; Nitric oxide; PGE2;
Loss of Adiponectin Promotes Intestinal Carcinogenesis in Min and Wild-type Mice
Keywords: Apc-Deficient MiceAdipokine; Colorectal Cancer; Chemoprevention; ACF; aberrant crypt foci; AMPK; AMP-activated protein kinase; AOM; azoxymethane; APN; adiponectin; CK2β; casein kinase 2β; IL-1β; interleukin-1β; MCP-1; monocyte chemotactic protein-1; m
μ-Opioid agonists inhibit the enhanced intracellular Ca2+ responses in inflammatory activated astrocytes co-cultured with brain endothelial cells
Keywords: astrocyte; calcium; endothelial cells; inflammatory activators; opioids; pain-transmitting peptides; BBB; blood-brain barrier; BSA; bovine serum albumin; [Ca2+]i; intracellular free calcium; CGRP; calcitonin gene-related peptide; DAMGO; [d-Ala2,NMe-Phe4
Differential expression of phosphorylated Ca2+/calmodulin-dependent protein kinase II and phosphorylated extracellular signal-regulated protein in the mouse hippocampus induced by various nociceptive stimuli
Keywords: pain; hippocampus; phospho-CaMKII; phospho-ERK; CaMK-II; Ca2+/calmodulin dependent protein kinase II; ERK; extracellular signal-regulated protein kinase; IL-1β; interleukin-1β; i.t.; intrathecal; PB; phosphate buffer; pCaMK-IIα; phosphor-Ca2+/calmoduli
Interleukin-1β impairs brain derived neurotrophic factor-induced signal transduction
Keywords: IL-1β; BDNF; Signal transduction; Cortical neurons;
The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1β, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice
Keywords: Neuropathic pain; Nitric oxide synthase; IL-1β; IL-6; Purinergic antagonism; PPADS;
Methylprednisolone treatment delays remote cell death after focal brain lesion
Keywords: glucocorticoids; inferior olive; pontine nuclei; glia; inflammation; remote degeneration; CTRL; control rats; DAPI; 4,6-diamidino-2-phenylindole; HCb; hemicerebellectomy; IL-1β; interleukin-1 beta; IO; inferior olive; MPSS; methylprednisolone sodium succ
Characterization of monocyte chemoattractant protein-1 expression following a kainate model of status epilepticus
Keywords: MCP-1; monocyte chemoattractant-1; BBB; blood-brain barrier; CNS; central nervous system; KA; kainic acid; IL-1β; interleukin-1β; TNF-α; tumor necrosis factor-α; CA3; Cornu Ammonis 3; EB dye; Evans blue dye; Monocyte chemoattractant protein-1; Blood
β Cell cytoprotection using lentiviral vector-based iNOS-specific shRNA delivery
Keywords: shRNA; Lentiviral vector; Rat insulinoma cells; Cytokines; IL-1β; iNOS;
The proinflammatory cytokines TNF-α and IL-1β impair economy of contraction in human myocardium
Keywords: Proinflammatory cytokines; Myocardium; Energy metabolism; TNF-α; IL-1β;
Tanshinone IIA inhibits atherosclerotic plaque formation by down-regulating MMP-2 and MMP-9 expression in rabbits fed a high-fat diet
Keywords: Tanshinone IIA; IL-1β; VCAM-1; MMP-2; MMP-9;
Rotenone-induced neurotoxicity of THP-1 cells requires production of reactive oxygen species and activation of phosphatidylinositol 3-kinase
Keywords: PD; Parkinson's disease; ROS; reactive oxygen species; PI3K; phosphatidylinositol 3-kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PKB; protein kinase B; COX-2; cyclooxygenase-2; PGE2; prostaglandin E2; CM; conditioned media
JNK-AP-1 pathway involved in interleukin-1β-induced calcitonin gene-related peptide secretion in human type II alveolar epithelial cells
Keywords: CGRP; IL-1β; AEII cell; JNK; AP-1;
Oxidative stress expression status associated to Helicobacter pylori virulence in gastric diseases
Keywords: BHI; brain heart infusion; cagA; cytotoxin-associated gene A; CAT; catalase; GPX; glutathione peroxidase; GAPDH; glyceraldehyde-3 phosphate dehydrogenase; GC; gastric carcinoma; GU; gastric ulcer; IFN-γ; interferon-γ; IL-1β; interleukin-1β; IL-6; inte
NMDA-induced interleukin-1β expression is mediated by nuclear factor-kappa B p65 in the retina
Keywords: Nuclear factor-κB; IL-1β; Antisense oligodeoxynucleotide; siRNA; N-methyl-d-aspartate; Retina;
Novel role for the N-terminus domain of the a2 isoform of vacuolar ATPase in interleukin-1β production
Keywords: Human; a2V-ATPase; Inflammation; Monocytes; IL-1β;
Tumour necrosis factor-α (TNF-α) increases nuclear factor κB (NFκB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells
Keywords: AP-1; Activator protein 1; BME-UV; Bovine mammary epithelium-University of Vermont; C/EBP; CCAAT/enhancer-binding protein; EMSA; Electrophoretic mobility shift assay; IL-1β; Interleukin-1 beta; IL-1ra; Interleukin-1 receptor antagonist; IL-8; Interleukin
Regulation of neuronal pituitary adenylate cyclase-activating polypeptide expression during culture of guinea-pig cardiac ganglia
Keywords: parasympathetic neurons; trophic factors; choline acetyltransferase; phosphatidylinositol 3-kinase; mitogen-activated protein kinase; explant culture; ANOVA; analysis of variance; bFGF; fibroblast growth factor basic; CARTp; cocaine- and amphetamine-regul
Contribution of two ionotropic purinergic receptors to ATP responses in submandibular gland ductal cells
Keywords: AEBSF; 4-(2-aminoethyl) benzenesulfonyl fluoride hydrochloride; BSA; bovine serum albumin; Bz-ATP; 2â²-3â²-O-(4-benzoylbenzoyl) adenosine 5â²-triphosphate; [Ca2+]i; intracellular concentration of calcium; EDTA; ethylene diamine tetraacetic acid; EGTA;
Intrastriatal administration of erythropoietin protects dopaminergic neurons and improves neurobehavioral outcome in a rat model of Parkinson's disease
Keywords: neuroprotection; inflammation; immunocytochemistry; striatum; substantia nigra; tyrosine hydroxylase; Alb; albumin; ANOVA; factor analysis of variance; CR3; complement receptor type 3; DAT; dopamine transporter; EPO; erythropoietin; GFAP; glial fibrillary
Syndecans in wound healing, inflammation and vascular biology
Keywords: Aβ; amyloid β protein; AD; Alzheimer's disease; AT-III; antithrombin-III; CAA; cerebral amyloid angiopathy; CS; chondroitin sulphate; EB; embryoid body; ECM; extracellular matrix; EGF; epidermal growth factor; ES cells; embryonic stem cells; FGF; fibrob
Amount of seminal IL-1β positively correlates to HIV-1 load in the semen of infected patients
Keywords: HIV; IL-1β; Semen; Heterosexual transmission; Mucosa; Viral load;
Cytokine assay on a cellular chip by combining collagen gel embedded culture with scanning electrochemical microscopy
Keywords: SECM-cytokine assay; Collagen cell chip; IL-1β; THP-1; HL-60;