IL-1β and TNF-α induce increased expression of CCL28 by airway epithelial cells via an NFκB-dependent pathway
Keywords: CCL28; IL-1β; TNF-α; Respiratory tract; NFκB; Asthma;
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Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: Implication in apoptosis resistance
Keywords: COX-2; cyclooxygenase-2; hsp60; heat shock protein 60; HFb; human foreskin fibroblasts; iPLA2; type VI calcium-independent phospholipase A2; AA; arachidonic acid; PMA; phorbol 12-myristate 13-acetate; IL-1β; interleukin-1β; Mitochondria; COX-2; iPLA2; A
Mildly oxidized low-density lipoprotein inhibits the in vitro induction of the specific antibody response to Candida albicans
Keywords: Oxidized LDL; Human B cells; Antigen-specific antibody response; Polyclonal immunoglobulin production; IL-1β; IgM anti-mLDL; Free radicals; Ab, antibody; FCS; fetal calf serum; IL; interleukin; Ig; immunoglobulin; LDL; low-density lipoprotein; mLDL; mild
Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2
Keywords: PMN; human polymorphonuclear leukocytes; CXCL8/IL-8; interleukin-8; CXCR1; interleukin-8 receptor 1; CXCR2; interleukin-8 receptor 2; GPCR; G protein-coupled receptor; NK; natural killer; LPS; bacterial endotoxin; C5a; fifth component of complement; fMLP;
Central cyclooxygenase inhibitors reduced IL-1β-induced hyperalgesia in temporomandibular joint of freely moving rats
Keywords: Cyclooxygenase inhibitor; Formalin; Hyperalgesia; IL-1β; TMJ;
Anti-bone resorption activity of deer antler aqua-acupunture, the pilose antler of Cervus korean TEMMINCK var. mantchuricus Swinhoe (Nokyong) in adjuvant-induced arthritic rats
Keywords: DAA; deer antler aqua-acupunture of pilose antler (Cervus korean TEMMINCK var. mantchuricus Swinhoe); BMC; lumbar bone mineral content; BÂ <Â D; lumbar bone density; RA; rheumatoid arthritis (RA); NeuAc; sialic acid; CII; type II collagen; CIA; CII-induce
Estrogen's effects on central and circulating immune cells vary with reproductive age
Keywords: Microglia; Reproductive senescence; IL-1β; TNF-α; LPS;
The cytosolic pattern-recognition receptor Nod2 and inflammatory granulomatous disorders
Keywords: Apaf-1; apoptotic protease activating factor 1; CARD; caspase-recruitment domain; IL-1β; interleukin 1β; LPS; lipopolysaccharide; MDP; muramyl-dipeptide; NF-κB; nuclear factor κB; NOD; nucleotide-binding oligomerization domain; PYD; pyrin domain; R ge
Acute stress suppresses pro-inflammatory cytokines TNF-α and IL-1β independent of a catecholamine-driven increase in IL-10 production
Keywords: Catecholamine; Cytokine; Immunosuppression; IL-1β; IL-10; Stress; TNF-α;
3,4-Methylenedioxymethamphetamine increases pro-interleukin-1β production and caspase-1 protease activity in frontal cortex, but not in hypothalamus, of Dark Agouti rats: Role of interleukin-1β in neurotoxicity
Keywords: MDMA; pro-IL-1β; caspase-1 protease; frontal cortex; hypothalamus; 5-HT neurotoxicity; ANOVA; analysis of variance; ECL; enhanced chemiluminescence; ICE; interleukin-1β converting enzyme; IL-1β; interleukin-1β; MDMA; 3,4-methylenedioxymethamphetamine;
MKK3/6-p38 MAPK negatively regulates murine MMP-13 gene expression induced by IL-1β and TNF-α in immortalized periodontal ligament fibroblasts
Keywords: IL-1β; Interleukin-1 beta; TNF-α; Tumor necrosis factor-alpha; MAPK; Mitogen-activated protein kinase; MKK; Mitogen-activated protein kinase kinase; siRNA; Silencing RNA; JNK; c-Jun N-terminal kinase; ERK; Extracellular-regulated protein kinase; MMP-13;
Curcumin protects human chondrocytes from IL-1β-induced inhibition of collagen type II and β1-integrin expression and activation of caspase-3: An immunomorphological study
Keywords: Chondrocyte; Curcumin; IL-1β; Collagen type II; β1-integrin; Activated caspase-3; Apoptosis;
Peripheral lipopolysaccharide administration impairs two-way active avoidance conditioning in C57BL/6J mice
Keywords: Lipopolysaccharide; LPS; Endotoxin; Cytokine; Interleukin-1β; IL-1β; Learning; Memory; Shuttlebox; Operant conditioning; Fear conditioning; Negative reinforcement;
Modulation of acute inflammation by targeting glycosaminoglycan-cytokine interactions
Keywords: Cytokines; Glycosaminoglycans; IFN-γ; IL-1β; IL-6; Inflammation; Peritoneal lavage; TNFα;
Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease
Keywords: AECOPD; Acute exacerbation of a chronic obstructive pulmonary disease; AECOPD-GW; Acute exacerbation of a chronic obstructive pulmonary disease with general ward treatment; AECOPD-ICU; Acute exacerbation of a chronic obstructive pulmonary disease with int
Signaling pathways of interleukin-1 actions in the brain: Anatomical distribution of phospho-ERK1/2 in the brain of rat treated systemically with interleukin-1β
Keywords: interleukin-1β; extracellular signal-regulated kinase 1 and 2; inflammation; brain; neuroanatomy; ACA(d/v); anterior cingulate area (dorsal part/ventral part); AI(d/p/v); agranular insular area (dorsal part/posterior part/ventral part); AP; area postrema
Recombinant human interferon-α does not alter reward behavior, or neuroimmune and neuroendocrine activation in rats
Keywords: CNS; central nervous system; DA; dopamine; DOPAC; 3,4 dihydroxyphenylacetic acid; FST; forced swim test; 5-HIAA; 5-hydroxyindole acetic acid; 5-HT; 5-hydroxytryptophan (serotonin); HPA axis; hypothalamic-pituitary-adrenal axis; HPLC; high-performance
Downregulation of IL-4-induced signalling in hippocampus contributes to deficits in LTP in the aged rat
Keywords: Age; IL-4; IL-1β; Long-term potentiation (LTP); Dentate gyrus; JAK; STAT; c-Jun N-terminal kinase (JNK);
Phenotypic characterization of chondrosarcoma-derived cell lines
Keywords: Chondrocyte; Cell line; Expression analysis; Functional genomics; ADAMTS; a disintegrin and metalloproteinase with thrombospondin type 1 motif; Col; collagen; IL-1β; interleukin 1β; MMP; matrix metalloproteinases; OA; osteoarthritic; qPCR; quantitative
Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collagen-induced arthritis
Keywords: A.B.; Alcian Blue; AMPA; dl-α-amino-3-hydroxy-5-methylisoxasole-4-propionate; BrdU; 5-bromo-2â²-deoxyuridine; CIA; collagen-induced arthritis; EAAC1; excitatory amino acid carrier-1; EAAT; excitatory amino acid transporter; GAPDH; glyceraldehydes-3-phos
Potential markers of oxidative stress in stroke
Keywords: 4-HNE; 4-hydroxynonenal; 8-OH-dG; 8-hydroxydeoxyguanosine; CEOOH; cholesteryl ester hydroperoxides; COX; cyclooxygenase; CSF; cerebrospinal fluid; CT; computerized tomography; ELISA; enzyme-linked immunosorbent assay; eNOS; endothelial NOS; ESR; electron
Inhibitory effect of Buthus martensi Karsch extracts on interleukin-1β-induced expression of nitric oxide (NO) synthase and production of NO in human chondrocytes and LPS-induced NO and prostaglandin E2 production in mouse peritoneal macrophages
Keywords: BMK; Buthus martensi Karsch; (IL-1β); interleukin-1β; PGE2; prostaglandin E2; NO; nitric oxide; iNOS; inducible NO synthase; COX-2; cyclooxygenase-2; COX-1; cyclooxygenase-1; NF-κB; nuclear factor-κB; AP-1; activation protein-1; OA; osteoarthritis; ec
Production of antibodies to canine IL-1β and canine TNF to assess the role of proinflammatory cytokines
Keywords: OA; osteoarthritis; rcan; recombinant canine; Iscove's FBS medium; Iscove's modified Dulbecco's minimum essential medium containing fetal bovine serum (5%) and gentamycine; TMB; 3,3â²,5,5â²-tetramethyl-benzidine; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-di
Prostaglandin E2 modulation of gene expression in an Atlantic salmon (Salmo salar) macrophage-like cell line (SHK-1)
Keywords: Real-time PCR; Gene expression; Cytokines; IL-1β; TNFα; MHC I; MHC II; TGFβ; COX-2; Inflammation; Macrophage-like cell line; Prostaglandin E2; Atlantic salmon;
HDAC inhibition prevents NF-κB activation by suppressing proteasome activity: Down-regulation of proteasome subunit expression stabilizes IκBα
Keywords: SCFA; short chain fatty acid; HDAC; histone deacetylase; NF-κB; nuclear factor-κB; IκB; inhibitor-κB; IKK; IκB kinase; TNF-α; tumor necrosis factor-α; IL-1β; interleukin-1β; BA; butyrate; TSA; trichostatin A; CT-L; chymotrypsin-like; T-L; trypsyn
Response of mouse skin to tattooing: use of SKH-1 mice as a surrogate model for human tattooing
Keywords: Tattoo; Skin; Lymph node; NF-κB; COX-1; COX-2; ODC; IL-1β; IL-10;
Administration of yeast glucan enhances survival and some non-specific and specific immune parameters in carp (Cyprinus carpio) infected with Aeromonas hydrophila
Keywords: Carp; Macrophage; Phagocytosis; Opsonin; NBT assay; Complement; Antibody; IL-1β; Aeromonas hydrophila;
Innate immune traits differ between Meishan and Large White pigs
Keywords: mAb; monoclonal antibody; IL-1β; interleukin-1β; TNFα; tumour necrosis factor α; MHC; major histocompatibility complex; FITC; fluorescein isothiocyanate; EDTA; ethylene diamine tetraacetic acid; PBS; phosphate-buffered saline; PMA; phorbol 12-myristat
Repression by oxidative stress of iNOS and cytokine gene induction in macrophages results from AP-1 and NF-κB inhibition mediated by B cell translocation gene-1 activation
Keywords: BSO; buthionine sulfoximine; Btg-1; B-cell translocation gene-1; GFP; green fluorescent protein; GSH; glutathione; iNOS; inducible nitric oxide synthase; IL-1β; interleukin-1β; IL-6; interleukin-6; MEM; minimum essential medium; PBS; phosphate-buffered
A quantitative in situ hybridization and polymerase chain reaction study of microglial-macrophage expression of interleukin-1β mRNA following permanent middle cerebral artery occlusion in mice
Keywords: cytokines; focal cerebral ischemia; stroke; astrocytes; immunohistochemistry; AP; alkaline phosphatase; BCIP; 5-bromo-4-chloro-3-indolyl phosphate; CAST; Computer Assisted Stereological Test; DAB; diaminobenzidine; EDTA; ethylenediaminetetraacetate; FCS;
Role of peroxidases in Parkinson disease: a hypothesis
Keywords: COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; IFN-γ; interferon-γ; IL-1β; interleukin-β; LPS; lipopolysaccharide; MAO-B; monoamine oxidase B; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPDP; 1-methyl-4-phenyl-1,2-dihydropyridine; MPP+; 1-
Statins potentiate the IFN-γ-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells
Keywords: C/EBP-β; CAAT-enhancer-binding protein-β; cPLA2; cytosolic phospholipase A2; DRB; 5,6-Dichloro-1-β-d-ribofuranosylbenzimidazole; ELISA; enzyme linked immunosorbent assay; ERK; extracellular signal-regulated kinase; FCS; fetal calf serum; FPP; farnesyl
Cytokines, stressors, and clinical depression: Augmented adaptation responses underlie depression pathogenesis
Keywords: FH; Fawn Hooded; HPC; hippocampus; HPA; hypothalamus-pituitary-adrenal axis; 5-HIAA; 5-hydroxyindoleacetic acid; IL-1α; interleukin-1 alpha; IL-1β; interleukin-1 beta; IL-1ra; interleukin-1 receptor antagonist; IL-2; interleukin-2; IL-6; interleukin-6;
The role of inflammation in Alzheimer's disease
Keywords: αBTx; α-bungarotoxin; Aβ; beta-amyloid protein; ACh; acetylcholine; AChBP; acetylcholine-binding protein; AChR; nicotinic acetylcholine receptor; AD; Alzheimer's disease; AICD; amyloid precursor protein intracellular domain; AP; amyloid P; APP; amyloid
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
Keywords: DEP; diesel exhaust particles; PM; particulate matter; PD; Parkinson's disease; AD; Alzheimer's disease; ROS; reactive oxygen species; NO; nitric oxide; TNFα; tumor necrosis factor-alpha; TH; tyrosine hydroxylase; Aβ; beta-amyloid; LPS; lipopolysacharid
Protein aggregation and its inhibition in biopharmaceutics
Keywords: Protein aggregation; Aggregation mechanism; Protein refolding; Protein formulation; Protein stabilization; Aβ; amyloid β peptide; BSA; bovine serum albumin; CAB; carbonic anhydrase B; CD; circular dichroism; rConIFN; recombinant consensus α-interferon;