Keywords: عامل تنظیمی اینترفرون 3; IRF3; Interferon regulatory factor 3; GFP; green fluorescent protein; PRNT; plaque reduction neutralization test; VSV; vesicular stomatitis virus; PFU; plaque forming units; moi; multiplicity of infection; LV; lentiviral vector; ZIKV; Zika virus; TBEV; ti
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Keywords: عامل تنظیمی اینترفرون 3; APCs; antigen-presenting cells; DAMPs; danger-associated molecular patterns; DCs; Donor-derived dendritic cells; ET; endotoxin tolerance; FFA; free fatty acids; Gsdmd; gasdermin D; HDAC11; Histone deacetylase 11; HFD; high fat diet; HMGB1; high mobility g
Keywords: عامل تنظیمی اینترفرون 3; ÎÏ; mitochondrial membrane potential; Bcl-2; B-cell CLL/lymphoma 2; BH; Bcl-2 homology; CJ; crista junction; CM; cristae membrane; Erv1; essential for respiration and viability; ETC; electron transport chain; FAD; flavin adenine dinucleotide; FADH2; fla
Keywords: عامل تنظیمی اینترفرون 3; AD; Alzheimer's disease; TLRs; toll-like receptors; AβPP; amyloid-β protein precursor; NSAIDs; non-steroidal anti-inflammatory drugs; CNS; central nervous system; TNF-α; tumor necrosis factor-α; IL-1β; interleukin 1-β; IL-6; interleukin-6; NO; nit
Keywords: عامل تنظیمی اینترفرون 3; AP1; Activator protein 1; cAMP; Cyclic adenosine monophoshate; CXCR; Cytokine receptors; CRTH2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; DAMPs; Damage-associated molecular pattern; EtBr; Ethidium Bromide; IgE; Immunoglobulin E;
Keywords: عامل تنظیمی اینترفرون 3; RA; rheumatoid arthritis; DCs; dendritic cells; TolDCs; tolerogenic dendritic cells; NSAIDs; non-steroidal anti-inflammatory drugs; GC; glucocorticoids; DMARDs; disease-modifying anti-rheumatic drugs; TLRs; toll-like receptors; CLRs; cell surface C-type l
Keywords: عامل تنظیمی اینترفرون 3; AJ; adherens junction; APC; adenomatous polyposis coli; ARD; armadillo repeat domain; ARVC; arrhythmogenic right ventricular cardiomyopathy; Bsk; Basket; CaM; calmodulin; Cav-1; caveolin-1; CCM; cerebral cavernous malformations; Ccm3; cerebral cavernous m
Keywords: عامل تنظیمی اینترفرون 3; Virus; Innate immunity; Recognition; Interferon; Interferon regulatory factor 3;
Keywords: عامل تنظیمی اینترفرون 3; CD14; cluster of differentiation 14; dsRNA; double stranded ribonucleic acid; IFN; interferon; IL; interleukin; IRAK; interleukin-1 receptor-associated kinase; IRF3; interferon regulatory factor 3; LBP; lipopolysaccharide-binding protein; LPS; lipopolysac
Maintenance of cyclic GMP-AMP homeostasis by ENPP1 is involved in pseudorabies virus infection
Keywords: عامل تنظیمی اینترفرون 3; Pseudorabies virus; Ectonucleotide pyrophosphatase phosphodiesterase 1; Cyclic GMP-AMP; Interferon β; Nuclear factor κB; Interferon regulatory factor 3;
Oral cancer-derived exosomal NAP1 enhances cytotoxicity of natural killer cells via the IRF-3 pathway
Keywords: عامل تنظیمی اینترفرون 3; Oral cancer; Head and neck cancer; Exosome; Tumor-derived exosome; Natural killer cell; Interferon regulatory factor 3; IRF-3; NF-κB-activating kinase-associated protein 1; NAP1;
STING positively regulates human ORMDL3 expression through TBK1-IRF3-STAT6 complex mediation
Keywords: عامل تنظیمی اینترفرون 3; ORMDL3; orosomucoid 1-like protein 3; GWAS; genome-wide association studies; EBV; Epstein-Barrvvirus; HRV; human rhinovirus; RSV; respiratory syncytial virus; STING; Stimulator of interferon genes; TLR; Toll-like receptors; NF-κB; nuclear factor κB; IFN
Molecular mechanism of LPS-induced TNF-α biosynthesis in polarized human macrophages
Keywords: عامل تنظیمی اینترفرون 3; TTP; tristetraprolin; TRIF; TIR-domain-containing adapter-inducing interferon-β; TRAM; TRIF-related adapter molecule; IRF3; interferon regulatory factor 3; IFNAR; interferon-α/β receptor; ActD; actinomycin D; TIRAP; TIR-domain-containing adapter protei
In vitro models for deciphering the mechanisms underlying the sexual transmission of viruses at the mucosal level
Keywords: عامل تنظیمی اینترفرون 3; BSA; Bovin Serum Albumin; CCL5; Chemokine Ligand 5; CCR7; Chemokine Receptor Type 7; CD; Cluster of Differentiation; CMV; Cytomegalovirus; DC-SIGN; Dendritic Cell-Specific ICAM-Grabbing Non-integrin; DNA; Deoxyribonucleic Acid; EDTA; Ethylenediaminetetraa
The mechanisms of Ag85A DNA vaccine activates RNA sensors through new signal transduction
Keywords: عامل تنظیمی اینترفرون 3; DC; dendrite cells; BMDCs; bone-marrow dendrite cells; APC; antigen presenting cell; PRR; pattern recognition receptor; PAMPs; pathogen-associated molecular patterns; RIG-I; retinoic acid-inducible gene I; Mda-5; melanoma differentiation associated gene-5
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway
Keywords: عامل تنظیمی اینترفرون 3; ALI; acute liver injury; AST; aspartate transaminase; CD14; cluster of differentiation 14; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cysteine ligase modifier subunit; GSH; reduced glutathione; HO-1; hemeoxygenase-1; iNOS; inducibl
Effects of intravesical therapy with platelet-rich plasma (PRP) and Bacillus Calmette-Guérin (BCG) in non-muscle invasive bladder cancer
Keywords: عامل تنظیمی اینترفرون 3; BC; bladder cancer; BCG; Bacillus Calmette-Guerin; bFGF; basic fibroblast growth factor; BSA; bovine serum albumin; EGF; epidermal growth factor; GFs; growth factors; HGF; hepatocyte growth factor; HRP; horseradish peroxidase; IFN-γ; interferon-gamma; IG
Tripartite motif-containing (TRIM) 21 negatively regulates intestinal mucosal inflammation through inhibiting TH1/TH17Â cell differentiation in patients with inflammatory bowel diseases
Keywords: عامل تنظیمی اینترفرون 3; Tripartite motif-containing 21; inflammatory bowel disease; CD4+ T cells; mucosal inflammation; TH1; TH17; A-CD; Active Crohn disease; A-UC; Active ulcerative colitis; CD; Crohn disease; CDAI; Crohn's Disease Activity Index; HC; Healthy control subject; I
Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease
Keywords: عامل تنظیمی اینترفرون 3; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BW; body weight; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic-reticulum; FBS; fetal bovine serum; FFA; free fatty acid; GCK; glucokinase; p-GSK3β; pho
Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy
Keywords: عامل تنظیمی اینترفرون 3; STING agonist; PBAE nanoparticle formulation; Cancer immunotherapy; CDNs; Cyclic dinucleotides; STING; Stimulator of Interferon Receptor; PBAEs; poly(beta-amino ester)s; IFN; interferon; SEAP; secreted embryonic alkaline phosphatase; cGAS; cyclic GMP-AMP
Developmental and extrahepatic physiological functions of SREBP pathway genes in mice
Keywords: عامل تنظیمی اینترفرون 3; AAV; adeno-associated virus; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; ADD1; adipocyte determination- and differentiation-dependent factor 1; APP; amyloid precursor protein; Api6; apoptosis inhibitor 6; ApoE; apolipoprotein E; ATF6; activati
STING Signaling Promotes Inflammation in Experimental Acute Pancreatitis
Keywords: عامل تنظیمی اینترفرون 3; Mouse Model; Apoptosis; Signal Transduction; Innate Immunity; ACS; acinar cell culture supernatant; AP; acute pancreatitis; BM; bone marrow; BMDM; BM-derived macrophages; CDE; choline-deficient diet supplemented with DL-ethionine; cGAS; cyclic GMP-AMP syn
Neuroprotective effect of monophosphoryl lipid A, a detoxified lipid A derivative, in photothrombotic model of unilateral selective hippocampal ischemia in rat
Keywords: عامل تنظیمی اینترفرون 3; MPL; monophosphoryl lipid A; LPS; lipopolysaccharide; TLR4; toll like receptor 4; i.c.v; intracerebroventricular; TTC; triphenyltetrazolium chloride; RAWM; radial arm water maze test; PA; passive avoidance test; NF-κB; nuclear factor kappa beta; TNF-α;
Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women
Keywords: عامل تنظیمی اینترفرون 3; BSA; bovine serum albumin; IFN; interferon; IR; insulin resistance; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated genes; ISRE; interferon-sensitive/stimulated response element; LPS; lipopolysaccharides; MyD88; myeloid differentiation pr
Human microglia and astrocytes express cGAS-STING viral sensing components
Keywords: عامل تنظیمی اینترفرون 3; AMP; adenosine monophosphate; ATCC; American type tissue collection; ANOVA; analysis of variance; BDNA; B-form DNA; CNS; central nervous system; cDNA; complementary DNA; cGAS; cyclic GMP-AMP synthase; DAI; DNA-dependent activator of interferon-regulatory
Intracellular DNA sensing pathway of cGAS-cGAMP is decreased in human newborns and young children
Keywords: عامل تنظیمی اینترفرون 3; CBMCs; cord blood mononuclear cells; CBP; CREB-binding protein; cGAS; cyclic GMP-AMP synthase; cGAMP; cyclic GMP-AMP; EBV; Epstein-Barr virus; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HCMV; human cytomegalovirus; HSV-1; herpes simplex virus type 1
Bis(monoacylglycero)phosphate inhibits TLR4-dependent RANTES production in macrophages
Keywords: عامل تنظیمی اینترفرون 3; ABC; ATP-binding cassette transporter; BMP; bis(monoacylglycerophosphate); IL-6; interleukin 6; IRF3; interferon regulatory factor 3; LPS; lipopolysaccharide; oxLDL; oxidized low-density lipoprotein; MBCD; methyl-β-cyclodextrin; MyD88; myeloid differenti
Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure
Keywords: عامل تنظیمی اینترفرون 3; IFN I; type I interferon(s); IFI16; interferon-inducible protein 16; cGAMP; cyclic GMP-AMP; cGAS; cGAMP synthase; STING; stimulator of interferon genes; TBK1; TANK-binding kinase 1; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated genes; P
Zebrafish STAT6 negatively regulates IFNÏ1 production by attenuating the kinase activity of TANK-binding kinase 1
Keywords: عامل تنظیمی اینترفرون 3; STAT6; Negative regulator; Interferon; TBK1; Zebrafish; CIP; calf intestinal phosphatase; CPE; cytopathic effect; EPC; epithelioma papulosum cyprini; GAS; interferon gamma activated sequence; IFN; interferon; IRF; IFN regulatory factor; IRF3; interferon r
Poly (I:C) impairs NO donor-induced relaxation by overexposure to NO via the NF-kappa B/iNOS pathway in rat superior mesenteric arteries
Keywords: عامل تنظیمی اینترفرون 3; 1400W; N-([3-(aminomethyl)phenyl]methyl)ethanimidamide dihydrochloride; ACh; acetylcholine; ANOVA; analysis of variance; BAY41-2272; 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine; BAY58-2667; 4-[[(4-carboxybu
LXRα represses LPS-induced inflammatory responses by competing with IRF3 for GRIP1 in Kupffer cells
Keywords: عامل تنظیمی اینترفرون 3; Liver X receptor; Kupffer cell; Interferon regulatory factor 3; Glucocorticoid receptor-interacting protein 1; Nuclear factor-kappa B
ASF1a enhances antiviral immune response by associating with CBP to mediate acetylation of H3K56 at the Ifnb promoter
Keywords: عامل تنظیمی اینترفرون 3; ASF1a; anti-silencing function 1a; CBP; CREB binding protein; TLRs; Toll-like receptors; RLRs; RIG-I-like receptors; IRF3; interferon regulatory factor 3; VSV; vesicular stomatitis virus; SEV; simian enterovirus; IFN-β; interferon beta; QPCR; quantitativ
The function of feline stimulator of interferon gene (STING) is evolutionarily conserved
Keywords: عامل تنظیمی اینترفرون 3; Feline; STING; Type I IFN; Activation; STING; Stimulator of interferon genes; ER; Endoplasmic reticulum; IRF3; Interferon regulatory factor 3; NF-κB; Nuclear factor kappa-light-chain-enhancer of activated B cells; JNK; c-jun N-terminal kinase; AP-1; Acti
Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes
Keywords: عامل تنظیمی اینترفرون 3; PUVA; 8-methoxypsoralen plus UVA; RIG-1; retinoic acid induced gene 1; MDA5; melanoma differentiation associated gene 5; MAVS; mitochondrial antiviral signaling protein; TBK; TANK-binding kinase 1; IKKε; inhibitor of kappaB kinase epsilon; IRF3; interfer
ReviewUpdate on hepatitis E virology: Implications for clinical practice
Keywords: عامل تنظیمی اینترفرون 3; 7mG; 7-methylguanylate; CSF; cerebrospinal fluid; gt; genotype; HCV; hepatitis C virus; HEV; hepatitis E virus; ESCRT; endosomal sorting complexes required for transport; IFN; interferon; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated ge
Murine gammaherpesvirus targets type I IFN receptor but not type III IFN receptor early in infection
Keywords: عامل تنظیمی اینترفرون 3; EBV; Epstein-Barr virus; FBS; fetal bovine serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HHV-4; human herpesvirus 4; HHV-8; human herpesvirus 8; hpi; hours post infection; IFN; interferon; IFNAR; interferon α/β receptor; IFN-λR; interferon la
Rupestonic acid derivative YZH-106 suppresses influenza virus replication by activation of heme oxygenase-1-mediated interferon response
Keywords: عامل تنظیمی اینترفرون 3; IAV; influenza A virus; HO-1; heme oxygenase-1; Nrf2; erythroid 2-related factor 2; ISGs; IFN-stimulated genes; RdRp; RNA-dependent RNA polymerase; TLRs; toll-like receptors; RLR; RIG-I-like receptors; MKP5; MAPK phosphatase 5; IRF3; interferon regulatory
Testicular immunoregulation and spermatogenesis
Keywords: عامل تنظیمی اینترفرون 3; BTB; blood-testis barrier; EAO; experimental autoimmune orchitis; Gas6; growth arrest-specific gene 6; IRF3; interferon regulatory factor 3; IPS-1; IFN-β; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinases; MDA5; melanoma differentiation-
Arsenic programmes cellular genomic-immunity through miR-2909 RNomics
Keywords: عامل تنظیمی اینترفرون 3; miRNA; MicroRNA; PBMCs; Peripheral blood mononuclear cells; CYLD; Cylindromatosis; KLF4; Kruppel-like factor4; NFκB; Nuclear factor kappa B; FCS; Foetal Calf Serum; As; Arsenic; IFNβ; Interferon beta; APOBEC3G; Apolipoprotein B mRNA-editing, enzyme-cata
Effects of the nuclear localization of the Npro protein of classical swine fever virus on its virulence in pigs
Keywords: عامل تنظیمی اینترفرون 3; Classical swine fever virus; Npro protein; Interferon regulatory factor 3; Nuclear localization; Virulence;
Glycyrrhizin inhibits lipopolysaccharide-induced inflammatory response by reducing TLR4 recruitment into lipid rafts in RAW264.7 cells
Keywords: عامل تنظیمی اینترفرون 3; Cytokine; Glycyrrhizin; Nuclear factor κB; Interferon regulatory factor 3; Toll-like Receptor 4; Lipid raft;
Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway
Keywords: عامل تنظیمی اینترفرون 3; AP; action potential; APD; action potential duration; DAD; delayed after depolarization; IRAK1/4; interleukin-1 receptor-associated kinase 4; IRF3; interferon regulatory factor 3; Ito; transient outward potassium current; KChIP2; Kv channel-interacting pr
The intricate interplay between RNA viruses and NF-κB
Keywords: عامل تنظیمی اینترفرون 3; ss; single-stranded; ds; double-stranded; HTLV; human T cell leukemia virus; SARS; severe acute respiratory syndrome; IAVs; influenza A viruses; IFN; interferon; IRF3; interferon regulatory factor 3; NF-κB; nuclear factor κB; TLRs; toll-like receptors;
Message in a bottle: lessons learned from antagonism of STING signalling during RNA virus infection
Keywords: عامل تنظیمی اینترفرون 3; BiFC; bimolecular fluorescence complementation; CARD; caspase activation and recruitment domain; cGAMP; cyclic GMP-AMP; cGAS; cyclic GMP-AMP synthase; DC; dendritic cell; DUB; deubiquitinase; hSTING; human STING; IFN; interferon; IRF-3; interferon regulat
Cyanidin-3-O-β-glucoside ameliorates lipopolysaccharide-induced acute lung injury by reducing TLR4 recruitment into lipid rafts
Keywords: عامل تنظیمی اینترفرون 3; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IL-6; interleukin-6; IL-1β; interleukin-1β; NF-κB; nuclear factor-kappaB; IRF3; interferon regulatory factor 3; ELISA; enzyme-linked immunosorbent assay; Cyanidin-3-O-β-glucoside; TLR4; Lipid
Suppression of TRIF-dependent signaling pathway of toll-like receptors by (E)-1-(2-(2-nitrovinyl)phenyl)pyrrolidine
Keywords: عامل تنظیمی اینترفرون 3; Toll-like receptor; Lipopolysaccharide; Polyinosinic-polycytidylic acid; Interferon regulatory factor 3; (E)-1-(2-(2-nitrovinyl)phenyl)pyrrolidine;
Understanding the molecular mechanism(s) of hepatitis C virus (HCV) induced interferon resistance
Keywords: عامل تنظیمی اینترفرون 3; HCV; hepatitis C virus; UTR; untranslated regions; IFN; interferon; ISG; interferon stimulatory genes; IRES; internal ribosome entry site; IFNAR; IFN-α receptor; STAT; signal transducer and activator of transcription; TLR3; toll like receptor 3; DsRNA; d
Mouse gammaherpesvirus-68 infection acts as a rheostat to set the level of type I interferon signaling in primary macrophages
Keywords: عامل تنظیمی اینترفرون 3; Type I interferon; Gammaherpesvirus; Interferon regulatory factor 3; RTA; Macrophage;
Interleukin-10 activates Toll-like receptor 4 and requires MyD88 for cardiomyocyte survival
Keywords: عامل تنظیمی اینترفرون 3; Anti-IL-10R; antibody to interleukin-10 receptor; CD14; cluster differentiation 14; Ikk; antibody to interleukin-10 receptor; IkkB; inhibitory kinase B; IL-1β; interleukin-1β; IL-10; interleukin-10; IRF3; interferon regulatory factor 3; ISRE; interferon
A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer
Keywords: عامل تنظیمی اینترفرون 3; BiFC; bimolecular fluorescence complementation; BRET; bioluminescence resonance energy transfer; CARD; caspase activation and recruitment domain; HCV; hepatitis C virus; HEK; human embryonic kidney; HR1; 4,3 hydrophobic heptad repeat region 1; IFN-β; int