دانلود مقالات ISI درباره Ipsc + ترجمه فارسی

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Neuroscience Forefront ReviewEarly gamma oscillations

Keywords: CSD; current source density; dLGN; dorsal lateral geniculate nucleus; EEG; electroencephalograms; EGO; early gamma oscillation; EPSC; excitatory postsynaptic current; IPSC; inhibitory postsynaptic current; L2/3; layer 2/3; L4; layer 4; LFP; local field po

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

مدل سازی بیماری هانتینگتون با سلول های بنیادی پلورپوفتون القا شده

Modeling Huntington's disease with induced pluripotent stem cells

Keywords: Huntington's disease; Induced pluripotent stem cells; IPSC; MSN; Stem cell models; Neurodegenerative disease;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

مکانیسم مغز برای تصمیم گیری ادراکی و پاداش

Brain mechanisms for perceptual and reward-related decision-making

Keywords: 2AFC; 2-alternative forced-choice; AMPA; α-amino-3-hydroxy-5-methyl-4-isoazoleproprionic acid; DDM; drift diffusion model; dlPFC; dorso-lateral prefrontal cortex; EPSC; excitatory post-synaptic current; ER; error rate; FEF; frontal eye-field; FF; feedfor

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2013 سفارش ترجمه

تولید یک خط iPSC انسانی از یک بیمار مبتلا به سندرم لی

Generation of a human iPSC line from a patient with Leigh syndrome

Keywords: Leigh syndrome; Induced pluripotent stem cells; iPSC; iPS cells; MT-ND5

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

تولید یک خط iPSC کنترل انسانی با یک پس زمینه هپلو گروپ U میتوکندری اروپایی

Generation of a human control iPSC line with a European mitochondrial haplogroup U background

Keywords: Defects of intergenomic communication; Induced pluripotent stem cells; iPSC; iPS cells; POLG

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

ترکیبات سیتوپلاسمی Dynactin در نورون های مثبت تیروسین هیدروکسیلاز مثبت حاصل از iPSC از یک بیمار مبتلا به سندرم پرری

Cytoplasmic aggregates of dynactin in iPSC-derived tyrosine hydroxylase-positive neurons from a patient with Perry syndrome

Keywords: iPSC; Tyrosine hydroxylase-positive neuron; Aggregate; DCTN1; Perry syndrome

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A Human Stem Cell-Based System to Study the Role of TP63 Mutations in Ectodermal Dysplasias

Keywords: AEC; ankyloblepharon-ectodermal defects-cleft lip/palate syndrome; GC; gene corrected; iPSC; induced pluripotent stem cell; iPSC-K; induced pluripotent stem cell-derived keratinocyte;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2018 سفارش ترجمه

Modified T-cells (using TCR and CTAs), chimeric antigen receptor (CAR) and other molecular tools in recent gene therapy

Keywords: Clinical trials; Disorders; Gene therapy; Molecular biology; Pharmacotherapy; Vector; PID; Primary immunodeficiencies; ADA; Adenosine deaminase; CAR; Chimeric antigen receptors; TCR; T cell receptor; CTAs; Cancer testis antigens; TALEN; Transcription acti

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Enhanced chondrogenesis differentiation of human induced pluripotent stem cells by MicroRNA-140 and transforming growth factor beta 3 (TGFβ3)

Keywords: Chondrocytes; iPSC; microRNA; TGFβ3; Osteoarthritis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Cephalosporin antibiotics are weak blockers of GABAa receptor-mediated synaptic transmission in rat brain slices

Keywords: Cephalosporins; Antibiotic-induced seizure; Entorhinal cortex; GABAa receptor; Epilepsy; IPSC;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

A new model to study cell-to-cell transfer of αSynuclein in vivo

Keywords: Parkinson's disease; αSynuclein; Cell-to-cell transfer; Sub-cellular compartments; Endoplasmic reticulum; Dopaminergic neuron; αSyn; αSynuclein; αSyn-CGFP; αSynuclein fused to carboxy-terminal; AAV; adeno-associated virus; BiFC; Bi-molecular Fluoresc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

The development of induced pluripotent stem cell-derived mesenchymal stem/stromal cells from normal human and RDEB epidermal keratinocytes

Keywords: α-MEM; alpha minimum essential medium; bFGF; basic fibroblast growth factor; BIO; 6-bromoindirubin-3′-oxime; BM-MSCs; bone marrow-derived MSCs; BMP4; bone morphogenetic protein 4; C57BL/6; C57BL/6 mouse; CM; conditioned medium; DAPI; 4′,6-diamidino-2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood

Keywords: AHC; alternating hemiplegia of childhood; RMP; resting membrane potential; iPSC; induced pluripotent stem cells; NGN2; neurogenin-2; RFP; red fluorescence protein; TetO; tetracycline inducible promoter; AHP; afterhyperpolarization; ATP1A3; Alternating hem

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A simple and efficient feeder-free culture system to up-scale iPSCs on polymeric material surface for use in 3D bioprinting

Keywords: Culture surface; Feeder-free; iPSC; Chitosan; Polyurethane;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells

Keywords: PD; Parkinson's disease; iPSC; induced pluripotent stem cells; 6-OHDA; 6-hydroxydopamine; DAT; dopamine transporter; ROS; reactive oxygen species; TUNEL; terminal deoxynucelotidyl transferase-mediated deoxyuridine triphosphate nick end labeling; CCK-8;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Human stem cell modeling in neurofibromatosis type 1 (NF1)

Keywords: NF1; Neurodevelopment; Neurofibroma; iPSC; Stem cell; Optic pathway glioma; Retinal ganglion cell; Microglia; Tumor;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

Keywords: iPSC; T2DM; ChIP-seq; PDX1; SNPs; PP; GWAS;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Altered glutamate response and calcium dynamics in iPSC-derived striatal neurons from XDP patients

Keywords: XDP; iPSC; Spiny projection neurons; Electrophysiology; AMPA receptor; Calcium dynamics;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity

Keywords: Antipsychotic; Excitatory-inhibitory imbalance disorders; GABAAR; Prefrontal transmission; Quercetin; AAV; Adeno-associated virus; ACSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; DAPI; 4,6-d

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Efficient production of erythroid, megakaryocytic and myeloid cells, using single cell-derived iPSC colony differentiation

Keywords: iPSC; Differentiation; Erythroid; Hematopoietic; Megakaryocytic; Myeloid;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Increased motor neuron resilience by small molecule compounds that regulate IGF-II expression

Keywords: ALS; amyotrophic lateral sclerosis; ChAT; choline acetyltransferase; FTD; frontotemporal dementia; IGF-II; insulin-like growth factor II; IGF-IIR; IGF-II/cation-independent mannose-6-phosphate receptor; IGF-IR; IGF-I receptor; isl-1/2; islet 1 and 2; iPSC

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Pan-Genotype Hepatitis E Virus Replication in Stem Cell-Derived Hepatocellular Systems

Keywords: HLCs; Antiviral; Primary Isolates; Personalized Medicine; ALB; albumin; AFP; alpha-fetoprotein; bFGF; basic fibroblast growth factor; BM; basal medium; CsA; cyclosporine A; DE; definitive endoderm; DMSO; dimethyl sulfoxide; Dox; doxycycline; ESC; embryoni

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Pluripotent stem cell models of Blau syndrome reveal an IFN-γ-dependent inflammatory response in macrophages

Keywords: Blau syndrome; nucleotide-binding oligomerization domain 2; nuclear factor κB; IFN-γ; disease-specific induced pluripotent stem cells; ChIP; Chromatin immunoprecipitation; DAPI; 4′-6-Diamidino-2-phenylindole dihydrochloride; gRNA; Guide RNA; GSEA; Gen

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Marfan syndrome; A connective tissue disease at the crossroads of mechanotransduction, TGFβ signaling and cell stemness

Keywords: Cardiomyopathy; Fibrillin; Marfan syndrome; Mechanotransduction; Osteopenia; Stem cell niche; TGFβ; Thoracic aortic aneurysm; AngII; Angiotensin II; AT1r; AngII type I receptor; BMD; Bone mineral density; DCM; Dilated cardiomyopathy; ECM; Extracellular m

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Aberrant RNA translation in fragile X syndrome: From FMRP mechanisms to emerging therapeutic strategies

Keywords: Fragile X syndrome; mRNA translation; mRNA localization; RNA binding protein; Dendritic spine; iPSC;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

GABA function may be related to the impairment of learning and memory caused by systemic prenatal hypoxia-ischemia

Keywords: BSA; bovine serum albumin; CA; Ammon's horn; DG; dentate gyrus; EAAT; excitatory amino acid transporter; GABA; γ-aminobutyric acid; GAD; glutamic acid decarboxylase; HI; hypoxia-ischemia; HIE; hypoxic-ischemic encephalopathy; HRP; horseradish peroxidas

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold

Keywords: Biomimetic materials; Liver stem cells; Bioengineering; Organogenesis; iPSC; induced pluripotent stem cell; IH; iPSC derived hepatic progenitors; FDA; food and drug administration; TGFβ; transforming growth factor beta; 3D; three-dimensional; ICC; invert

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Differential distribution and function of GABABRs in somato-dendritic and axonal compartments of principal cells and interneurons in cortical circuits

Keywords: Dendritic inhibition; Presynaptic inhibition; Network activity; Electron microscopy; Synaptic plasticity; Ion channels; BC; basket cell; CA; cornu ammonis; CaMKII; Ca2+/calmodulin-dependent protein kinase II; cAMP; cyclic adenosine monophosphate; Cav chan

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Examining the effects of alcohol on GABAA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells

Keywords: Alcohol-use disorder; iPSC; Induced pluripotent stem cells; GABA receptor; Gene expression; Electrophysiology;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

3D human brain cell models: New frontiers in disease understanding and drug discovery for neurodegenerative diseases

Keywords: 3D culture; iPSC; Organoid; Co-culture; Microfluidics; Neurodegenerative diseases;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Biotechnology Challenges to In Vitro Maturation of Hepatic Stem Cells

Keywords: Liver Development; Differentiation; Hepatocyte; Culture; CRISPR; clustered regularly interspaced short palindromic repeats; CYP; cytochrome P450; 3D; 3-dimensional; DNMTi; DNA methylation inhibitor; ECM; extracellular matrix; ESC; embryonic stem cell; ES-

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Human-based systems: Mechanistic NASH modelling just around the corner?

Keywords: Elafibranor (PubChem CID: 9864881); Obeticholic acid (PubChem CID: 447715); Pioglitazone (PubChem CID: 4829); Rosiglitazone (PubChem CID: 77999); Fenofibrate (PubChem CID: 3339); Serine (PubChem CID: 5951); ACC1; acetyl-coenzyme A carboxylase 1; AdipoR; a

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices

Keywords: BOLD; blood oxygenation level dependent; fMRI; functional magnetic resonance imaging; GABA; γ-aminobutyric acid; IPSC; inhibitory post synaptic current; MDD; major depressive disorder; serotonin; 5-HT; SNRI; serotonin norepinephrine reuptake inhibitor; S

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model

Keywords: AKT; ATXN1: ataxin-1 protein; iPSC; induced pluripotent stem cell; MSK1/2; mitogen- and stress-activated kinases 1 and 2; PKA; cyclic AMP-dependent protein kinase; SCA1; Spinocerebellar ataxia type 1; SCA1; Purkinje cells; Ataxia; Phosphorylation; ATXN1-S

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines

Keywords: ACN; acetonitrile; BCA; bicinchoninic acid; DMSO; dimethyl sulfoxide; ESI; electrospray ionization; HPLC; high pressure liquid chromatography; iPSC; induced pluripotent stem cell; LDA; low density array; MS; mass spectrometry; P450; cytochrome P450; PCA;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell

Keywords: NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

Keywords: 5-HT; 5-hydroxytryptamine; Aβ; β-amyloid; ABCA8; ATP binding cassette subfamily A member 8; AD; Alzheimer's disease; ADP; adenosine diphosphate; AGD; argyrophilic grain disease; ALS; amyotrophic lateral sclerosis; AMBRA-1; autophagy and beclin 1 regul

دانلود رایگان متن کامل مقاله ISI 131 صفحه سال انتشار : 2018 سفارش ترجمه

Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells

Keywords: Spinal muscular atrophy; HDAC inhibitor; iPSC; Neurons; Cyclic peptides;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals

Keywords: Zika virus; iPSC; Antivirals; Neuronal cells;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Lysophosphatidic acid signaling regulates the KLF9-PPARγ axis in human induced pluripotent stem cell-derived neurons

Keywords: Induced pluripotent stem cells; Kruppel-like factor 9; Lysophosphatidic acid; Peroxisome proliferator-activated receptor gamma; iPSC; induced pluripotent stem cell; KLF9; Kruppel-like factor 9; LPA; lysophosphatidic acid; PPARγ; peroxisome proliferator-a

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

New genes for accurate normalization of qRT-PCR results in study of iPS and iPS-derived cells

Keywords: ACTb; actin beta; AFS; amniotic fluid stem cells; B2M; beta-2-microglobulin; bFGF; basic fibroblast growth factor; C1orf43; chromosome 1 open reading frame 43; CHMP2A; charged multivesicular body protein 2A; EMC7; ER membrane protein complex subunit 7; ES

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Modelling urea-cycle disorder citrullinemia type 1 with disease-specific iPSCs

Keywords: Argininosuccinate synthetase; Citrullinemia type 1; iPSC; Hepatocyte; l-arginine; Urea cycle disorder;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Generation of LIF-independent induced pluripotent stem cells from canine fetal fibroblasts

Keywords: iPSC; Canine; Stem cells; Pluripotency; Cellular reprogramming;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival

Keywords: Hippo pathway; Reprogramming; iPSC; Mst1; Cell proliferation; iPSC; induced pluripotent stem cells; Mst1; mammalian sterile-20 like kinase 1; Oct4; octamer-binding transcription factor 4; Sox2; sex determining region Y box 2; Klf 4; kruppel-like factor 4;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Transactivator protein: An alternative for delivery of recombinant proteins for safer reprogramming of induced Pluripotent Stem Cell

Keywords: TAT protein; iPSC; Reprogramming somatic cell; Protein transduction;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion

Keywords: FGA; full growth area; RGA; restricted growth area; iPSC; induced pluripotent stem cells; iPS; Growth arrest; pH; Glucose; Lactate; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced human somatic cell reprogramming efficiency by fusion of the MYC transactivation domain and OCT4

Keywords: OCT4; MYC; Fusion protein; Reprogramming; Transactivation domain; Induced pluripotent stem cells; AP; Alkaline Phosphatase; EB; Embryoid Body; ESC; embryonic stem cell; DBD; DNA-binding domain; HNFK; human neonatal foreskin keratinocyte; HUC-MSC; Human um

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Atypical dopamine transporter inhibitors R-modafinil and JHW 007 differentially affect D2 autoreceptor neurotransmission and the firing rate of midbrain dopamine neurons

Keywords: Dopamine neuron; Dopamine transporter; Cocaine; D2 autoreceptor; Mouse; Substantia nigra; Ventral tegmental area; Neurotransmission; Firing; DAT; dopamine transporter; DA; dopamine; SNc; substantia nigra pars compacta; VTA; ventral tegmental area; IPSC; i

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Human neural progenitors derived from integration-free iPSCs for SCI therapy

Keywords: iPSC; Spinal cord injury; Neural repair; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-29 impairs the early phase of reprogramming process by targeting active DNA demethylation enzymes and Wnt signaling

Keywords: microRNA; miR; OKS.dT; hOCT4-hKLF4-hSOX2-dTom; OKSM.dT; hOCT4-hKLF4-hSOX2-hC-MYC-dTom; MEF; mouse embryonic fibroblasts; iPSC; induced pluripotent stem cells; ESC; embryonic stem cells; shRNA; short-hairpin RNA; siRNA; small interfering RNA; OG2; Oct4 pro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه