دانلود مقالات ISI درباره Ipsc + ترجمه فارسی

Methylene blue inhibits GABAA receptors by interaction with GABA binding site

Keywords: Recombinant receptors; Memory enhancing; Hippocampus; IPSC; GABA (PubChem CID:119); Methylene blue (PubChem CID: 6099); Muscimol (PubChem CID:4266); Tetrodotoxin (TTX) (PubChem CID: 11174599); 6-cyano-7-nitroquinoxaline-2; 3-dione (CNQX) (PubChem CID: 372

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models

Keywords: CPVT; MCU; MiCUp; mitochondria; RyR2; VDAC2; CPVT; catecholaminergic polymorphic ventricular tachycardia; epi/caff; epinephrine/caffeine; iPSC; induced pluripotent stem cell; ISO; isoproterenol; MCU; mitochondrial calcium uniporter; MiCUp; mitochondrial c

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperAlterations in hypoglossal motor neurons due to GAD67 and VGAT deficiency in mice

Keywords: E; embryonic day; EPSC; excitatory postsynaptic current; GAD67; glutamate decarboxylase 67; IPSC; inhibitory postsynaptic current; MN; motor neuron; VGAT; vesicular inhibitory amino acid transporter; WT; wild-type; Motor neuron; Brainstem; Synaptic curren

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnenolone does not interfere with the effects of cannabinoids on synaptic transmission in the cerebellum and the nucleus accumbens

Keywords: ACSF; artificial cerebrospinal fluid; IPSC; inhibitory postsynaptic current; EPSC; excitatory postsynaptic current; PRE; initial reference period; PREG; pregnenolone; SOL; solvent; THDOC; tetrahydrodeoxycorticosterone; CB1 cannabinoid receptor; Endocannab

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors

Keywords: GABAergic; IPSC; Tonic inhibition; Synaptic inhibition; TB-21007; MRK-016; α5IA; L-655708; GABAAR; GABA type-A receptor; IPSC; inhibitory postsynaptic current; DMEM-FBS; Dulbecco's Modified Eagles Medium supplemented with 10% fetal bovine serum; TB-21007

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia

Keywords: Mitochondrial ATP; Cardiomyocytes; Hypertrophy; Hypoxia; Phenotypic screening; ATP; adenosine triphosphate; BNP; brain natriuretic peptide; CsA; cyclosporin A; ET-1; endothelin 1; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; FPKM; fragment

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

PARP, transcription and chromatin modeling

Keywords: ABCA1; ATP-binding cassette transporter A1; ADP-ribosylation; adenosine diphosphate ribosylation; ALC1; amplified in-liver-cancer 1; AR; androgen receptor; ARH3; ADP-ribosylhydrolase 3; ART; ADP-ribosyl transferase; ASF/SF2; alternative splicing factor/sp

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Loss of dopamine D1 receptors and diminished D1/5 receptor-mediated ERK phosphorylation in the periaqueductal gray after spinal cord lesion

Keywords: DRM; detergent-resistant membranes; DSM; detergent-soluble membranes; ERK1,2; extracellular signal-regulated protein kinases 1 and 2; pERK1,2; phosphorylated ERK 1 and 2; i.p.; intraperitoneal; IPSC; inhibitory post-synaptic potential; PAG; periaqueductal

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa

Keywords: Induced pluripotent stem cells; Retinitis pigmentosa; TRNT 1; Retinal organoids; Autophagy; Oxidative stress; RP; Retinitis pigmentosa; TRNT1; tRNA Nucleotidyl Transferase, CCA-Adding 1; iPSC; induced pluripotent stem cells; CSA; congenital sideroblastic

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Evidence for M2 muscarinic receptor modulation of axon terminals and dendrites in the rodent basolateral amygdala: An ultrastructural and electrophysiological analysis

Keywords: cholinergic; electron microscopy; immunohistochemistry; whole-cell recording; IPSC;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration

Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose; AD; Alzheimer's disease; CBD; Corticobasal Degeneration; CSF; Cerebrospinal Fluid; DHE; Dihydroethidium; ETC; Electron Transport Chain; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)pheny

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

α4β2∗ nicotinic receptors stimulate GABA release onto fast-spiking cells in layer V of mouse prefrontal (Fr2) cortex

Keywords: 5-IA; 5-iodo-3-[2(S)-azetidinylmethoxy]pyridine; ACh; acetylcholine; ADNFLE; autosomal dominant nocturnal frontal lobe epilepsy; AHP; after-hyperpolarization; AP; action potential; AP5; d(−)-2-amino-5-phosphono-pentanoic acid; BSA; bovine serum albumin;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome-derived neural precursor cells

Keywords: MeCP2; L1CAM; RTT syndrome; iPSCs; Neuritogenesis; RTT; Rett Syndrome; MeCP2; methyl-CpG-binding protein-2; iPSC; induced pluripotent stem cell; RTT NPC; RTT iPSC-derived neural precursorcell; TRE; tetracycline response element; CAG; chicken beta-actin pr

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

(Re-)programming of subtype specific cardiomyocytes

Keywords: ADSC; adipose tissue-derived mesenchymal stem cell; Alcam; activated leukocyte cell adhesion molecule; AMI; acute myocardial infarction; ANF; natriuretic factor; AP; action potential; ASC; adult stem cell; AV; atrioventricular; AVB; atrioventricular bundl

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Transflammation: Innate immune signaling in nuclear reprogramming

Keywords: PRR; pattern recognition receptor; TLR; toll-like receptor; RIG-1; retinoid acid-inducible gene I; RLR; RIG-1-like receptor; ROS; reactive oxygen species; RNS; reactive nitrogen species; iPSC; induced pluripotent stem cell; ESC; embryonic stem cell; MHC;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

An impedance-based approach using human iPSC-derived cardiomyocytes significantly improves in vitro prediction of in vivo cardiotox liabilities

Keywords: Cardiotoxicity; Impedance; Cardiomyocytes; iPSC; In vitro; Drug discovery; CiPA; comprehensive in vitro proarrhythmia assay; hIPSC-CMs; human induced pluripotent stem cell cardiomyocytes; HDAC; histone deacetylase inhibitors;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Chimeric antigen receptor-engineered natural killer and natural killer T cells for cancer immunotherapy

Keywords: aAPC; artificial antigen-presenting cells; αGalCer; α-galactosylceramide; ACT; adoptive cell transfer; ADCC; antibody-dependent cell-mediated cytotoxicity; ALL; Acute Lymphoblastic Leukemia; AML; acute lymphoid leukemia; CAR; chimeric antigen receptor;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

3D in vitro models of liver fibrosis

Keywords: HSCs; hepatic stellate cells; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aminotransferase; CBDL; common biled duct ligation; DAMPs; damage associated molecular patterns; DCM; decellularized matrix; DILI; drug-induced liver injury; ECM; extra

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Modeling schizophrenia pathogenesis using patient-derived induced pluripotent stem cells (iPSCs)

Keywords: Schizophrenia; iPSC; Neural progenitor cell; Differentiation;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

Keywords: Neural induction; Neural progenitor cells; hiPSC; Electron microscopy; Patch clamp; 2D-3D neural induction; AD; Alzheimer's disease; AQP4; Aquaporin 4; ASD; Autism spectrum disorder; bFGF; Basic Fibroblast Growth Factor; CNS; Central Nervous System; D; Da

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Architecture in 3D cell culture: An essential feature for in vitro toxicology

Keywords: 2D; two-dimensional; 3D; three-dimensional; ECM; extracellular matrix; EHS; Engelbreth-Holm-Swarm; iPSC; induced-pluritpotent stem cell; PDMS; polydimethyl siloxane; PEL; permissible exposure level; Polarity; Cell nucleus; Organ-on-a-chip; Tight junction;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Transient exposure to proteins SOX2, Oct-4, and NANOG immortalizes exhausted tumor-infiltrating CTLs

Keywords: ACT; TILs; TICTLs; STICTLs; SON; Nuclear delivery; 3SI; 3-signal activation by antigen, costimulation, and third signal cytokine; ACT; Adoptive Cell Transfer Therapy; CTL; Cytotoxic T Lymphocyte; DN; Double negative T cells; DP; Double positive T cells; i

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

The CCR4-NOT deadenylase activity contributes to generation of induced pluripotent stem cells

Keywords: The CCR4-NOT complex; iPSC; p21; Eomes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Efficient production of platelets from mouse embryonic stem cells by enforced expression of Gata2 in late hemogenic endothelial cells

Keywords: ES cells; In vitro differentiation; Megakaryocytes; Platelets; Gata2; ESC; embryonic stem cell; Mk; megakaryocyte; iPSC; induced pluripotent stem cell; HSC; hematopoietic stem cell; HEC; hemogenic endothelial cell; AGM; aorta-gonad-mesonephros; dpc; post

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Glycine blocks long-term potentiation of GABAergic synapses in the ventral tegmental area

Keywords: aCSF; artificial cerebrospinal fluid; DNQX; 6,7-dinitroquinoxaline-2,3-dione; eIPSC; evoked inhibitory postsynaptic current; GABA; gamma-aminobutyric acid; GABAAR; GABAA receptor; GlyR; glycine receptor; GLYTs; glycine transporters; HFS; high-frequency st

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Controlling stem cell behavior with decellularized extracellular matrix scaffolds

Keywords: ASC; adipose derived stem cell; ECM; extracellular matrix; EDC; 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide; ESC; embryonic stem cell; hASC; human adipose derived stem cell; hESC; human embryonic stem cell; hMSC; human mesenchymal stem cell; iPSC; indu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Transgenic Mouse Models Transferred into the Test Tube: New Perspectives for Developmental Toxicity Testing In Vitro?

Keywords: teratogens; transgenic mouse models; in vitro testing; ESC; iPSC;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Differentiation of human pluripotent stem cells into Medial Ganglionic Eminence vs. Caudal Ganglionic Eminence cells

Keywords: PSCs; pluripotent stem cells; hPSCs; human pluripotent stem cells; MGE; Medial Ganglionic Eminence; CGE; Caudal Ganglionic Eminence; hiPSCs; human induced pluripotent stem cells; iPSC; induced pluripotent stem cell; ESCs; embryonic stem cells; E8; Essenti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13

Keywords: AMD; age-related macular degeneration; bp; base pairs; DHS; DNase 1 hypersensitivity site; iPSC; induced pluripotent stem cell; NCMD; North Carolina macular dystrophy; 3D; 3-dimensional;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Nicotinic acetylcholine receptor-mediated GABAergic inputs to cholinergic interneurons in the striosomes and the matrix compartments of the mouse striatum

Keywords: Acetylcholine; Nicotinic; Cholinergic interneuron; Striosome; Matrix; ABT-418; 3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; ACh; acetylcholine; AChE; acetylcholinesterase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Active DNA demethylation by DNA repair: Facts and uncertainties

Keywords: 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5hmU; 5-hydroxymethyluracil; 5fC; 5-formylcytosine; 5caC; 5-carboxycytosine; AID; activation-induced deaminase; APE1; apurinic/apyrimidinic endonuclease 1; APOBEC; apolipoprotein B mRNA editing enzyme,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Photoreceptor Progenitor mRNA Analysis Reveals Exon Skipping Resulting from the ABCA4 c.5461-10T→C Mutation in Stargardt Disease

Keywords: BCVA; best-corrected visual acuity; CRD; cone-rod dystrophy; DAPI; 4′,6-diamidino-2-phenylindole; DMEM/F12; Dulbecco's Modified Eagle Medium: Nutrient Mixture F-12; dNTPs; deoxynucleotide triphosphates; ERG; electroretinography; iPSC; induced pluripot

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance

Keywords: AD; Alzheimer's disease; oAβ; soluble Aβ oligomers; AP5; dl-2-amino-5-phosphonopentanoic acid; fEPSP; field excitatory postsynaptic potentials; E-S; EPSP-spike; GT; glutamate transporter; IPSC; inhibitory postsynaptic currents; sEPSC; spontaneous ex

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Streptozotocin inhibits synaptic transmission and edaravone attenuates streptozotocin-induced electrophysiological changes in CA1 pyramidal neurons of rat hippocampal slices

Keywords: Streptozotocin; Edaravone; Pyramidal neuron; Slice patch clamp; EPSC; IPSC;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Cytoskeletal dynamics during in vitro neurogenesis of induced pluripotent stem cells (iPSCs)

Keywords: iPSC; induced pluripotent stem cells; ESC; embryonic stem cell; MT; microtubules; AF; actin filaments; IF; intermediate filaments; ALS; amyotrophic lateral sclerosis; HD; Huntington's disease; PD; Parkinson's disease; Neurogenesis; Neuritogenesis; Cytoske

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Wnt signaling pathway improves central inhibitory synaptic transmission in a mouse model of Duchenne muscular dystrophy

Keywords: ACSF; artificial cerebrospinal fluid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ANDRO; andrographolide; APV; 2-amino-5-phosphonovaleric acid; AraC; 1-β-D-arabinofuranosylcytosine; CaMKII; calmodulin-dependent protein kinase II

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Exome and genome sequencing for inborn errors of immunity

Keywords: Next-generation sequencing; whole-exome sequencing; whole-genome sequencing; targeted sequencing; primary immunodeficiency; AD; Autosomal dominant; AF; Allele frequency; AR; Autosomal recessive; CADD; Combined annotation-dependent depletion; CID; Combined

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency

Keywords: macrophages; PAP; iPSC; disease modeling; hematopoiesis

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

The Promise and Challenge of Induced Pluripotent Stem Cells for Cardiovascular Applications

Keywords: cardiac regeneration; disease modeling; drug discovery; induced pluripotent stem cells; ESC; embryonic stem cell(s); iCM; induced pluripotent stem cell-derived cardiomyocyte(s); iEC; induced pluripotent stem cell-derived endothelial cell(s); iPSC; i

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells

Keywords: Gene delivery; Graphene oxide-polyethylenimine complex; Footprint-free transgene-free; Integration-free; Human induced pluripotent stem cells; iPSC; RNA delivery;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Patient-specific hiPSC bioprocessing for drug screening: Bioprocess economics and optimisation

Keywords: COG; cost of goods; CTS; CompacT SelecTTM automated cell culture machine; FCI; fixed capital investment; hPSC; human pluripotent stem cell; HTS; high throughput screening; iPSC; induced pluripotent stem cell; PCA; patch-clamp analysis; NCE; novel chemical

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming

Keywords: Oct4; reprogramming; histone modification; iPSC

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportActivation of 5-hyrdoxytryptamine 7 receptors within the rat nucleus tractus solitarii modulates synaptic properties

Keywords: Serotonin receptors; Autonomic nervous system; Patch clamp; EPSC; IPSC; Respiration;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes

Keywords: Neurotoxicity; Drug screening; iPSC; Neural stem cells; Neurons; Astrocytes; Lineage-specific reporter lines

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

TDP-43/FUS in motor neuron disease: Complexity and challenges

Keywords: AD; Alzheimer's disease; Ago2; Argonaute 2; ALS; Amyotrophic lateral sclerosis; ALS/PD; amyotrophic lateral sclerosis and Parkinsonism-dementia complex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF3; activating transcription factor 3

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2016 سفارش ترجمه

A temperature-sensitive, self-adhesive hydrogel to deliver iPSC-derived cardiomyocytes for heart repair

Keywords: Polymer hydrogel; Cell delivery; iPSC; Cardiomyocyte; Heart repair;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

“The future of in vitro toxicology”

Keywords: Omics; Stem cells; 3R; iPSC;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Potentiation of tonic GABAergic inhibition by activation of postsynaptic kainate receptors

Keywords: AP-5; D-(−)-2-amino-5-phosphonopentanoic acid; eGABAAR; extrasynaptic GABAA receptor; EGTA; ethylene glycol tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IPSC; stimulus-evoked inhibitory postsynaptic current; KA; Kainic ac

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Systems biology of IL-6, IL-12 family cytokines

Keywords: Systems biology; Mathematical modeling; IL-6-type cytokines; Quantitative analyses; Epo; erythropoietin; gp; glycoprotein; hESC; human embryonic stem cells; EGF; epidermal growth factor; ERK; extracellular signal regulated kinase; HGF; hepatocyte growth f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

piggyBac-ing models and new therapeutic strategies

Keywords: piggyBac; transposon; iPSC; transgenesis; cell therapy; immunotherapy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه