دانلود مقالات ISI درباره Ipsc + ترجمه فارسی

Evaluation of established human iPSC-derived neurons to model neurodegenerative diseases

Keywords: HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; iPSC; induced pluripotent stem cells; disease modeling; neurodegeneration; hiPSC; GABAergic neuron;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportEffects of prostaglandin E2 on synaptic transmission in the rat spinal trigeminal subnucleus caudalis

Keywords: COX2; cyclooxygenase 2; EPSC; excitatory postsynaptic current; IPSC; inhibitory postsynaptic current; PGE2; prostaglandin E2; Vc; spinal trigeminal subnucleus caudalis; Vsp; spinal trigeminal nucleus; Prostaglandin E2; Synaptic transmission; Spinal trigem

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The impact of NMDA receptor hypofunction on GABAergic neurons in the pathophysiology of schizophrenia

Keywords: BOLD; blood-oxygen-level dependent; CaM; calmodulin; CaMK; Ca2 +/CaM dependent protein kinase; DMN; default mode network; DAN; dorsal attentional network; EPSC; excitatory postsynaptic current; GAD67; glutamic acid decarboxylase 67; IPSC; inhibitory post

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Induced pluripotent stem cells from ALS patients for disease modeling

Keywords: Stem cell; iPSC; Motor neuron; Astrocyte; Non-cell autonomous; Human

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Point-, line-, and plane-shaped cellular constructs for 3D tissue assembly

Keywords: 3D; three-dimensional; 2D; two-dimensional; iPSC; induced pluripotent stem cell; ESC; embryonic stem cell; ECM; extracellular matrix; CV; coefficient of variation; PEG; poly(ethylene glycol); PVA; poly(vinyl alcohol); AFFD; axisymmetric flow-focusing devi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis

Keywords: ESC; embryonic stem cell; iPSC; induced pluripotent stem cell; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; FoxA2; forkhead box A2; Sox17; sex determining region Y box 17; Oct-4; octamer-binding transcription factor 4; CDH1; E-cadherin-1; IGFR; i

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9

Keywords: 3-BrPA; 3 bromopyruvate; AOP; adverse outcome pathway; ARF4; ADP-ribosylation factor 4; BFA; brefeldin A; BT; 1,2,4-benzenetriol; CML; chronic myeloid leukemia; COSMID; CRISPR off-target sites with mismatches, insertions, and deletions; CRISPR-Cas9; clust

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Quantitative in vitro to in vivo extrapolation of tissues toxicity

Keywords: ADME; absorption, distribution, metabolism, and excretion; ARE; antioxidant responses elements; BBB; blood brain barrier; CsA; cyclosporine A; CYP; cytochrome P450; EPA; Environmental Protection Agency; GCL; glutamate cysteine ligase; GCLC; glutamate cyst

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Differentiation of human pluripotent stem cells into β-cells: Potential and challenges

Keywords: stem cell therapy; diabetes; type 1 diabetes; iPSC; hESC

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging

Keywords: Amyotrophic lateral sclerosis; Frontotemporal dementia; Fused in sarcoma; Translated in sarcoma; RNA granules; Stress granules; Aggregate prone disease; Disease spreading; Cortical neurodegeneration; Motor neuron disease; FUS-FTLD; iPSC; Human cell models

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology

Keywords: AAV; adeno-associated virus; AON; antisense oligonucleotide; bp; base pair; Ca2+;  calcium; CaMKII; Ca2+/calmodulin-dependent kinase II; Chr; chromosome; CK2; casein kinase 2; CMH4; hypertrophic cardiomyopathy, locus 4; cMyBP-C; cardiac myosin-binding pr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma glucocorticoids differentially modulate phasic and tonic GABA inhibition during early postnatal development in rat spinal lamina II

Keywords: 3α5αNS; 3α5α-reduced neurosteroids; ACSF; artificial cerebrospinal fluid; BIC; bicuculline; CORT; corticosterone; FIN; finasteride; GABAAR; GABAA receptor; FIS; Fischer; GABA; γ-aminobutyric acid; GBZ; gabazine; GC; glucocorticoids; HPA; hypothalamic

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs

Keywords: PD; Pompe disease; GSDII; glycogen storage disease type II; GAA; acid-α-glycosidase; LSD; lysosomal storage disease; ERT; enzyme replacement therapy; iPSC; induced pluripotent stem cell; PAS; Periodic-acid-Schiff; ALP; alkaline phosphates; TEM; transmiss

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency

Keywords: Carnitine palmitoyltransferase II deficiency; iPSC; Disease modeling; Rhabdomyolysis; Bezafibrate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Associate editor: O. BinahInduced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing

Keywords: iPSC; Drug screening; High-throughput screening; QT prolongation; Drug toxicity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Widespread genome transcription: New possibilities for RNA therapies

Keywords: Aβ; amyloid beta; AGO; argonaute; AON; antisense oligonucleotide; AS RNA; antisense RNA; ATL; adult T-cell leukemia; EBOV; Ebola virus; eRNA; enhancer RNA; ES; embryonic stem; HBZ; HTLV-1 basic leucine zipper factor; HTLV-1; human T-cell leukemia virus t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: Direct evidence of functional Ca2+-induced Ca2+ release

Keywords: AP; action potential; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CICR; Ca2+-induced Ca2+ release; CM; cardiomyocyte; EC; excitation-contraction; FDHM; full duration at half maximum; FWHM; full width at half maximum; hESC; human embryonic stem cell;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Kisspeptin-10 potentiates miniature excitatory postsynaptic currents in the rat supraoptic nucleus

Keywords: Kisspeptin; EPSC; IPSC; Slice patch clamp; Supraoptic nucleus;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus

Keywords: AdR; adrenergic receptor; BDNF; Brain-derived neurotrophic factor; Ct; cycle threshold; DAT; dopamine transporter; DRD2; dopamine D2 receptor; DRD4; dopamine D4 receptor; EDTA; ethylenediaminetetraacetic acid; EPSC; excitatory postsynaptic current; FC; fr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Enhanced excitatory synaptic network activity following transient group I metabotropic glutamate activation

Keywords: ACPD; (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid; AHP; afterhyperpolarizing; 4-AP; 4-aminopyridine; APV; d,l-2-amino-5-phosphonovaleric acid; ASCF; artificial cerebrospinal fluid; CNQX; 6-cyano-7-nitoquinoxaline-2,3-dione; DHPG; (S)-3,5-dihydroxyph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid enhances Oct4 promoter activity through PI3K/Akt/mTOR pathway activated nuclear receptors

Keywords: Muscle; Oct4; Nuclear receptor; iPSC; VPA; Akt;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Extracellular pH modulates GABAergic neurotransmission in rat hypothalamus

Keywords: ACSF; artificial cerebral-spinal fluid; ANOVA; analysis of variance; ASICs; acid-sensing ion channels; EGTA; ethylene glycol tetraacetic acid, HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IPSC; inhibitory postsynaptic current; MES; 2-ethanes

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

In vitro and in vivo differentiation of induced pluripotent stem cells into male germ cells

Keywords: iPSC; induced pluripotent stem cell; ESC; embryonic stem cell; EB; embryoid body; PGC; primordial germ cell; GSC; germ stem cell; Induced pluripotent stem cell (iPSC); Germ stem cell (GSC); Spermatogenesis; Niche; Ectopic reconstitution of seminiferous tu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons

Keywords: aCSF; artificial cerebrospinal fluid; AMPA; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; AMPAR; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid receptor; D-APV; aminophosphonopentanoic acid; HESC; human embryonic stem cell; HPSC; hum

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Electronic “expression” of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells

Keywords: AP; action potential; APD; action potential duration; DAD; delayed afterdepolarization; dV/dtmax; maximum rate of change of voltage with time; EAD; early afterdepolarization; h-iPSC; human-induced pluripotent stem cell; ICa; calcium current; If; pacemaker

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity

Keywords: iPSC; induced pluripotent stem cell; BMC; benchmark concentration; DMSO; dimethyl sulfoxide; AUC; area under the curve; EC50; effective concentration at 50% of the maximum response; iPSC; Calcium flux; Cardiotoxicity; hERG; Phenotypic screening; Predictiv

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

DNA double‐strand break response in stem cells: Mechanisms to maintain genomic integrity

Keywords: ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; BRCA1; breast cancer type 1 susceptibility protein; CtBP; C-terminal binding protein; CtIP; CTBP interacting protein; DDR; DNA damage response; DNA-PK; DNA-dependent

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2L and D2S

Keywords: AAV; adeno-associated virus; BSA; bovine serum albumin; D2L; D2 receptor long form; D2S; receptor short form; DARPP-32; Dopamine- and cyclic AMP-regulated phosphoprotein of about 32 kD; Drd2−/−; D2 receptor null mutant; Drd2ex6−/ex6−; D2L receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Transplantation of induced pluripotent stem cells without C-Myc attenuates retinal ischemia and reperfusion injury in rats

Keywords: oxidative stress; ischemia-reperfusion injury; induced pluripotent stem cells; paracrine; c-Myc; iPSC; induced pluropotent stem cells; ERG; electroretinogram; TUNEL; TdT-dUTP terminal nick-end labeling; 8-OHdG; 8-hydroxy-2′-deoxyguanosine; BDNF; brain-d

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Mesenchymal stem cell secretome and regenerative therapy after cancer

Keywords: Mesenchymal stem/stromal cells; Regenerative therapy after cancer; Cancer recurrence; Tumor-initiating cells; ASC; adipose-derived stem/stromal cells; BA; breast adipose; BM; bone marrow; CCL; chemokine C-C motif ligand; CSC; cancer stem cells; CXCL; Câ

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Reactive oxygen species enhance excitatory synaptic transmission in rat spinal dorsal horn neurons by activating TRPA1 and TRPV1 channels

Keywords: AITC; allyl isothiocyanate; AMPA; α-amino-3-hydroxy-5-methyl-4-isozazole propionate; CNP; central neuropathic pain; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; DRG; dorsal root ganglion; EPSC; excitatory postsynaptic currents; IPSC; inhibitory postsynapt

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Induction of retinal ganglion-like cells from fibroblasts by adenoviral gene delivery

Keywords: AB2N-iNs; AB2N-induced neurons; EGTA; ethylene glycol tetraacetic acid; ESCs; embryonic stem cells; ETF; ear tip fibroblast; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; iPSC; induced pluripotent stem cell; iRG-like cell; induced retinal gan

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Application of advanced validation concepts to oxide fuel performance codes: LIFE-4 fast-reactor and FRAPCON thermal-reactor fuel performance codes

Keywords: AISI; American Iron and Steel Institute; EBR-II; Experimental Breeder Reactor-II; FCAS; fuel column axial strain; FCHR; fuel central hole radius; FCMI; fuel cladding mechanical interaction; FCZR; fuel column zone radius; FEZR; fuel equiaxed zone radius; F

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice

Keywords: Acta1; α-skeletal actin gene or mRNA; Atp2a2; ATPase, Ca2 + transporting, cardiac mRNA; BPM; Beats per minute; cMyBP-C; Cardiac myosin-binding protein C; EC50; Half maximal effective concentration; EHT; Engineered heart tissue; EMD; EMD 57033; HCM; Hype

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells

Keywords: ALS; amyotrophic lateral sclerosis; iPSC; induced pluripotent stem cells; TDP-43; TARDBP, TAR DNA binding protein; SOD1; superoxide dismutase 1; FTLD; fronto-temporal lobar degeneration; iPSC-MN; induced pluripotent stem cell-derived motor neurons; iPSC-C

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2013 سفارش ترجمه

Advances in cellular reprogramming: Moving toward a reprieve from immunogenicity

Keywords: Immunogenicity; iPSC; Reprogramming; Lineage conversion; Tumorigenicity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Clinical Therapy Using iPSCs: Hopes and Challenges

Keywords: iPSC; Regenerative medicine; Disease modeling; Immunogenicity; Tumorigenicity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Investigation of telomere length dynamics in induced pluripotent stem cells using quantitative fluorescence in situ hybridization

Keywords: Telomere; iPSC; Q-FISH; Chromosome; Karyotype analysis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Lack of interaction of endocannabinoids and 5-HT3 neurotransmission in associative fear circuits of the amygdala: Evidence from electrophysiological and behavioural experiments

Keywords: CB1; 5-HT3; Amygdala; Fear conditioning; Slice; IPSC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Materials Science and Tissue Engineering: Repairing the Heart

Keywords: bFGF; basic fibroblast growth factor; ECM; extracellular matrix; EHT; engineered heart tissue; ESC; embryonic stem cell; HA; hyaluronic acid; hESC; human embryonic stem cell; iPSC; induced pluripotent stem cell; LV; left ventricular; MeHA; methacrylated h

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

A novel role of miR-302/367 in reprogramming

Keywords: miRNAs; miR-302; miR-367; Embryonic stem cells; Embryonic-like stem cell; Stem cell reprogramming; iPSC; miRNA-mediated iPSC (mirPSC)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Disrupted GABAAR trafficking and synaptic inhibition in a mouse model of Huntington's disease

Keywords: Huntingtin; GABAA receptor; IPSC; KIF5; Microtubule; Trafficking;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Generating pluripotent stem cells: Differential epigenetic changes during cellular reprogramming

Keywords: iPSC; ntESC; ESC; pESC; Stem cell; Epigenetic; Differentiation; Reprogramming;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome

Keywords: Inhibitory system; GABAA receptor; GABAB receptor; Evoked inhibitory postsynaptic currents; IPSC; Potassium channels; Kir3.2 subunits; Dentate gyrus; Down syndrome

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Promotion of the induction of cell pluripotency through metabolic remodeling by thyroid hormone triiodothyronine-activated PI3K/AKT signal pathway

Keywords: T3; PI3K/AKT signal pathway; Induced pluripotent stem cell; iPSC; Reprogramming; Metabolic remodeling

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Calcium signaling in pluripotent stem cells

Keywords: Pluripotent stem cell; Human embryonic stem cell; Induced pluripotent stem cell; Calcium signaling; Receptor-induced calcium signal; Fluorescent calcium indicators; hESC; human embryonic stem cell; mESC; mouse embryonic stem cell; iPSC; induced pluripoten

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Purinergic modulation of the excitatory synaptic input onto rat striatal neurons

Keywords: Striatal medium spiny neurons; NMDA receptors; ATP; Adenosine; Presynaptic purinergic modulation; Postsynaptic purinergic modulation; ADA; adenosine deaminase; AMPA; (S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AP-5; d,l-2-amino-5-phosphonop

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

GABAergic signaling and connectivity on Purkinje cells are impaired in experimental autoimmune encephalomyelitis

Keywords: EAE; Multiple sclerosis; IPSC; Cerebellar interneurons; PC; Parvalbumin; IL1-beta; VGAT;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Hepatocyte-like cells differentiated from human induced pluripotent stem cells: Relevance to cellular therapies

Keywords: AFP; alpha fetoprotein; Alb; albumin; ATP5g1; mitochondrial F0 complex, subunit C1 (subunit 9), ATP synthase 5 subunit e; ATP8; ATP synthase 8; BAL; bioartificial liver; BMP4; bone morphogenetic protein 4; CYP; cytochrome P450; CYP2C19; CYP Family 2, Subf

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

The state of the art for pluripotent stem cells derivation in domestic ungulates

Keywords: Ungulates; Bovine; Ovine; Stem cells; ESC; iPSC;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه