دانلود مقالات ISI درباره Ipscs + ترجمه فارسی

Serotonin differentially modulates excitatory and inhibitory synaptic inputs to putative sleep-promoting neurons of the ventrolateral preoptic nucleus

Keywords: VLPO; Single-cell RT-PCR; Gal-GFP neurons; EPSCs; IPSCs; NREM; 5-HT; serotonin; 5-HTR; serotonergic receptor; Gal; galanin; mEPSC; miniature excitatory post-synaptic current; mIPSC; miniature inhibitory post-synaptic current; NA; noradrenaline; PSP; putat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewEngineering cell fate: Spotlight on cell-activation and signaling-directed lineage conversion

Keywords: iPSCs; Induced Pluripotent Stem Cells; MEFs; Mouse Embryonic Fibroblasts; CASD; Cell-Activation and Signaling-Directed; GRNs; Gene Regulatory Networks; TRN; Transcriptional Regulatory Network; PDGF; Platelet-derived growth factor; FLT3LG or Flt-3L; Flt3 l

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Low-frequency electrical stimulation enhances the effectiveness of phenobarbital on GABAergic currents in hippocampal slices of kindled rats

Keywords: ACSF; artificial cerebrospinal fluid; AD; afterdischarge; ADT; afterdischarge threshold; EGTA; ethylene glycol tetraacetic acid; eIPSC; evoked inhibitory post-synaptic current; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IPSCs; inhibitory p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Building brains in a dish: Prospects for growing cerebral organoids from stem cells

Keywords: dcx; doublecortex; ESCs; embryonic stem cells; IPCs; intermediate progenitor cells; iPSCs; induced pluripotent stem cells; ISVZ; inner subventricular zone; Ngn2; Neurogenin 2; oRG; outer radial glia; OSVZ; outer subventricular zone; PSCs; pluripotent stem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Advances in therapeutic CRISPR/Cas9 genome editing

Keywords: Cas9; CRISPR-associated protein 9; cccDNA; covalently closed circular DNA; CCR5; chemokine receptor 5; CFTR; cystic fibrosis transmembrane conductance regulator; CRISPRs; clustered regularly interspaced short palindromic repeats; crRNA; CRISPR RNA; Crygc;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Early GABAergic transmission defects in the external globus pallidus and rest/activity rhythm alteration in a mouse model of Huntington's disease

Keywords: ACSF; artificial cerebrospinal fluid; EGTA; ethylene glycol tetraacetic acid; FI; fragmentation index; GPe; external globus pallidus; HD; Huntington's disease; Hepes; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IPSCs; inhibitory post-synaptic cu

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of Src and forkhead box O1 signaling by induced pluripotent stem-cell therapy attenuates hyperoxia-augmented ventilator-induced diaphragm dysfunction

Keywords: ALI; acute lung injury; FoxO1; class O of forkhead box 1; iPSCs; induced pluripotent stem cells; iPSC-CM; induced pluripotent stem-cell-derived conditioned medium; LC3; light chain 3; MDA; malondialdehyde; MuRF-1; muscle ring finger-1; MV; mechanical ve

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting of the human F8 at the multicopy rDNA locus in Hemophilia a patient-derived iPSCs using TALENickases

Keywords: Hemophilia A; iPSCs; Ribosomal DNA; Multicopy; TALENickases;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

Antitumor dendritic cell-based vaccines: lessons from 20 years of clinical trials and future perspectives

Keywords: APCs; antigen-presenting cells; cDCs; classical DCs; CTLs; cytotoxic T cells; CTLA-4; cytotoxic T-lymphocyte-associated antigen 4; DC; dendritic cell; Dex; dendritic cell-derived exosomes; EMA; European Medicines Agency; FDA; Food and Drug Administratio

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Energy metabolism in neuronal/glial induction and in iPSC models of brain disorders

Keywords: Mitochondria; Metabolism; Neurons; Glia; Neural progenitors; Reprogramming; iPSCs; Mitochondrial disorders;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Modeling synaptogenesis in schizophrenia and autism using human iPSC derived neurons

Keywords: IPSCs; Neurodevelopmental disorders; Synapses; Glutamatergic neurons; Neural development;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Neurodevelopmental origins of bipolar disorder: iPSC models

Keywords: ASD; autism spectrum disorders; BA; Broadmann's area; BDNF; brain derived neurotrophic factor; BP; bipolar disorder; C; healthy controls; CNS; central nervous system; DLPFC; dorsolateral prefrontal cortex; hESCs; human embryonic stem cells; iNs; induced n

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2016 سفارش ترجمه

Rho-kinase signaling controls nucleocytoplasmic shuttling of class IIa Histone Deacetylase (HDAC7) and transcriptional activation of orphan nuclear receptor NR4A1

Keywords: ROCK; Rho kinase; OPHN1; Oligophrenin-1; HDAC7; Histone Deacetylase 7; MYPT1; myosin phosphatase subunit 1; MLCP; myosin light chain phosphatase; MLCK; myosin light chain kinase; NR4A1; nuclear receptor subfamily 4, group A, member 1; iPSCs; induced pluri

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Decrease in CA3 inhibitory network activity during Theiler's virus encephalitis

Keywords: Viral encephalitis; IPSCs; CA3; Mouse model; Mesial temporal sclerosis; Epilepsy;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Cerebal overinhibition could be the basis for the high prevalence of epilepsy in persons with Down syndrome

Keywords: DS; Down syndrome; E/I; excitatory and inhibitory; HAS21; trisomy of human chromosome 21; IS; infantile spasms; LOMEDS; late-onset myoclonic epilepsy in Down syndrome; iPSCs; induced pluripotent stem cells; GIRK2; G-protein-coupled inward rectifying potas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo

Keywords: Neurons; Somatic cells; Astrocytes; Trans-differentiation; Defined medium; bFGF; basic fibroblast growth factor; βMe; β-mercaptoethanol; BM-hMSCs; mesenchymal stem cells from human bone marrow; EGF; epidermal growth factor; ESCs; embryonic stem cells; G

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Role of the IL-1 receptor antagonist in ethanol-induced regulation of GABAergic transmission in the central amygdala

Keywords: Il1rn knockout mice; CeA; GABAA; IPSCs; Kineret;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Cocaine-seeking is associated with PKC-dependent reduction of excitatory signaling in accumbens shell D2 dopamine receptor-expressing neurons

Keywords: Striatum; Dopamine; Addiction; Self-administration; Relapse; Electrophysiology; EPSCs; IPSCs;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Snake neurotoxin α-bungarotoxin is an antagonist at native GABAA receptors

Keywords: GABA receptor; Nicotinic acetylcholine receptor; α-bungarotoxin; Dentate gyrus; Electrophysiology; Immunofluorescence; d-Tc; d-tubocurarine; GABAARs; γ-aminobutyric type-A receptors; α-Bgtx; α-bungarotoxin; nAChRs; nicotinic acetylcholine receptors; Î

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Fibroblast heterogeneity and its implications for engineering organotypic skin models in vitro

Keywords: Organotypic skin; Fibroblast heterogeneity; Wound healing; Skin models; Skin substitutes; Tissue engineering; 3D; three-dimensional; AdSCs; adipose-derived stem cells; AP-1; activated protein-1; Blimp1; B lymphocyte-induced maturation protein-1; BP; bullo

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells

Keywords: Cancer Stem Cells; Chemotherapy Drug Resistance; iPSCs; Tumor Progression; 5-aza; 5-azacytidine; 5-FU; 5-fluorourail; AFP; alpha-fetoprotein; AJCC; American Joint Committee on Cancer; ALB; albumin; ATOH8; atonal homolog 8; AP; alkaline phosphatase; ATRA;

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2015 سفارش ترجمه

A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons

Keywords: 3D culture; Self-assembling peptide; Alzheimer's disease; Mechanotransduction; iPSCs; Neuron;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Role of Oct4 in the early embryo development

Keywords: Oct4; Oct4B; Totipotency; Pluripotency; Embryo; Development; ICM; Inner cell mass; ESCs; Embryonic stem cells; TE; Trophectoderm; PGCs; Primordial germ cells; Pit-Oct-Unc; POU; POUS; POU-specific; POUHD; Homeodomain; N-domain; N-terminal domain; C-domain;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Allogeneic pluripotent stem cells suppress airway inflammation in murine model of acute asthma

Keywords: Acute asthma murine model; BALB/c; ESCs; iPSCs; OVA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

GABAergic synaptic transmission onto striatal cholinergic interneurons in dopamine D2 receptor knock-out mice

Keywords: ω-Aga-TK; ω-agatoxin TK; ω-CgTX; ω-conotoxin GVIA; ACh; acetylcholine; CNQX; 6-cyano-7-nitroquinoxalline-2,3-dione; D2R; D2 receptor; D-AP5; D-(−)-2-amino-5-phosphonopentanoic acid; DA; dopamine; EGTA; ethylene glycol tetraacetic acid; HEPES; 2-[4-(

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Differentiation of iPSCs into insulin-producing cells via adenoviral transfection of PDX-1, NeuroD1 and MafA

Keywords: Insulin; β Cell; iPSCs; Transplantation; Transgenes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleLiver X receptor α (LXRα/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4α

Keywords: NR1H3; liver X receptor α; HNF; hepatocyte nuclear factor; MSCs; mesenchymal stem cells; ESCs; embryonic stem cells; iPSCs; induced pluripotent stem cells; RT; reverse-transcription; ChIP; chromatin immunoprecipitation; Hepatogenesis; LXRα/NR1H3; HNF4A;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Enhanced excitatory synaptic network activity following transient group I metabotropic glutamate activation

Keywords: ACPD; (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid; AHP; afterhyperpolarizing; 4-AP; 4-aminopyridine; APV; d,l-2-amino-5-phosphonovaleric acid; ASCF; artificial cerebrospinal fluid; CNQX; 6-cyano-7-nitoquinoxaline-2,3-dione; DHPG; (S)-3,5-dihydroxyph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Natriorexigenic effect of DAMGO is decreased by blocking AT1 receptors in the central nucleus of the amygdala

Keywords: μ-ORs; μ-opioid receptors; AHA; anterior hypothalamic area; ANOVA; analysis of variance; ANG II; angiotensin II; AT1; ANG II type 1; CAP; angiotensin-converting enzyme inhibitor captopril; CeA; central nucleus of the amygdala; DAMGO; [D-Ala2, N-Me-Phe4,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies

Keywords: ChIP-loop; 3C combined with ChIP; ATR-X; Alpha-Thalassemia mental Retardation, X-linked; ARS; autonomously replicating sequence; CTCF; CCCTC-binding factor; ChIP; chromatin immunoprecipitation; ChIA-PET; Chromatin Interaction Analysis by Paired-End Tag se

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Making surrogate β-cells from mesenchymal stromal cells: Perspectives and future endeavors

Keywords: ADMSCs; adipose tissue derived mesenchymal stromal cells; AFSCs; amniotic fluid-derived stem cells; AMMSCs; amniotic membrane mesenchymal stromal cells; BMMSCs; bone marrow mesenchymal stromal cells; BMP; bone morphogenic protein; CD; cluster of different

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: An overview of Down syndrome, autism, Fragile X and Rett syndrome

Keywords: Intellectual disability; Mitochondria; Mitochondrial dysfunction; Oxidative phosphorylation; Neurogenesis; Neuroplasticity; Down syndrome; Rett syndrome; Autism; Fragile X; Oxidative stress; Drug development; Epigallocatechine-3-gallate; ANT; adenine nucl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Neuregulin 1/ErbB4 enhances synchronized oscillations of prefrontal cortex neurons via inhibitory synapses

Keywords: ACSF; artificial cerebrospinal fluid; CTL; control; EEG; electroencephalogram; EGFP; enhanced green fluorescent protein; EGTA; ethylene glycol tetraacetic acid; FS; fast spiking; HEPES; 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; I; interval;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2014 سفارش ترجمه

A promising approach to iPSC-based cell therapy for diabetic wound treatment: Direct lineage reprogramming

Keywords: IPSCs; induced pluripotent stem cells; ESCs; embryonic stem cells; MSCs; mesenchymal stem cells; DFU; diabetic footulcer; NSCs; neural stem cells; Diabetic wound; Induced pluripotent stem cells; Direct reprogramming; Transdifferentiation; Embryonic stem c

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2014 سفارش ترجمه

Non-toxic conformer of amyloid β may suppress amyloid β-induced toxicity in rat primary neurons: Implications for a novel therapeutic strategy for Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ40; 40-mer amyloid β-protein; Aβ42; 42-mer amyloid β-protein; DIV; days in vitro; IgG; immunoglobulin G; iPSCs; induced pluripotent stem cells; MTT; 3-(4,5-di-methylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NMR; nucle

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

GABAB receptors resist acute desensitization in both postsynaptic and presynaptic compartments of periaqueductal gray neurons

Keywords: aCSF; artificial cerebrospinal fluid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; AP-5; D-2-amino-5-phosphonopentanoic acid; CGP52432; 3-[[[(3,4-dichlorophenyl)methyl]amino]propyl] (diethoxy-methyl) phosphinic acid; CNS; central nervous

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Reprogramming of mouse fibroblasts into induced pluripotent stem cells with Nanog

Keywords: iPSCs; Nanog; Bmi1; Sonic hedgehog;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

ALX 1393 inhibits spontaneous network activity by inducing glycinergic tonic currents in the spinal ventral horn

Keywords: ACSF; artificial cerebrospinal fluid; IPSCs; inhibitory postsynaptic currents; GlyT2; glycine transporter 2; glycine receptor; spinal cord; ventral horn; organotypic culture; ALX 1393; glycine transporter type 2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Peroxynitrite alters GABAergic synaptic transmission in immature rat hippocampal slices

Keywords: Peroxynitrite; GABAergic synaptic transmission; Immature brain; IPSCs; Ca2+ channels; Interneurons;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Significant differences in genotoxicity induced by retrovirus integration in human T cells and induced pluripotent stem cells

Keywords: iPSCs; induced pluripotent stem cells; ESC; embryonic stem cell; LTR; long terminal repeat; SMA; spinal muscular atrophy; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; MEF; mouse embryonic fibroblasts; EB; embryoid bodies; FACS; fluores

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Oligodendrogenesis from neural stem cells: Perspectives for remyelinating strategies

Keywords: MS; multiple sclerosis; NPCs; neural precursor cells; CNS; central nervous system; PDGFRα; platelet-derived growth factor receptor alpha; OPCs; oligodendrocyte precursor cells; PNS; peripheral nervous system; NSCs; neural stem cells; SVZ; subventricular

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells

Keywords: maGSCs; multipotent adult germline stem cells; EGCs; embryonic germ cells; iPSCs; induced pluripotent stem cells; ECCs; embryonic carcinoma cells; GC-1; a spermatogonia cell line; RIP; RNA-binding protein immunoprecipitation; ESCs; Dazl; Splice variant; T

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Repeated restraint stress impairs auditory attention and GABAergic synaptic efficacy in the rat auditory cortex

Keywords: 2-ACT; two-alternative choice task; A1; primary auditory cortex; CE; central amygdaloid nucleus; dB; decibel; DS; difference score; DS-CT; difference score of correct trials; EGTA; ethylene glycol tetraacetic acid; EPSCs; excitatory postsynaptic currents;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Lineage Specifiers: New Players in the Induction of Pluripotency

Keywords: Reprogramming; iPSCs; Pluripotency; Lineage specifier; Seesaw model; Cell fate conversion

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Induced Pluripotency for Translational Research

Keywords: iPSCs; Pluripotency; Cell fate decision; Translational medicine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Induced Pluripotent Stem Cells Are Sensitive to DNA Damage

Keywords: iPSCs; MEF cells; γ-H2AX; DNA damage; Whole-genome sequencing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Vitamin C facilitates pluripotent stem cell maintenance by promoting pluripotency gene transcription

Keywords: Vitamin C; iPSCs; Reprogramming; Pluripotency; Nanog;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Neurosteroids, stress and depression: Potential therapeutic opportunities

Keywords: 5α-DHP; 5α-dihydroprogesterone; 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3α5β-PC; 3α,5β-20-oxo-pregnane-3-carboxylic acid; 17-PA; 3α5α-17-phenylandrost-16-en-3-ol; ANT; adenine nucleotide transporter; ACTH; adrenocorticotrophic hormone; alloP; a

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Clinical Application of Basic ScienceNew horizons for stem cell therapy in liver disease

Keywords: ECM; extra-cellular matrix; EPCs; endothelial progenitor cells; HLCs; hepatocyte-like cells; HPC; hepatic progenitor cell; iPSCs; induced pluripotent stem cells; MMP; matrix metalloproteinase; MSCs; mesenchymal stem cells; Stem cell; Cell therapy; Liver d

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties

Keywords: ACSF; artificial cerebral spinal fluid; AHP; afterhyperpolarization; AP; action potential; AP5; D-2-amino-5-phosphonovalerate; 4-AP; 4-aminopyridine; AVPNs; airway vagal preganglionic neurons; CbTx; charybdotoxin; cNA; compact portion of the nucleus ambig

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه