Keywords: Nanotoxicity; Silver nanoclusters; Reactive oxygen species; Oxidative dissolution; Lysosome degradation; Safety redesign of nanoparticles; ALDH4A1; aldehyde dehydrogenase 4 family member A1; BAD; Bcl-2-associated death promoter; BAX; Bcl-2-associated X pr
مقالات ISI (ترجمه نشده)
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Keywords: α-LA; α-lactalbumin; OA; oleic acid; HAMLET; human alpha-lactalbumin made lethal to tumor cells; LF; lactoferrin; ANS; 1-anilino-8-naphthalenesulfonate; DMEM; Dulbecco's Modified Eagle's Medium; PBS; phosphate buffer solution; PI; propidium iodide; PVDF
Keywords: CAT; catalase; CM; carbamate pesticide; DDVP; dichlorvos; DNPH; 2, 4-dinitrophenylhydrazine; FIDs; free induction decays; FT; Fourier transformation; 3-HB; 3-hydroxybutyrate; LD50; half-lethal doses; LDL/VLDL; low- and very low- density lipoprotein; MAL;
Keywords: GFP; green fluorescent protein; LD50; 50% lethal dose; RDAP; regulated delayed attenuation phenotype; RDAS; regulated delayed antigen synthesis; Salmonella; Carrier; Vaccine; Foreign antigen; Metabolic burden; Over-attenuation;
Keywords: ADD; average daily dose; COPC; contaminant of potential concern; CR; concentration ratio; EA; environmental assessment; EFW; energy-from-waste; EHQ; environmental hazard quotient; EPC; exposure point concentration; ERA; environmental risk assessment; HHRA
Keywords: 2-PAM Cl; pralidoxime chloride; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; BBB; blood brain barrier; ChE; cholinesterase; CNS; central nervous system; CWNA; chemical weapon nerve agent; FDA; Food and Drug Administration; HI-6 DMS; 1-(((4-(am
Keywords: Influenza; Virus; Neuraminidase; Inhibitor; Pharmacokinetics; Molecular modeling; BQLKEXSYWRBWQK-AFMQGRBTSA-N; AUC; area under the concentration-versus-time curve; CC50; 50% cytotoxicity concentration; CL; clearance; CPE; cytopathic effect; D; distributio
Keywords: Space radiation; Solar particle event; Radiation countermeasures; Acute effects of radiation; Long-term effects of radiation; ARS; acute radiation sickness; aPTT; activated partial thromboplastin time; BBI; Bowman-Birk inhibitor; BBIC; BBI concentrate;
Keywords: BSG; buffered saline with gelatin; LD50; lethal dose,50%; LPS; lipopolysaccharides; OMP; outer membrane protein; Fowl typhoid; Poultry; Live attenuated vaccines; Regulated delayed attenuation; Lipopolysaccharides;
Keywords: ACN; acetonitrile; ATAC; trimethyl ammonium compounds; BDMA; benzyl dimethyl ammonium compounds; C12BDMA; dodecyl benzyl dimethyl ammonium chloride; C14BDMA; tetradecyl benzyl dimethyl ammonium chloride; C16BDMA; hexadecyl benzyl dimethyl ammonium chlorid
Keywords: 7-KC; 7 ketocholesterol; ACAT; acyl-CoA cholesterol acyl transferase; CHEH; cholesterol-5-6-epoxide hydrolase; CNS; central nervous system; CT; cholestane 3β-5α-6β triol; EC; epoxycholesterol; EGF; epidermal growth factor; ER; endoplasmic reticulum; ER
Keywords: ADME; absorption, distribution, metabolism and excretion; 3D; three-dimensional; 3T3; “3-day transfer” mouse fibroblast cell line; AGGR; aggregating brain cell cultures; DIV; day in vitro; EU CLP; European regulation on classification, labelling and p
Keywords: ADH; aldehyde dehydrogenase; BMD; benchmark dose; BMDL10; benchmark dose lower bound 10%; bw; body weight; CYP; cytochrome P450; DCA; 1,3-dichloroacetone; 1,3-DCP; 1,3-dichloro-2-propanol; 2,3-DCP; 2,3-dichloro-1-propanol; EC; the European Commission; EFS
Keywords: Biotoxin; Bioterrorism; Biological warfare agent; BW; Biological warfare; CW; chemical weapons; BWAs; Biological warfare agents; BoNTs; Clostridium botulinum neurotoxins; LD50; median lethal dose; PBT; pentavalent botulinum toxoid; SEB; Staphylococus aure
Keywords: AHR; aryl hydrocarbon receptor; AHR-KO; aryl hydrocarbon receptor knockout; Ahrr; aryl hydrocarbon receptor repressor; AIP; aryl hydrocarbon receptor interacting protein; ALB; serum albumin; ALP; alkaline phosphatase; ALT; alanine aminotransferase; ARNT;
Keywords: Inositol; Insulin resistance; Diabetes; Polycystic ovary syndrome; Metabolic syndrome; Diabetic neuropathy; AC; adenylyl cyclase; ACC; acetyl-coenzyme A carboxylase; AGEs; advanced glycation end products; AMP; adenosine monophosphate; cAMP; cyclic AMP; AM
Keywords: Mutation breeding; Gamma rays; Grapes; LD50; Muscat; Red Globe;
Achyranthes aspera Linn. alleviates cerebral ischemia-reperfusion-induced neurocognitive, biochemical, morphological and histological alterations in Wistar rats
Keywords: AP-1; activator protein-1; BCCO; bilateral common carotid occlusion; LD50; lethal dose 50%; DCFH-DA; dichloro-dihydro-fluorescein diacetate; DMEM; dulbecco's modified eagle medium; DPI; diphenylene iodonium; DPPH; 2, 2-diphenyl-1-picrylhydrazyl; DTNB; 5,5
Cloning, characterization, antibacterial activity and expression of hamp in pond loach (Misgurnus anguillicaudatus) after bacterial challenge with Aeromonas hydrophila
Keywords: Hepcidin; hamp1; Antimicrobial peptides; Gene expression; M. anguillicaudatus; A. hydrophila; AMP; Antimicrobial peptide; qRT-PCR; Quantitative Polymerase Chain Reaction; aa; amino acid; pI; Theoretical isoelectric point; EC; Extinction coefficient; II; I
Anti-inflammatory activity and gastroprotective effect of Hertia cheirifolia L. roots extract
Keywords: V; Volume; NaCl; Sodium chloride; HCl; Hydrochloric acid; mm; millimeter; LD50; median lethal dose; Hertia cheirifolia; Anti-inflammatory; Gastroprotective; Liquid chromatography;
A 37â¯kDa Txp40 protein characterized from Photorhabdus luminescens sub sp. akhurstii conferred injectable and oral toxicity to greater wax moth, Galleria mellonella
Keywords: Insecticidal toxins; Protein expression; LD50; LT50; Bioassay; Bacterial strains;
Antimutagenic activity of compounds isolated from Ajuga bracteosa Wall ex. Benth against EMS induced mutagenicity in mice
Keywords: DDMP; 2, 3-dihydro-3, 5-dihydroxy-6-methyl-4H-pyran-4-one; 5HMF; 5- (hydroxymethyl)-2-furan carboxaldehyde; CPCSEA; Committee for the Purpose of Control and Supervision of Experiments on Animals; LD50; Lethal dose at which mortality is 50%; mg/kgbw; milli
Monitoring of hydrogen peroxide production under photodynamic treatment using protein sensor HyPer
Keywords: cpYFP; circular permutated yellow fluorescent protein; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; DMEM; Dulbecco's Modified Eagle's Medium; EPR; endoplasmic reticulum; LD50; half-lethal light dose; LED; light emitting diode; MTT; 3-(4,5-dimethyl-2-t
Anti-scorpion venom activity of Thapsia garganica methanolic extract: Histopathological and biochemical evidences
Keywords: B. occitanus; Buthus occitanus; LD50; Median lethal dose; LD99; Lethal Dose 99; IC 50; Concentration of 50% inhibition; LDH; Lactate deshydrogenase; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; CPK; Créatine phosphokinase; T. garganica
Betulinic, oleanolic and ursolic acids inhibit the enzymatic and biological effects induced by a P-I snake venom metalloproteinase
Keywords: Local tissue damage; Metalloproteinase; Molecular docking; Snake venom; Triterpenic acids; BA; betulinic acid; CK-NAC; creatine kinase activated by N-acetyl cysteine; CM-Sephadex; carboxymethyl sephadex; IC50; half maximal inhibitory concentration; i.p.;
In vitro potency determination of botulinum neurotoxin serotype A based on its receptor-binding and proteolytic characteristics
Keywords: Botulinum neurotoxin serotype A (BoNT/A); In vitro assay; Binding and cleavage assay (BINACLE assay); Activity determination; BINACLE; Binding and cleavage assay; BoNT; Botulinum neurotoxin; BSA; Bovine serum albumin; GT1b; Trisialoganglioside GT1b; H-cha
Effects of a new antiprotozoal drug, N,Nâ²-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria
Keywords: Liver mitochondria; Mitochondrial swelling; Amidine derivatives; Methoxyamidine; Respiratory chain enzymes; ATPase activity; ÎÏm; mitochondrial transmembrane potential; A; absorbance; ADP; adenosine diphosphate; AIDS; acquired immunodeficiency syndrome;
Theoretical research in structure characteristics of different inhibitors and differences of binding modes with CBP bromodomain
Keywords: CBP; CREB (cAMP responsive element binding protein) binding protein; BRD; bromodomain; CPI-098; (4R)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one; CPI-703; (4R)-6-(1-tert-butyl-1H-pyrazol-4-yl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-
Study on the developmental toxicity of β-ionone in the rat
Keywords: Embryotoxicity; Food additives; Fragrance chemicals; Reproductive toxicity; Teratogenicity; ADI; acceptable daily intake; BIO; β-ionone; CYP; cytochrome P450; FDA; US Food and Drug Administration; GD; gestation day; γ-GT; γ-glutamyltransferase; GRAS; G
Ameliorating effects of Nigella sativa oil on aggravation of inflammation, oxidative stress and cytotoxicity induced by smokeless tobacco extract in an allergic asthma model in Wistar rats
Keywords: AHR; airway hyperresponsiveness; b.w.; body weight; BALF; BronchoAlveolar Lavage Fluid; CAT; catalase; DGRSDT; (in Frensh Direction Générale de la Recherche Scientifique et du Développement Technologique) General Directorate for Scientific Research and
Development of a new approach of immunotherapy against scorpion envenoming: Avian IgYs an alternative to equine IgGs
Keywords: Aah; Androctonus australis hector; ED50; median effective dose; FCA; Freund's complete adjuvant; FIA; Freund's incomplete adjuvant; Fab; Fragment antigen binding; IgY; yolk immunoglobulin; IgG; Immunoglobulin G; LD50; median lethal dose; NMRI; Naval Medic
Physiologically distinct subpopulations formed in Escherichia coli cultures in response to heat shock
Keywords: LD50; low density subpopulation; HD50; high density subpopulation; VBNC; Viable-But-Non-Culturable; Population heterogeneity; Heat stress; Protein oxidation; VBNC cells; Persisters;
Regulated delayed attenuation enhances the immunogenicity and protection provided by recombinant Salmonella enterica serovar Typhimurium vaccines expressing serovar Choleraesuis O-polysaccharides
Keywords: Regulated delayed attenuation; Recombinant vaccines; S. Typhimurium; S. Choleraesuis; O-polysaccharide; Protection; OPS; O-polysaccharides; NTS; non-typhoidal Salmonella; S. Typhimurium; Salmonella enterica serovar Typhimurium; LPS; lipopolysaccharides; C
Dioscorea zingiberensis C. H. Wright: An overview on its traditional use, phytochemistry, pharmacology, clinical applications, quality control, and toxicity
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; CK; creatine kinase; CNKI; China Knowledge Resource Integrated; CT; clotting time; CVD; cardiovascular disease; D. zingiberensis; Dioscorea zingiberensis C. H. Wright; ELSD; evaporative light
Preclinical safety evaluation of the ethanolic extract from guavira fruits (Campomanesia pubescens (D.C.) O. BERG) in experimental models of acute and short-term toxicity in rats
Keywords: Safety; Acute toxicity; Repeated doses; LD50; Preclinical studies; Campomanesia pubescens; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CNS; central nervous system; EEFCP; ethanolic extract from C. pubescens; HDL; high density lipoprote
Brain damage and neurological symptoms induced by T-2 toxin in rat brain
Keywords: ANOVA; one-way analysis of variance; ATA; alimentary toxic aleukia; atg14; autophagy related 14; atg5; autophagy related 5; bax; Bcl 2 associated X; BBB; Blood brain barrier; BPB; Blood placenta barrier; BSA; bovine serum albumin; Caspase-3; Cysteinyl asp
Nanoencapsulated Thymus capitatus essential oil as natural preservative
Keywords: EO; essential oil; DPPH; 1,1-diphenyl-2-picrylhydrazyl; GC-MS; Gas Chromatography-Mass Spectrometry; IC50; concentration inhibiting 50% of the observed effect; IZ; inhibition zone diameter; LD50; median lethal dose; L.R.I.; Linear Retention Index; MIC
Isolation, identification and characterization of Klebsiella pneumoniae from infected farmed Indian Major Carp Labeo rohita (Hamilton 1822) in West Bengal, India
Keywords: Klebsiella pneumoniae; 16S rRNA gene; Histopathology; LD50; Biochemical test;
Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications
Keywords: 2,2â²-bipy; 2,2-bipyridine; 6-mepic; 6-methylpicolinic acid; acac; acetylacetone; Ad; adenosine; Ala; alanine; Ala-Gly; alanylglycine; Ala-His; alanylhistidine; Ala-Ser; alanylserine; Asp; aspartic acid; BEOV; bis(ethylmaltolate)oxovanadium(IV); Cys; cys
Evaluation of in vivo wound healing and anti-inflammatory activity of crude extract of the fruits of Brucea antidysentrica in mice
Keywords: AAU; Addis Ababa University; ANOVA; analysis of variance; COX; cyclooxygenase; EP; epithelialization Period; EPHI; Ethiopian Public Health Institute; LD50; medial lethal dose; MF; master formula; MFE; methanol fruit extract; OECD; Organization for Economi
Anti-Deinagkistrodon acutus venom properties of ethanolic root extract from Cynanchum paniculatum (Bunge) kitag and its GC-MS analysis
Keywords: CK; creatine kinase; CPER; ethanolic root extract of C. paniculatum; DAV; Deinagkistrodon acutus venom; ED50; effective dose 50; GC-MS; gas chromatography-mass spectrometry; i.m.; intra-muscularly; i.p.; intraperitoneally; i. pl.; intraplantarly; LD50;
Coordination chemistry of 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane (PTA) and derivatives. Part III. Variations on a theme: Novel architectures, materials and applications
Keywords: PTA; 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane; HPTA; 1-H-1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane; mPTA; 1-methyl-1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane; PTABn; 1-benzyl-1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane; PTAS; 1,3,5-triaza-7-
Superior efficacy of HI-6 dimethanesulfonate over pralidoxime methylsulfate against Russian VX poisoning in cynomolgus monkeys (Macaca fascicularis)
Keywords: AIBC; dual-chambered autoinjector; AS; atropine sulfate; AVZ; avizafone chlorhydrate; HI-6 DMS; HI-6 dimethanesulfonate; OPNA; organophosphorus nerve agents; i.m.; intramuscular; i.v.; intravenous; LD50; lethal dose 50%; ChEs; cholinesterases; AChEs; acet
Bioconversion of alkaloids to high-value chemicals: Comparative analysis of newly isolated lupanine degrading strains
Keywords: Lupanine; Quinolizidine alkaloids; Biodegradation; Bioconversion; Toxicity assessment; M9; Minimal microbial growth medium; GC; Gas chromatography; EC50; Half maximal effective concentration; ITS; Internal transcribed spacer sequence; NCBI; National Cente
Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy
Keywords: A2058; human metastatic melanoma cell; A2780; human ovarian carcinoma cell; A2780cisR; cisplatin-resistant A2780; A375; human melanoma cell; A549; human lung adenocarcinoma epithelial cell; A549R; cisplatin-resistant A549 cell; Aβ; beta-amyloid; acac; ac
Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats
Keywords: MeCO; methanolic root extract of Colebrookea oppositifolia; I/R; ischemia reperfusion; DPPH; 2, 2-diphenyl-L-picrylhydrazyl; FRAP; ferric reducing antioxidant power; ORAC; oxygen radical absorbance capacity; LPS; lipopolysaccharide; LC-MS/MS; liquid chrom
Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses
Keywords: Acylguanidine; Zanamivir; Oseltamivir; Neuraminidase inhibitor; Influenza; Arg; arginine; Boc; tert-butoxycarbonyl; (Boc)2O; di(tert-butyl) dicarbonate; CC50; half maximal cytotoxicity concentration; CPE; cytopathic effect; DIEA; diisopropyl ethylamine; D
A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine
Keywords: Aconitum carmichaeli Debx.; Aconitum alkaloids; Pharmacokinetics; Herb-drug interactions; Toxicology; Personalized medicine; DMEs; drug-metabolizing enzymes; ETs; efflux transporters; BB; bioavailability barrier; DDAs; diester-diterpene alkaloids; MDAs; m
Tithonia diversifolia (Hemsl.) A. Gray as a medicinal plant: A comprehensive review of its ethnopharmacology, phytochemistry, pharmacotoxicology and clinical relevance
Keywords: ABTS; 2,2â²-Azinobis (3-ethylbenzothiazoline-6-sulphonate); Ach; acetyl choline; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AMPK; 5' adenosine monophosphate-activated protein kinase; AST; Aspartate transaminase; CAs; chlorogenic acids; CC5
Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Alpinia oxyphylla Miquel: A review
Keywords: AD; Alzheimer's disease; AcOEt; Ethyl acetate; AOE; Ethanolic extract of the fruit of A. oxyphylla; AOF; Alpinia oxyphylla fruit; BBB; Blood-brain barrier; CAT; Catalase; CCl4; Carbon tetrachloride; CKD; Chronic kidney disease; EA portion; Ethyl acetate-s