Keywords: CCL11; C-C motif chemokine; EGF; epidermal growth factor; FoxP3; forkhead box P3; G-CSF; granulocyte colony-stimulating factor; GM-CSF; granulocyte-macrophage colony-stimulating factor; HELLP; hemolysis elevated liver enzymes and low platelets; MIP; macro
مقالات ISI (ترجمه نشده)
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Keywords: Small molecules; biologics; adverse effects mouth; BP; Bisphosphonates; EGFR; Epidermal growth factor receptor; FDA; Food and Drug Administration; HER2; Human epidermal growth factor receptor 2; HNSCC; Head and neck squamous cell carcinoma; mAbs; Monoclon
Keywords: Lectins; Molecular farming; Monoclonal antibodies; Plant secondary metabolites; Therapeutic anti-cancer vaccines; APIs; active pharmaceutical ingredients; ADCC; antibody-dependent cellular cytotoxicity; ADCs; antibody-drug conjugates; ATPS; aqueous two-
Keywords: Automation; ÃKTA Pure; Protein purification; Parallel loading; mAbs;
Keywords: Glycosylation; Glycoform; Nucleotide sugars; Biosimilar; Immune effector functions; mAbs; Therapeutic protein; Glutamine; Ammonia; Animal cell culture;
Keywords: 2â²-F-Py; 2â²-fluoro-pyrimidines; 3D; three-dimensional; 3WJ; three-way junction; AMD; age-related macular degeneration; AuNPs; gold nanoparticles; BBB; blood-brain barrier; Bcl-2; B-cell lymphoma 2; BM; bone marrow; CCL2; chemokine C-C motif ligand 2;
Keywords: CRP; Critical Reagents Program; GST; Glutathione S-transferase; GP; Glycoprotein; mAbs; Monoclonal antibodies; NP; Nucleoprotein; sdAb; Single domain antibodies; SPR; Surface plasmon resonance; VP40; Viral protein 40; Ebola virus; Surface plasmon resonanc
Keywords: APCs; antigen presenting cells; APM; Antigen Processing Machinery; β2-m; β2-microglobulin (β2-m, only in Table and Figures); DCs; dendritic cells; HLA; human leukocyte antigen; LCs; Langerhans cells; MHC; major histocompatibility complex; mAbs; monoclo
Keywords: APC; antigen presenting cells; CRD; carbohydrate recognition domain; DCs; dendritic cells; GDF-15; growth differentiation factor-15; IL; interleukin; IDO; indoleamine 2,3-dioxygenase; IFN-γ; interferon-γ; LXR; liver X receptors; M-CSF; macrophage-colony
Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies
Keywords: Therapeutic monoclonal antibodies; Isoelectric points; Charge variants; Imaged capillary isoelectric focusing; Cation exchange chromatography; Developability; mAbs;
Keywords: Biologics; asthma; urticaria; nasal polyps; mAbs; cytokines; IgE; CAPS; Cryopyrin-associated periodic syndrome; DPP-4; Dipeptidyl peptidase 4; FDA; US Food and Drug Administration; Feno; Fraction of exhaled nitric oxide; IVIG; Intravenous immunoglobulin;
Keywords: Biologics; small molecule inhibitors; topical therapy; cytokines; mAbs; precision medicine; AD; Atopic dermatitis; AhR; Aryl hydrocarbon receptor; CRTH2; Chemoattractant receptor homologous molecules expressed on TH2 lymphocytes; EASI; Eczema Area and Sev
Keywords: Anaphylaxis; adverse drug reactions; drug hypersensitivity reactions; hypersensitivity reactions; IgE; mAbs; ACE; Angiotensin-converting enzyme; ED; Emergency department; FTEIA; Food-triggered exercised-induced anaphylaxis; THIQ; Tetrahydroisoquinoline;
Keywords: CGRP; calcitonin gene related peptide; CSD; cortical spreading depression; NSAIDs; non-steroidal anti-inflammatory drugs; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; NO; nitric oxide (NO); TG; trigeminal ganglion; TNC; trigeminal nucleu
Keywords: Ab; antibody; BM; bone marrow; CA; carbonic anhydrase; CCL; C-C motif chemokine ligand; CTL; cytotoxic T lymphocyte; DC; dendritic cell; FAO; fatty acid oxidation; GPCR; G-protein-coupled receptors; ICI; immune checkpoint inhibitor; IL; interleukin; mAbs;
Keywords: subcutaneous injection; injection volume; injection pain; combination products; hypodermis; health care; ECM; extracellular matrix; mABs; monoclonal Antibodies; SC; subcutaneous;
Keywords: ADCC; antibody dependent cellular cytotoxicity; AUC; area under the concentration-time curve; CL; clearance; mAbs; monoclonal antibodies; M-M; Michaelis-Menten; PBS; phosphate-buffered saline; PK; pharmacokinetic; TMB; tetramethylbenzidine; TMDD; ta
Keywords: AHR; airway hyperresponsiveness; ACQ; Asthma Control Questionnaire; ACOS; asthma-COPD overlap syndrome; BAL; bronchoalveolar lavage; CLCA1; chloride channel regulator 1; COPD; chronic obstructive lung disease; CS; corticosteroids; CXCR; CXC chemokine rece
Keywords: CV; coefficients of variation; mABS; milli absorbance; MS; mass spectrometry; Crustacean; Food allergy; Enzyme immunoassay; Lateral flow assay;
Keywords: sFLC; serum free light chain; κ; kappa; λ; lambda; sFLC κ/λ ratio; ratio of κ sFLC to λ sFLC concentration; MM; multiple myeloma; LCMM; light chain MM; IIMM; intact immunoglobulin MM; NSMM; nonsecretory MM; LCDD; light chain deposition disease; MGUS
Keywords: Aves; L chains; Sequences; Cross-reactivity; mAbs;
Keywords: 2 DE; 2-dimensional electrophoresis; ABPP; activity-based protein profiling; BFGF; basic fibroblast growth factor; CML; chronic myeloid leukemia; CRC; colorectal cancer; DIGE; differential in gel electrophoresis; EGF(R); epidermal growth factor (receptor)
Keywords: A450nm; absorbance at 450Â nm; ACD; allergic contact dermatitis; ACM; allergic contact mucositis; Ags; antigens; ANOVA; analysis of variance; APC; allophycocyanin; DTH; delayed-type hypersensitivity; EDTA; ethylenediaminetetraacetic acid; ELISA; enzyme-li
Keywords: α-A-NP; anti-influenza A nucleoprotein; BSA; bovine serum albumin; C+; normalized concentration; CCD; charge-coupled device; D+; normalized location across the micromixer; DI; deionized; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme-linked immu
Keywords: AbX; antibody with mostly fucosylated glycans; AbX-AF; antibody with completely afucosylated glycans; ADCC; antibody-dependent cell-mediated cytotoxicity; AICC; antibody-independent cell-mediated cytotoxicity; CV; coefficient of variation; EC50; half maxi
Keywords: Radionuclide production; Iodine-124; Positron emission tomography (PET); Iodine radiolabeling; CT; computed tomography; mAbs; monoclonal antibodies; MRI; magnetic resonance imaging; PET; positron emission tomography; SPECT; single-photon emission computed
Keywords: BUP; Buprenorphine; MAbs; Monoclonal antibodies; GC; Gas chromatography; LC; Liquid chromatography; MS; Mass spectrometry; BSA; Bovine serum albumin; BTG; Bovine thyroglobulin; ELISA; Enzyme-linked immunosorbent assay; PBS; Phosphate-buffered saline; TMB;
Keywords: UHPLC; High resolution separations; Monoclonal antibodies; mAbs; Peak capacity; High temperature;
Keywords: ATCC; American Type Culture Collection; mAbs; monoclonal antibodies; OVA; ovalbumin; BSA; bovine serum albumine; FITC; fluoresceinisothiocyanate; OVA-FITC; fluoresceinisothiocyanate linked to ovalbumin; BSA-FITC; fluoresceinisothiocyanate linked to bovine
Keywords: PBMCs; peripheral blood mononuclear cells; NK; natural killer cells; IL; interleukin; ADCC; antibody-dependent cell-mediated cytotoxicity; FITC; fluorescein isothiacyanate; APC; allophycocyanin; PE; phycoerythrin; PC5; Phycoerythrincyanin 5; mAbs; monoclo
Keywords: cGMP; cyclic guanosine monophosphate; FACS; fluorescence activated cell sorting; GC; guanylyl cyclases; IL; interleukin; mAbs; monoclonal antibodies; NK cells; nature killer cells; NO; nitric oxide; PDE5; phosphodiesterase 5; TCR; T cell receptor; cGMP; G
Keywords: aa; amino acid(s); APMV-1; avian paramyxovirus-1; BH3; Bcl-2 homology domain 3; BGI; Beijing Genomics Institute; BSL-2; biosafety level 2; cDNA; DNA complementary to RNA; F; fusion protein; F; phenylalanine; G; guanine; GE; gene end; GS; gene start; HA; h
Keywords: ARDS; acute respiratory distress syndrome; Asn; asparagine; BSA; bovine serum albumin; CD; cyclodextrin; COPD; chronic obstructive pulmonary disease; dae; diameter of the particles; DPI; dry powder inhaler; DPPC; dipalmitoylphosphatidylcholine; DSPC; dist
Establishment of the cross-clade antigen detection system for H5 subtype influenza viruses using peptide monoclonal antibodies specific for influenza virus H5 hemagglutinin
Keywords: Influenza; Diagnostics; H5 subtype; Monoclonal antibody; Antigen-capture ELISA; HPAI; highly pathogenic avian influenza; mAbs; monoclonal antibodies; HA; hemagglutinin; ELISA; enzyme-linked immunosorbent assay;
Development and evaluation of recombinant antigen and monoclonal antibody based competition ELISA for the sero- surveillance of surra in animals
Keywords: Competitive ELISA; Monoclonal antibody; MAbs; Recombinant VSG; Trypanosoma evansi; Trypanosomosis;
Development and validation of a targeted affinity-enrichment and LC-MS/MS proteomics approach for the therapeutic monitoring of adalimumab
Keywords: Bioavailable adalimumab; Anti-drug antibodies; Quantitative and targeted proteomics; TNFα; anti-tumor necrosis factor alpha; ADAbs; anti-drug antibodies; mAbs; monoclonal antibodies; RA; rheumatoid arthritis; IBD; inflammatory bowel disease; ISTD; intern
Anti-tumour necrosis factor-α antibodies and B cell homeostasis in human inflammatory bowel diseases
Keywords: APC; antigen-presenting cell; BM; bone marrow; GC; germinal centre; IBD; inflammatory bowel disease; UC; ulcerative colitis; CD; Crohn's disease; IFNγ; interferon-gamma; Th; T-helper; IPC; immunoglobulin-producing cell; mAbs; monoclonal antibodies; MBs;
Human monoclonal antibodies neutralizing influenza virus A/H1N1pdm09 and seasonal A/H1N1 strains - Distinct Ig gene repertoires with a similar action mechanism
Keywords: IFV; influenza virus; HA; hemagglutinin; MAbs; monoclonal antibodies; hMAb; human monoclonal antibodies; Nabs; neutralizing antibodies; hnMAbs; human neutralizing monoclonal antibodies; HIV; human immunodeficiency virus; HI; hemagglutination inhibition; s
DNA sequence-specific ligands. XVII. Synthesis, spectral properties, virological and biochemical studies of fluorescent dimeric bisbenzimidazoles DBA(n)
Keywords: topo-I; DNA topoisomerase I; DMT; DNA methyltransferase; HSV-1; herpes simplex virus type 1; CMV; cytomegalovirus; scDNA; supercoiled DNA; b.p.; base pairs; MABs; monoclonal antibodies; ACV; acyclovir; PBS; phosphate buffered saline; PFU/cells; plaque for
Precise immune tolerance for hPSC derivatives in clinical application
Keywords: AAV; adeno-associated virus; ATIIC; lung alveolar epithelial type II cell; B2M; b-2-microglobulin; BAC; bacterial artificial chromosome; CIITA; class-II MHC trans-activator; CP hESC; hESC lines constitutively expressing CTLA4Ig and programmed death-ligand
Toll-like receptors 4, 5, 6 and 7 are constitutively expressed in non-human primate retinal neurons
Keywords: Retina; Non-human primates; Innate immunity; Toll-like receptors; Inflammation; TLR; Toll-like receptor; NHP; Non-human primate; IF; immunofluorescence; qPCR; quantitative polymerase chain reaction; PAMPs; pathogen-associated molecular patterns; NF-κB; n
Study of the allergenic potential of Bacillus thuringiensis Cry1Ac toxin following intra-gastric administration in a murine model of food-allergy
Keywords: Bt; Bacillus thuringiensis; BSA; bovine serum albumin; CT; cholera toxin; Cry1Ac; Cry1Ac toxin; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; FCS; fetal calf serum; GM; genetically modified; H&E; hematoxylin and eosin; LI; large intes
Distinct wall polymer deconstruction for high biomass digestibility under chemical pretreatment in Miscanthus and rice
Keywords: mAbs; monoclonal antibodies; M. sin; Miscanthus sinensis; M. sac; Miscanthus sacchariflorus; XG; xyloglucan; HG; homogalacturonan; RG-I; rhamnogalacturonan-I; Wall polymers; Chemical pretreatment; Lignocellulose hydrolysis; Biomass saccharification; Glyca
Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression
Keywords: PPARγ; Peroxisome proliferator-activated receptor γ; ECM; extracellular matrix; TGF-β; transforming growth factor-β; PI3K; phosphoinositide 3-kinase; F-actin; filamentous-actin; TNF-α; tumor necrosis factor-α; IL; interleukin; FCS; fetal calf serum;
CAR-T cells and combination therapies: What's next in the immunotherapy revolution?
Keywords: CAR; chimeric antigen receptor; iRs; inhibitory receptors; mAbs; monoclonal antibodies; SMIs; Small molecule inhibitors; KIs; kinase inhibitors; CAR-T cells; Solid tumors; Targeted-therapies; Combination therapies; Synthetic biology; Systems biology;
Blockade of vascular endothelial growth factor receptor-1 (Flt-1), reveals a novel analgesic for osteoarthritis-induced joint pain
Keywords: OA; osteoarthritis; PMM; partial medial meniscectomy; h; hour; PWT; paw withdrawal threshold; PTT; paw thermal threshold; DRG; dorsal root ganglion; IT; intrathecal; IA; intraarticular; RT-PCR; Real-time polymerase chain reaction; P; probability; SEM; sta
Aptamers as potential therapeutic agents for ovarian cancer
Keywords: Aptamers; Antibodies; EpCAM; Therapeutic; Targeted therapies; Ovarian cancer; ADCC; antibody-dependent cell-mediated cytotoxicity; ABC; ATP-binding cassette; BBB; blood brain barrier; CDC; complement-mediated cytolysis; CA125; Cancer Antigen 125; CSCs; ca
Induction of plasmablasts by follicular helper T cell-CXCL13 axis upon occurrence of herpes zoster
Keywords: Herpes zoster; Plasmablast; Follicular helper T cell; CXCL13; Varicella zoster virus; APC; Allophycocyanin; CBA; Cytometric bead array; cTfh; Circulating T follicular helper; DENV; Dengue virus; ELISA; Enzyme-linked immunosorbent assay; FITC; Fluorescein
ACE phenotyping in Gaucher disease
Keywords: ACE; angiotensin-converting enzyme; mAbs; monoclonal antibodies; ZPH; Z-Phe-His-Leu - carbobenzoxy-l-phenylalanyl-l-histidyl-L-leucine; HHL; Hip-His-Leu - hippuryl-l-histidyl-l-leucine; CHO cells; Chinese Hamster Ovary cells; PBS; phosphate buffered s
Minimal physiologically-based pharmacokinetic model to investigate the effect of pH dependent FcRn affinity and the endothelial endocytosis on the pharmacokinetics of anti-VEGF humanized IgG1 antibody in cynomolgus monkey
Keywords: AIC; Akaike Information Criterion; ATA; anti-therapeutic antibody; AUC; area under the curve; CLe; antibody clearance in endothelial space; CDP; Complex Dedrick Plot; CV; coefficient of variations; FR; recycling fraction of IgG; F1; modulation factor of m