دانلود مقالات ISI درباره Mecp2 + ترجمه فارسی

Recent insights into genotype-phenotype relationships in patients with Rett syndrome using a fine grain scale

Keywords: Rett syndrome; MECP2; Cognitive processes; Emotion; Motor behaviour; Autonomy;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Respiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 T158A and R168X

Keywords: EPSCs; excitatory post-synaptic currents; MBD; methyl-CpG-binding domain; MeCP2; methyl-CpG-binding protein 2; NLS; nuclear localization signals; NMDA; N-methyl-d-aspartic acid; NTS; nucleus tractus solitarius; PHFD; post-hypoxic decline in respiratory fr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome

Keywords: 4-HNE; 4-hydroxy-2-nonenal; 4-HNE PAs; 4-hydroxy-2-nonenal protein adducts; AdA; adrenic acid; ARA; arachidonic acid; ASDs; autism spectrum disorders; AUs; arbitrary units; BDNF; brain-derived neurotrophic factor; CRE; Cre-Recombinase; DHA; docosahexaenoi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

MeCP2: the long trip from a chromatin protein to neurological disorders

Keywords: MeCP2; intrinsically disordered proteins; chromatin; DNA methylation; neurological disorders

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

MeCP2 is required for activity-dependent refinement of olfactory circuits

Keywords: Olfactory circuitry; MeCP2; Neurodevelopment; Autism spectrum disorder; Rett syndrome;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action

Keywords: Rett syndrome; MeCP2; Structure and function; Molecular genetics; Perturbation in gene expression; Pathway enrichment analysis;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: An overview of Down syndrome, autism, Fragile X and Rett syndrome

Keywords: Intellectual disability; Mitochondria; Mitochondrial dysfunction; Oxidative phosphorylation; Neurogenesis; Neuroplasticity; Down syndrome; Rett syndrome; Autism; Fragile X; Oxidative stress; Drug development; Epigallocatechine-3-gallate; ANT; adenine nucl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

DNA methylation: New therapeutic implications for hepatic fibrosis

Keywords: HSCs; hepatic stellate cells; ECMs; extracellular matrices; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; PDGF; platelet-derived growth factor; DNMTs; DNA methyltransferases; DNMT1; DNA methyltransferase 1; 5-Aza-dC; 5-Aza-2′-de

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Validation of high-resolution DNA melting analysis for mutation scanning of the CDKL5 gene: Identification of novel mutations

Keywords: CDKL5; cyclin-dependent kinase-like 5; HRMA; high resolution melting analysis; DNA; deoxyribonucleic acid; dHPLC; denaturing high performance liquid chromatography; RTT; Rett syndrome; ISSX; infantile spasm syndrome X-linked; MECP2; methyl CpG-binding pro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The role of methyl-CpG binding protein 2 in liver fibrosis

Keywords: HSC; hepatic stellate cell; ECMs; extracellular matrices; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; TRD; Transcriptional Repression Domain; CTD; C-Terminal Domain; PPARγ; peroxisome proliferator-activated receptor-gamma; PDGF

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The epigenetic feedback loop between DNA methylation and microRNAs in fibrotic disease with an emphasis on DNA methyltransferases

Keywords: miRNA; microRNA; DNMTs; DNA methyltransferases; HSC; hepatic stellate cell; IPF; idiopathic pulmonary fibrosis; RASAL; Ras GTPase activating-like protein; SOCS1; cytokine signaling-1 gene; PPARγ; peroxisome proliferator-activated receptor γ; MeCP2; meth

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Down-regulation of MeCP2 in Hirschsprung's disease

Keywords: Hirschsprung's disease; MeCP2; Proliferation; BSP; miRNA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

MeCP2 deficiency enhances glutamate release through NF-κB signaling in myeloid derived cells

Keywords: NF-κB; MeCP2; Glutamate; Microglia; Peripheral blood mononuclear cells;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

New advances of DNA methylation in liver fibrosis, with special emphasis on the crosstalk between microRNAs and DNA methylation machinery

Keywords: miRNAs; small non-coding RNAs; HSC; hepatic stellate cell; ECM; extracellular matrix; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; PDGF; platelet-derived growth factor; FGF; fibroblast growth factor; ICAM-1; intercellular adhesio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Research ReportAltered somatosensory barrel cortex refinement in the developing brain of Mecp2-null mice

Keywords: ANOVA; analysis of variance; CO; cytochrome oxidase; HPLC/EC; high performance liquid chromatography with electrochemical detection; 5-HIAA; 5-hydroxyindoleacetic acid; MeCP2; methyl-CpG binding protein 2; MAO; monoamine oxidase; PBS; phosphate-buffered s

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Breathing challenges in Rett Syndrome: Lessons learned from humans and animal models

Keywords: Pre-Boetzinger Complex; Mecp2; dysautonomia;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic upregulation of Bak by ZBP-89 inhibits the growth of hepatocellular carcinoma

Keywords: 5-Aza-dC; 5-aza-2′-deoxycytidine; ChIP; chromatin immunoprecipitation; Co-IP; co-immunoprecipitation; DNMT; DNA methyltransferase; HCC; hepatocellular carcinoma; HDAC; histone deacetylase; MeCP2; methyl-CpG-binding protein 2; MIHA; immortalized non-tumo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Wnt signaling in liver fibrosis: Progress, challenges and potential directions

Keywords: Liver fibrosis; Wnt signaling; Canonical Wnt signaling pathway; Hepatic stellate cell; Myofibroblastic transdifferentiation; HSCs; hepatic stellate cells; GFAP; glial fibrillary acidic protein; a-SMA; a-smooth muscle actin; TRAIL; tumor necrosis factor-re

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Cocaine represses protein phosphatase-1Cβ through DNA methylation and Methyl-CpG Binding Protein-2 recruitment in adult rat brain

Keywords: Cocaine; Drugs of abuse; DNA methylation; Epigenetics; Protein phosphatase-1; MeCP2; Rett syndrome; CGI; CpG Island; ChIP; chromatin immunoprecipitation; CPP; conditioned place preference; CPu; caudate putamen; CREB; cAMP response element-binding protein;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Research ReportCorrecting deregulated Fxyd1 expression ameliorates a behavioral impairment in a mouse model of Rett syndrome

Keywords: Fxyd1; Mecp2; Learning and memory; Rett syndrome; Novel object recognition; Novel object location; Mouse model;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Morphine withdrawal produces ERK-dependent and ERK-independent epigenetic marks in neurons of the nucleus accumbens and lateral septum

Keywords: Opioids; Epigenetics; ERK; MeCP2; Signal transduction; Molecular & cellular neurobiology; Neuroanatomy; ARC; activity-regulated cytoskeleton-associated protein; ERK; extracellular signal-regulated kinase; DS; dorsal striatum; IEG; immediate early genes; L

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells

Keywords: MOR; mu opioid receptor; JNK; c-Jun NH2-terminal kinase; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated protein/extracellular signal-regulated kinase; NF-κB; nuclear factor-kappaB; DP; distal promoter; PP; proximal promoter; Oct-1; octame

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of the MIR155 host gene in physiological and pathological processes

Keywords: 3T3-L1; cell line derived from 3T3 cells; 3′-UTR; 3′-untranslated region; AICDA; activation-induced cytidine deaminase; AML; acute myeloid leukemia; Ang II; angiotensin II; AP-1; activator protein 1; AT1R; angiotensin II type 1 receptor; BACH1; basic

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2013 سفارش ترجمه

miR-132 enhances HIV-1 replication

Keywords: microRNA; miR-132; HIV; MeCP2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Ube3a/E6AP is involved in a subset of MeCP2 functions

Keywords: Rett syndrome; Angelman syndrome; Ube3a/E6AP; MeCP2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse

Keywords: MECP2; IRAK1; Lupus; Epigenetics; Polymorphism; DNA methylation; T cells; Transgenic mouse

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Permanent and plastic epigenesis in neuroendocrine systems

Keywords: Epigenetic; MeCP2; Sexual differentiation; Methylation; Vasopressin; Brain; Histones; Coactivators; Sex difference; Steroid hormones

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

MeCP2 deficiency is associated with impaired microtubule stability

Keywords: Rett syndrome; MeCP2; Microtubule; Fibroblast

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Rett syndrome treatment in mouse models: Searching for effective targets and strategies

Keywords: Intellectual disability; Neurodevelopmental disorders; MeCP2; Therapeutic approach

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Novel non-identical MECP2 mutations in Rett syndrome family: A rare presentation

Keywords: De-novo; MECP2; Mosaicism; Mutation; Non-identical; Rett syndrome; SSCP; X-chromosome inactivation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

MECP2 triplication in 3 brothers – A rarely described cause of familial neurological regression in boys

Keywords: MECP2; Xq28; Neurological regression; Triplication

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Congenital variant of Rett syndrome due to an intragenic large deletion in MECP2

Keywords: Rett syndrome; Congenital variant; MECP2; Deletion; MLPA

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Spontaneous recurrent mutations and a complex rearrangement in the MECP2 gene in the light of current models of mutagenesis

Keywords: Rett syndrome; MECP2; Mutations; Indel; Mutagenesis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

MeCP2+/− mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder

Keywords: Sensory evoked potential; SEP; Auditory evoked potential; AEP; ERP; MeCP2; Preclinical model; Mouse; Gamma oscillation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular characteristics of Chinese patients with Rett syndrome

Keywords: Rett syndrome; Molecular characteristics; MECP2; CDKL5; FOXG1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular diagnostic dilemmas in Rett syndrome

Keywords: MECP2; Rett syndrome; Autism; Mental retardation; Mutational analysis; XLMR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Reduced expression of the mu opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G

Keywords: A118G; knock-in mouse; mu opioid receptor; N-glycosylation; autoradiography; A/A; homozygous for A112 allele; CPu; caudate putamen; G/G; homozygous for G112 allele; MeCP2; methyl-CpG-binding protein 2; MOPR; mu opioid receptor; NAc; nucleus accumbens; OPR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Epileptic seizures, movement disorders, and breathing disturbances in Rett syndrome: Diagnostic relevance of video-polygraphy

Keywords: Rett syndrome; Video-polygraphy; Myoclonus; Epilepsy; MECP2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Oxytocin receptor and Mecp2308/Y knockout mice exhibit altered expression of autism-related social behaviors

Keywords: Autism; Oxytocin receptor; Mecp2; Social behavior; Mouse models

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Normal mitral cell dendritic development in the setting of Mecp2 mutation

Keywords: olfaction; Rett syndrome; mitral cell; dendrite development; Mecp2; autism spectrum disorder; EPL; external plexiform layer; LOT; lateral olfactory tract; MC; mitral cells; MECP2; methyl CpG binding protein 2; OB; olfactory bulb; OMP; olfactory marker pro

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular analysis of MECP2 gene in Egyptian patients with Rett syndrome

Keywords: Rett syndrome (RTT); MECP2; Missense; Nonsense; XCI

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

MECP2 mutations and clinical correlations in Greek children with Rett syndrome and associated neurodevelopmental disorders

Keywords: MECP2; Rett syndrome; Mental retardation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis

Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Neurodegeneration the RNA way

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; Aβ42; amyloid β - 42 amino acids; CUGBP1; CUG binding protein 1; DM1; myotonic dystrophy type 1; DM2; myotonic dystrophy type 2; FTD; frontotemporal dementia;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Increased levels of 4HNE-protein plasma adducts in Rett syndrome

Keywords: CDKL5, cyclin-dependent kinase-like 5; FOXG1, forkhead box protein G1; 4HNE-PAs, 4-hydroxynonenal protein adducts; MeCP2, methyl-CpG-binding protein 2; RTT, Rett syndromeRett syndrome; MeCP2; CDKL5; FOXG1; Oxidative stress; 4-Hydroxynonenal

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression

Keywords: Rett Syndrome; Reversal of X-inactivation; Allele-specific cell-line; MeCP2; Nested PCR;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Somatic mosaicism for Y120X mutation in the MECP2 gene causes atypical Rett syndrome in a male

Keywords: Rett Syndrome; MECP2; Somatic mosaicism; Male patient

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Late-onset mental deterioration and fluctuating dystonia in a female patient with a truncating MECP2 mutation

Keywords: Rett syndrome; MECP2; Truncating mutation; Preserved speech variant; Asymmetrical dystonia; Phenotype; Genotype;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Epigenetic organization of brain sex differences and juvenile social play behavior

Keywords: Epigentic; Methylation; Methyl-binding proteins; Sex differences; Juvenile social play; Corepressor; MeCP2; NCoR; Estrogen receptors; Amygdala; Preoptic area

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The Dinucleotide CG as a Genomic Signalling Module

Keywords: CpG islands; DNA methylation; MeCP2; Cfp1CGIs, CpG islands; H3K4me3, trimethylation of lysine 4 of histone H3; MBD, methyl-CpG binding domain

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه