
Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression
Keywords: ARBs; Angiotensin II type 1 receptor blockers; TAC; transverse aortic constriction; AF; atrial fibrillation; EMT; Epithelial-to-mesenchymal transition; MMPs; matrix metalloproteinases; LVAWD and LVPWD; left ventricular anterior and posterior wall at end-d