Scaling up synthetic biology: Do not forget the chassis
Keywords: چاپرون مولکولی; Genetic program; NanoRNase; Molecular chaperone; Ageing; Logicome; Paleome; Cenome;
مقالات ISI چاپرون مولکولی (ترجمه نشده)
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Sodium arsenite and cadmium chloride induction of proteasomal inhibition and HSP accumulation in Xenopus laevis A6 kidney epithelial cells
Keywords: چاپرون مولکولی; Proteasomal inhibition; Molecular chaperone; Amphibian; Frog; Ubiquitin; Heat shock proteins;
Chaperoning α7 neuronal nicotinic acetylcholine receptors
Keywords: چاپرون مولکولی; Molecular chaperone; RIC-3; α7; Receptor trafficking;
Molecular and functional characterization of HdHSP20: A biomarker of environmental stresses in disk abalone Haliotis discus discus
Keywords: چاپرون مولکولی; Abalone; HSP20; Molecular chaperone; Environmental stress; Biomarker
A screen for modulators of large T antigen’s ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication
Keywords: چاپرون مولکولی; Polyomavirus; Bithionol; Hexachlorophene; T antigen; Molecular chaperone; High throughput screen
The network interaction of the human cytosolic 90 kDa heat shock protein Hsp90: A target for cancer therapeutics
Keywords: چاپرون مولکولی; Hsp, heat shock protein; PQC, protein quality controlHsp90; Protein folding; Molecular chaperone; Heat shock protein; Cancer
Characterization of rpoH in Acetobacter pasteurianus NBRC3283
Keywords: چاپرون مولکولی; Acetobacter pasteurianus; Acetic acid bacteria; Acetic acid fermentation; rpoH; Molecular chaperone
Single molecule FRET detection in CdSe-QD donor and Cy5-labeled molecular chaperone acceptor complex by imaging microscopy
Keywords: چاپرون مولکولی; Single molecule detection; FRET; CdSe/ZnS quantum dots; Molecular chaperone; Polarization modulation;
Alpha casein micelles show not only molecular chaperone-like aggregation inhibition properties but also protein refolding activity from the denatured state
Keywords: چاپرون مولکولی; BSA; bovine serum albumin; CAB; bovine carbonic anhydrase; LYZ; lysozyme; CMC; critical micellar concentration; oval; ovalbumin; ANS; 8-anilino-1-naphtalene-sulfonic acid; Casein; Hydrophobicity; Molecular chaperone; Protein refolding;
Effects of cytoplasmic and periplasmic chaperones on secretory production of single-chain Fv antibody in Escherichia coli
Keywords: چاپرون مولکولی; Single-chain variable fragment; Molecular chaperone; Secretory production; Periplasm; Extracellular production
Use of yeast as a system to study amyloid toxicity
Keywords: چاپرون مولکولی; Amyloid; Rnq1; Prion; Molecular chaperone; Yeast; Proteotoxicity;
Co-expression of the Plasmodium falciparum molecular chaperone, PfHsp70, improves the heterologous production of the antimalarial drug target GTP cyclohydrolase I, PfGCHI
Keywords: چاپرون مولکولی; Molecular chaperone; Plasmodium falciparum; Hsp70; GTP cyclohydrolase I; Co-expression; Protein folding;
Cytoplasmic production of soluble and functional single-chain Fv-Fc fusion protein in Escherichia coli
Keywords: چاپرون مولکولی; Single-chain variable fragment; Fc fusion protein; Molecular chaperone; GroELS; Soluble production; Escherichia coli;
1-Deoxy-d-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines
Keywords: چاپرون مولکولی; Iminoalditol; N-Alkylation; Galactosidase inhibitor; Molecular chaperone; GM1-gangliosidosis;
Effects of co-expression of molecular chaperones on heterologous soluble expression of the cold-active lipase Lip-948
Keywords: چاپرون مولکولی; Cold-active lipase; Molecular chaperone; Co-expression; Soluble expression
Distinct interactions of αA-crystallin with homologous substrate proteins, δ-crystallin and argininosuccinate lyase, under thermal stress
Keywords: چاپرون مولکولی; αA-Crystallin; Molecular chaperone; Goose δ-crystallin; Argininosuccinate lyase; Thermal stability; Protein aggregateASL, argininosuccinate lyase; ANS, 1-anilinonaphthalene-8-sulfonic acid; CD, circular dichroism; Tm, transition mid-point temperature; N-1
Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones
Keywords: چاپرون مولکولی; Aggregation; Molecular chaperone; Neurodegenerative disease; Polyglutamine; Protein folding;
Effect of CCS on the accumulation of FALS SOD1 mutant-containing aggregates and on mitochondrial translocation of SOD1 mutants: Implication of a free radical hypothesis
Keywords: چاپرون مولکولی; CCS; FALS SOD1; Mitochondrial translocation of SOD1 mutants; Macroautophagy; Molecular chaperone; Oxidative stress
Curcumin-induced inhibition of proteasomal activity, enhanced HSP accumulation and the acquisition of thermotolerance in Xenopus laevis A6 cells
Keywords: چاپرون مولکولی; Heat shock proteins; Proteasomal inhibition; Heat shock factor; Amphibian; Confocal microscopy; Molecular chaperone;
The chaperone action of bovine milk αS1- and αS2-caseins and their associated form αS-casein
Keywords: چاپرون مولکولی; αS-Casein; Chaperone action; Molecular chaperone; Milk protein
The Four Hydrophobic Residues on the Hsp70 Inter-Domain Linker Have Two Distinct Roles
Keywords: چاپرون مولکولی; molecular chaperone; Hsp70; Hsp40; allosteric coupling; protein foldingHsp70, 70-kDa heat shock protein; Hsp40, 40-kDa heat shock protein; NBD, nucleotide binding domain; SBD, substrate binding domain; NEF, nucleotide exchange factor; SPR, surface plasmon
Hyperthermophilic archaeal prefoldin shows refolding activity at low temperature
Keywords: چاپرون مولکولی; PhPFD; prefoldin from Pyrococcus horikoshii OT3; TEM; transmission electron microscopy; Molecular chaperone; Prefoldin; Refolding activity; Lysozyme; Interaction study; Surface plasmon resonance;
1-Deoxynojirimycins with dansyl capped N-substituents as probes for Morbus Gaucher affected cell lines
Keywords: چاپرون مولکولی; Iminoalditol; N-Alkylation; Glucosidase inhibitor; Molecular chaperone; Gaucher’s disease
Functional expression of single-chain Fv antibody in the cytoplasm of Escherichia coli by thioredoxin fusion and co-expression of molecular chaperones
Keywords: چاپرون مولکولی; Single-chain antibody; Soluble expression; Thioredoxin fusion; Molecular chaperone
BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion
Keywords: چاپرون مولکولی; BAG, Bcl-2-associated athanogene; PDZGEF2, PDZ domain containing guanine nucleotide exchange factor 2Hsp70; Molecular chaperone; Rap1; Guanine nucleotide exchange factor; WW domain; Cell adhesion
Chaperonin-encapsulation of proteins for NMR
Keywords: چاپرون مولکولی; NMR, nuclear magnetic resonance; HSQC, heteronuclear single quantum coherence; SR398, single-ring mutant of GroEL with ATPase deficient mutation D398A; SBP, strongly binding peptide to GroELAggregation; NMR; Molecular chaperone; GroE; Protein encapsulatio
Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies
Keywords: چاپرون مولکولی; Reactive nitrogen species; S-Nitrosylation; Molecular chaperone; Ubiquitin-proteasome system; Protein misfolding; Mitochondrial fission; Neurodegeneration; Memantine
Hsp70- and Hsp90-mediated proteasomal degradation underlies TPIsugarkill pathogenesis in Drosophila
Keywords: چاپرون مولکولی; Molecular chaperone; TPI deficiency; Triosephosphate isomerase; Glycolytic enzymopathy; Drosophila;
A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90α/β
Keywords: چاپرون مولکولی; RAD, radicicol; GdA, geldanamycin; 17-AAG, 17-allylamino-demethoxygeldanamycin; DMSO, dimethylsulphoxide; 5-FOA, 5-fluoroorotic acidHsp90; Molecular chaperone; Cancer; Drug target; Drug resistance; Yeast
Identification of Residues on Hsp70 and Hsp90 Ubiquitinated by the Cochaperone CHIP
Keywords: چاپرون مولکولی; CHIP, C-terminus of Hsc70 interacting protein; TPR, tetratricopeptide repeat; LC–MS/MS, liquid chromatography–tandem mass spectrometry; βME, β-mercaptoethanolubiquitin; protein turnover; tandem mass spectrometry; molecular chaperone; C-terminus of Hsc70 i
Molecular cloning of calnexin and calreticulin in the Pacific oyster Crassostrea gigas and its expression in response to air exposure
Keywords: چاپرون مولکولی; Bivalve; Endoplasmic reticulum; Hypoxia; Molecular chaperone; Mollusk
The Hsp70 chaperones of the Tritryps are characterized by unusual features and novel members
Keywords: چاپرون مولکولی; Heat shock proteins; Hsp40; Hsp70; Kinetoplastid; Molecular chaperone; Trypanosome
Targeted therapeutic approaches for hormone-refractory prostate cancer
Keywords: چاپرون مولکولی; Hormone-refractory prostate cancer; Targeted therapy; Vitamin D analogues; Angiogenesis inhibitors; Endothelin receptor antagonists; Apoptotic pathways; Molecular chaperone; Tyrosine kinase inhibitors; Immunotherapy
A quantitative NMR spectroscopic examination of the flexibility of the C-terminal extensions of the molecular chaperones, αA- and αB-crystallin
Keywords: چاپرون مولکولی; small heat-shock protein; molecular chaperone; NMR Spectroscopy; C-terminal extension; site directed mutagenesis; DTT; dithiothreitol; HSQC; Heteronuclear Single Quantum Coherence; IPTG; isopropyl-1-thio-β-d-galactopyranoside; LB; Luria-Bertani; NMR; Nuc
Mechanism of suppression of dithiothreitol-induced aggregation of bovine α-lactalbumin by α-crystallin
Keywords: چاپرون مولکولی; DLCA; diffusion-limited cluster-cluster aggregation; DLS; dynamic light scattering; DTT; dithiothreitol; RLCA; reaction-limited cluster-cluster aggregation; α-Crystallin; α-Lactalbumin; Aggregation; Molecular chaperone; Dynamic light-scattering;
Target molecules of molecular chaperone (HSP70 family) in injured gastric mucosa in vivo
Keywords: چاپرون مولکولی; Heat shock protein; HSP70; Molecular chaperone; Actin; Myosin; Stomach
Interaction of Hsp70 with p49/STRAP, a serum response factor binding protein
Keywords: چاپرون مولکولی; Molecular chaperone; Co-chaperone; Protein–protein interaction; Serum response factor; Hsp70; Hsp40; p49/STRAP; SRFBP1
Jid1 is a J-protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation
Keywords: چاپرون مولکولی; Molecular chaperone; ERAD; Mitochondria; Protein translocation; Endoplasmic reticulum; Yeast
Interaction of chaperone α-crystallin with unfolded state of α-amylase: Implications for reconstitution of the active enzyme
Keywords: چاپرون مولکولی; ANS, 8-anilinonaphthalene sulphonate; BSA, bovine serum albumin; DNS, dinitrosalicylic acid; DTT, dithiothreitol; GdnHCl, guanidine hydrochlorideα-Amylase; α-Crystallin; Molecular chaperone
The role of molecular chaperones in human misfolding diseases
Keywords: چاپرون مولکولی; Hsp; heat shock protein; polyQ; polyglutamine; TRiC; TCP-1 Ring Complex; CCT; chaperonin containing TCP-1; Molecular chaperone; Protein misfolding; Heat shock protein; Neurodegeneration;
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum
Keywords: چاپرون مولکولی; Molecular chaperone; Hsp70; Hsp40; J domain; ATPase; Pyrimidinone
Characterisation of mutations in GroES that allow GroEL to function as a single ring
Keywords: چاپرون مولکولی; Molecular chaperone; Chaperonin; Protein folding; GroEL; GroES
cDNA cloning and expression of grp94 in the Pacific oyster Crassostrea gigas
Keywords: چاپرون مولکولی; Crassostrea gigas; Endoplasmic reticulum (ER); GRP94; Hypoxia; Molecular chaperone; Mollusk; Oyster;
Simultaneous exposure of Xenopus A6 kidney epithelial cells to concurrent mild sodium arsenite and heat stress results in enhanced hsp30 and hsp70 gene expression and the acquisition of thermotolerance
Keywords: چاپرون مولکولی; Heat shock proteins; Sodium arsenite; Heat shock; Heat shock factor; Thermotolerance; Confocal microscopy; Molecular chaperone
Chaperone over-expression in Escherichia coli: Apparent increased yields of soluble recombinant protein kinases are due mainly to soluble aggregates
Keywords: چاپرون مولکولی; Protein kinases; Escherichia coli; Molecular chaperone; Protein folding; Co-expression; Protein purification
Examination of cadmium-induced expression of the small heat shock protein gene, hsp30, in Xenopus laevis A6 kidney epithelial cells
Keywords: چاپرون مولکولی; Heat shock protein; Cadmium chloride; Thermotolerance; Gene expression; mRNA; Confocal microscopy; Molecular chaperone
Differential cell death regulation between adult-unloaded and aged rat soleus muscle
Keywords: چاپرون مولکولی; Sarcopenia; Caspase-3; Mitochondrial membrane permeability; ER stress; Molecular chaperone
Knockdown of the co-chaperone Hop promotes extranuclear accumulation of Stat3 in mouse embryonic stem cells
Keywords: چاپرون مولکولی; mESC; RNAi; Heat shock protein; Molecular chaperone; Hsp90; Phosphorylation
The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding
Keywords: چاپرون مولکولی; Hsp70; Molecular chaperone; Nucleotide exchange factor; Fluorescence; ATPase
Isofagomine increases lysosomal delivery of exogenous glucocerebrosidase
Keywords: چاپرون مولکولی; Pharmacological chaperone; Gaucher disease; Lysosomal storage disorders; Glucocerebrosidase; Molecular chaperone; Molecular mechanisms of pharmacological action; Enzyme replacement therapy