دانلود مقالات ISI درباره Mptp + ترجمه فارسی

Mitochondrial swelling and microtubule depolymerization are associated with energy depletion in axon degeneration

Keywords: DIV; day in vitro; EGTA; ethylene glycol tetraacetic acid; mPTP; mitochondrial permeability transition pore; NAD; nicotinamide adenine dinucleotide; Nmnat; nicotinamide mononucleotide adenylyltransferase; PBS; phosphate-buffered saline; TBS; Tris-buffered

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Comparison of motor performance, brain biochemistry and histology of two A30P α-synuclein transgenic mouse strains

Keywords: aSyn; α-synuclein; ANOVA; analysis of variance; DOPAC; 3,4-dihydroxyphenylacetic acid; DA; dopamine; HVA; homovanillic acid; 5-HT; 5-hydroxytryptamine; 6-OHDA; 6-hydroxydopamine; LB; Lewy bodies; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PFA; p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

NRSF/REST neuronal deficient mice are more vulnerable to the neurotoxin MPTP

Keywords: NRSF/REST; Neuronal conditional knockout; MPTP; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

Keywords: DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; DPBS; Dulbecco's phosphate-buffered saline; EDTA; ethylenediaminetetraacetic acid; FCS; foetal calf serum; GFAP; glial fibrillary acid protein; IL; interleukin; LDH; lactate dehydrogena

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

ATP-ases of synaptic plasma membranes in striatum: Enzymatic systems for synapses functionality by in vivo administration of l-acetylcarnitine in relation to Parkinson's Disease

Keywords: AChE; acetylcholinesterase; AD; Alzheimer's Disease; ANOVA; analysis of variance; AP; action potentials; DTNB; 5,5′-dithiobis-(2-nitrobenzoic acid); EDTA; ethylenediamine tetraacetic acid; EGTA; ethylene glycol tetraacetic acid; HEPES; 4-(2-hydroxyeth

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators

Keywords: 6-OHDA; 6-hydroxydopamine; ALS; amyotrophic lateral sclerosis; AD; Alzheimer's disease; BBB; blood-brain barrier; DFO; desferrioxamine; EGCG; epigallocatechin 3-gallate; EPO; erythropoietin; FBXL5; F-box/leucine-rich repeat protein 5, GLUT, glucose tran

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Telmisartan attenuates MPTP induced dopaminergic degeneration and motor dysfunction through regulation of α-synuclein and neurotrophic factors (BDNF and GDNF) expression in C57BL/6J mice

Keywords: MPTP; Telmisartan; Motor function; α-synuclein; BDNF; GDNF; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; BDNF; brain derived neurotrophic factor; GDNF; glial derived neurotrophic factor; TEL; Telmisartan; AT1R; angiotensin type 1 receptor; PD; Par

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats

Keywords: ·OH; hydroxyl radical; 6-OHDA; 6-hydroxydopamine; BN-PAGE; blue native-polyacrylamide gel electrophoresis; DA; dopamine; DHBA; dihydroxybenzoic acid; EDTA; ethylenediamine tetraacetic acid; ETC; electron transport chain; GSH; reduced glutathione; GSSG; o

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Research ReportEffects of the neurotoxin MPTP and pargyline protection on extracellular energy metabolites and dopamine levels in the striatum of freely moving rats

Keywords: In vivo microdialysis; MPTP; Pargyline; Dopamine; Energy metabolism; Glucose; Lactate; Pyruvate;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Organelle plasticity and interactions in cholesterol transport and steroid biosynthesis

Keywords: cAMP; cyclic AMP; ACAT; acyl-CoA cholesterol acyltransferase; ACSL4; acyl-CoA synthetase 4; ANT; adenine nucleotide transporter; BN-PAGE; blue native polyacrylamide gel electrophoresis; CPT; carnitine palmitoyltransferase; ER; endoplasmic reticulum; ETC;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: Differential activation of stress and survival pathways

Keywords: β-AR; β-adrenergic receptors; ANOVA; analysis of variance; BSA; bovine serum albumin; cAMP; cyclic-AMP; DAPI; 4′,6-diamidino-2-phenylindole; ΔΨ; mitochondrial transmembrane electric potential; DHE; dihydroethidium; DMEM; Dulbecco's-modified eagle's

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Minocycline, levodopa and MnTMPyP induced changes in the mitochondrial proteome profile of MPTP and maneb and paraquat mice models of Parkinson's disease

Keywords: PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Maneb; manganese ethylene-bis-dithiocarbamate; Paraquat; N,N′-dimethyl-4,4′-bipyridinium dichloride; MnTMPyP; manganese (III) tetrakis (1-methyl-4-pyridyl) porphyrin; Mn-SOD;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Advances in thin tissue Golgi-Cox impregnation: Fast, reliable methods for multi-assay analyses in rodent and non-human primate brain

Keywords: 3-D; 3-dimensional; 6-OHDA; 6-hydroxydopamine; ABC; avidin biotin peroxidase complex; BrdU; bromodeoxyuridine; DA; dopamine; D1R; dopamine D1 receptor; D2R; dopamine D2 receptor; DAB; 3,3′-diaminobenzidine tetrahydrochloride; DMSO; dimethyl sulfoxide; E

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Implication of GPER1 in neuroprotection in a mouse model of Parkinson's disease

Keywords: GPER1; 17β-estradiol; MPTP; Neuroprotection; Dopamine; Striatum; Substantia nigra;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of dopamine D3 receptor in the striatal regions and substantia nigra in diffuse Lewy body disease

Keywords: ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; CDR; Clinical Dementia Rating; DAT; dopamine transporter; DLB; dementia with Lewy bodies; DLBD; diffuse Lewy body disease; LBs; Lewy bodies; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropy

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Attenuation of MPTP/MPP+ toxicity in vivo and in vitro by an 18-mer peptide derived from prosaposin

Keywords: ALT; alanine transaminase; anti-GFAP; anti-glial fibrillary acidic protein; AST; aspartate transaminase; BSA; bovine serum albumin; BUN; blood urea nitrogen; Cr; creatinine; DA; dopamine; DAPI; 4′-6-diamidino-2-phenylindole; DAT; dopamine transporter; D

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2013 سفارش ترجمه

Lipophilic adamantyl- or deferasirox-based conjugates of desferrioxamine B have enhanced neuroprotective capacity: implications for Parkinson disease

Keywords: BBB; blood-brain barrier; BSO; L-buthionine sulfoximine; CQ; clioquinol; DFOB; desferrioxamine B; FAC; ferric ammonium citrate; ICP-MS; inductively coupled plasma-mass spectrometry; MAO; monoamine oxidase; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydrop

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2013 سفارش ترجمه

Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons

Keywords: ALS; amyotrophic lateral sclerosis; AMPA; α-amino-5-methyl-3-hydroxyisoxazolone-4-propionat; CaBP; calcium binding proteins; CPA; cyclopiazonic acid; CsA; cyclosporine A; eIF2α; eukaryotic translation initiation factor 2 α; EMD; earth mover's distance;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2013 سفارش ترجمه

The sources of salidroside and its targeting for multiple chronic diseases

Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid protein; MPTP; 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine; MPP+; N-methyl-4-phenylpyridine; AD; Alzheimer's disease; PD; Parkinson's disease; STZ; streptozotocin; PI3K; phosphatidylinositol 3-kinase; ROS; react

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2020 سفارش ترجمه

Alpha-synuclein overexpression induced mitochondrial damage by the generation of endogenous neurotoxins in PC12 cells

Keywords: PD; Parkinson's disease; salsolinol; 1-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline; NM-salsolinol; 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolin; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahy-dropyridine; α-Synuclein; Salsolinol; NM-salsolinol;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Neuronal or inducible nitric oxide synthase (NOS) expression level is not involved in the different susceptibility to nigro-striatal dopaminergic neurotoxicity induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) between C57BL/6 and BALB/c mice

Keywords: BALB/c mice; C57BL/6 mice; iNOS; MPP+; MPTP; nNOS; Strain difference

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Motor behavior correlates with striatal [18F]-DOPA uptake in MPTP-lesioned primates

Keywords: MPTP; Parkinson’s disease; Primates; [18F]-F-DOPA; PET; Movement disorders

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Different susceptibility to 1-methyl-4-phenylpyridium (MPP+)-induced nigro-striatal dopaminergic cell loss between C57BL/6 and BALB/c mice is not related to the difference of monoamine oxidase-B (MAO-B)

Keywords: ALB/c mice; C57BL/6 mice; Intracerebroventricular injection; MPP+; MPTP; Strain difference

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of human interleukin-10 on the expression of nitric oxide synthases in the MPTP-based model of Parkinson's disease

Keywords: Parkinson's disease; MPTP; nitric oxide synthase; nNOS; iNOS; viral vector; IL-10

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Resistance of the golden hamster to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-neurotoxicity is not only related with low levels of cerebral monoamine oxidase-B

Keywords: Monoamine oxidase-B; Golden hamster; MPTP; MPP+; Tyrosine hydroxylase (TH)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The adenosine A2A antagonistic properties of selected C8-substituted xanthines

Keywords: Adenosine A2A receptors; Antagonism; Xanthine; Haloperidol-induced catalepsy; Parkinson's disease; CNS; central nervous system; CPA; cyclopentyladenosine; CSC; (E)-8-(3-chlorostyryl)caffeine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EDAC; N

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease

Keywords: Lactadherin; MFGE8; Dopaminergic neurons; Phagocytosis; Neurodegenerative disease; MPTP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

African eggplant (Solanum anguivi Lam.) fruit with bioactive polyphenolic compounds exerts in vitro antioxidant properties and inhibits Ca2+-induced mitochondrial swelling

Keywords: Solanum anguivi fruit; Antioxidant activity; Oxidative stress; Mitochondrial swelling; HPLC; Polyphenolic compounds; MPTP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Potential neuroprotective effect of ibuprofen, insights from the mice model of Parkinson's disease

Keywords: MPTP; neuroinflammation; neurodegeneration; ibuprofen; α-synuclein; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Gremlin is a novel VTA derived neuroprotective factor for dopamine neurons

Keywords: Gremlin; MPTP; VEGF receptor; Ventral tegmental area; Dopamine; Parkinson’s disease

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Protective effects of lycopene against methylmercury-induced neurotoxicity in cultured rat cerebellar granule neurons

Keywords: MeHg; methylmercury; ROS; reactive oxygen species; mtDNA; mitochondrial DNA; THF; tetrahydrofuran; BHT; butylated hydroxytoluene; CCK-8; cell counting kit-8; mPTP; mitochondrial permeability transition pore; DCFH-DA; dichlorofluorescein diacetate; NRFU; n

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Rotenone-induced neurotoxicity in rat brain areas: A study on neuronal and neuronal supportive cells

Keywords: ANOVA; one way analysis of variance; BSA; bovine serum albumin; DMSO; dimethyl sulphoxide; EDTA; ethylenediamine tetraacetic acid; GFAP-ir; glial fibrillary acidic protein immunoreactivity; IF; immunofluorescence; ir; immunoreactivity; MB; mid brain; LPS;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Antioxidant potential of melatonin enhances the response to L-dopa in 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine-parkinsonian mice

Keywords: L-dopa; melatonin; mice; MPTP; oxidative stress; Parkinson's disease; wearing off

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of Oxidative Alcohol Metabolism on the Mitochondrial Permeability Transition Pore and Necrosis in a Mouse Model of Alcoholic Pancreatitis

Keywords: Tissue Damage; Ethanol Toxicity; Cell Death; Exocrine Pancreas; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; ATP; adenosine triphosphate; BAL; blood alcohol level; [Ca2+]i; free cytosolic Ca2+; CCK; cholecystokinin-8; CypD; cyclophilin D; ΔÎ

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Neurorestoration by physical exercise: Moving forward

Keywords: BDNF; GDNF; Exercise; Monkey model; MPTP; Neurotrophic factors

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on retinal dopaminergic system in mice

Keywords: Retina; Methamphetamine; MPTP; Dopamine; Neurotoxicity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

CommentaryIn search of the neuroprotective mechanism of thiazolidinediones in Parkinson's disease

Keywords: MPTP; MPP+; Glitazones; Oxidative stress; PPAR gamma;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neuroblastic apoptosis in the subventricular zone is caused by 1-methy-4-phenylpiridinium (MPP+) converted from MPTP through MAO-B

Keywords: Intracerebroventricular (icv) injection; Monoamine oxidase-B (MAO-B); MPP+; MPTP; Neuroblastic apoptosis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP+, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells

Keywords: [Ca2+]i; intracellular calcium concentration; DAT; dopamine transporter; DBH; dopamine-β-hydroxylase; DCFH-DA; 2,7-dichlorofluorescein diacetate; DMEM/F-12; Dulbecco's modified eagle medium nutrient mixture F-12; DMSO; dimethyl sulfoxide; FBS; fetal bovi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Non-human primate FOG develops with advanced parkinsonism induced by MPTP Treatment

Keywords: Freezing of gait; MPTP; Animal model; Non-human primate; Dopamine;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Dangguijakyak-san protects dopamine neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity under postmenopausal conditions

Keywords: Dangguijakyak-san; Neuroprotection; MPTP; Postmenopause;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Imidazopyridazinones as novel PDE7 inhibitors: SAR and in vivo studies in Parkinson's disease model

Keywords: PDE7; Imidazopyridazinone; CNS penetration; Parkinson's disease; MPTP; Haloperidol;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Asiaticoside: Attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism via maintaining redox balance and up-regulating the ratio of Bcl-2/Bax

Keywords: PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SN; substantia nigra; DA; dopamine; MDA; malonyldialdehyde; GSH; reduced glutathione; qRT-PCR; quantitative real-time polymerase chain reaction; DOPAC; 3, 4-dihydroxyphenylacetic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

Keywords: ANT; adenine nucleotide translocase; BKA; bongkrekic acid; CAT; carboxyatractyloside; CRC; calcium retention capacity; CsA; cyclosporine A; CyP-D; cyclophilin-D; PEG; poly(ethylene glycol); IMM; inner mitochondrial membrane; MPT; mitochondrial permeabilit

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Astrocyte-specific IKK2 activation in mice is sufficient to induce neuroinflammation but does not increase susceptibility to MPTP

Keywords: Neuroinflammation; IKK2; NF-κB; Astrocytes; MPTP; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Clavulanic acid inhibits MPP+-induced ROS generation and subsequent loss of dopaminergic cells

Keywords: Clavulanic acid; MPTP; Neuroprotection; Parkinson’s disease (PD); Mitochondria; Apoptosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Atrial natriuretic peptide prevents the mitochondrial permeability transition pore opening by inactivating glycogen synthase kinase 3β via PKG and PI3K in cardiac H9c2 cells

Keywords: ANP; GSK-3β; mPTP; PKG; PI3K; Reperfusion injury

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Preconditioning the hyperlipidemic myocardium: Fact or fantasy?

Keywords: I/R; ischemia-reperfusion; FWOP; first window of protection; SWOP; second window of protection; TWOP; third window of protection; BH4; tetrahydrobiopterin; eNOS; endothelial nitric oxide synthase; TNF-α; tumor necrosis factor-α; MAPK; mitogen-activate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Healing the diabetic heart: Does myocardial preconditioning work?

Keywords: I/R; Ischemia-reperfusion; TNF-α; Tumor necrosis factor-alpha; IPC; Ischemic preconditioning; FWOP; First window of protection; SWOP; Second window of protection; TWOP; Third window of protection; eNOS; Endothelial nitric oxide synthase; NO; Nitric oxi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacological and Biochemical Interventions of Cigarette Smoke, Alcohol, and Sexual Mating Frequency on Idiopathic Rat Model of Parkinson's Disease

Keywords: Dopamine; mitochondria; MPTP; nigrostriatal pathway;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه