دانلود مقالات ISI درباره Mtor + ترجمه فارسی

The role of amino acid transporters in GSH synthesis in the blood-brain barrier and central nervous system

Keywords: AA; amino acid; AARE; amino acids response elements; ApN; aminopeptidase N; ARE; antioxidant response element; BBB; blood-brain barrier; BEC; brain endothelial cell; CNS; central nervous system; CSF; cerebrospinal fluid; EC; endothelial cell; ERK; extra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Exercise modulates microRNAs that affect the PTEN/mTOR pathway in rats after spinal cord injury

Keywords: microRNA; Regeneration; Target gene expression; Activity-dependent plasticity; PTEN; mTOR; Spinal cord injury;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Autoimmunity, Intestinal Lymphoid Hyperplasia, and Defects in Mucosal B-Cell Homeostasis in Patients With PTEN Hamartoma Tumor Syndrome

Keywords: Bannayan Riley Ruvalcaba Syndrome; Cowden Syndrome; Hamartoma Tumor Syndrome; GC; germinal center; Ig; immunoglobulin; MALT; mucosa-associated lymphoid tissue; mTOR; mammalian target of rapamycin; PHTS; PTEN hamartoma tumor syndrome; PI3K; phosphoinositol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8

Keywords: mTOR; LST8; Raptor; Rictor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat

Keywords: Hepatic progenitor cells; Liver regeneration; Liver injury; mTOR; Hepatocellular carcinoma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

ReviewAre there opportunities for chemotherapy in the treatment of hepatocellular cancer?

Keywords: Resistance; Chemotherapy; mTOR; Hypoxia; Hepatocellular; Doxorubicin; Sorafenib;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Oncology/EndocrineAkt/mTOR signaling pathway is crucial for gemcitabine resistance induced by Annexin II in pancreatic cancer cells

Keywords: Annexin II; Pancreatic cancer; Gemcitabine; Akt; mTOR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperInhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation

Keywords: ischemia; rapamycin; 3-methyladenine; apoptosis; necrosis; autophagy; ANOVA; analysis of variance; HI; hypoxia-ischemia; mTOR; mammalian target of rapamycin; PARP; poly (ADP-ribose) polymerase; PI; propidium iodide; PN; postnatal; RAP; rapamycin; TUNEL; t

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway

Keywords: Autophagy; GADD34; TSC; mTOR; Cell death; HDACC, Acetyl-CoA carboxylase; AMPK, AMP-activated protein kinase; ATF4, activating transcription factor 4; Bcl-2, B-cell CLL/lymphoma 2; CHOP, CCAAT/enhancer binding protein (C/EBP) homologous protein also called

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma

Keywords: Temsirolimus; mTOR; Child; Adolescent; Glioma; Neuroblastoma; Rhabdomyosarcoma; Clinical trial; Phase II;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Management of indolent lymphoma: Where are we now and where are we going

Keywords: Indolent lymphoma; Non-Hodgkin; Follicular; Marginal zone; Small lymphocytic; Rituximab; CD20; Cyclophosphamide; Doxorubicin; Bendamustine; Fludarabine; Lenalidomide; Bortezomib; PI3K; mTOR; Bruton's tyrosine kinase; Histone deacetylase inhibitors

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Keywords: BCA; bicinchoninic acid protein; ECL; enhanced chemiluminescence; IR; insulin receptor; mTOR; mammalian target of rapamycin; mTORC1; mammalian target of rapamycin complex 1; mTORC2; mammalian target of rapamycin complex 2; NODAT; new onset diabetes after

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats

Keywords: DAG; des-acyl ghrelin; GHS-R1a; growth hormone secretagogue receptor 1a; GHRP-2; growth hormone releasing peptide 2; GSK3β; glycogen synthase kinase-3 beta; IGF-I; insulin-like growth factor 1; IL-6; interleukin-6; MAFbx; muscle atrophy F-box protein/atr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The role of AMPK/mTOR/S6K1 signaling axis in mediating the physiological process of exercise-induced insulin sensitization in skeletal muscle of C57BL/6 mice

Keywords: 4E-BP1; Initiation factor 4E-binding protein 1; ACC; Acetyl-CoA carboxylase; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; CPT1; Carnitine palmitoyltransferase I; DAG; Diacylglycerol; FAT/CD36; Fatty acid translocase; LCFA; Long-chain fatty a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Relationship between 18F-FDG uptake on positron emission tomography and molecular biology in malignant pleural mesothelioma

Keywords: 18F-FDG PET; Mesothelioma; Glut1; Hypoxia; mTOR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Role of mTOR in neuroprotection and axon regeneration after inflammatory stimulation

Keywords: Lens injury; CNTF; LIF; Axon regeneration; Retina; mTOR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Beclin 1-mediated autophagy in hepatocellular carcinoma cells: Implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling

Keywords: Beclin 1; Autophagy; Hepatocellular carcinoma cells; mTOR; Oroxylin A;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response

Keywords: PGC 1 beta; Endoplasmic reticulum stress; Mitochondria; mTOR; Amino acids; Brain;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones

Keywords: Breast; Letrozole; Resistance; AKT; mTOR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Understanding of the roles of phospholipase D and phosphatidic acid through their binding partners

Keywords: AMPK; AMP-activated protein kinase; ARF; ADP-ribosylation factor; CDK5; cyclin-dependent kinase 5; CEM; caveolin-enriched membrane; CRMP-2; collapsin response mediator protein-2; EGF; epidermal growth factor; EGFR; EGF receptor; GAP; GTPase-activating pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells

Keywords: Sulforaphane; Prostate cancer; mTOR; S6K1; Protein synthesis; Survivin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Immunohistochemical Analysis of the Akt/mTOR/4E-BP1 Signalling Pathway in Canine Haemangiomas and Haemangiosarcomas

Keywords: Akt; dog; haemangiosarcoma; mTOR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Leucine limitation regulates myf5 and myoD expression and inhibits myoblast differentiation

Keywords: Leucine; Myoblast; Differentiation; myf5; myoD; mTOR; GCN2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy

Keywords: Cancer therapy; Regrowth resistance; PI3K; mTOR; NVP-BEZ235

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes

Keywords: PA, phosphatidic acid; PC, phosphatidylcholine; PEt, phosphatidylethanol; PLD, phospholipase D; mTOR, mammalian target of rapamycin; S6K, p70S6 kinasePodocytes; Shear stress; Apoptosis; c-Src; Phospholipase D; mTOR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin

Keywords: Cortical development; mTOR; mTORC1; mTORC2; Neural progenitor cell; Radial glia;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

The role of pseudokinases in cancer

Keywords: ALL; Acute Lymphoblastic Leukaemia; AML; Acute Myeloid Leukaemia; AMPK; 5′-Adenosine Monophosphate Activated Protein Kinase; ATF4; Activating Transcriptional Factor 4; ATP; Adenosine-5′-Triphosphate; BTICs; Brain Tumour-Initiating Cells; C/EBPα; CCAA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis

Keywords: CIA; CD4 T cells; mTOR; MAPK; Activation pathways; Combination therapy;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Spinal Cord NMDA Receptor-Mediated Activation of Mammalian Target of Rapamycin Is Required for the Development and Maintenance of Bone Cancer-Induced Pain Hypersensitivities in Rats

Keywords: mTOR; NMDA receptors; activation; dorsal horn; cancer pain

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanistic mammalian target of rapamycin (MTOR) cell signaling: Effects of select nutrients and secreted phosphoprotein 1 on development of mammalian conceptuses

Keywords: MTOR; Secreted phosphoprotein 1; Amino acids; Glucose; Conceptus; Pregnancy; Endocrine disruptor; Uterus;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

DISC1-binding proteins in neural development, signalling and schizophrenia

Keywords: DISC1; Schizophrenia; Neurodevelopment; Signalling; Synapse; Association studies; APP; Amyloid precursor protein; ATF4; Activating transcription factor 4; BACE1; β-site APP-cleaving enzyme-1; BBS4; Bardet-Biedl syndrome 4; CEP290; Centrosomal protein 2

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

Keywords: 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindolacetic acid; AD; Alzheimer's disease; DA; Dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; EPI; Epinephrine; HPLC; high performance liquid chromatography; HVA; homovanillic acid; LTD; long-term depression

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Second basic pockets contribute to the localization of PX domains by binding to phosphatidic acid

Keywords: class III PI3K; class III phosphatidylinositol 3-kinase (E.C.2.7.1.137); DGK; diacylglycerol kinase (E.C.2.7.1.107); DMEM; Dulbecco's modified Eagle's Medium; EEA1; early endosomal antigen 1; ENTH; epsin N-terminal homologue; FYVE; Fab1p/YOTP/Vac1p/EE

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Long-term Medical Management of the Liver Transplant Recipient: What the Primary Care Physician Needs to Know

Keywords: ACEi; angiotensin converting enzyme inhibitor; ARB; angiotensin receptor blocker; CKD; chronic kidney disease; CNI; calcineurin inhibitor; IBD; inflammatory bowel disease; LT; liver transplant; MMF; mycophenolate mofetil; mTOR; mammalian target of rapamyc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma

Keywords: HCC, hepatocellular carcinoma; mTOR, mammalian target of rapamycin; 4E-BP1, eIF4E binding protein; MVD, microvessel density; MDR, multi-drug resistant geneHepatocellular carcinoma; mTOR; Microtubule; Sustained antitumor activity; Anti-apoptotic/survival p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Proteogenomics of synaptosomal mitochondrial oxidative stress

Keywords: Synaptosome; Mitochondria; Sod2; Oxidative stress; mTOR; Free radicals

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Stem cells as the root of pancreatic ductal adenocarcinoma

Keywords: ABC; ATP binding cassette; ALDH1; Aldehyde dehydrogenase 1a1; Arx; Aristalless-related homeobox; EMT; Epithelial-to-mesenchymal transition; CAC; Centroacinar cells; CD; Cluster of differentiation; CDKN2A; Cyclin-dependent kinase inhibitor 2A; CSC; Cancer

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence

Keywords: mTOR; SIRT1; Mesangial cells; Senescence; High glucose

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

Keywords: Chemoprevention; Colon Cancer; Oncogene; Tumor Suppressor; ACC; acetyl-CoA carboxylase; ADP; adenosine diphosphate; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; CRC; colorectal cancer; eIF4E; eukaryotic translatio

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo

Keywords: Amino acids; Blastocyst activation; Implantation; mTOR;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats

Keywords: ANOVA; analysis of variance; DV; doros-ventral; EDTA; ethylenediaminetetraacetic acid; EEG; electroencephalography; GP; globus pallidus; KCC2; potassium-chloride cotransporter 2; mTOR; mammalian target of rapamycin; NMDA; N-methyl-D-aspartate; PTEN; phosp

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Campylobacter jejuni Induces Colitis Through Activation of Mammalian Target of Rapamycin Signaling

Keywords: Crypt Abscesses; Imaging; Mouse Model; Immune Response; Signal Transduction; CFU; colony-forming unit; EGFP; enhanced green fluorescent protein; FISH; fluorescence in situ hybridization; IL; interleukin; MLN; mesenteric lymph node; mTOR; mammalian target

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Autophagy and polyglutamine diseases

Keywords: HD; Huntington's disease; SCA; spinocerebellar ataxia; DRPLA; Denatorubral-pallidoluysian atrophy; SBMA; spinal and bulbar muscular atropy; Htt; Huntingtin; UPS; ubiquitin-proteasome system; HDL-2; Huntington's disease-like 2; IBs; inclusion bodies; RNA

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Neuroglialpharmacology: Myelination as a shared mechanism of action of psychotropic treatments

Keywords: White matter; Oligodendrocyte; Intracortical myelin; Medication; MRI; NG2 cells; Neuregulin; ErbB; DISC1; IGF1; Reelin; Cdk; MAPK; mTOR; Leptin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Redox-regulating role of insulin: The essence of insulin effect

Keywords: 4-HNE; 4-hydroxynonenal; 8-OHdG; 8-hydroxydeoxyguanosine; 8-OHG; 8-hydroxyguanine; 8-iso-PGF2α; 8-iso-prostaglandin F2α; AD; Alzheimer's disease; AIDS; acquired immunodeficiency syndrome; Akt; protein kinase B; AMI; acute myocardial infarction; APS; a

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Autophagy Attenuates the Adaptive Immune Response by Destabilizing the Immunologic Synapse

Keywords: Inflammatory Bowel Disease; Immune Regulation; Cellular Interactions; Th17; 3-MA; 3-methyladenine; BMDC; bone marrow-derived dendritic cell; DC; dendritic cell; GFP; green fluorescent protein; ICAM-1; intercellular adhesion molecule 1; IL; interleukin;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions

Keywords: Liver Cancer; mRNA Processing; Gene Expression; Cell Death; GFP; green fluorescent protein; HCC; hepatocellular carcinoma; mRNA; messenger RNA; miRNA; microRNA; mTOR; mammalian target of rapamycin; PCR; polymerase chain reaction; PDK1; 3′-phosphoinositi

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Specificity of peripheral nerve regeneration: Interactions at the axon level

Keywords: AKT/PKB; protein kinase B; BDNF; brain derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CAMs; cell adhesion molecules; Cdc42; cell division control protein 42 homolog; cGMP; cyclic guanosine monophosphate; ChAT; choline acetyltransferase

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2012 سفارش ترجمه

mTOR Signaling Pathway and mTOR Inhibitors in Cancer Therapy

Keywords: mTOR; Inhibitor; Rapalog; Cancer;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2012 سفارش ترجمه