NMDA receptor signaling mediates the expression of protein inhibitor of activated STAT1 (PIAS1) in rat hippocampus
Keywords: NMDA; MAPK/ERK; CREB; PIAS1 expression; Hippocampus;
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NMDA receptor blockade impairs the muscarinic conversion of sub-threshold transient depression into long-lasting LTD in the hippocampus-prefrontal cortex pathway in vivo: Correlation with gamma oscillations
Keywords: Muscarinic neurotransmission; NMDA; Hippocampus; Prefrontal cortex; Long-term depression (LTD); Synaptic Plasticity;
Blockade of ventral midbrain NMDA receptors enhances brain stimulation reward: A preferential role for GluN2A subunits
Keywords: Glutamate; GluN2A; GluN2B; NMDA; Reward; Ventral midbrain;
Phencyclidine affects firing activity of ventral tegmental area neurons that are related to reward and social behaviors in rats
Keywords: ANOVA; analysis of variance; AP; action potentials; BNST; bed nucleus of the stria terminalis; CS; conditioned stimuli; ICS; intracranial electrical stimulation; MANOVA; multivariate analysis of variance; mPFC; medial prefrontal cortex; NMDA; N-methyl-d-a
The application of nonlinear Dynamic Causal Modelling for fMRI in subjects at high genetic risk of schizophrenia
Keywords: ACC; Anterior cingulate cortex; BMA; Bayesian Model Averaging; BMS; Bayesian Model Selection; DCM; Dynamic Causal Modelling; EHRS; Edinburgh High Risk Study; IFG; Inferior frontal gyrus; IPS; Intra parietal sulcus; HRÂ +; High risk subjects with psychotic
Involvement of the proteasome and caspase activation in hippocampal long-term depression induced by the serine protease subtilisin
Keywords: aCSF; artificial cerebrospinal fluid; CED; Cambridge Electronic Design; DHPG; dihydroxyphenylglycine; fEPSPs; field excitatory synaptic potentials; HRP; horseradish peroxidase; LTD; long-term depression; LTP; long-term potentiation; MG132; N-[(phenylmetho
N-substituted 8-aminopentacyclo[5.4.0.02,6.03,10.05,9]undecanes as Ï receptor ligands with potential neuroprotective effects
Keywords: CNS; central nervous system; DTG; 1,3-di-o-tolylguanidine; DA; dopamine; DAT; dopamine transporter; HEK; human embryonic kidney; 5-HT; 5-hydroxytryptamine; IP3; inositol-1,4,5-triphosphate; LPS; lipopolysccharide; MAM; mitochondria-associated endoplasmic
In vitro characterisation of the novel positive allosteric modulators of the mGlu5 receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat
Keywords: mGlu5 receptor; Glutamate; NMDA receptor antagonist; Schizophrenia; Psychosis; ADX47273; [S-(4-fluorophenyl)-{3-[3-(4-fluorophenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]; ANCOVA; analysis of covariance; ANOVA; analysis of variance; CDPPB; 3-C
The effects of N-methyl d-aspartate and B-adrenergic receptor antagonists on the reconsolidation of reward memory: A meta-analysis
Keywords: Reconsolidation; Addiction; NMDA; B-Adrenergic; Glutamate; Noradrenaline; Meta-analysis; Reward;
Tau protein kinases: Involvement in Alzheimer's disease
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Arg; Abl-related gene; SFK; Src family kinase; Aβ; β-amyloid; BBB; blood brain barrier; LD50; lethal dose 50; c-Abl; c-Abelson; Cables; c-Abl-binding adaptator protein; CaMKII; Ca2+/calmodulin-dep
Glutamate induces H2O2 synthesis in nonsynaptic brain mitochondria
Keywords: NMDA; N-methyl-D-aspartate; ROS; reactive oxygen species; Mitochondria; Glutamate; Hydrogen peroxide; Succinate dehydrogenase; SDH;
Post-ischemic treatment with L-kynurenine sulfate exacerbates neuronal damage after transient middle cerebral artery occlusion
Keywords: 3-HK; 3-hydroxykynurenine; CNS; central nervous system; dMCA; distal middle cerebral artery; dMCAO; distal middle cerebral artery occlusion; EEG; electroencephalography; I/H; ischemic/hypoxic; KYNA; kynurenic acid; L-KYNs; L-kynurenine sulfate; NDS; norma
Monoamine neurocircuitry in depression and strategies for new treatments
Keywords: 5-HT; 5-hydroxytryptamine, serotonin; BDNF; brain derived neurotrophic factor; CA; catecholamines; Cg25; subgenual cingulate (Brodmann area 25); CNS; central nervous system; CO-MED; Combining Medications to Enhance Depression Outcomes; CRH; corticotropin-
Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells
Keywords: AKT; protein kinase B; L-Arg; l-arginine; L-NAME; N-nitro-l-arginine methyl ester; NO; nitric oxide; NMDA; N-methyl-d-aspartate; MK-801; (5R,2S)-(1)5methyl-10,11-dihydro-5H-dibenzo [a,d] cyclohepten-5,10-imine hydrogen maleate; NOS; nitric-oxide synthase;
Synaptic interactions and inhibitory regulation in auditory cortex
Keywords: Auditory cortex; Glutamate; NMDA; GABA; Thalamocortical; Nicotinic acetylcholine receptor; Mismatch negativity; Synaptic integration; Neuromodulation;
DL-/PO-phosphatidylcholine may shed light on the treatment of Alzheimer dementia
Keywords: Phosphatidylcholine; Donepezil hydrochloride; Alzheimer dementia; MMSE; DL-PC; 1,2-dilinoleoyl-sn-glycero-3-phosphocholine; PO-PC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; MMSE; Mini-Mental State Examination; ACh; acetylcholine; AChEIs; acetylcho
Comparison of the ex vivo receptor occupancy profile of ketamine to several NMDA receptor antagonists in mouse hippocampus
Keywords: Ketamine; GluN2B; NMDA; Autoradiography; Receptor occupancy
Peripheral administration of d-cycloserine rescues memory consolidation following bacterial endotoxin exposure
Keywords: Lipopolysaccharide; Cytokines; d-Cycloserine; BDNF; NMDA; Memory
Effects of blockade of NMDA receptors on cerebral oxygen consumption during hyperosmolar BBB disruption in rats
Keywords: Blood–brain barrier; Cerebral microcirculation; Cerebral blood flow; Cerebral oxygen saturation; Cerebral oxygen consumption; NMDA
Benzodiazepine-like discriminative stimulus effects of toluene vapor
Keywords: Drug discrimination; Inhalant; Toluene; GABA; NMDA
Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test
Keywords: antidepressants; NMDA; AMPA; ligands; forced swim test; mice
Alterations of corticostriatal plasticity by ammonium and rescue by green tea polyphenols
Keywords: Ammonium; Striatum; NMDA; Long-term potentiation; Long-term depression; Green tea polyphenols
Glutamate-Based Antidepressants: Preclinical Psychopharmacology
Keywords: AMPA; depression; GLT-1; mGlu2/3; mGlu5; mGlu7; NMDA; xc-
mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats
Keywords: Animal model; Ethanol; NMDA; Drinking; Rapamycin; Glutamate; Addiction; Rat; Reinforcement; Reward
Basic mechanisms of catastrophic epilepsy – Overview from animal models
Keywords: Infantile spasms; mTOR; Rapamycin; Vigabatrin; Carisbamate; ACTH; Cognitive; ARX; NMDA
NMDA and AMPA receptor mediated excitotoxicity in cerebral cortex of streptozotocin induced diabetic rat: Ameliorating effects of curcumin
Keywords: Diabetes mellitus; NMDA; AMPA; Curcumin; Insulin; Cerebral cortex
Effect of modulating the allosteric sites of N-methyl-D-aspartate receptors in ischemia-reperfusion induced acute kidney injury
Keywords: NMDA; Allosteric modulation; Ischemia-reperfusion; Kidney injury
Differential role of ventral tegmental area acetylcholine and N-methyl-d-aspartate receptors in cocaine-seeking
Keywords: Drug-seeking; NMDA; Acetylcholine; Phasic dopamine; Ventral tegmental area; Nucleus accumbens
Effects of medullary lesions on conditional pacemaker activity of neonatal rat hypoglossal motoneurons in vitro
Keywords: Development; Medulla oblongata; NMDA; Rhythm; Sucking; Tongue; Whole-cell recording; 4V; four ventricle; C preparation; control preparation; CC; central canal; CPG; central pattern generator; DE preparation; dorsally eliminated preparation; DMX; dorsal mo
Ketamine, magnesium and major depression – From pharmacology to pathophysiology and back
Keywords: Major depression; Ketamine; Magnesium; Synaptogenesis; NMDA; NR2b; CP-AMPA; mTOR; CaMKII; P2X7; Aldosterone; Slow wave sleep; Stress
Coordination of NMDA-induced rhythmic activity in the trigeminal and hypoglossal nerves of neonatal mice in vitro
Keywords: Brainstem; Suckling; NMDA; In vitro; Rhythm generation; Mouse;
The role of the neuropeptide S system in addiction: Focus on its interaction with the CRF and hypocretin/orexin neurotransmission
Keywords: NPS; neuropeptide S; NPSR; neuropeptide S receptor; CRF; corticotrophin releasing factor; Hcrt-1/Ox-A; hypocretin-1/orexin-A; GPR154; G protein coupled receptor 154; ppNPS; prepropeptide NPS; Lys-Arg; lysine-arginine; mRNA; messenger RNA; LC; locus co
Neurochemical changes within human early blind occipital cortex
Keywords: ANOVA, analysis of variance; BOLD, blood-oxygen-level-dependent; CSF, cerebral spinal fluid; EB, early blind; FID, free-induction decay; FWHM, full width at half maximum; GM, gray matter; MRS, magnetic resonance spectroscopy; NAA, N-acetyl aspartate; NMDA
Acute atorvastatin treatment exerts antidepressant-like effect in mice via the l-arginine–nitric oxide–cyclic guanosine monophosphate pathway and increases BDNF levels
Keywords: Atorvastatin; Antidepressant-like effect; NMDA; BDNF; Nitric oxide
Losing your inhibition: Linking cortical GABAergic interneurons to schizophrenia
Keywords: Schizophrenia; Interneurons; Cortex; Inhibition; GABA; NMDA; Gamma oscillations; Parvalbumin; Somatostatin; Neuregulin
Actualités dans le traitement étiologique de la sclérose latérale amyotrophique
Keywords: sclérose latérale amyotrophique; neurologie; motoneurone; traitement; survie; amyotrophic lateral sclerosis; neurology; motoneuron; treatment; survival; AALSRS; appel ALS rating scale; ALSFRS; amyotrophic lateral sclerosis functional rating scale; AMM;
Potential roles of zinc in the pathophysiology and treatment of major depressive disorder
Keywords: Zinc; Depression; Major depressive disorder; Neuroprogression; Antidepressants; Glutamate; NMDA; Inflammation; Neuroplasticity; Antioxidant; Forced swim test; GPR39
Dendritic protein synthesis in the normal and diseased brain
Keywords: 4E-BPs; eIF4E binding proteins; ALS; amyotrophic lateral sclerosis; BDNF; brain-derived neurotrophic factor; CaMKII; calcium/calmodulin-dependent kinase II; CPE; cytoplasmic polyadenylation element; CPEB; cytoplasmic polyadenylation element binding protei
Endogenous dynorphins, glutamate and N-methyl-d-aspartate (NMDA) receptors may participate in a stress-mediated Type-I auditory neural exacerbation of tinnitus
Keywords: ACTH; adrenocorticotropic hormone; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; CAP; auditory whole nerve compound action potential; CNS; central nervous system; COX-2; cyclooxygenase-2; ESA; ensemble spectrum of spontaneous neural activi
Endogenous opiates and behavior: 2012
Keywords: Ach; acetylcholine; ACTH; adrenocorticotrophic hormone; ANG; angiotensin; ATP; adenosine triphosphate; BAM22; bovine adrenal medulla 22; BDNF; brain-derived neurotrophic factor; BEND; beta-endorphin; BFNA; beta-funaltrexamine; BNST; bed nucleus of the str
1H-[13C]-Nuclear Magnetic Resonance Spectroscopy Measures of Ketamine's Effect on Amino Acid Neurotransmitter Metabolism
Keywords: GABA; glutamate/glutamine cycle; ketamine; magnetic resonance spectroscopy; medial prefrontal cortex; NMDA
Adult naked mole-rat brain retains the NMDA receptor subunit GluN2D associated with hypoxia tolerance in neonatal mammals
Keywords: Hypoxia; NMDA; Western blot; Naked mole-rat;
Anesthetics and sedatives: Toxic or protective for the developing brain?
Keywords: GABA, γ-aminobutyric acid; HIE, hypoxic-ischemic encephalopathy; NMDA, N-methyl-d-aspartateAnesthesia; Anesthetics; Animal; Brain; Disability; GABA; Learning impairment; Neonate; Neuroapoptosis; Neurodegeneration; Neuroprotection; Neurotoxicity; NMDA; Opi
A novel series of benzimidazole NR2B-selective NMDA receptor antagonists
Keywords: NMDA; NR2B; Glutamate; Ion channel; Depression; Pain; Drug discovery
NMDAR2B tyrosine phosphorylation is involved in thermal nociception
Keywords: CNS; central nervous system; CRF; corticotropin-releasing factor; F; phenylalanine; NMDA; N-methyl-d-aspartate; NTSR; neurotensin receptor; WT; wild-type; Y; tyrosine; GluN2B; Tyrosine phosphorylation; Neurotensin; NTSR2; Hot-plate test; Nociception;
Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test
Keywords: CDPPB; 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamide; NMDA; N-Methyl-d-aspartic acid; Acamprosate; CDPPB; mGlu5 receptor; NMDA; Tail suspension test;
Role of cuneiform nucleus in regulation of sympathetic vasomotor tone in rats
Keywords: Cuneiform nucleus (CnF); Vasomotor tone; Rats; NMDA; AMPA/Kainite receptor; CoCl2;
Involvement of neuronal nitric oxide synthase in cognitive impairment in isoflurane-treated rats
Keywords: POCD; postoperative cognitive dysfunction; nNOS; neuronal nitric oxide synthase; NO; nitric oxide; PSD-95; postsynaptic density protein 95; NMDA; N-methyl-d-aspartate; PBS; phosphate buffered saline; BSA; bovine serum albumin; ABC; avidin-biotin-perox
Extracts from hardwood trees used in commercial paper mills contain biologically active neurochemical disruptors
Keywords: D2; dopamine-2 receptor; GABA(A); gamma aminobutyric acid receptor A; NMDA; N-methyl-d-aspartic acid receptor; mACh-R; muscarinic cholinergic receptor; MAO; monoamine oxidase; GABA-T; GABA-transaminase; AChE; acetylcholinesterase; (GAD); glutamic acid dec
Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders
Keywords: mGluR; Kainate; NMDA; SHANK; Neuroligin; PSD-95; MPEP