
mtDNA mutations in human aging and longevity: Controversies and new perspectives opened by high-throughput technologies
Keywords: GWAS; genome wide association study; OXPHOS; oxidative phosphorylation; ROS; reactive oxygen species; mtDNA; mitochondrial DNA; polγ; polymerase gamma; GEHA; Genetic of Healthy Aging; NGS; next generation sequencing; nDNA; nuclear DNA; 90 +; nonagenaria