دانلود مقالات ISI درباره P-Gp + ترجمه فارسی

Hydrogel-assisted functional reconstitution of human P-glycoprotein (ABCB1) in giant liposomes

Keywords: GUV; giant unilamellar vesicle; Iin,t; fluorescence intensity inside liposome at time, t; Iout,t; fluorescence intensity outside liposome at time, t; kT; rate constant of active transport; NPPB; 5-Nitro-2-(3-phenylpropylamino)benzoic acid; P-gp; P-glycopr

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2015 سفارش ترجمه

Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: Study of 6-substituted pyridine-3-boronic acid derivatives

Keywords: Boronic acids; Pyridine derivatives; Antimicrobial agents; Efflux pump inhibitors; Staphylococcus aureus; a.u.; arbitrary unit; Boc; tert-butoxycarbonyl; n-BuLi; n-butyllithium; EPI; efflux pump inhibitor; EtBr; ethidium bromide; MFS; major facilitator su

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2015 سفارش ترجمه

Synergist bioassays: A simple method for initial metabolic resistance investigation of field Anopheles gambiae s.l. populations

Keywords: P450s; cytochrome P450 oxidases; P-gp; permeable-glycoprotein; PBO; piperonyl butoxide; COE; carboxylesterase; GST; glutathion S-transferase; KD; knock down; KDT; knock down time; MDR; multi drug resistance; Anopheles gambiae; Insecticide resistance; Meta

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of AP-1 and NF-κB in the Up-regulation of P-gp in Vinblastine Resistant Caco-2 Cells

Keywords: P-gp; AP-1; NF-κB; Caco-2 cells; vinblastine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

(E)-Alkenes as replacements of amide bonds: Development of novel and potent acyclic CGRP receptor antagonists

Keywords: CGRP; Migraine; (E)-Alkene; P-gp;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Gene expression of ABC transporters in Cooperia oncophora after field and laboratory selection with macrocyclic lactones

Keywords: Macrocyclic lactones; Doramectin; Ivermectin; P-gp; MRP; Cattle; Resistant nematodes

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Paclitaxel nanosuspension coated with P-gp inhibitory surfactants: II. Ability to reverse the drug-resistance of H460 human lung cancer cells

Keywords: Paclitaxel; Nanosuspension; P-gp; Multi-drug resistance; H460 human lung cancer cells

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Potential modulation on P-glycoprotein and CYP3A by soymilk and miso: In vivo and ex-vivo studies

Keywords: Soymilk powders; Miso; P-gp; CYP3A; Cyclosporine;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Expression of ATP-binding cassette membrane transporters in a HIV-1 transgenic rat model

Keywords: ARVs; antiretroviral drugs; ABC; ATP-binding cassette; BBB; blood-brain barrier; Bcrp/BCRP; breast cancer resistance protein; CNS; central nervous system; GSH; glutathione; GSSG; glutathione disulfide gp120, HIV-1 glycoprotein-120; HIV; human immunodefi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibiton of cytochrome P450 isoenzymes and P-gp activity by multiple extracts of Huang-Lian-Jie-Du decoction

Keywords: Huang-Lian-Jie-Du-Decotion (HLJDD); Cytochrome P450 isoenzymes; P-gp; Herb–drug interactions; Inhibition

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Comparison of MDCK-MDR1 and Caco-2 cell based permeability assays for anti-malarial drug screening and drug investigations

Keywords: MDCK; Madin-Darby canine kidney; MDR1; multi-drug resistance gene 1; Caco-2; colorectal adenocarcinoma; P-gp; P-glycoprotein; Papp; permeability coefficient; PAPMA; parallel artificial membrane permeability assay; LC-MS; liquid chromatography-mass spe

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

P-gp modulating drugs greatly potentiate the in vitro effect of ivermectin against resistant larvae of Haemonchus placei

Keywords: Resistance; Chemical reversal; Macrocyclic lactones; Nematodes; P-gp; Cattle;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A study of Semen Strychni-induced renal injury and herb-herb interaction of Radix Glycyrrhizae extract and/or Rhizoma Ligustici extract on the comparative toxicokinetics of strychnine and brucine in rats

Keywords: AUC; area under concentration-time curve; Cmax; maximum plasma concentration; CYP450; cytochrome P450; P-gp; P-glycoprotein; CMC-Na; sodium carboxymethylcellulose; IS; internal standard; RG; Radix Glycyrrhizae; RL; Rhizoma Ligustici; GL; Radix Glycyrrhi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Le passage transplacentaire des médicaments

Keywords: placenta; médicaments; modèles in vitro; perfusion placentaire; transporteurs; placenta; drugs; in vitro models; placental perfusion; transporters; ABC; adenosine triphosphate-bindingcassette; AGA; α-1 glycoprotéine acide; AMM; autorisation de mise su

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

New oral anticoagulants-what the cardiothoracic surgeon needs to know

Keywords: 16; 37.1; 37.2; AF; atrial fibrillation; ARISTOTLE; Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation; ENGAGE AF-TIMI 48; Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Dipeptide prodrug approach to evade efflux pumps and CYP3A4 metabolism of lopinavir

Keywords: Lopinavir; LPV; Dipeptide prodrug; Uptake; Transport; Permeability; P-gp; MRP2 and metabolism

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Methotrexate-bestatin interaction: Involvement of P-glycoprotein and organic anion transporters in rats

Keywords: MTX; methotrexate; DDI; drug-drug interaction; P-gp; P-glycoprotein; OAT; organic anion transporter; MRP; multidrug resistance-associated protein; BCRP; breast cancer resistance protein; OATP; organic anion transporting polypeptide; KRB; Krebs-Ringer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Trps1 is associated with the multidrug resistance of osteosarcoma by regulating MDR1 gene expression

Keywords: TRPS1; Osteosarcoma; MDR1; P-gp; Chemotherapy; CHIP; Multidrug resistance; TGFbeta-1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Convallatoxin: A new P-glycoprotein substrate

Keywords: NMQ; N-methyl quinidine; DLCs; Digitalis-like compounds; P-gp; P-glycoprotein; HEK293 cells; human embryonic kidney cells; LC-MS; liquid chromatography-mass spectrometry; ABC transporter; ATP-binding cassette transporter; eYFP; enhanced yellow fluores

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy

Keywords: Cerebral amyloid angiopathy; Alzheimer's disease; P-gp; BCRP; ABC transporters; Blood-brain barrier;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Prenatal xenobiotic exposure and intrauterine hypothalamus-pituitary-adrenal axis programming alteration

Keywords: ADME; absorption distribution, metabolism and excretion; AHH; aryl hydrocarbon hydroxylase; CRH; corticotrophin-releasing hormone; CYP; cytochrome P450; DOHaD; developmental origins of health and disease; ECOD; 7-ethoxycoumarin O-deethylase; EROD; 7-ethox

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal

Keywords: ARTs; artemisinin and its derivatives; BCRP; breast cancer resistance protein; DCF-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; DHE; dihydroethidine; 5-FU; 5-fluorouracil; GCLC; glutamate-cysteine ligase catalytic subunit

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Colchicine effect on P-glycoprotein expression and activity: In silico and in vitro studies

Keywords: DMEM; Dulbecco's modified Eagle's medium; EDTA; ethylenediamine tetraacetic acid; FBS; fetal bovine serum; FITC; fluorescein isothiocyanate; GeoMean; geometric mean of fluorescence intensity; Hb; hydrogen bond; IA; inhibited rhodamine 123 accumulation

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Reversal of multidrug resistance in vitro by co-delivery of MDR1 targeting siRNA and doxorubicin using a novel cationic poly(lactide-co-glycolide) nanoformulation

Keywords: Cationic nanoparticles; Doxorubicin; MCF-7/ADR cells; Multidrug resistance; siRNA; P-gp

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Histopathological lesions, P-glycoprotein and PCNA expression in zebrafish (Danio rerio) liver after a single exposure to diethylnitrosamine

Keywords: P-gp; PCNA; Zebrafish; Immunohistochemistry; Hepatocarcinogens

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters

Keywords: MDR reversers; P-gp inhibitors; N,N-bis(alkanol)amine aryl esters; Chemosensitizers; Doxorubicin-resistant erythroleukemia K562 cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP1; multidrug resistance-

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

[11C-carbonyl]CEP-32496: Radiosynthesis, biodistribution and PET study of brain uptake in P-gp/BCRP knockout mice

Keywords: [11C]CEP-32496; PET; BRAF; P-gp; BCRP; [11C]phosgene;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

The ABC gene family in arthropods: Comparative genomics and role in insecticide transport and resistance

Keywords: Traffic ATPases; Primary carriers; Allelochemicals; Multidrug resistance; Detoxification; Phase III; Arthropoda; P-gp; MDR; MRP; BCRP; SUR; Bt toxins;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

A tamoxifen derivative, N,N-diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine, selectively targets P-glycoprotein-positive multidrug resistant Chinese hamster cells

Keywords: DPPE; N,N-Diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine; ABC transporters; ATP-binding cassette transporters; MDR; multidrug-resistance protein; P-gp; P-glycoprotein; CHO; Chinese hamster ovary; ROS; reactive oxygen species; I; inhibitory ribonucleic ac

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2014 سفارش ترجمه

MDR-1 and GST polymorphisms are involved in myelodysplasia progression

Keywords: AML; acute myeloid leukemia; CYP2B6; Cytochrome P450 2B6; del5q; 5qchrosome deletion; Gln; glutamine; GST; glutathione S-transferase; GSTM1; glutathione S-transferase Mu 1; GSTT1; glutathione S-transferase Theta 1; His; histidine; Ile; isoleucine; IPSS; i

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

The association of MDR1 C3435T and G2677T/A polymorphisms with plasma platelet-activating factor levels and coronary artery disease risk in Turkish population

Keywords: CAD; coronary artery disease; PAF; platelet activating factor; MDR1; multidrug-resistance 1; P-gp; P-glycoprotein; PCR; polymerase chain reaction; RFLP; restriction fragment length polymorphism; ELISA; enzyme-linked immunosorbent assay; Coronary artery di

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

An isoquinoline alkaloid from the Chinese herbal plant Corydalis yanhusuo W.T. Wang inhibits P-glycoprotein and multidrug resistance-associate protein 1

Keywords: Corydalis yanhusuo W.T. Wang; Glaucine; Multidrug resistance; ABC transporters; P-gp; MRP1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Potential role of ATP-binding cassette transporters in the intestinal transport of rhein

Keywords: ABC; ATP-binding cassettet; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP2; multidrug resistance-associated protein 2; B; basolateral; A; apical; MDCKII; Mardin-Darby canine kidney II; Rhein; ATP-binding cassette transporters; Rat in

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

BACE1 inhibitors: A head group scan on a series of amides

Keywords: BACE1; Alzheimer's disease; Inhibitors; pKa; P-gp;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Serotonin transporter protein (SERT) and P-glycoprotein (P-gp) binding activity of montanine and coccinine from three species of Haemanthus L. (Amaryllidaceae)

Keywords: AChE; acetylcholinesterase; BBB; blood-brain-barrier; BCRP; breast cancer resistance protein; CNS; central nervous system; P-gp; P-glycoprotein; SERT; serotonin transporter protein; SSRI; selective serotonin reuptake inhibitor; Haemanthus; Amaryllidacea

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Co-treatment with the anti-malarial drugs mefloquine and primaquine highly sensitizes drug-resistant cancer cells by increasing P-gp inhibition

Keywords: VIN; vinblasitne; ATO; atovaquone; CHL; chloroquine; PRL; primaquine; MEF; mefloquine; ART; artesunate; DOY; doxycycline; VER; verapamil; P-gp; p-glycoprotein; DMSO; dimethylsulfoxide; C-PARP; cleaved ploy ADP ribose polymerase; FACS; fluorescence-activat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Doxorubicin decreases paraquat accumulation and toxicity in Caco-2 cells

Keywords: ABCB1; ATP-binding cassette sub-family B member 1; BSA; bovine serum albumin; DMEM; Dulbecco's Modified Eagle's Medium; DOX; doxorubicin; EDTA; ethylenediamine tetraacetic acid; EPQ; ethylparaquat; FBS; fetal bovine serum; GC-IT-MS; gas chromatographyâ€

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Comparative pharmacokinetics of paclitaxel after oral administration of Taxus yunnanensis extract and pure paclitaxel to rats

Keywords: Paclitaxel; Taxus yunnanensis; Pharmacokinetics; Absorption; Bioavailability; P-gp;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Mechanism of inhibition of P-glycoprotein mediated efflux by Pluronic P123/F127 block copolymers: Relationship between copolymer concentration and inhibitory activity

Keywords: Pluronic block copolymer; Multidrug resistance; P-gp; Polymeric micelles; Cellular uptake;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

ReviewClinical management of drug-drug interactions in HCV therapy: Challenges and solutions

Keywords: HCV; hepatitis C virus; DAAs; direct-acting antivirals; HIV; human immunodeficiency virus; SPCs; summary of product characteristics; Peg; polyethylene glycol; BID; twice daily; AKR; aldo-ketoreductases; P-gp; P-glycoprotein; AUC; area under the plasma con

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Application of in vitro biopharmaceutical methods in development of immediate release oral dosage forms intended for paediatric patients

Keywords: BCS; Biopharmaceutics classification system; EMA; European Medicines Agency; FaSSIF; Fasted state simulated intestinal fluid; FDA; (United States) Food and Drug Administration; FeSSIF; Fed state simulated intestinal fluid; GI; Gastrointestinal; IVIVR; In

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Formononetin potentiates epirubicin-induced apoptosis via ROS production in HeLa cells in vitro

Keywords: MDR; multidrug resistance; P-gp; P-glycoprotein; MRPs; MDR-associated proteins; ROS; reactive oxygen species; HeLa; human cervical cancer cells; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; DCF; dichlorofluorescein; EtBr; ethidium b

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Poly(amido amine) dendrimers as absorption enhancers for oral delivery of camptothecin

Keywords: 2D-NOESY NMR; two-dimensional-nuclear overhauser effect nuclear magnetic resonance spectroscopy; BCS; biopharmaceutical classification system; CPT; camptothecin; DI water; deionized water; DLS; dynamic light scattering; DMSO; dimethyl sulfoxide; EDTA; eth

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Reversal of multidrug resistance by the inhibition of ATP-binding cassette pumps employing “Generally Recognized As Safe” (GRAS) nanopharmaceuticals: A review

Keywords: ABC; ATP-binding cassette superfamily; ART; Antiretroviral therapy; AUC; Area-Under-the-Curve; BCS; Biopharmaceutic Classification System; BCRP; Breast cancer resistance protein; CD; Cyclodextrins; CFR; Code of Federal Regulations; CMC; Critical Micellar

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2013 سفارش ترجمه

Interrelationship between ATP-binding cassette transporters and oxysterols

Keywords: ABC; ATP-binding cassette; apo; apolipoprotein; BCRP; breast cancer resistance protein; CYP; cytochrome P450; EC; epoxycholesterol; ER; endoplasmic reticulum; GS-X; glutathione-conjugate; HDL; high-density lipoprotein; INSIG; insulin-inducible genes; 7-KC

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2013 سفارش ترجمه

Enhanced systemic exposure of saquinavir via the concomitant use of curcumin-loaded solid dispersion in rats

Keywords: Saquinavir; Curcumin; Bioavailability; Solid dispersion; P-gp

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of P-glycoprotein and Glutathione S-transferase-pi mediated resistance by fluoxetine in MCF-7/ADM cells

Keywords: Multidrug resistance; Fluoxetine; P-gp; GST-π

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Site dependent intestinal absorption of darunavir and its interaction with ketoconazole

Keywords: Darunavir; P-gp; P450; Ketoconazole; Site dependent absorption; In situ perfusion

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin

Keywords: P-gp; Bestatin; Intestinal absorption; Antiproliferative activityDDI, drug–drug interaction; P-gp, P-glycoprotein; PEPT, H+/peptide transporter; OAT, organic anion transporter; OCT, organic cation transporter; MRP2, multidrug resistance-associated protein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of nifedipine on the pharmacokinetics of repaglinide in rats: Possible role of CYP3A4 and P-glycoprotein inhibition by nifedipine

Keywords: repaglinide; pharmacokinetics; bioavailability; nifedipine; CYP3A4; P-gp; rat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه