دانلود مقالات ISI درباره P-Gp + ترجمه فارسی

Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators

Keywords: MDR; multidrug resistance; ABC; ATP-binding-cassette; P-gp; P-glycoprotein; BCRP; breast cancer-resistance protein; MRP; multidrug-resistance associated protein; Multidrug resistance modulators; P-Glycoprotein;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line

Keywords: MDR; Celecoxib; P-gp; HGF/MET; Autophagy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways

Keywords: Curcuma; Curcumin; P-gp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression

Keywords: MDR, multidrug resistance; P-gp, P-glycoprotein; PXR, Pregnane X Receptor; PBS, phosphate-buffered saline; DMSO, dimethyl sulfoxide.Piperine; P-gp; MDR1; Digoxin transport

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Role of P-glycoprotein in accumulation and cytotoxicity of amrubicin and amrubicinol in MDR1 gene-transfected LLC-PK1 cells and human A549 lung adenocarcinoma cells

Keywords: MDR; multidrug resistance; P-gp; P-glycoprotein; CyA; cyclosporine A; MRP; multidrug-resistance-associated protein; Amrubicin; Amrubicinol; P-glycoprotein; Transporter;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Enhanced Oral Bioavailability of Doxorubicin in a Dendrimer Drug Delivery System

Keywords: PAMAM; doxorubicin; P-gp; oral bioavailability;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Circadian Clock-Controlled Intestinal Expression of the Multidrug-Resistance Gene mdr1a in Mice

Keywords: bZIP; basic leucine zipper; Cry; cryptochrome; DBP; D-site binding protein; E4BP4; E4 promoter binding protein-4; HLF; hepatic leukemia factor; mdr1a; multidrug resistance 1a; PAR; proline- and acid-rich; Per; period; P-gp; P-glyco-protein; TEF; thyrotrop

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI

Keywords: Proteasome inhibitor; Apoptosis; Multidrug resistance; P-gp; MDR-1

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of excipients on breast cancer resistance protein substrate uptake activity

Keywords: Efflux transporter; Inhibitors; BCRP; Excipients; P-gp

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors

Keywords: BACE; AD; Aspartate protease; Macrocycle; P-gp

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

P-Glycoprotein is not present in mitochondrial membranes

Keywords: MDR, multidrug resistance; ABC, ATP-binding cassette; P-gp, P-glycoprotein; HB, homogenization buffer; RB, resuspension buffer; BSA, bovine serum albuminP-glycoprotein; P-gp; Multidrug resistance; Mitochondria; Cellular localization

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Reversal of multidrug resistance of vincristine-resistant gastric adenocarcinoma cells through up-regulation of DARPP-32

Keywords: DARPP-32; Multidrug resistance; Gastric neoplasm; ZNRD1; P-gp;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Expression of cyclooxygenase-2, P-glycoprotein and multi-drug resistance-associated protein in canine transitional cell carcinoma

Keywords: TCC; COX-2; P-gp; MRP; Dog

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Biophysical characterization of MDR breast cancer cell lines reveals the cytoplasm is critical in determining drug sensitivity

Keywords: Dielectrophoresis; P-gp; MDR; Drug sensitivity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Neuronal mdr-1 gene expression after experimental focal hypoxia: A new obstacle for neuroprotection?

Keywords: Hypoxia; Cobalt chloride; MDR-1; P-gp; Multidrug resistance; Astrocytes; Neurons; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model

Keywords: ab; apical to basolateral; AQ; absorptive quotient; AUCT; area under the curve; ba; basolateral to apical; ClR; renal clearance; Cmax; maximum plasma concentration; CYP; cytochrome P450; ER; efflux ratio; F; fraction not metabolised; FA; fraction absorbed

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Jasmonates in cancer therapy

Keywords: Jasmonate; Cancer; Therapy; Drug; Plant; Stress; Mitochondria; ATP; Differentiation; ROS; MAPK; HSP; Bcl-2; p53; P-gp; Drug resistance

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Functional characterization of the brain-to-blood efflux clearance of human amyloid-β peptide (1–40) across the rat blood–brain barrier

Keywords: Alzheimer's disease; Aβ degrading enzyme; Efflux transport; Gender difference; LRP-1; P-gp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Multidrug resistance-related phenotype and apoptosis-related protein expression in ovarian serous carcinomas

Keywords: MDR; P-gp; MRP1; LRP; p53; bcl-2; Bax; Ovarian cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Effects of capsaicin on P-gp function and expression in Caco-2 cells

Keywords: MDR, multidrug resistance; P-gp, P-glycoprotein; PXR, Pregnane X Receptor; PBS, phosphate-buffered saline; DMSO, dimethyl sulfoxideCapsaicin; P-gp; MDR1; Digoxin transport; Caco-2 cells

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

MDR- and CYP3A4-mediated drug–herbal interactions

Keywords: P-gp; CYP3A4; Drug; Herbs; Biovailability; Drug-resistance

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

A topological substructural approach for the prediction of P-glycoprotein substrates

Keywords: TOPS-MODE; P-glycoprotein; P-gp; molecular modeling; in silico; QSAR;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2006 سفارش ترجمه

Pharmacokinetic and pharmacodynamic interactions of morin and cyclosporin

Keywords: CsA; Cyclosporin; Th1; T helper 1; CYP3A4; cytochrome P450 IIIA4; P-gp; P-glycoprotein; Morin; Cyclosporin; Pharmacodynamics; T cells; B cells; Macrophages; Th1/Th2 cytokines;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Evaluation of (R)-[11C]verapamil as PET tracer of P-glycoprotein function in the blood-brain barrier: kinetics and metabolism in the rat

Keywords: [11C]verapamil; P-gp; BBB; Metabolites;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

The anti-leukemic efficacy of the third generation bisphosphonate ONO5920/YM529

Keywords: YM529; ONO5920/YM529; BP; bisphosphonate; P-gp; P-glycoprotein; DNR; daunorubicin; PAM; pamidronate; ZOL; zoledronic acid; Ph+; philadelphia chromosome positive; Ara-C; cytarabine; MDR; multidrug-resistant; FCS; fetal calf serum; CML; chronic myelogeneous

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Validation of the 96 well Caco-2 cell culture model for high throughput permeability assessment of discovery compounds

Keywords: ADME; absorption, distribution, metabolism, elimination; BCS; biopharmaceutics classification system; BMS; Bristol-Myers Squibb Company; HBSS; Hank's balanced salt solution; HEPES; N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid; IAM; immobilized ar

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Phenothiazine maleates stimulate MRP1 transport activity in human erythrocytes

Keywords: MRP1 (ABCC1); multidrug resistance-associated protein 1; MDR; multidrug resistance; BCECF; 2′,7′-bis-(3-carboxyethyl)-5-(and-6)-carboxyfluorescein; P-gp; P-glycoprotein; BCPCF; 2′,7′-bis-(3-carboxypropyl)-5-(and-6)-carboxyfluorescein; PhMs; phenot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Substrate preferences and glucose uptake in glibenclamide-resistant Leishmania parasites

Keywords: Amino acid; Drug resistance; Glibenclamide; Glucose; Glucose uptake; Leishmania; Metabolic substrate; MDR; MRP; P-gp;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

A novel high-throughput automated chip-based nanoelectrospray tandem mass spectrometric method for PAMPA sample analysis

Keywords: ADME; absorption, distribution, metabolism, elimination; DMSO; di-methyl sulphoxide; IAM; immobilized artificial membrane; LC/MS; liquid chromatography/mass spectrometry; HPLC; high pressure liquid chromatography; MDCK; mardin darby canine kidney cells; N

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Increased functional expression of P-glycoprotein in Caco-2 TC7 cells exposed long-term to cadmium

Keywords: Cadmium; Caco-2 TC7; Calcein-AM; Cytotoxicity; P-gp;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Modulation of drug transport by selected flavonoids: Involvement of P-gp and OCT?

Keywords: OCT; organic cation transporter; P-gp; P-glycoprotein; MDR; multidrug resistance; TEA; tetraethylammoniumbromide; MES; 2-(N-morpholino)-ethanesulfonic acid; TEER; transepithelial electrical resistance; DMEM; Dulbecco's modified eagle medium; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay

Keywords: A to B; apical to basolateral; ADME; absorption, distribution, metabolism, elimination; B to A; basolateral to apical; BCRP; breast cancer resistance protein; HBSS; Hank's balanced salt solution; HEPES; N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Multiple drug resistance, antimutagenesis and anticarcinogenesis

Keywords: ABC; ATP-binding cassette; BCRP; breast cancer resistance protein; BDL; bile duct ligation; cMRP; canalicular MRP; cMOAT; canalicular multispecific organic anion transporter; CYP1A1; cytochrome P450 1A1; EGCG; epigallocatechin gallate; gamma-GT; gamma-glu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Differential sensitization of cancer cells to doxorubicin by DHA: A role for lipoperoxidation

Keywords: DHA; docosahexaenoic acid; DMSO; dimethyl sulfoxide; EPA; eicosapentaenoic acid; GSH; glutathione (reduced); GSSG; glutathione (oxidized); MDR; multidrug resistance; PBS; phosphate-buffered saline; P-gp; P-glycoprotein; PUFA; polyunsaturated fatty acid; R

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (β-d-glucuronate)

Keywords: ABC transporter; ATP-binding cassette transporter; ACNU; 3-[(4-amino-2-methyl-5-pyrimidinyl) methyl]-1-(2-chloroethyl)-1-nitrosourea; ADM; adriamycin; AG-A; agosterol A; azidoAG-A; [125I] 11-azidophenyl agosterol A; AZT; azidothymidine; BSO; buthionine su

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR)

Keywords: AR; androgen receptor; β-Gal; β-galactosidase; CYP3A; cytochrome P4503A; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; DR3; direct repeat with 3 nucleotide spacer; EC50; effective concentration for half-maximal response; ER; estrogen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Bacterial efflux systems and efflux pumps inhibitors

Keywords: Bacterial resistance; Efflux systems; Efflux pump inhibitors; ABC; ATP-binding cassette; EPI; efflux pump inhibitor; MATE; multi-drug and toxic compound extrusion; MDR; multi-drug resistance; MFS; major facilitator superfamily; MRSA; methicillin-resistant

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Bidirectional transfer of methadone across human placenta

Keywords: PK; pharmacokinetics; P-gp; P glycoprotein; NAS; neonatal abstinence syndrome; BUP; bupremorphine; LAAM; l-α-acetylmethadol; AP; antipyrine; M → F; maternal to fetal; F → M; fetal to maternal; EDDP; 2-ethyliolene-1,5-dimethyl-3,3-diphenylpyrrolid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Transport of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide by human intestinal Caco-2 cells

Keywords: ACSRC; Auckland Cancer Society Research Centre; AP; apical; BL; basolateral; CYP; cytochrome P450; DMSO; dimethyl sulphoxide; DMXAA; 5,6-dimethylxanthenone-4-acetic acid; DMXAA-G; DMXAA acyl glucuronide; HBSS; Hanks' balanced salt solution; HEPES; N-[2-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Nucleotide dissociation from NBD1 promotes solute transport by MRP1

Keywords: P-gp; P-glycoprotein; MRP1; multidrug resistance-associated protein 1; NBD; nucleotide binding domain; LTC4; leukotriene C4; SDS; sodium dodecyl sulfate; EDTA; ethylenediaminetetraacetic acid; 8-N3ATP; 8-azidoadenosine 5′-triphosphate; Sf21; Spodoptera

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه