دانلود مقالات ISI درباره Pdb + ترجمه فارسی

Appraisal of sildenafil binding on the structure and promiscuous esterase activity of native and histidine-modified forms of carbonic anhydrase II

Keywords: hCA; human carbonic anhydrase; PDE5; phosphodiesterase-5; CD; circular dichroism; PSH; protein surface hydrophobicity; ANS; 1,8-anilinonaphtalene sulfonate; PDB; protein data bank; ED; erectile dysfunction; CAIs; CA inhibitors; DEPC; diethyl pyrocarbonate

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Structure and function of atypically coordinated enzymatic mononuclear non-heme-Fe(II) centers

Keywords: 1,3-bis(2-pyridylimino)isoindoline; ind; 2OH-1,3-Ph2PD; 2-hydroxy-1,3-diphenylpropanedione; 6-Ph2TPA; N,N-bis[(6-phenyl-2-pyridyl)methyl]-N-[(2-pyridyl)-methyl]amine; α-KG; α-ketoglutarate; acac; acetylacetone (2,4-pentanedione); ADO; cysteamine dioxyge

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2013 سفارش ترجمه

Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling

Keywords: RA; rheumatoid arthritis; FLS; fibroblast-like synoviocytes; ACPA; anti-citrullinated peptide antibody; DKK1; dickkopf-1; 11β-HSD1; 11beta-hydroxysteroid dehydrogenase type 1; PADI4; peptidylarginine deiminase-4; hTERT; human telomerase reverse transcrip

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of irrigation on the relationships between leaf gas exchange related traits and yield in dwarf dry bean grown under Mediterranean conditions

Keywords: A; net assimilation rate; A/E; instantaneous water use efficiency; A/gs; intrinsic water use efficiency; ANOVA; analysis of variance; Ci; intercellular CO2 concentration; E; transpiration rate; Eo; pan evaporation; ET; evapotraspiration; Δ; carbon isotop

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Structural analysis of cytochrome bc1 complexes: Implications to the mechanism of function

Keywords: bc1; complex III or ubiquinol cytochrome c oxidoreductase or cytochrome bc1; bL; low-potential heme or b566; bH; high-potential heme or b562; Btbc1; Bos taurus bc1; CA; contact area; CL; cardiolipin; ET; electron transfer; Ggbc1; Gallus gallus bc1; ISC; i

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Unanswered questions about the structure of cytochrome bc1 complexes

Keywords: QP, QN; quinone processing active sites of the bc complex near the negative (-) and positive (QP) surfaces of the energy transducing membrane; cyt; cytochrome; ISP; iron-sulfur protein; nHDBT; alkylhydroxydioxobenzothiazole; MPP; matrix processing pep

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2013 سفارش ترجمه

Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors

Keywords: Amide bioisostere; HCV; Thumb; PDB; Hydrazine;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

An analysis of B-cell epitope discontinuity

Keywords: ASA; accessible surface area; PDB; Protein Data Bank; Antigen; Antibody; Epitope; Structural epitope; Functional epitope;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-β-lactamase active sites

Keywords: MBL; metallo-β-lactamase; AP; alkaline phosphatase; VAP; Vibrio alkaline phosphatase; ECAP; E. coli alkaline phosphatase; SAP; shrimp alkaline phosphatase; PDB; Protein Data Bank; CLASP; CataLytic Active Site Prediction; pNPP; p-nitrophenyl phosphate dis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima

Keywords: 7-ACA; 7-aminocephalosporanic acid; BTB; bromothymol blue; CE7; carbohydrate esterase family 7; DSF; differential scanning fluorimetry; LB; Luria-Bertani broth; MWCO; molecular weight cut-off; Ni-NTA; nickel-nitrilotriacetic acid; NPA; 4-nitrophenol ace

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers

Keywords: Fab; Antigen-binding fragment; PDB; Protein Data Bank; AD; Alzheimer's disease; M204; Monoclonal antibody 204; PFOs; Prefibrillar oligomers; Aβ; Amyloid beta peptide; FOs; Fibrillar oligomers; APFs; Annular protofibrils; IgG; Immunoglobulin G; (HEK293) c

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability

Keywords: RMSD; root mean square deviation; PDB; Protein Data Bank; Trx; thioredoxin; TrxR; thioredoxin reductase; SsTrxA2; Sulfolobus solfataricus Trx A2; SsTrxA1; Sulfolobus solfataricus Trx A1; EcTrx; Escherichia coli Trx; TtTrx; Thermus thermophilus Trx; SpTrx;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

In silico identification of catalytic residues and domain fold of the family GH119 sharing the catalytic machinery with the α-amylase family GH57

Keywords: CAZy; Carbohydrate-Active enZyme; CSR; conserved sequence region; GH; glycoside hydrolase; PDB; Protein Data Bank; α-Amylase; Family GH119; Family GH57; Catalytic machinery; Conserved sequence region; Evolutionary relatedness;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of a mutation in LARS as a novel cause of infantile hepatopathy

Keywords: SNP; single nucleotide polymorphism; PDB; protein data-bank; siRNA; small-interfering ribonucleic acid; LARS; gene encoding the cytoplasmic leucyl-tRNA synthetase; MMP; mitochondrial membrane potential; ROS; reactive oxygen species; LeuRS; leucyl-tRNA syn

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs

Keywords: ACHBP; acetylcholine-binding protein; DMXBA; 3-(2,4-dimethoxybenzilidene)-anabaseine; HBD; hydrogen-bond donor; nAChR; nicotinic acetylcholine receptor; Pdb; protein databank; rmsd; root-mean-squared-deviation; ROC; receiver operating characteristic curve

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of an active dimeric intermediate populated during the unfolding process of the cambialistic superoxide dismutase from Streptococcus mutans

Keywords: Superoxide dismutase; Thermal stability; Chemical stability; Dimeric intermediate; Unfolding; ANS; 1-anilino-8-naphthalene sulfonate; BsSOD; superoxide dismutase (SOD) from Bacillus subtilis; C1/2; concentration of denaturant at midpoint denaturation; EcS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Computational methods for prediction of protein-RNA interactions

Keywords: AUC; area under receiver operating characteristic curve; cryo-EM; cryo-electron microscopy; DARS-RNP; decoys as reference state based potential to assess structure of protein-RNA complexes; FPR; false positive rate (1 - specificity); HMM; Hidden Marko

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Design, synthesis and in vitro evaluation of a series of α-substituted phenylpropanoic acid PPARγ agonists to further investigate the stereochemistry-activity relationship

Keywords: NR; nuclear receptor; hPPAR; human peroxisome proliferator-activated receptor; RXR; retinoid X receptor; LBD; ligand-binding domain; PDB; protein data bank; Peroxisome proliferator-activated receptor; PPAR; PPARγ; Phenylpropanoic acid; SAR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Enriching the human apoptosis pathway by predicting the structures of protein-protein complexes

Keywords: AIF; apoptosis-inducing factor, mitochondrion-associated, 1; Apaf-1; apoptotic peptidase activating factor 1; Bax; BCL2-associated X protein; Bcl-2; B-cell lymphoma 2; Bcl-XL; Bcl-extra large; Bid; BH3 interacting domain death agonist; CASP3; caspase-3; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly

Keywords: AAA; ATPase associated with diverse cellular activities; AU; analytical ultracentrifugation; EM; electron microscopy; NSF; N-Ethylmaleimide Sensitive Factor; PDB; Protein Data Base; SNAP; Soluble NSF Attachment Protein; SNARE; SNAP Receptor; VCP; Valosin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Surface masking shapes the traffic of the neuropeptide Y Y2 receptor

Keywords: AcLeu; human neuropeptide Y(24-36) acetyl-Leu(28 31); BIBP326; R-N 2-(diphenylacetyl)-N-(4-hydroxyphenyl)methyl-arginineamide; BIIE0246; N-[(1S)-4-[(aminoiminomethyl)amino]-1-[([2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino)carbonyl]butyl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The only exoribonuclease present in Haloferax volcanii has an unique response to temperature changes

Keywords: RNase; ribonuclease; CSD; Cold Shock Domain; DTT; Dithiothreitol; EDTA; Ethylenediaminetetraacetic acid; SPR; Surface plasmon resonance; PDB; protein data bank; PNPase; Polynucleotide phosphorylase; PAP I; Poly(A) Polymerase; RMSD; Root mean square deviat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic and biochemical characterization of Corynebacterium glutamicum ATP phosphoribosyltransferase and its three mutants resistant to feedback inhibition by histidine

Keywords: ATP phosphoribosyltransferase; Corynebacterium glutamicum; Feedback inhibition; Histidine; Mutagenesis; HisGCg; ATP phosphoribosyltransferase from Corynebacterium glutamicum; ATP-PRT; ATP phosphoribosyltransferase; CD; circular dichroism; DTT; dithiothrei

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Benzimidazole inhibitors of the protein kinase CHK2: Clarification of the binding mode by flexible side chain docking and protein-ligand crystallography

Keywords: ADP; adenosine diphosphate; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; CHK2; checkpoint kinase 2; GOLD; genetic optimisation for ligand docking; GST; glutathione S-transferase; KD; kinase domain; MOE; molecular operating environment;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

MH2c: Characterization of major histocompatibility α-helices - an information criterion approach

Keywords: MH2c; MH helix curves (name of software); TR; T cell receptor; p; peptide; MH; major histocompatibility; MH1; major histocompatibility class I; MH2; major histocompatibility class II; G; binding groove; CDR; complementarity determining region; MD; Molecul

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

A β-galactosidase from chick pea (Cicer arietinum) seeds: Its purification, biochemical properties and industrial applications

Keywords: CpGAL; chick pea β-galactosidase; ONPG; o-nitrophenyl-β-d galactopyranoside; PNPG; p-nitrophenyl-β-d galactopyranoside; X-Gal; 5-bromo-4-chloro-3-indolyl-β-d-galactopyranoside; PMSF; phenylmethanesulfonyl fluoride; DTT; dithiothreitol; DMF; N,N-dimeth

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and evaluation of malonate-based inhibitors of phosphosugar-metabolizing enzymes: Class II fructose-1,6-bis-phosphate aldolases, type I phosphomannose isomerase, and phosphoglucose isomerase

Keywords: 5PAH; 5-phospho-d-arabinonohydroxamic acid; F6P; d-fructose 6-phosphate; FBA; fructose-1,6-bis-phosphate aldolase; FBP; d-fructose 1,6-bis-phosphate; G6P; d-glucose 6-phosphate; HEI; high energy intermediate; M6P; d-mannose-6-phosphate; β-M6P; β-d-manno

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation

Keywords: Ab; antibody; GK; glucokinase; GKRP; glucokinase regulatory protein; Glc; α-d-glucose; HEK293; human embryonic kidney 293 cells; hGK; human glucokinase; MIN6; mouse insulinoma cell; MODY; maturity-onset diabetes of the young; PDB; protein data bank; PNS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Crystal structure of 1,3Gal43A, an exo-β-1,3-galactanase from Clostridium thermocellum

Keywords: Ct1,3Gal43A; Clostridium thermocellum exo-β-13-galactanase; r.m.s.d.; root mean square deviation; PDB; Protein Databank; GH43; glycoside hydrolase family 43; CBM; carbohydrate binding module; CAZy; Carbohydrate-Active EnZymes database; Ct1,3Gal43A; GH43;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Modeling ADAMTS13-von Willebrand Factor interaction: Implications for oxidative stress-related cardiovascular diseases and type 2A von Willebrand Disease

Keywords: ADAMTS; A Disintegrin-like And Metalloprotease with ThromboSpondin type I repeats; a.m.u; atomic mass units; CaBS; calcium binding site; M13; the metalloprotease domain of ADAMTS-13; MetSO; methionine sulfoxide; PDB; Protein Data Bank; PN; peroxynitrite;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties

Keywords: AMPCPP; α,β-methyleneadenosine 5′-triphosphate; HP; 6-hydroxymethyl-7,8-dihydropterin; HP-1; 6-hydroxymethyl-7,7-dimethyl-7,8-dihydropterin; HP-3; 6-hydroxymethyl-7-methyl-7-phenethyl-7,8-dihydropterin; HP2A; P1-(6-hydroxymethylpterin)-P2-(5′-adenos

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents

Keywords: Anticancer; Naphthalene diimides; Multitarget-directed ligands; Cytotoxicity; BrdU; bromodeoxyuridine; CD; circular dicroism; dsDNA; double strand DNA; DTP; Developmental Therapeutics Program; EtBr; Ethidium bromide; ERK; extracellular signal regulated ki

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of the critical structural determinants of the EF-hand domain arrangements in calcium binding proteins

Keywords: Ca2+; calcium; CaBPs; calcium binding proteins; CaM; calmodulin; CNB; calcineurin B; SCP; sarcoplasmic calcium binding protein; TnC; troponin C; TnI; troponin I; TnT; troponin T; Tn; troponin; hCLP; human calmodulin-like protein; CIB1; calcium and integri

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Rotational velocity rescaling of molecular dynamics trajectories for direct prediction of protein NMR relaxation

Keywords: RVR; rotational velocity rescaling; GB3; B3 domain of Protein G; PDB; protein data bank; MD; molecular dynamics; rms; root mean square; RDC; residual dipolar coupling; NOE; nuclear Overhauser enhancement; CSA; chemical shift anisotropy; ROESY; rotating fr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Comparative modeling of HGPRT enzyme of L. donovani and binding affinities of different analogs of GMP

Keywords: HGPRT; hypoxanthine-guanine phosphoribosyl transferase; HPRT; hypoxanthine phosphoribosyltransferase; CL; cutaneous leishmaniasis; MCL; muco-cutaneous leishmaniasis; VL; visceral leishmaniasis; PKDL; post-kala-azar dermal leishmaniasis; BLAST; basic local

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular analysis of Plasmodium falciparum co-chaperone Aha1 supports its interaction with and regulation of Hsp90 in the malaria parasite

Keywords: 5-FOA; 5-fluoroorotic acid; ADP; adenosine diphosphate; Aha1; Activator of Hsp90 ATPase 1; ATP; adenosine triphosphate; Cub; C-terminal half of ubiquitin; DNA; deoxyribonucleic acid; GST; glutathione S-transferase; His6; hexa-histidine; Hsp90; Heat shock

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Experimentally assessing molecular dynamics sampling of the protein native state conformational distribution

Keywords: BPTI; bovine pancreatic trypsin inhibitor; PDB; protein data bank; RDC; residual dipolar coupling; NOE; nuclear Overhauser enhancement; MD; molecular dynamics; PB; Poisson-Boltzmann; Protein ensemble; Hydrogen exchange; Continuum electrostatics; Protein

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape

Keywords: CAN gene; candidate cancer gene; CD; cluster of differentiation; CDK; cyclin-dependent kinase; COPA; cancer outlier profile analysis; DNMT; DNA methyltransferase; GRN; gene regulatory network; HDAC; histone deacetylase; H3K9; Histone H3 lysine 9; ICBP90;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Alternaria alternata allergen Alt a 1: A unique β-barrel protein dimer found exclusively in fungi

Keywords: Asthma; allergens; molds; Alt a 1; Alternaria species; x-ray crystallography; protein structure; oligomeric structure; 4-HTP; 4-Hydroxy-2,5,6-triaminopyrimidine; 8-ACA; 8-Aminocaprylic acid; DLS; Dynamic light scattering; gi; GenInfo Identifier; PDB; Prot

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors

Keywords: ATP; adenosine triphosphate; Boc; tert-butoxycarbonyl; CDI; 1,1′-carbonyldiimidazole; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; DNPH; O-(2,4-dinitrophenyl)hydroxylamine; EDTA; ethylenediaminetetraacetic acid; ip; intraperitoneal; MEM; minimu

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

MSTools-Web based application for visualization and presentation of HXMS data

Keywords: AA; amino acid; PDB; protein data bank; HXMS; hydrogen exchange-mass spectrometry; H/D; hydrogen/deuterium; Hydrogen/deuterium exchange; Data visualization; Software; Web application;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Water transport in human aquaporin-4: Molecular dynamics (MD) simulations

Keywords: MD; molecular dynamics; SMD; steered MD; PDB; protein data bank; RMSD; root mean-squared deviation; POPC; palmitoyl-oleoyl-phosphatidyl-choline; PSF; protein structure file; NPA; Asn-Pro-Ala; PME; Particle Mesh Ewald; BD-FDT; brownian dynamics fluctuation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

X-ray structure of a galactose-specific lectin from Spatholobous parviflorous

Keywords: SPL; Spatholobous parviflorus lectin; CM; carboxy methyl; PEG; poly ethylene glycol; MPD; 2-methyl-2,4-pentane diol; MALDI-ToF; matrix assisted laser desorption/ionization time-of-flight; PDB; Protein Data Bank; Spatholobous parviflorus; Jelly roll; Legum

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

A tool for the qualitative comparison of membrane-embedded and detergent-solubilized membrane protein structures in projection

Keywords: Electron crystallography; Membrane protein; Projection structure; Transmission electron microscopy; Transporter; Two-dimensional crystal; X-ray crystallography; gBF; global B-factor; EC; electron crystallography; PDB; Protein Data Bank; PS; projection str

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

How vaccinia virus has evolved to subvert the host immune response

Keywords: Bcl-2; B-cell lymphoma-2; CPXV; Cowpox virus; dsDNA; double-stranded DNA; ECTV; ectromelia virus; GAGs; glycosaminoglycans; GPCRs; G-protein coupled receptors; IFN; interferon; IG; immunoglobulin; PDB; protein data bank; RPXV; rabbitpox virus; r.m.s.d.; r

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Analogs of 5-(substituted benzylidene)hydantoin as inhibitors of tyrosinase and melanin formation

Keywords: AcOH; Acetic acid; ANOVA; Analysis of variance; CaH2; Calcium hydride; CO2; Carbon dioxide; CDCl3; Deuterated chloroform; l-DOPA; l-3,4-dihydroxyphenylalanine; DMSO; Dimethyl sulfoxide; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DM

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Crystal structures of Trichoderma reesei β-galactosidase reveal conformational changes in the active site

Keywords: Glycosyl hydrolase; β-Galactosidase; Crystal structure; Conformational changes; Octaserine; Tr-βgal; Trichoderma reesei β-galactosidase; Psp-β-gal; Penicillium sp. β-galactosidase; Btm-β-gal; Bacteroides thetaiotaomicron VPI-5482 β-galactosidase; I

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Determination of thermal intermediate state ensemble of box 5 with restrained molecular dynamics simulations

Keywords: HUBF; Human upstream binding factor; HMG; High mobility group; IS; Intermediate state; MD; Molecular dynamics; NMR; Nuclear magnetic resonance; NOE; Nuclear Overhauser Enhancement; PRE; Paramagnetic relaxation enhancement; RMSDCα; Root mean square deviat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Three-state thermal unfolding of onconase

Keywords: CD; circular dichroism; NMR; nuclear magnetic resonance; DSC; differential scanning calorimetry; ANS; 8-anilino-1-naphtalenesulfonate; RCSB; Research Collaboratory for Protein Bioinformatics; PDB; Protein Data Bank; ESRF; European Synchrotron Radiation Fa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Non-specific binding and general cross-reactivity of Y receptor agonists are correlated and should importantly depend on their acidic sectors

Keywords: BIBP3226; (R)-N2-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]d-arginineamide; BIIE0246; N-[(1S)-4-[(aminoiminomethyl)amino]-1-[([2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino)carbonyl]butyl]-1-(2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه