دانلود مقالات ISI درباره دامنه PDZ + ترجمه فارسی

گیرنده های پروستات سیکلین: تنظیمات ترانسکتیکی و مکانیسم های جدید سیگنالینگ

Prostacyclin receptors: Transcriptional regulation and novel signalling mechanisms

Keywords: دامنه PDZ; Prostacyclin receptor; Estrogen receptor; Sterol response element binding protein (SREBP); PDZK1(PDZ-domain-containing protein 1); IKEPP (intestinal and kidney enriched PDZ protein); C/EBP, CCAAT/enhancer binding protein; Rab11; Gene; Cardiovascular; AoSM

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

درمان با لیپید غشاء: مدولاسیون ترکیب و ساختار غشای سلولی به عنوان پایه مولکولی برای کشف دارو و درمان بیماری های جدید

Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment

Keywords: دامنه PDZ; AA; arachidonic acid; Aβ; fibrillar β-amyloid; ACC; acetyl-CoA carboxylase; Akt; protein kinase B; APP; amyloid precursor protein; ASAH2; neutral ceramidase; BA; benzyl alcohol; BBB; blood-brain-barrier; BMI; body mass index; BPM; bis(monoacylglycero)

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

تعامل NOS1AP با دامنه NOS-I PDZ: پیامدها برای تغییرات وابسته به اسکیزوفرنی در مورفولوژی دندریتیک

Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology

Keywords: دامنه PDZ; NOS1AP; Nos1; PDZ domain; Dendrite development; Spine plasticity; Mouse;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

HtrA3 is a cellular partner of cytoskeleton proteins and TCP1α chaperonin

Keywords: دامنه PDZ; CS; citrate synthase; ELISA; enzyme-linked immunosorbent assay; HtrA; High-temperature requirement A; MAPs; microtubule associated proteins; MST; MicroScale Thermophoresis; MT; microtubule; PD; protease domain; PDZ domain; postsynaptic density protein 95

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Efficient synthesis of CN2097 using in situ activation of sulfhydryl group

Keywords: دامنه PDZ; CN2097; Disulfide; Fmoc/tBu; Polyarginine; PDZ domain; Solid-phase chemistry;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Optimization of the process of inverted peptides (PIPEPLUS) to screen PDZ domain ligands

Keywords: دامنه PDZ; SPOT synthesis; C-terminus; PDZ domain; Peptide array; Cellulose functionalization;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

The role of the LB structural loop and its interactions with the PDZ domain of the human HtrA3 protease

Keywords: دامنه PDZ; HtrA; high temperature requirement A; PD; protease domain; PDZ domain; Postsynaptic density protein 95, Drosophila disc large tumor suppressor and Zonula occludens-1 protein domain; XIAP; X-linked Inhibitor of Apoptosis Protein; HtrA proteins; Human HtrA3

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Structural insights into the activation mechanisms of human HtrA serine proteases

Keywords: دامنه PDZ; HtrA proteins; Serine proteases; Allosteric regulation; PDZ domain;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5

Keywords: دامنه PDZ; Dvl-1; PDZ domain; CXXC5; Wnt signaling; X-ray crystallography;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex

Keywords: دامنه PDZ; Arg1; Arginase 1; DH-PH domain; the diffuse B-cell lymphoma (Dbl) domain and pleckstrin-homology domain; GDP; guanosine diphosphate; GEF; guanine exchange factor; GM130; 130 kDa cis Golgi matrix protein; GTP; guanosine triphosphate; INF-γ; Interferonγ;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-Bas

Keywords: دامنه PDZ; Protein tyrosine phosphatase-Basophil; PDZ domain; Tandem-PH-domain-containing protein-1; Crystal structure; Binding specificity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies

Keywords: دامنه PDZ; Dishevelled; PDZ domain; Pharmacophore; Wnt; Virtual screening; Docking; Surface plasmon resonance; Fluorescence spectroscopy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Binding of PDZ domains to the carboxy terminus of inducible nitric oxide synthase boosts electron transfer and NO synthesis

Keywords: دامنه PDZ; iNOS; Reductase; Electron transfer; PDZ domain;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus

Keywords: دامنه PDZ; PDZ domain; Rabies virus; Neurons; Neuronal signaling; Phosphorylation; Enzymatic regulation; CytoG; C-terminal cytoplasmic tail of G protein; MAST2; microtubule-associated serine and threonine kinase 2; PBM; PDZ binding motif; PDZ; PSD-95/Dlg/ZO-1; PSD;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

SAP97 blocks the RXR ER retention signal of NMDA receptor subunit GluN1-3 through its SH3 domain

Keywords: دامنه PDZ; ER; endoplasmic reticulum; IC; intermediate compartment; SAP97; NMDA; Receptor; Trafficking; PDZ domain; SH3 domain; RXR motif;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The role of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in depression: Central mediators of pathophysiology and antidepressant activity?

Keywords: دامنه PDZ; AMPA receptors; Ampakines; Ketamine; Psychiatric disorders; Depression; MDD; Glutamatergic synapse; PDZ domain; Synaptic plasticity; Neuroplasticity;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Structure-function analysis of SAP97, a modular scaffolding protein that drives dendrite growth

Keywords: دامنه PDZ; PDZ domain; GluA1; Spinal cord neuron;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Using a collection of MUPP1 domains to investigate the similarities of neurotransmitter transporters C-terminal PDZ motifs

Keywords: دامنه PDZ; Neurotransmitter transporters; PDZ motif; PDZ domain; MUPP1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

A thermodynamic study of the third PDZ domain of MAGUK neuronal protein PSD-95 reveals a complex three-state folding behavior

Keywords: دامنه PDZ; PDZ domain; Oligomeric intermediate; Differential scanning calorimetry; Three-state model; Thermodynamics; Protein folding;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis

Keywords: دامنه PDZ; Urogenital system; PDZ domain; Hydronephrosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PDZ affinity chromatography: A general method for affinity purification of proteins based on PDZ domains and their ligands

Keywords: دامنه PDZ; HaloTag; PDZ domain; Affinity chromatography; NMDA receptor; synGAP; Neuronal;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Ligand binding of PDZ domains has various roles in the synaptic clustering of SAP102 and PSD-95

Keywords: دامنه PDZ; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionate; DIV; day in vitro; EGFP; enhanced green fluorescent protein; MAGUK; membrane-associated guanylate kinase; PBS; phosphate-buffered saline; PDZ; PSD-95/discs large/zona occludens-1; PSD; postsynaptic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Modulatory roles of NHERF1 and NHERF2 in cell surface expression of the glutamate transporter GLAST

Keywords: دامنه PDZ; PDZ; PSD-95/Drosophila discs-large protein/zonula occludens protein; NHERF; Na+/H+ exchanger regulatory factor; ER; endoplasmic reticulum; ERGIC; ER-Golgi intermediated compartment; EGFP; enhanced green fluorescent protein; COPII; coatomer protein compl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Biochemical and structural insights into intramembrane metalloprotease mechanisms

Keywords: دامنه PDZ; S2P; site-2 protease; PDZ; (PSD-95, DLG, ZO-1); CBS; (cystathionine-β-synthase); IP(s); intramembrane protease(s); SREBP(s); sterol-regulatory element-binding protein(s); TMS(s); transmembrane segment(s); IMMP(s); intramembrane metalloprotease(s); RNAP;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Homer proteins accelerate Ca2+ clearance mediated by the plasma membrane Ca2+ pump in hippocampal neurons

Keywords: دامنه PDZ; Homer; PMCA; PDZ domain; Ca2+ signaling; Hippocampal neuron

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

NMR evaluation of interactions between substituted-indole and PDZ1 domain of PSD-95

Keywords: دامنه PDZ; PDZ domain; Protein–protein interaction; PSD-95; Analgesia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Irving Page Lecture: 5-HT2A serotonin receptor biology: Interacting proteins, kinases and paradoxical regulation

Keywords: دامنه PDZ; PDZ domain; Functional selectivity; Antipsychotic; Psychoactive; RSK2; Caveolin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Solution structure of HtrA PDZ domain from Streptococcus pneumoniae and its interaction with YYF–COOH containing peptides

Keywords: دامنه PDZ; Streptococcus pneumoniae; HtrA; PDZ domain; NMR; Peptide-binding module

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and evaluation of bidentate ligands designed to interact with PDZ domains

Keywords: دامنه PDZ; CDI; carbonyldiimidazole; Cyc; cyclohexane; DABCO; diazabicyclooctane; DCM; dichloromethane; DIEA; diisopropylethylamine; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; EDC; 1-ethyl-3-(3-dimethylamino propyl)carbodiimide; EtOAc; ethylacetate;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The structural basis of mode of activation and functional diversity: A case study with HtrA family of serine proteases

Keywords: دامنه PDZ; HtrA; PDZ domain; Active site; Protease; Chaperone

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis, structure and binding properties of PDZ binding, cyclic β-finger peptides

Keywords: دامنه PDZ; NMR; Peptide structure; Cyclic peptides; PDZ domain; Ligand binding; ITC; Peptide synthesis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

dGIPC is required for the locomotive activity and longevity in Drosophila

Keywords: دامنه PDZ; DA, dopaminergic; GAIP, Gα interacting protein; TH, tyrosine hydroxylase; GIPC, GAIP interacting protein, C terminus; GPCR, G-protein coupled receptorP element mutagenesis; Central nervous system; Lifespan; Glia; PDZ domain; Drosophila

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Sphingosine-1-phosphate receptor S1P1 is regulated by direct interactions with P-Rex1, a Rac guanine nucleotide exchange factor

Keywords: دامنه PDZ; Sphingosine-1-phosphate; S1P1; P-Rex1; Cell migration; PDZ domain

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Differential roles of GRIP1a and GRIP1b in AMPA receptor trafficking

Keywords: دامنه PDZ; Synaptic plasticity; LTD; Palmitoylation; Glutamate; PDZ domain;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Hypoxia induces the PDZ domain-containing syntenin in the marine teleost Paralichthys olivaceus

Keywords: دامنه PDZ; Syntenin; PDZ domain; Hypoxia; Olive flounder; Paralichthys olivaceus

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Chlamydial protease CT441 interacts with SRAP1 co-activator of estrogen receptor α and partially alleviates its co-activation activity

Keywords: دامنه PDZ; Chlamydiaceae; Estrogen receptor α; Steroid receptor RNA activator 1; PDZ domain; CT441 protease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Reversible hydrogel formation driven by protein–peptide–specific interaction and chondrocyte entrapment

Keywords: دامنه PDZ; Chondrocyte; CutA; Hydrogel; Interaction; TIP1; PDZ domain

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization

Keywords: دامنه PDZ; PICK1; PDZ domain; Phosphorylation; AMPA receptor; Protein trafficking;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Different domains of C. elegans PAR-3 are required at different times in development

Keywords: دامنه PDZ; Cell polarity; PAR-3; Phosphorylation; PDZ domain

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

A novel nitric oxide synthase expressed specifically in the olfactory center

Keywords: دامنه PDZ; Nitric oxide synthase; Procerebrum; Local field potential oscillation; Olfactory center; PDZ domain; NADPH-diaphorase staining; Nonbursting neurons; Terrestrial slug; Limax;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of LRP1B-interacting proteins and inhibition of protein kinase Cα-phosphorylation of LRP1B by association with PICK1

Keywords: دامنه PDZ; LDL receptor family; LRP1B; LRP1; PICK1; JIP; PDZ domain; Protein kinase C;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions

Keywords: دامنه PDZ; GIRK; G-protein gated inwardly rectifying potassium channels; GPCR; G-protein coupled receptor; MDCK; Madin-Darby canine kidney; MUPP1; multiple PDZ domain protein 1; PDZ; PSD-95/discs large/ZO-1; PSD-95; postsynaptic density protein of 95 kDa; TER; tran

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications

Keywords: دامنه PDZ; nNOS; Nitric oxide; Neurogenesis; Excitotoxicity; PDZ domain; Depression; Alzheimer’s disease; Learning and memory; Parkinson’s disease

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Direct association of connexin36 with zonula occludens-2 and zonula occludens-3

Keywords: دامنه PDZ; Connexin36; Zonula occludens-2; Zonula occludens-3; PDZ domain; βTC-3 cells

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Genetic interaction between Neurexin and CAKI/CMG is important for synaptic function in Drosophila neuromuscular junction

Keywords: دامنه PDZ; Dneurexin; PDZ domain; Synaptic vesicle; Endocytosis; Neurotransmission

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

All-Atom Monte Carlo Approach to Protein–Peptide Binding

Keywords: دامنه PDZ; MC, Monte Carloprotein–protein interactions; protein dynamics; protein–peptide binding; computer simulation; PDZ domain

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum

Keywords: دامنه PDZ; synapse; NMDA receptor; PSD95; PDZ domain; syntaxin-1APMCA, plasma membrane calcium ATPase; PSD, post-synaptic density; PSW, pre-synapse web; SAP, synapse-associated protein

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Neuregulin signaling in neurons depends on ErbB4 interaction with PSD-95

Keywords: دامنه PDZ; PSD-95; PDZ domain; Neuregulin; ErbB4; Granule neuron; Neurite outgrowth

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains

Keywords: دامنه PDZ; NHERF1; EBP50; PDZ domain; Protein–protein interaction inhibitor; Indole; Small molecule

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Indole-2-amide based biochemical antagonist of Dishevelled PDZ domain interaction down-regulates Dishevelled-driven Tcf transcriptional activity

Keywords: دامنه PDZ; Dishevelled; Tcf; PDZ domain; Wnt; Indole; Anti-cancer; Apoptosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه