Keywords: دامنه PDZ; Prostacyclin receptor; Estrogen receptor; Sterol response element binding protein (SREBP); PDZK1(PDZ-domain-containing protein 1); IKEPP (intestinal and kidney enriched PDZ protein); C/EBP, CCAAT/enhancer binding protein; Rab11; Gene; Cardiovascular; AoSM
مقالات ISI دامنه PDZ (ترجمه نشده)
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Keywords: دامنه PDZ; AA; arachidonic acid; Aβ; fibrillar β-amyloid; ACC; acetyl-CoA carboxylase; Akt; protein kinase B; APP; amyloid precursor protein; ASAH2; neutral ceramidase; BA; benzyl alcohol; BBB; blood-brain-barrier; BMI; body mass index; BPM; bis(monoacylglycero)
Keywords: دامنه PDZ; NOS1AP; Nos1; PDZ domain; Dendrite development; Spine plasticity; Mouse;
HtrA3 is a cellular partner of cytoskeleton proteins and TCP1α chaperonin
Keywords: دامنه PDZ; CS; citrate synthase; ELISA; enzyme-linked immunosorbent assay; HtrA; High-temperature requirement A; MAPs; microtubule associated proteins; MST; MicroScale Thermophoresis; MT; microtubule; PD; protease domain; PDZ domain; postsynaptic density protein 95
Efficient synthesis of CN2097 using in situ activation of sulfhydryl group
Keywords: دامنه PDZ; CN2097; Disulfide; Fmoc/tBu; Polyarginine; PDZ domain; Solid-phase chemistry;
Optimization of the process of inverted peptides (PIPEPLUS) to screen PDZ domain ligands
Keywords: دامنه PDZ; SPOT synthesis; C-terminus; PDZ domain; Peptide array; Cellulose functionalization;
The role of the LB structural loop and its interactions with the PDZ domain of the human HtrA3 protease
Keywords: دامنه PDZ; HtrA; high temperature requirement A; PD; protease domain; PDZ domain; Postsynaptic density protein 95, Drosophila disc large tumor suppressor and Zonula occludens-1 protein domain; XIAP; X-linked Inhibitor of Apoptosis Protein; HtrA proteins; Human HtrA3
Structural insights into the activation mechanisms of human HtrA serine proteases
Keywords: دامنه PDZ; HtrA proteins; Serine proteases; Allosteric regulation; PDZ domain;
Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5
Keywords: دامنه PDZ; Dvl-1; PDZ domain; CXXC5; Wnt signaling; X-ray crystallography;
Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex
Keywords: دامنه PDZ; Arg1; Arginase 1; DH-PH domain; the diffuse B-cell lymphoma (Dbl) domain and pleckstrin-homology domain; GDP; guanosine diphosphate; GEF; guanine exchange factor; GM130; 130 kDa cis Golgi matrix protein; GTP; guanosine triphosphate; INF-γ; Interferonγ;
High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-Bas
Keywords: دامنه PDZ; Protein tyrosine phosphatase-Basophil; PDZ domain; Tandem-PH-domain-containing protein-1; Crystal structure; Binding specificity;
Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies
Keywords: دامنه PDZ; Dishevelled; PDZ domain; Pharmacophore; Wnt; Virtual screening; Docking; Surface plasmon resonance; Fluorescence spectroscopy;
Binding of PDZ domains to the carboxy terminus of inducible nitric oxide synthase boosts electron transfer and NO synthesis
Keywords: دامنه PDZ; iNOS; Reductase; Electron transfer; PDZ domain;
Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus
Keywords: دامنه PDZ; PDZ domain; Rabies virus; Neurons; Neuronal signaling; Phosphorylation; Enzymatic regulation; CytoG; C-terminal cytoplasmic tail of G protein; MAST2; microtubule-associated serine and threonine kinase 2; PBM; PDZ binding motif; PDZ; PSD-95/Dlg/ZO-1; PSD;
SAP97 blocks the RXR ER retention signal of NMDA receptor subunit GluN1-3 through its SH3 domain
Keywords: دامنه PDZ; ER; endoplasmic reticulum; IC; intermediate compartment; SAP97; NMDA; Receptor; Trafficking; PDZ domain; SH3 domain; RXR motif;
The role of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in depression: Central mediators of pathophysiology and antidepressant activity?
Keywords: دامنه PDZ; AMPA receptors; Ampakines; Ketamine; Psychiatric disorders; Depression; MDD; Glutamatergic synapse; PDZ domain; Synaptic plasticity; Neuroplasticity;
Structure-function analysis of SAP97, a modular scaffolding protein that drives dendrite growth
Keywords: دامنه PDZ; PDZ domain; GluA1; Spinal cord neuron;
Using a collection of MUPP1 domains to investigate the similarities of neurotransmitter transporters C-terminal PDZ motifs
Keywords: دامنه PDZ; Neurotransmitter transporters; PDZ motif; PDZ domain; MUPP1;
A thermodynamic study of the third PDZ domain of MAGUK neuronal protein PSD-95 reveals a complex three-state folding behavior
Keywords: دامنه PDZ; PDZ domain; Oligomeric intermediate; Differential scanning calorimetry; Three-state model; Thermodynamics; Protein folding;
DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis
Keywords: دامنه PDZ; Urogenital system; PDZ domain; Hydronephrosis;
PDZ affinity chromatography: A general method for affinity purification of proteins based on PDZ domains and their ligands
Keywords: دامنه PDZ; HaloTag; PDZ domain; Affinity chromatography; NMDA receptor; synGAP; Neuronal;
Ligand binding of PDZ domains has various roles in the synaptic clustering of SAP102 and PSD-95
Keywords: دامنه PDZ; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionate; DIV; day in vitro; EGFP; enhanced green fluorescent protein; MAGUK; membrane-associated guanylate kinase; PBS; phosphate-buffered saline; PDZ; PSD-95/discs large/zona occludens-1; PSD; postsynaptic
Modulatory roles of NHERF1 and NHERF2 in cell surface expression of the glutamate transporter GLAST
Keywords: دامنه PDZ; PDZ; PSD-95/Drosophila discs-large protein/zonula occludens protein; NHERF; Na+/H+ exchanger regulatory factor; ER; endoplasmic reticulum; ERGIC; ER-Golgi intermediated compartment; EGFP; enhanced green fluorescent protein; COPII; coatomer protein compl
Biochemical and structural insights into intramembrane metalloprotease mechanisms
Keywords: دامنه PDZ; S2P; site-2 protease; PDZ; (PSD-95, DLG, ZO-1); CBS; (cystathionine-β-synthase); IP(s); intramembrane protease(s); SREBP(s); sterol-regulatory element-binding protein(s); TMS(s); transmembrane segment(s); IMMP(s); intramembrane metalloprotease(s); RNAP;
Homer proteins accelerate Ca2+ clearance mediated by the plasma membrane Ca2+ pump in hippocampal neurons
Keywords: دامنه PDZ; Homer; PMCA; PDZ domain; Ca2+ signaling; Hippocampal neuron
NMR evaluation of interactions between substituted-indole and PDZ1 domain of PSD-95
Keywords: دامنه PDZ; PDZ domain; Protein–protein interaction; PSD-95; Analgesia
Irving Page Lecture: 5-HT2A serotonin receptor biology: Interacting proteins, kinases and paradoxical regulation
Keywords: دامنه PDZ; PDZ domain; Functional selectivity; Antipsychotic; Psychoactive; RSK2; Caveolin;
Solution structure of HtrA PDZ domain from Streptococcus pneumoniae and its interaction with YYF–COOH containing peptides
Keywords: دامنه PDZ; Streptococcus pneumoniae; HtrA; PDZ domain; NMR; Peptide-binding module
Synthesis and evaluation of bidentate ligands designed to interact with PDZ domains
Keywords: دامنه PDZ; CDI; carbonyldiimidazole; Cyc; cyclohexane; DABCO; diazabicyclooctane; DCM; dichloromethane; DIEA; diisopropylethylamine; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; EDC; 1-ethyl-3-(3-dimethylamino propyl)carbodiimide; EtOAc; ethylacetate;
The structural basis of mode of activation and functional diversity: A case study with HtrA family of serine proteases
Keywords: دامنه PDZ; HtrA; PDZ domain; Active site; Protease; Chaperone
Design, synthesis, structure and binding properties of PDZ binding, cyclic β-finger peptides
Keywords: دامنه PDZ; NMR; Peptide structure; Cyclic peptides; PDZ domain; Ligand binding; ITC; Peptide synthesis
dGIPC is required for the locomotive activity and longevity in Drosophila
Keywords: دامنه PDZ; DA, dopaminergic; GAIP, Gα interacting protein; TH, tyrosine hydroxylase; GIPC, GAIP interacting protein, C terminus; GPCR, G-protein coupled receptorP element mutagenesis; Central nervous system; Lifespan; Glia; PDZ domain; Drosophila
Sphingosine-1-phosphate receptor S1P1 is regulated by direct interactions with P-Rex1, a Rac guanine nucleotide exchange factor
Keywords: دامنه PDZ; Sphingosine-1-phosphate; S1P1; P-Rex1; Cell migration; PDZ domain
Differential roles of GRIP1a and GRIP1b in AMPA receptor trafficking
Keywords: دامنه PDZ; Synaptic plasticity; LTD; Palmitoylation; Glutamate; PDZ domain;
Hypoxia induces the PDZ domain-containing syntenin in the marine teleost Paralichthys olivaceus
Keywords: دامنه PDZ; Syntenin; PDZ domain; Hypoxia; Olive flounder; Paralichthys olivaceus
Chlamydial protease CT441 interacts with SRAP1 co-activator of estrogen receptor α and partially alleviates its co-activation activity
Keywords: دامنه PDZ; Chlamydiaceae; Estrogen receptor α; Steroid receptor RNA activator 1; PDZ domain; CT441 protease;
Reversible hydrogel formation driven by protein–peptide–specific interaction and chondrocyte entrapment
Keywords: دامنه PDZ; Chondrocyte; CutA; Hydrogel; Interaction; TIP1; PDZ domain
Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization
Keywords: دامنه PDZ; PICK1; PDZ domain; Phosphorylation; AMPA receptor; Protein trafficking;
Different domains of C. elegans PAR-3 are required at different times in development
Keywords: دامنه PDZ; Cell polarity; PAR-3; Phosphorylation; PDZ domain
A novel nitric oxide synthase expressed specifically in the olfactory center
Keywords: دامنه PDZ; Nitric oxide synthase; Procerebrum; Local field potential oscillation; Olfactory center; PDZ domain; NADPH-diaphorase staining; Nonbursting neurons; Terrestrial slug; Limax;
Identification of LRP1B-interacting proteins and inhibition of protein kinase Cα-phosphorylation of LRP1B by association with PICK1
Keywords: دامنه PDZ; LDL receptor family; LRP1B; LRP1; PICK1; JIP; PDZ domain; Protein kinase C;
Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions
Keywords: دامنه PDZ; GIRK; G-protein gated inwardly rectifying potassium channels; GPCR; G-protein coupled receptor; MDCK; Madin-Darby canine kidney; MUPP1; multiple PDZ domain protein 1; PDZ; PSD-95/discs large/ZO-1; PSD-95; postsynaptic density protein of 95Â kDa; TER; tran
Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications
Keywords: دامنه PDZ; nNOS; Nitric oxide; Neurogenesis; Excitotoxicity; PDZ domain; Depression; Alzheimer’s disease; Learning and memory; Parkinson’s disease
Direct association of connexin36 with zonula occludens-2 and zonula occludens-3
Keywords: دامنه PDZ; Connexin36; Zonula occludens-2; Zonula occludens-3; PDZ domain; βTC-3 cells
Genetic interaction between Neurexin and CAKI/CMG is important for synaptic function in Drosophila neuromuscular junction
Keywords: دامنه PDZ; Dneurexin; PDZ domain; Synaptic vesicle; Endocytosis; Neurotransmission
All-Atom Monte Carlo Approach to Protein–Peptide Binding
Keywords: دامنه PDZ; MC, Monte Carloprotein–protein interactions; protein dynamics; protein–peptide binding; computer simulation; PDZ domain
Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum
Keywords: دامنه PDZ; synapse; NMDA receptor; PSD95; PDZ domain; syntaxin-1APMCA, plasma membrane calcium ATPase; PSD, post-synaptic density; PSW, pre-synapse web; SAP, synapse-associated protein
Neuregulin signaling in neurons depends on ErbB4 interaction with PSD-95
Keywords: دامنه PDZ; PSD-95; PDZ domain; Neuregulin; ErbB4; Granule neuron; Neurite outgrowth
Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains
Keywords: دامنه PDZ; NHERF1; EBP50; PDZ domain; Protein–protein interaction inhibitor; Indole; Small molecule
Indole-2-amide based biochemical antagonist of Dishevelled PDZ domain interaction down-regulates Dishevelled-driven Tcf transcriptional activity
Keywords: دامنه PDZ; Dishevelled; Tcf; PDZ domain; Wnt; Indole; Anti-cancer; Apoptosis