Disruption of acute opioid dependence by antisense oligodeoxynucleotides targeting neurogranin
Keywords: Neurogranin; RC3; Opioid; Dependence; CaMKII; PKC
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Preservation of the pHi during ischemia via PKC by intermittent hypoxia
Keywords: Acidosis; Intermittent hypoxia adaptation; Ischemia; Reperfusion; PKC
Effect of NYD-SP27 down-regulation on ATP-induced Ca2+-dependent pancreatic duct anion secretion in cystic fibrosis cells
Keywords: NYD-SP27; Ca2+; PKC; CF; Short-circuit current;
Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
Keywords: ES cell; embryonic stem cell; p90RSK; p90 ribosomal S6 kinase; PDK1; 3â²-phosphoinositide-dependent protein kinase-1; PKC; protein kinase C; PKD; protein kinase D; S6K1; 70-kilodalton ribosomal S6 kinase 1; PDK1; PKD; PKC;
CSF-1 and TPA stimulate independent pathways leading to lysosomal degradation or regulated intramembrane proteolysis of the CSF-1 receptor
Keywords: Signal transduction; Protein-tyrosine kinase; RIPping; PKC; Macrophage; Ubiquitination
Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor α2 subunit expression, and PKC ζ activity
Keywords: GAD65; GAD67; GABA; PKC; Cocaine; Pergolide; Ondansetron; Nucleus accumbens; Caudate; Behavioral sensitization
Modulation of T-type Ca2+ channels by corticotropin-releasing factor through protein kinase C pathway in MN9D dopaminergic cells
Keywords: Corticotrophin-releasing factor; Dopamine neuron; Voltage-dependent Ca2+ channel; MN9D cells; Urocortin; PKC; T-type Ca2+ channel; Phorbol 12-myristate 13-acetate
Ionic involvement and kinase activity on the mechanism of nongenomic action of thyroid hormones on 45Ca2+ uptake in cerebral cortex from young rats
Keywords: Thyroid hormones; Calcium influx; Cerebral cortex; Calcium channels; PKC; PKA
Sphingosine 1-phosphate (S1P) inhibits monocyte-endothelial cell interaction by regulating of RhoA activity
Keywords: S1P; Atherosclerosis; Monocyte; PKC; RhoA;
After the Prestige oil spill modifications in NO production and other parameters related to the immune response were detected in hemocytes of Mytilus galloprovincialis
Keywords: CHX; cycloheximide; FCS; fetal calf serum; IL-2; interleukin-2; LPS; lipopolysaccharide; iNOS; inducible nitric oxide synthase; eNOs; endothelial nitric oxide synthase; mc-NOS; Mytilus constitutive nitric oxide synthase; mw-NOS; Mytilus winter nitric oxid
Munc18a: Munc-y business in mediating exocytosis
Keywords: APP; amyloid precursor protein; Cdk5; cyclin-dependent kinase 5; DOC2; double C2-domain; FRET; fluorescence resonance energy transfer; LDCV; large dense core vesicle; Mint; Munc18-interacting protein; PKC; protein kinase C; SM protein; Sec1/Munc18; SNARE;
Remnant lipoproteins stimulate proliferation and activate MAPK and Akt signaling pathways via G protein-coupled receptor in PC-3 prostate cancer cells
Keywords: PC; Prostate cancer; CM; chylomicrons; RLPs; remnant lipoproteins; MAPK; mitogen-activated protein kinase; EGFR; epidermal growth factor receptor; GPCR; G protein-coupled receptor; PKC; protein kinase C; PI3K; phosphoinositide 3-kinase; FBS; fetal bovine
Inhibition of protein kinase C protects against paraoxon-mediated neuronal cell death
Keywords: Paraoxon; PKC; Neurotoxicity; Neuroprotection; Cerebellar granule cell neurons; Pretreatment/post-treatment
Distinct involvement of p38-, ERK1/2 and PKC signaling pathways in C5a-mediated priming of oxidative burst in phagocytic cells
Keywords: Complement; C5a; Oxidative burst; Neutrophils; Monocytes; ERK1/2; p38; MAPK; PKC;
Effects of arsenic trioxide on the cellular proliferation, apoptosis and differentiation of human neuroblastoma cells
Keywords: Arsenic trioxide; Retinoic acid; Trk; Apoptosis; PKC;
Pain signalling pathways: From cytokines to ion channels
Keywords: NGF; nerve growth factor; TNFα; tumor necrosis factor α; IL-Iβ; interleukin 1β; PLCβ; phospholipase Cβ; PLA2; phospholipase A2; PKC; protein kinase C; TTX-R; tetrodotoxin-resistant; AA; arachidonic acid; PGE2; prostaglandin E2; COX; cyclooxygenase;
Activation of the nuclear transcription factor SP-1 by insulin rapidly increases the expression of protein kinase C delta in skeletal muscle
Keywords: Transcription factors; Insulin signaling; Gene transcription; PKC; SP-1; ChIP
Curcumin suppresses the transformation of an aryl hydrocarbon receptor through its phosphorylation
Keywords: Curcumin; AhR; Transformation; TCDD; PKC; Phosphorylation
Protein kinase C-dependent antilipolysis by insulin in rat adipocytes
Keywords: β-AR; β-adrenergic receptor; α-AR; α-adrenergic receptor; PKA; protein kinase A; PKC; protein kinase C; PKB; protein kinase B; PDK; phosphoinositide-dependent protein kinase; PI3K; phosphatidylinositol 3-kinase; PIP3; phosphatidylinositol 3,4,5-tripho
Targeted inhibition of glucuronidation markedly improves drug efficacy in mice—A model
Keywords: UDP-glucuronosyltransferase; Phosphorylation; Proof of principle; Immunosupression; Mycophenolic acid; CTL assay; Curcumin; Calphostin-C; PKC; Drug efficacy
Toxoplasma gondii possesses a receptor for activated C kinase ortholog
Keywords: RACK1; COPI; Toxoplasma; PKC; WD-repeats; Apicomplexan; Parasite
Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA
Keywords: PKC; Translocation; Localization; TPA; NIH3T3
Phosphorylation of connexin43 induced by Src: Regulation of gap junctional communication between transformed cells
Keywords: Cas; Crk associated substrate; CDC2; cell division cycle 2; CK1; casein kinase 1; Cx43; connexin43; MAPK; mitogen activated protein kinase; PKA; protein kinase A; PKC; protein kinase C; Connexins; Gap junctions; Cell communication; Src; Kinase; Signal tra
Peptide modulators of Src activity in G1 regulate entry into S phase and proliferation of NIH 3T3 cells
Keywords: Src; RACK1; PKC; Tyrosine kinases; G1/S transition; Cell cycle regulation;
One-trial in vitro conditioning regulates an association between the β-thymosin repeat protein Csp24 and actin
Keywords: actin-binding; excitability; protein kinase C; phosphorylation; beta-thymosin repeat protein; ASW; artificial sea water; CS; conditioned stimulus; Csp24; 24 kDa conditioned stimulus pathway phosphoprotein (accession number AAN08024); CV; column volume; GF
Chronic Administration of Carbamazepine Down-regulates AP-2 DNA-binding Activity and AP-2α Protein Expression in Rat Frontal Cortex
Keywords: AP-2; AP-2α; arachidonic acid; bipolar disorder; brain; carbamazepine; NF-κB; PKA; PKC; phospholipase A2; transcription factors
Distinct role of IL-3 promoter and enhancer region in murine mast cells
Keywords: PKC; protein kinase C; CAT; chloramphenicol acetyltransferase; PMA; phorbol 12-myristate 13-acetate; GM-CSF; granulocyte-macrophage colony-stimulating factor; CsA; cyclosporin A; TNF-α; tumor necrosis factor-α; DH site; DNase I-hypersensitive site; pIL3
Protein kinase C and alcohol addiction
Keywords: Ethanol; Alcoholism; PKC; GABA; Mice;
Effects of RACK1 on cell migration and IGF-I signalling in cardiomyoctes are not dependent on an association with the IGF-IR
Keywords: RACK1; IGF-IR; Src; PKC
Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats
Keywords: Anandamide; TRPV1; CGRP; PKC; Vasorelaxation; Septic shock
Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway
Keywords: KATP; Muscarinic M3 receptor; PKC; Verrucotoxin
Changes in function of NMDA receptor NR2B subunit in spinal cord of rats with neuropathy following chronic ethanol consumption
Keywords: Alcoholic neuropathy; Ethanol; NMDA receptor; NR2B subunit; PKC; Glutamate;
Role of diacylglycerol kinase in cellular regulatory processes: A new regulator for cardiomyocyte hypertrophy
Keywords: ANF; atrial natriuretic factor; DAG; diacylglycerol; DGK; diacylglycerol kinase; DGKζ-TG; transgenic mouse with cardiac specific expression of DGKζ; ERK; extracellular signal regulated kinase; ET-1; endothelin-1; GPCR; G protein-coupled receptor; MHC; m
Effect of diadenosine polyphosphates in achondroplasic chondrocytes: Inhibitory effect of Ap4A on FGF9 induced MAPK cascade
Keywords: MAPK; mitogen-activated protein kinase; ERK1/2; extracellular signal-regulated kinases 1 and 2; FGFR3; fibroblast growth factor receptor 3; FGF9; basic fibroblast growth factor 9; Ap3A; diadenosine triphosphate; Ap4A; diadenosine tetraphosphate; Ap5A; dia
Protease activation of calcium-independent phospholipase A2 leads to neutrophil recruitment to coronary artery endothelial cells
Keywords: AACOCF3; arachidonyl trifluoromethyl ketone; BEL; bromoenol lactone; BSA; bovine serum albumin; DAG; diacylglycerol; EDTA; ethylenediamine tetraacetic acid; EGTA; ethylen glycolbis(beta-amino-ethyl ether) tetraacetic acid; FCS; fetal calf serum; HCAEC; hu
Site specific phosphorylation of cytochrome c oxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion
Keywords: Cytochrome c oxidase; Subunit phosphorylation; Myocardial ischemia/reperfusion; Protein kinase A; Nano-LC-MS/MS analysis; CcO; cytochrome c oxidase; BNGE; blue native gel electrophoresis; PKA; protein kinase A; PKC; protein kinase C; ROS; reactive O2 sp
Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKCα
Keywords: PI 3-kinase; phosphoinositide 3-kinase; PKB; protein kinase B; PDK-1; phosphoinositide-dependent kinase-1; PKC; protein kinase C; mTOR; mammalian target of rapamycin; c48/80; compound 48/80; BAPTA; bis-(o-aminophemoxy)-ethane-N,N,Nâ²,Nâ²-tetraacetic aci
Evaluation of the role of Disabled-2 in nerve growth factor-mediated neurite outgrowth and cellular signalling
Keywords: 5, 7-DHT; 5, 7-dihydroxytryptamine; ApoER2; apolipoprotein E receptor 2; AR; androgen receptor; CNS; central nervous system; DAG; diacylglycerol; DAPI; 4â²,6-diamidino-2-phenylindole; LF2000; lipofectamine 2000; NGF; nerve growth factor; PAK; p21-activat
PACAP stimulates the sustained phosphorylation of tyrosine hydroxylase at serine 40
Keywords: BACC; bovine adrenal chromaffin cell; 8-CPT-6Phe-cAMP; 8-(4-chlorophenylthio)-N6-phenyladenosine-3â²,5â²-cyclic monophosphate; ERK1/2; extracellular signal-regulated protein kinase 1/2; 8-HA-cAMP; 8-n-hexylaminoadenosine-3â²,5â²-cyclic monophosphate;
Protein kinase C-alpha antagonizes apoptosis induction by histone deacetylase inhibitors in multidrug resistant leukaemia cells
Keywords: PKC; Protein kinase C; TSA; Trichostatin A; TPA; 12-O-tetradecanoyl-13-phorbol acetate; Pgp; P-Glycoprotein; DNM; Daunomycin; VRP; Varapamil; iHDACs; Histone deacetylase inhibitors; MDR; Multidrug resistance; SAHA; Suberoylanilide hydroxamic acid; Protein
Chronic ethanol exposure inhibits dopamine release via effects on the presynaptic actin cytoskeleton in PC12 cells
Keywords: Alcohol; PC12; Actin; Presynaptic; PKC
Signaling pathways involved in OxPAPC-induced pulmonary endothelial barrier protection
Keywords: PKC; PKA; Rac; FAK; Paxillin; Phosphorylation; Endothelium; Permeability; Actin; Cytoskeleton
Hormonal regulation of PKC: Estrogen up-regulates PKCη expression in estrogen-responsive breast cancer cells
Keywords: PKC; PKCη; 17-β-estradiol; Progesterone; MCF7; Breast cancer
On the participation of hippocampal PKC in acquisition, consolidation and reconsolidation of spatial memory
Keywords: memory; learning; consolidation; reconsolidation; PKC; hippocampusaPKC, atypical PKC; cPKC, conventional PKC; DAG, diacylglycerol; Gö6976, 12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrollo[3,4-c]carbazole; IA, inhibitory avoi
Peripheral metabotropic glutamate receptor 5 mediates mechanical hypersensitivity in craniofacial muscle via protein kinase C dependent mechanisms
Keywords: masseter; rat; behavioral model; glutamate; AUC; area under the curve; CPCCOEt; 7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxylate ethyl ester; DHPG; R,S-3,5-dihydroxyphenylglycol; DRG; dorsal root ganglia; EAA; excitatory amino acid; mGluR; metabotropic
Vasopressin-induced translocation and proteolysis of protein kinase Cα in an amphibian brain: Modulation by corticosterone
Keywords: CORT, corticosterone; IOD, integrated optical density; IP3, inositol 1,4,5 trisphosphate; MTr, mesotocin receptor; VTr, vasotocin receptorVasopressin; Vasotocin; Corticosterone; PKC; Proteolysis; Translocation
The inhibitory mechanism of methylmercury on differentiation of human neuroblastoma cells
Keywords: Methylmercury; Differentiation; Cell cycle; Retinoic acid; ERK; PKC
Signal transduction mechanisms of CD137 ligand in human monocytes
Keywords: ERK; extracellular signal-regulated kinase; MAPK; mitogen activated protein kinase; MEK; MAP/ERK kinase; PI3-K; Phosphoinositide-3-kinase; PKA; Protein kinase A; PKC; Protein kinase C.; Human; CD137 ligand; Monocytes; Signalling; Signal transduction;
Protein kinase C as a stress sensor
Keywords: PKC; protein kinase C; Cx43; connexin 43; C1B; region of diacylglycerol-binding domain of PKC; ROS; reactive oxygen species; Cx46; connexin 46; Cx50; connexin 50.; Protein kinase C epsilon; Protein kinase C gamma; Ischemia; heart; Neural tissues;
Calcium-dependent interactions of the human norepinephrine transporter with syntaxin 1A
Keywords: Transporter; Norepinephrine; Syntaxin; Calcium; Antidepressant; PKC