Measurement of cyclooxygenase inhibition using liquid chromatography–tandem mass spectrometry
Keywords: پروستاگلاندین E2; LC–MS–MS; COX-1; COX-2; Cyclooxygenase; Prostaglandin E2
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Salvianolic acid A suppress lipopolysaccharide-induced NF-κB signaling pathway by targeting IKKβ
Keywords: پروستاگلاندین E2; LPS; lipopolysaccharide; NO; nitric oxide; PGE2; prostaglandin E2; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; NF-κB; nuclear factor-kappa B; IκBα; inhibitory kappa B-α; IKKβ; IκB kinase β; IMAP-TR-FRET; immobilized metal affini
Prostaglandin E2-prostanoid EP3 signal induces vascular contraction via nPKC and ROCK activation in rat mesenteric artery
Keywords: پروستاگلاندین E2; Vascular smooth muscle; Prostaglandin E2; Prostanoid EP3 receptor; Prostanoid FP receptor; Prostanoid TP receptor; Protein kinase C;
Prostaglandin E2 increases cardiac fibroblast proliferation and increases cyclin D expression via EP1 receptor
Keywords: پروستاگلاندین E2; Prostaglandin E2; Fibroblast; Cyclin D; Proliferation;
An assay to evaluate heparanase procoagulant activity
Keywords: پروستاگلاندین E2; TF; tissue factor; TFPI; tissue factor pathway inhibitor; HS; heparan sulfate; CS; cesarean section; IUGR; intrauterine growth restriction; PGE2; prostaglandin E2; Heparanase; Tissue factor; Coagulation; Pregnancy;
Immunoregulatory function of bone marrow mesenchymal stem cells in EAE depends on their differentiation state and secretion of PGE2
Keywords: پروستاگلاندین E2; Adult bone marrow stem cells; Neural differentiation; Immunosuppression; Prostaglandin E2; Experimental autoimmune encephalomyelitis;
Antigenicity of Primary Endodontic Infection against Macrophages by the Levels of PGE2 Production
Keywords: پروستاگلاندین E2; Bacteria; endotoxin; macrophages; prostaglandin E2; root canal;
Prostaglandin E2 enhances IL-33 production by dendritic cells
Keywords: پروستاگلاندین E2; BMDC; bone marrow-derived dendritic cell; DC; dendritic cell; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GM-CSF; granulocyte-macrophage colony stimulating factor; IL; interleukin; LPS;
Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice
Keywords: پروستاگلاندین E2; Acute inflammation; Chelerythrine; Prostaglandin E2; Cyclooxygenase-2; Macrophages
Research ReportGlibenclamide ameliorates ischemia-reperfusion injury via modulating oxidative stress and inflammatory mediators in the rat hippocampus
Keywords: پروستاگلاندین E2; ATP; adenosine triphosphate; GSH; glutathione; IL-10; interleukin10; IR; ischemia-reperfusion; MPO; myeloperoxidase; NC(Ca-ATP) channel; Ca2+-activated [ATP]i-sensitive nonspecific cation channel; PGE2; prostaglandin E2; ROS; reactive oxygen species; SU
Acetylsalicylic acid as an augmentation agent in fluoxetine treatment resistant depressive rats
Keywords: پروستاگلاندین E2; Treatment resistant depression; Fluoxetine; Chronic unpredictable mild stress; Acetylsalicylic acid; Cyclooxygenase-2; Prostaglandin E2;
Nitric oxide counteracts the hyperoxia-induced proliferation and proinflammatory responses of mouse astrocytes
Keywords: پروستاگلاندین E2; ACM; astrocyte conditioned medium; ApoE; apolipoprotein E; ApoJ/clusterin; apolipoprotein J; CNS; central nervous system; GFAP; glial fibrillary acidic protein; PCNA; proliferating cell nuclear antigen; PGE2; prostaglandin E2; Nitric oxide; Oxygen; Astroc
Involvement of the constitutive prostaglandin E synthase cPGES/p23 in expression of an initial prostaglandin E2 inactivating enzyme, 15-PGDH
Keywords: پروستاگلاندین E2; PG; prostaglandin; cPGES; cytosolic PGE synthase; 15-PGDH; 15-hydroxyprostaglandin dehydrogenase; mPGES; membrane-bound PGE synthase; COX; cyclooxygenase; PLA2; phospholipase A2; IL-1β; interleukin-1β; Prostaglandin E2; Cytosolic prostaglandin E synthas
Anti-ovulatory effects of RU486 and trilostane involve impaired cyclooxygenase-2 expression and mitotic activity of follicular granulosa cells in rats
Keywords: پروستاگلاندین E2; Progesterone; Cyclooxygenase-2; Prostaglandin E2; Ovulation; Follicular granulosa cell
Central PGE2 exhibits anxiolytic-like activity via EP1 and EP4 receptors in a manner dependent on serotonin 5-HT1A, dopamine D1 and GABAA receptors
Keywords: پروستاگلاندین E2; Anxiolytic activity; Prostaglandin E2; EP1 receptor; EP4 receptor; Serotonin 5-HT1A receptor; Dopamine D1 receptor; GABAA receptor;
Evidence for the presence of a critical disulfide bond in the mouse EP3γ receptor
Keywords: پروستاگلاندین E2; mEP3γ; mouse E-prostanoid receptor subtype 3 gamma; PGE2; prostaglandin E2; HA; hemagglutinin epitope tag; Prostaglandin E2; Mutagenesis; Cysteine; Disulfide bond; GPCRs;
Induction of integrin β3 in PGE2-stimulated adhesion of mastocytoma P-815 cells to the Arg-Gly-Asp-enriched fragment of fibronectin
Keywords: پروستاگلاندین E2; Mastocytoma P-815 cells; Prostaglandin E2; Adhesion; Integrin; Fibronectin
Non-antibacterial tetracyclines modulate mediators of periodontitis and atherosclerotic cardiovascular disease: A mechanistic link between local and systemic inflammation
Keywords: پروستاگلاندین E2; ACS; acute coronary syndrome; AMI; acute myocardial infarction; Apo; apolipoprotein; ASCVD; atherosclerotic cardiovascular disease; CMT; chemically modified tetracycline; CP; chronic periodontitis; CRP; C-reactive protein; GCF; gingival crevicular fluid;
Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways
Keywords: پروستاگلاندین E2; AS; Angelica sinensis; LPS; lipopolysaccharide; NO; nitric oxide; PGE2; prostaglandin E2; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; NF-κB; nuclear factor κB; AP-1; activator protein-1; TNF-α; tumor necrosis factor-α; iROS; intrac
The regulation of CD4+ T cell immune responses toward Th2 cell development by prostaglandin E2
Keywords: پروستاگلاندین E2; Prostaglandin E2; CD4+ T cell; Immune responses; Cytokine;
Central interleukin-10 attenuated lipopolysaccharide-induced changes in core temperature and hypothalamic glutamate, hydroxyl radicals and prostaglandin-E2
Keywords: پروستاگلاندین E2; Fever; Lipopolysaccharide; Glutamate; Hydroxyl radicals; Prostaglandin E2; Interleukin-10;
Ibuprofen bioconcentration and prostaglandin E2 levels in the bluntnose minnow Pimephales notatus
Keywords: پروستاگلاندین E2; NSAIDs; Ibuprofen; Eicosanoids; Prostanoids; Prostaglandin E2; Bluntnose minnows LC/MS/MS; GC/MS
Enhancement of carbachol-induced amylase secretion in parotid glands from rats with experimental periodontitis
Keywords: پروستاگلاندین E2; PGE2; prostaglandin E2; 4-DAMP; 4-diphenylacetoxy-N-mthylpiperidine methiodide; U-73122; 1-6-17β-3-methoxgestra-1,3,5-10-trine-17yl-aminoheyil-1-H-pirrole-2,5-dione; SQ 22536; 9-(tetrhydro-2furanyl)-9H-purin-6 amine IP3inositol 1,4,5-triphosphate; PKC; p
Activation of the EP4 prostanoid receptor induces prostaglandin E2 and pro-inflammatory cytokine production in human airway epithelial cells
Keywords: پروستاگلاندین E2; Prostaglandin E2; Airway epithelia; EP4 receptor; Cytokine; Calu-3 cell; Inflammation
Using 18F-FDG microPET imaging to measure the inhibitory effects of Clematis chinensis Osbeck on the pro-inflammatory and degradative mediators associated with inflammatory arthritis
Keywords: پروستاگلاندین E2; Clematis chinensis Osbeck; Chondrocytes; Prostaglandin E2; Metalloproteinase; Lipopolysaccharide; Arthritis; Positron emission tomography
Gastroprotective and safety effects of WIN-34B, a novel treatment for osteoarthritis, compared to NSAIDs
Keywords: پروستاگلاندین E2; Lonicera japonica Thunb.; Anemarrhena asphodeloides Bunge; Gastric ulcer; Prostaglandin E2; Leukotriene B4
Evidence that PGE2 in the dorsal and median raphe nuclei is involved in LPS-induced anorexia in rats
Keywords: پروستاگلاندین E2; 8-OH-DPAT; 8-hydroxy-N,N-dipropyl-2-aminotetralin; A1; A1 area of the ventrolateral medulla; APR; acute-phase response; Arc; arcuate nucleus of the hypothalamus; CeA; central nucleus of the amygdala; COX; cyclooxygenase; CRH; corticotropin-releasing hormo
Nitroxides prevent exacerbation of indomethacin-induced gastric damage in adjuvant arthritis rats
Keywords: پروستاگلاندین E2; AA; adjuvant arthritis; CINC; cytokine-induced neutrophil chemoattractant; COX; cyclooxygenase; DA; Dark Agouti; ESR; electron spin resonance; FOV; field of view; IL; interleukin; NMR; nuclear magnetic resonance; NSAID; nonsteroidal anti-inflammatory drug
Effects of specific prostanoid EP receptor agonists on cell proliferation and intracellular Ca2+ concentrations in human airway smooth muscle cells
Keywords: پروستاگلاندین E2; Airway smooth muscle; Asthma; Calcium; Prostaglandin E2; Prostanoid receptor; Remodeling
Glial cells isolated from dorsal root ganglia express prostaglandin E2 (EP4) and prostacyclin (IP) receptors
Keywords: پروستاگلاندین E2; cAMP; Dorsal root ganglia; EP4 receptors; IP receptors; Prostaglandin E2; Satellite glial cells
Cantharidin modulates development of human monocyte-derived dendritic cells
Keywords: پروستاگلاندین E2; APCs; professional antigen-presenting cells; CFSE; carboxyfluorescein succinimidyl ester; CTD; cantharidin; DCs; dendritic cells; FITC; fluorescein isothiocyanate; GI; gastrointestinal tract; IFN-γ; interferon-γ; IL-4; interleukin-4; PP1; protein phosph
Platonin Mitigates Acute Lung Injury Induced by Bilateral Lower Limb Ischemia-Reperfusion in Rats
Keywords: پروستاگلاندین E2; chemokine; cytokine; nitric oxide; prostaglandin E2
Sodium dl-α-tocopheryl-6-O-phosphate inhibits PGE2 production in keratinocytes induced by UVB, IL-1β and peroxidants
Keywords: پروستاگلاندین E2; 1; sodium dl-α-tocopheryl-6-O-phosphate; 2; dl-α-tocopheryl acetate; 3; dipotassium glycyrrhizin acid; Toc; dl-α-tocopherol; PGE2; prostaglandin E2; HPLC; high-pressure liquid chromatography, UVB, ultraviolet B; IL-1β; interleukin-1beta; tBHP; tert-bu
Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model
Keywords: پروستاگلاندین E2; COX; cyclooxygenase; d; day; DMS; dimethyl sulfide; DMSO; dimethyl sulfoxide; DMSO2; methyl sulfone; IBD; inflammatory bowel disease; ICAM-1; intercellular adhesion molecule 1; IFNGR1; interferon gamma receptor 1; IECs; intestinal epithelial cells; IL; in
ReviewProstanoid signaling: Dual role for prostaglandin E2 in neurotoxicity
Keywords: پروستاگلاندین E2; Prostaglandin E2; E Prostanoid receptor; Arachidonic acid; Neurotoxicity; Neuroinflammation;
Differential central pain processing following repetitive intramuscular proton/prostaglandin E2 injections in female fibromyalgia patients and healthy controls
Keywords: پروستاگلاندین E2; Fibromyalgia; fMRI; Tonic and transient muscle pain; Prostaglandin E2; Proton;
The pharmacology and activity of non-steroidal anti-inflammatory drugs (NSAIDs): a review of their use as an adjuvant treatment in patients with HBV and HCV chronic hepatitis
Keywords: پروستاگلاندین E2; Prostaglandin E2; Hepatitis B Virus; Hepatitis C Virus; Chronic hepatitis; Non-steroidal anti-inflammatory drugs (NSAIDs);
Reduced expression of COXs and production of prostaglandin E2 in patients with nasal polyps with or without aspirin-intolerant asthma
Keywords: پروستاگلاندین E2; Aspirin intolerance; asthma; chronic rhinosinusitis; cyclooxygenase; fibroblast; nasal mucosa; nasal polyp; prostaglandin E2; α-smooth muscle actin; AA; Arachidonic acid; AI; Aspirin intolerant; AIA; Aspirin-intolerant asthma; AT; Aspirin tolerant; ATA;
Extract of the dried heartwood of Caesalpinia sappan L. attenuates collagen-induced arthritis
Keywords: پروستاگلاندین E2; Caesalpinia sappan L.; Collagen-induced arthritis; Cytokines; Prostaglandin E2; Cyclooxygenase-2; NF-κB
The inducible prostaglandin E synthase mPGES-1 regulates growth of endometrial tissues and angiogenesis in a mouse implantation model
Keywords: پروستاگلاندین E2; Prostaglandin E2; MPGES-1; COX-2; Endometriosis; Angiogenesis
Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system
Keywords: پروستاگلاندین E2; Dienogest; Prostaglandin E2; Cyclooxygenase-2; Microsomal prostaglandin E2 synthase-1; Aromatase; Endometrial epithelial cells
PGE1 and PGE2 modify platelet function through different prostanoid receptors
Keywords: پروستاگلاندین E2; Prostaglandin E2; Prostaglandin E1; EP receptors; Platelet function; P-selectin; VASP phosphorylation
Macrophage migration inhibitory factor activates cyclooxygenase 2-prostaglandin E2 in cultured spinal microglia
Keywords: پروستاگلاندین E2; CNS; central nervous system; COX 2; cyclooxygenase 2; ERK; extracellular signal regulated kinase; ISO-1; ((S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester; MAPK; mitogen activated protein kinase; MIF; macrophage migration inhibi
Heme Oxygenase-1 Mediates the Protective Effects of Ischemic Preconditioning on Mitigating Lung Injury Induced by Lower Limb Ischemia-Reperfusion in Rats
Keywords: پروستاگلاندین E2; heme oxygenase; chemokine; cytokine; nitric oxide; prostaglandin E2
Sodium butyrate induces the production of cyclooxygenases and prostaglandin E2 in ROS 17/2.8 osteoblastic cells
Keywords: پروستاگلاندین E2; Butyric acid; Osteoblast; Prostaglandin E2; Type I collagen; Osteopontin;
Nitric oxide stimulates progesterone and prostaglandin E2 secretion as well as angiogenic activity in the equine corpus luteum
Keywords: پروستاگلاندین E2; Corpus luteum; Nitric oxide; Progesterone; Prostaglandin E2; Angiogenesis
Tumor necrosis factor-α inhibits the stimulatory effect of luteinizing hormone and prostaglandin E2 on progesterone secretion by the bovine corpus luteum
Keywords: پروستاگلاندین E2; Tumor necrosis factor-α; Progesterone; Luteinizing hormone; Prostaglandin E2; Bovine corpus luteum;
Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation
Keywords: پروستاگلاندین E2; indoleamine-2,3-dioxygenase; interleukin-17; mesenchymal stromal cells; prostaglandin E2; regulatory T cells; Th17
The soluble EP2 receptor FuEP2/Ex2 suppresses endometrial cancer cell growth in an orthotopic xenograft model in nude mice
Keywords: پروستاگلاندین E2; Prostaglandin E2; EP2 receptor; Decoy receptor; Endometrial cancer
A phospholipase A2 from Bothrops asper snake venom activates neutrophils in culture: Expression of cyclooxygenase-2 and PGE2 biosynthesis
Keywords: پروستاگلاندین E2; Neutrophil; Myotoxin-III; Phosholipase A2; Cyclooxygenase; Prostaglandin E2;