Keywords: پروتئین کیناز D; Thyroid hormones; 3, 5-Diiodothyronine; 3-Iodothyronamine; Thyroacetic acids; Non-genomic effects; Cardioprotection; ADP; adenosine diphosphate; Akt; Ak strain transforming; Ang II; angiotensin II; ATP; adenosine triphosphate; CaM; calmodulin; D2; type II
مقالات ISI پروتئین کیناز D (ترجمه نشده)
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Keywords: پروتئین کیناز D; 7AAD; 7-aminoactinomycin D; αSMA; alpha smooth muscle actin; AKT; protein kinase B; ALK; activin receptor-like kinase; Ang; angiopoietin; Ang II; angiotensin II; BCRP1; breakpoint cluster region pseudogene; bFGF; basic fibroblast growth factor; C1P; cera
Keywords: پروتئین کیناز D; Peripheral blood mononuclear cells; AMP-activated protein kinase; Postprandial lipemia; Nuclear factor-κB; ACC; Acetyl-CoA carboxylase; AICAR; 5-Aminoimidazole-4-carboxamide ribonucleotide; AMPK; AMP activated protein kinase; ANOVA; Analysis of variance;
Keywords: پروتئین کیناز D; AMPK; AMP-activated protein kinase; Angptl-4; Angiopoietin-like protein 4; D55; Inject animals with 55Â mg/kg through tail vein; D100; Inject animals with 100Â mg/kg through tail vein; EC; Endothelial cell; ECCM; Endothelial cell conditioned medium; ER; E
Keywords: پروتئین کیناز D; βAla; βalanine; Bantag-1; selective BRS-3 peptide antagonist; Bn; bombesin; BnR; bombesin receptor; BRS-3(BB3); bombesin receptor subtype 3; COOH terminus; carboxyl terminus; CCK; cholecystokinin; CNS; central nervous system; Cpa; chlorophenylalanine; D
Keywords: پروتئین کیناز D; Aldosterone; Kidney; Epithelial sodium channel; Protein kinase D
Keywords: پروتئین کیناز D; ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: پروتئین کیناز D; ALP; alkylphospholipid; ASK1; apoptosis signal-regulating kinase 1; CT; CTP:phosphocholine cytidylyltransferase; DISC; death-inducing signaling complex; EGF; epidermal growth factor; ER; endoplasmic reticulum; ERK; extracellular-signal-regulated kinase; J
Nanobodies targeting cortactin proline rich, helical and actin binding regions downregulate invadopodium formation and matrix degradation in SCC-61 cancer cells
Keywords: پروتئین کیناز D; Abl; ableson kinase; ABR; actin binding repeat; Arg; ableson related gene kinase; Arp2/3; actin related protein 2/3; ATAT1; alpha-tubulin N-acetyltransferase 1; DMEM; Dulbecco's modified Eagle's medium; DOX; doxycycline; Erk; extracellular signal-re
Sec6 enhances cell migration and suppresses apoptosis by elevating the phosphorylation of p38 MAPK, MK2, and HSP27
Keywords: پروتئین کیناز D; Sec6; p38 MAPK; MK2; HSP27; MAPK; Mitogen-activated protein kinases; MAP3K; MAPK kinase kinase; MAP2K; MAPK kinase; TAK1; TGFβ-activated kinase 1; ASK1; apoptosis signal-regulating kinase 1; MLK; mixed-lineage kinase; CREB; cAMP response element binding
ROS signalling in the biology of cancer
Keywords: پروتئین کیناز D; AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel
Bradykinin stimulates protein kinase D-mediated colonic myofibroblast migration via cyclooxygenase-2 and heat shock protein 27
Keywords: پروتئین کیناز D; Bradykinin; Protein kinase D; Myofibroblast; COX-2; Hsp27;
ReviewProtein kinase D signaling in cancer: A friend or foe?
Keywords: پروتئین کیناز D; PKC; protein kinase C; PKD; protein kinase D; PLC; phospholipase C; DAG; diacylglycerol; CRD; cysteine-rich domain; GPCR; G protein-coupled receptor; TNF; tumor necrosis factor; TGN; trans-Golgi network; EMT; epithelial-to-mesenchymal transition; MMP; mat
Mechanisms of the amplifying pathway of insulin secretion in the β cell
Keywords: پروتئین کیناز D; ABCC8; ATP binding cassette subfamily C member 8; ADCY5; adenylyl cyclase type 5; AICAR; 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; DPP-IV; dipeptidyl peptidase 4; G6PD; glucose-6-phosphate dehydrogenase; GDH; glutamate dehydrogenase; GIP; gast
Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP
Keywords: پروتئین کیناز D; BCl3; boron trichloride; CAN; ceric ammonium nitrate; DAG; diacylglycerol; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DMAP; 4-dimethylaminopyridine; GEFs; guanine nucleotide exchange factors; LiHMDS; lithium hexamethyldisilazide; MRCKs; myotonic dystrophy k
Phos-tag SDS-PAGE resolves agonist- and isoform-specific activation patterns for PKD2 and PKD3 in cardiomyocytes and cardiac fibroblasts
Keywords: پروتئین کیناز D; (CREB); cAMP response element binding protein; (ET-1); endothelin-1; (NE); norepinephrine; (PMA); phorbol 12-myristate 13-acetate; (Phos-tag); Phosphate binding tag; (PDGF); platelet-derived growth factor; (PH domain); pleckstrin homology domain; (PAGE);
The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events
Keywords: پروتئین کیناز D; CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; PAK; p21-activated kinases; SFK; Src family of kinases; PKC; protein kinase C; PYK2; proline-rich tyrosine kinase 2; FAK; focal adhesion kinase; SHC; Src homolog
Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis
Keywords: پروتئین کیناز D; CHK; CSK (C-terminal Src kinase)-homologous kinase; CLK; Cdc2-like kinase; HIPK; homeodomain-interacting protein kinase; PIM; proviral integration of moloney murine leukemia virus; PKD; protein kinase D; FLT; Fms-like tyrosine kinase; CDK; cyclin-dependen
Irbesartan ameliorates diabetic cardiomyopathy by regulating protein kinase D and ER stress activation in a type 2 diabetes rat model
Keywords: پروتئین کیناز D; Diabetic cardiomyopathy; Irbesartan; Protein kinase D; Endoplasmic reticulum stressARB, angiotensin II receptor blocker; Bax, bcl2-associated X protein; Bcl-2, b-cell lymphoma/leukemia-2; CAMK, calcium/calmodulin-dependent protein kinase; DCM, diabetic ca
Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity
Keywords: پروتئین کیناز D; Protein kinase D; Functional redundancy; Neuronal polarity; Knockout mouse;
Gastrointestinal hormones/neurotransmitters and growth factors can activate P21 activated kinase 2 in pancreatic acinar cells by novel mechanisms
Keywords: پروتئین کیناز D; CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; PAKs; p21-activated kinases; SFK; Src family of kinases; PKC; protein kinase C; PYK2; proline-rich tyrosine kinase 2; FAK; focal adhesion kinase; PKD; protein ki
UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy
Keywords: پروتئین کیناز D; PDEs; phosphodiesterases; AKAP; A-kinase anchoring protein; cAMP; 3â²,5â²-cyclic monophosphate; Epac; exchange protein directly activated by cAMP; PKA; protein kinase A; PKC; protein kinase C; PKD; protein kinase D; UCR; upstream conserved region; β-AR
PAQR3 regulates Golgi vesicle fission and transport via the Gβγ-PKD signaling pathway
Keywords: پروتئین کیناز D; PAQR; progestin and adipoQ receptor; RKTG; Raf kinase trapping to the Golgi; PKD; protein kinase D; PM; plasma membrane; VSV-G; vesicular stomatitis virus-glycoprotein; Heterotrimeric G protein; Golgi; Membrane transport; Vesicle trafficking; Non-canonica
Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology
Keywords: پروتئین کیناز D; AAV; adeno-associated virus; AON; antisense oligonucleotide; bp; base pair; Ca2+; Â calcium; CaMKII; Ca2+/calmodulin-dependent kinase II; Chr; chromosome; CK2; casein kinase 2; CMH4; hypertrophic cardiomyopathy, locus 4; cMyBP-C; cardiac myosin-binding pr
Pro- and anti-inflammatory effects of histamine on tissue factor and TNFα expression in monocytes of human blood
Keywords: پروتئین کیناز D; ASA; acetylsalicylic acid; FV; Factor V; FVIIa; activated Factor VII; FXa; activated Factor X; LPS; lipopolysaccharide; TF; tissue factor; PMA; phorbol myristate acetate; PKC; protein kinase C; PKD; protein kinase D; PSGL-1; P-selectin glycoprotein-1; TNF
Protein kinase C and Src family kinases mediate angiotensin II-induced protein kinase D activation and acute aldosterone production
Keywords: پروتئین کیناز D; Adrenal glomerulosa; Aldosterone; Protein kinase D (PKD); Angiotensin II (AngII); Protein kinase C (PKC); Src family kinases; AngII; angiotensin II; DAG; diacylglycerol; PKD; protein kinase D; ZG; zona glomerulosa; PKC; protein kinase C; KRB+; bicarbonate
Protein kinase D1 deficiency promotes differentiation in epidermal keratinocytes
Keywords: پروتئین کیناز D; Differentiation; Keratinocyte; Proliferation; Protein kinase D; Transglutaminase
Protein kinase-D1 overexpression prevents lipid-induced cardiac insulin resistance
Keywords: پروتئین کیناز D; AMPK; AMP-activated protein kinase; AW; anterior wall; BNP; B-type natriuretic peptide; caPKD1; cardiospecific constitutively active PKD1 overexpression; DAG; diacylglycerol; EFS; electric field stimulation; [18F]FDG; [18F]fluoro-deoxyglucose; [18F]FTHA;
Modeling sphingomyelin synthase 1 driven reaction at the Golgi apparatus can explain data by inclusion of a positive feedback mechanism
Keywords: پروتئین کیناز D; Feedback control; Sphingomyelin synthase 1; Sphingomyelin synthesis; Cer; ceramide; CHO Cells; Chinese hamster ovary cells; DAG; diacylglycerol; ER; endoplasmic Reticulum; IFT; implicit function theorem; PC; phosphatidylcholine; PH Domain; pleckstrin homo
PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription
Keywords: پروتئین کیناز D; AP1; activator protein 1; cpm; counts per minute; EMSA; electrophoretic mobility shift assay; FACS; fluorescence activated cell sorter; ERK; extracellular regulated kinase; IL-2; interleukin-2; IFNγ; interferon gamma; IκB; inhibitor of NFκB; IKK; IκB
Diet-induced obesity causes long QT and reduces transcription of voltage-gated potassium channels
Keywords: پروتئین کیناز D; Obesity; Arrhythmia; Cyclic AMP response element binding protein; Kv1.5; Protein kinase D;
Overexpression of AMP-activated protein kinase or protein kinase D prevents lipid-induced insulin resistance in cardiomyocytes
Keywords: پروتئین کیناز D; Cardiac metabolism; Lipid accumulation; Insulin resistance; AMPK; Protein kinase D; Treatment;
Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response
Keywords: پروتئین کیناز D; NF-κB; nuclear factor-κB; UV; ultraviolet; IκB; inhibitor of NF-κB; IKK; IκB kinase; NEMO; NF-κB essential modulator; TNFR; tumor necrosis factor receptor; IL-1R; interleukin-1 receptor; NIK; NF-κB inducing kinase; LPS; lipopolysaccharide; PKD; pro
Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks
Keywords: پروتئین کیناز D; ARF; ADP-ribosylation factor; DAG; diacylglycerol; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; FAPP2; Four-phosphate adaptor protein 2; FAAT motif; two phenylalanines in an acidic tract motif; GPCR; G-p
Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: Selective stimulation of PKD Ser748 autophosphorylation by Gαq
Keywords: پروتئین کیناز D; PKC; protein kinase C; PKD; protein kinase D; GPCR; G protein-coupled receptor; Gα; heterotrimeric G protein alpha subunit; PLC; phospholipase C; CAMK; Ca2 +/calmodulin-dependent protein kinase; AlF4â; aluminum fluoride; GFP; enhanced green fluorescen
Role of phospholipase Cε in physiological phosphoinositide signaling networks
Keywords: پروتئین کیناز D; PLC; phosphoinositide-specific phospholipase C; PKC; protein kinase C; LPA; lysophosphatidic acid; S1P; sphingosine-1 phosphate; Epac; Exchange protein directly activated by cAMP; GPCR; G protein-coupled receptor; GEF; guanine nucleotide exchange factor;
Distinctive roles of PLD signaling elicited by oxidative stress in synaptic endings from adult and aged rats
Keywords: پروتئین کیناز D; Phospholipase D; Protein kinase D; Oxidative injury; Aging; Diacylglycerol; Membrane microdomain
Protein kinase D regulates the human cardiac L-type voltage-gated calcium channel through serine 1884
Keywords: پروتئین کیناز D; Human voltage-gated calcium channel; Protein kinase D;
3,5-Diarylazoles as novel and selective inhibitors of protein kinase D
Keywords: پروتئین کیناز D; Kinase inhibitor; PKD; Protein kinase D; Histone deacetylase; Heart failure; Cardiac hypertrophy
The δA isoform of calmodulin kinase II mediates pathological cardiac hypertrophy by interfering with the HDAC4-MEF2 signaling pathway
Keywords: پروتئین کیناز D; CaMKII; Ca2+/calmodulin-activated kinase II; HDAC; histone deacetylase; MEF2; myocyte enhancer factor-2; CaN; calcineurin; NFAT; nuclear factor of activated T-cell; PKD; protein kinase D; ANF; atrial natriuretic factor; βMHC; β-myosin heavy chain; NRVM;
Protein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2: A common pathway to the ABCA1 gene regulation
Keywords: پروتئین کیناز D; Protein kinase D; Activator protein 2; Adiponectin; ABCA1; HDL;
PKCθ activation in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors is needed for stimulation of numerous important cellular signaling cascades
Keywords: پروتئین کیناز D; CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; GI; gastrointestinal; CCK-JMV; CCK-JMV-180; IP; immunoprecipitation; Co-IP; co-immunoprecipitation; PKD; protein kinase D; GPCR; G protein-coupled receptor; PYK2
Chemical modifications of resveratrol for improved protein kinase C alpha activity
Keywords: پروتئین کیناز D; PKC; protein kinase C; DAG; diacylglycerol; TPA; 12-O-tetradecanoylphorbol-13-acetate; PDB; protein data bank; NMR; nuclear magnetic resonance; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HEK; human embryonic kidney; PDS; 4,4â²-dip
Aldosterone as a renal growth factor
Keywords: پروتئین کیناز D; Aldosterone; Kidney; Protein kinase D; EGFR; Polycystic kidney disease; Mitogen activated protein kinase
High affinity receptor for IgE stimulation activates protein kinase D augmenting activator protein-1 activity for cytokine producing in mast cells
Keywords: پروتئین کیناز D; Mast cell; Protein kinase D; AP-1; IL-13; TNF-α; FcεRI
Atorvastatin reverses cardiac remodeling possibly through regulation of Protein Kinase D/Myocyte Enhancer Factor 2D activation in spontaneously hypertensive rats
Keywords: پروتئین کیناز D; Atorvastatin; Protein Kinase D; Myocyte Enhancer Factor 2D; Cardiac remodeling
Protein kinase D activation stimulates the transcription of the insulin receptor gene
Keywords: پروتئین کیناز D; Insulin receptor; Gene expression; Protein kinase D; Berberine
Protein kinase D1 and D2 are involved in chemokine release induced by toll-like receptors 2, 4, and 5
Keywords: پروتئین کیناز D; Protein kinase D; Innate immunity; Toll-like receptors; Chemokines
Rescue of familial cardiomyopathies by modifications at the level of sarcomere and Ca2+ fluxes
Keywords: پروتئین کیناز D; SR; sarcoplasmic reticulum; RyR; ryanodine receptor; SERCA; sarcoplasmic reticulum Ca2+ ATPase; ATP; adenosine triphosphate; PLB; phospholamban; HCM; hypertrophic cardiomyopathy; FHC; familial hypertrophic cardiomyopathy; DCM; dilated cardiomyopathy; MYH7
Protein kinase D1 modulates aldosterone-induced ENaC activity in a renal cortical collecting duct cell line
Keywords: پروتئین کیناز D; Aldosterone; ENaC; Protein kinase D; Renal; Cortical collecting duct; Hypertension