دانلود مقالات ISI درباره سیلک + ترجمه فارسی

Quantitative proteomic profiling reveals hepatic lipogenesis and liver X receptor activation in the PANDER transgenic model

Keywords: سیلک; Fam3B; PANDER; Liver; Lipogenesis; Fatty acid synthesis; Liver X receptor; SILAC; Proteomics;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Yeast membrane proteomics using leucine metabolic labelling: Bioinformatic data processing and exemplary application to the ER-intramembrane protease Ypf1

Keywords: سیلک; d3-leucine; trideuterated leucine; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum associated degradation; LC-MS; liquid chromatography-mass spectrometry; PSM; peptide-to-spectrum matches; SILAC; stable isotope labelling by amino acids in cell cu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Triple SILAC quantitative proteomic analysis reveals differential abundance of cell signaling proteins between normal and lung cancer-derived exosomes

Keywords: سیلک; Exosomes; Non-small cell lung cancer; SILAC; Quantitative proteomics;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential

Keywords: سیلک; ATG; autophagy-related gene; AMPK; AMP activated protein kinase; BECN1; beclin1; b-TrCP; beta-transducin repeat-containing protein; Cbl; Casitas B-lineage lymphoma; CHIP; Carboxyl terminus of Hsc70 interacting protein; CHMP2B; charged multivesicular body

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

A role for mRNA trafficking and localized translation in peroxisome biogenesis and function?

Keywords: سیلک; ChIP; chromatin immunoprecipitation; CLIP; crosslinking immunoprecipitation; ER; endoplasmic reticulum; FISH; fluorescent in situ hybridization; GET; Golgi-ER trafficking; ISH; in situ hybridization; MFP; multifunctional protein; mPP; mRNA encoding peroxi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Classification-based quantitative analysis of stable isotope labeling by amino acids in cell culture (SILAC) data

Keywords: سیلک; Classification; Mass spectrometry; Particle swarm optimization; Proteomics; SILAC;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Peroxiredoxin-2 nitrosylation facilitates cardiomyogenesis of mouse embryonic stem cells via XBP-1s/PI3K pathway

Keywords: سیلک; ES cell; embryonic stem cell; EB; embryoid body; DHE; Dihydroethidium; DHR; Dihydrorhodamine 123; DTT; Dithiothreitol; GO; Gene Ontology; GSNO; S-nitrosoglutathione; H2O2; hydrogen peroxide; NO; nitric oxide; ODQ; 1H-[1,2,4]oxadiazolo[4,3a]quinoxalin-1-on

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC)

Keywords: سیلک; Secretome; Silac; Endothelial cells; Ischemic stroke; Biomarkers; Cerebral ischemia; Blood-brain-barrier;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of pathways related to FAF1/H. pylori-associated gastric carcinogenesis through an integrated approach based on iTRAQ quantification and literature review

Keywords: سیلک; FAF1; Fas-associated factor 1; FA; formic acid; IAA; iodoacetamide; TEAB; triethylammonium bicarbonate; RPMI-1640; Roswell Park Memorial Institute-1640; PPA; protein pathway array; SILAC; stable isotope labeling with amino acids in cell culture; ATP; aden

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

BONLAC: A combinatorial proteomic technique to measure stimulus-induced translational profiles in brain slices

Keywords: سیلک; BONLAC; BONCAT; SILAC; de novo proteomics; BDNF; hippocampal slice; synaptic plasticity; protein synthesis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics

Keywords: سیلک; CDK8-Mediator; Mediator; SILAC; cholesterol; MED13; MED13L; SIRT1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Phosphoproteomic Analyses of NRAS(G12) and NRAS(Q61) Mutant Melanocytes Reveal Increased CK2α Kinase Levels in NRAS(Q61) Mutant Cells

Keywords: سیلک; a-loop; activation loop; ERK; extracellular signal-regulated kinase; GO; gene ontology; GTP; guanosine triphosphate; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinase; NRAS; neuroblastoma rat sarcoma viral homolog; PHM; primary human melanocyte

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Changes in lipid raft proteome upon TNF-α stimulation of cystic fibrosis cells

Keywords: سیلک; Cystic fibrosis; CFTR; Lipid rafts; GPCR; SILAC; Inflammation;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics

Keywords: سیلک; AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; AKAP; A-kinase anchor protein; AMP; 5′ adenosine monophosphate; AMPK; AMP-activated protein kinase; Arfgap1; ADP-ribosylation factor GTPase-activating protein 1; Arhgef2; Rho guanine nucleotide ex

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy

Keywords: سیلک; MNK; MAP kinase-interacting kinase; TMZ; temozolomide; GBM; glioblastoma; MTC; medullary thyroid carcinoma; ERK; extracellular signal-regulated kinases; eIF4E/G1; eukaryotic translation initiation factor 4E/G1; MAPK; mitogen-activated protein kinase; GAPD

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Quantitative proteomics in Giardia duodenalis—Achievements and challenges

Keywords: سیلک; 2-DE; two-dimensional gel electrophoresis; ADI; arginine deiminase; AUC; area under the curve; CW; cyst wall; CWP; cyst wall protein; DDA; data-dependent acquisition; DIA; data-independent acquisition; ERIF; environmentally resistant infective form; ESV;

دانلود رایگان متن کامل مقاله ISI 66 صفحه سال انتشار : 2016 سفارش ترجمه

Ablation of Dicer leads to widespread perturbation of signaling pathways

Keywords: سیلک; Dicer; Phosphotyrosine; Pathways; Receptor tyrosine kinase; SILAC;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Proteomics applications in Caenorhabditis elegans research

Keywords: سیلک; Caenorhabditis elegans; Peptidomics; Proteomics; Systems biology; Biological applications; PD; Parkinson's disease; SILAC; Stable isotope labeling with amino acids in cell culture; iTRAQ; Isobaric tag for relative and absolute quantitation; ICAT; Isotope

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

SILAC-based quantification of changes in protein tyrosine phosphorylation induced by Interleukin-2 (IL-2) and IL-15 in T-lymphocytes

Keywords: سیلک; SILAC; Interleukin; Cell signaling; Phosphotyrosine; T-lymphocytes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Off-target responses in the HeLa proteome subsequent to transient plasmid-mediated transfection

Keywords: سیلک; SILAC; Transient transfection; Off-target effects; Antiviral response; Interferon response; HeLa;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1

Keywords: سیلک; DNA repair proteins; Quantitative proteomics; SILAC; Phosphorylation; EGFR inhibition; PARP1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Proteomic profile of aminoglutethimide-induced apoptosis in HL-60 cells: Role of myeloperoxidase and arylamine free radicals

Keywords: سیلک; Aminoglutethimide; HL-60 cells; SILAC; Apoptosis; Free radical metabolites; Drug-induced toxicity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Modulation of TCR responsiveness by the Grb2-family adaptor, Gads

Keywords: سیلک; DAG; diacylglycerolDSB, double strand break; Gads; Grb2-related adaptor downstream of Shc; Indel; insertion and deletion mutation; GFP; green fluorescent protein; Grap; Grb2-related adaptor protein; Grb2; growth factor receptor-bound 2; IRES; internal rib

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Stable isotope labeling by amino acids in cell culture based proteomics reveals differences in protein abundances between spiral and coccoid forms of the gastric pathogen Helicobacter pylori

Keywords: سیلک; Helicobacter pylori; SILAC; Cell morphology; Quantitative proteomics

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Targeted mass spectrometry for the analysis of nutritive modulation of catalase and heme oxygenase-1 expression

Keywords: سیلک; Selected reaction monitoring; SILAC; Targeted mass spectrometry; Expression analysis; Food proteomics; Nutrition

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells

Keywords: سیلک; DTT; dithiothreitol; EGTA; ethylene glycol tetraacetic acid; FACS; fluorescence-activated cell sorting; HA; human influenza hemagglutinin; HCD; higher-energy collisional dissociation; HPLC; high performance liquid chromatography; PCNA; proliferating cellu

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

SILAC-based comparative analysis of pathogenic Escherichia coli secretomes

Keywords: سیلک; Escherichia coli pathogenesis; OMV; Secretome; SILAC; Virulence factors;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

A cleavable cytolysin-neuropeptide Y bioconjugate enables specific drug delivery and demonstrates intracellular mode of action

Keywords: سیلک; Peptide-drug conjugate; Neuropeptide Y; Cytolysin; Breast cancer; SILAC; Quantitative proteomics;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells

Keywords: سیلک; UPRmt (mitochondrial unfolded protein response); ClpXP; Proteomics; SILAC; Myogenesis; CHOP/Ddit3/CEBPZ/GADD153;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Development of tag-free photoprobes for studies aimed at identifying the target of novel Group A Streptococcus antivirulence agents

Keywords: سیلک; SK; streptokinase; GAS; Group A Streptococcus; HTS; high-throughput screen; SAR; structure-activity relationship; TPSA; topological polar surface area; c Log P; logarithm of the calculated octanol-water partition coefficient; LDA; lithium diisopropy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Quantitative proteomics reveals the link between minichromosome maintenance complex and glucose-induced proliferation of rat pancreatic INS-1E β-cells

Keywords: سیلک; MCM; mini chromosome maintenance; SILAC; stable isotope labeling with amino acids in cell culture; T2D; type 2 diabetes; β-Cell; Proliferation; Nuclei; MiniChromosome maintenance complex;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of PPAR-alpha pathway by Dicer revealed through proteomic analysis

Keywords: سیلک; PPAR; Peroxisome Proliferator-Activated Receptor; SILAC; stable isotope labeling by amino acids in cell culture; BRPLC; basic reversed phase liquid chromatography; FDR; false discovery rate; MRM; multiple reaction monitoring; Pbe; peroxisomal bifunctional

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Quantitative phosphoproteomics reveals novel phosphorylation events in insulin signaling regulated by protein phosphatase 1 regulatory subunit 12A

Keywords: سیلک; Quantitative phosphoproteomics; Serine/threonine protein phosphatase 1 regulatory subunit 12A (PPP1R12A); Insulin signaling; Protein phosphatase 1 (PP1); Skeletal muscle; SILAC;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Quantitative proteomics reveals ER-α involvement in CD146-induced epithelial-mesenchymal transition in breast cancer cells

Keywords: سیلک; SILAC; Stable Isotope Labeling with Amino Acids in Cell Culture; EMT; epithelial-mesenchymal transition; TNBC; ER−/PR−/ERBB− triple-negative breast cancer; ER; estrogen receptor; ER-α; estrogen receptor-α; ER-β; estrogen receptor-β; RT-PCR; re

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin

Keywords: سیلک; Colorectal cancer; Cancer-associated fibroblasts; Migration; Claudin-11; SILAC; CAF; cancer-associated fibroblast; CALD; caldesmon; CLN11; claudin 11; CM; conditioned media; ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transition; ICC; immuno

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of EGFR and ERBB2 by Helicobacter pylori Results in Survival of Gastric Epithelial Cells With DNA Damage

Keywords: سیلک; Marker; Prognostic Factor; Risk; Signal Transduction Pathways; EGFR; epidermal growth factor receptor; ERBB; erythroblastic leukemia-associated viral oncogene B; GC; gastric cancer; IM; intestinal metaplasia; ImSt; immortalized stomach; mRNA; messenger RN

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2014 سفارش ترجمه

Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL

Keywords: سیلک; ESDN; endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; discoidin CUB and LCCL domain containing 2; CUB; complement C1r/C1s Uegf Bmp1; CrkL; CrkCT10 regulator of kinase Crk-Like; SFK; Src family tyrosine kinase; Cas; Crk-associat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions. A method to directly monitor the active conformation of LRRK2?

Keywords: سیلک; IP; immunoprecipitates; LRRK2; leucine-rich repeat kinase 2; PD; Parkinson's disease; Roc; Ras of complex protein; SILAC; stable isotope labeling of amino acids in culture; LRRK2; Kinase domain; Activation segment; Conformation; Antibody; Immunoprecipitat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Solid-phase capture for the detection and relative quantification of S-nitrosoproteins by mass spectrometry

Keywords: سیلک; CysNO; S-nitrosocysteine; GSNO; S-nitrosoglutathione; iTRAQ; isobaric tags for relative and absolute quantitation; LC-MS/MS; liquid chromatography tandem mass spectrometry; SILAC; stable isotope labeling of amino acids in culture; SNO; S-nitrosothiol; SNO

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The proteome of Toll-like receptor 3-stimulated human immortalized fibroblasts: Implications for susceptibility to herpes simplex virus encephalitis

Keywords: سیلک; Herpes simplex virus encephalitis (HSE); SILAC; proteomics; mass spectrometry; fibroblast; herpes simplex virus 1 (HSV-1); TLR3; IFN; CNS; Central nervous system; H; Heavy medium; HSE; Herpes simplex virus encephalitis; HSV-1; Herpes simplex virus 1; 1ICA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Review of software tools for design and analysis of large scale MRM proteomic datasets

Keywords: سیلک; CV; coefficient of variation; ELISA; enzyme-linked immunosorbent assay; FDR; false discovery rate; FWHM; full width of peak at half max peak height; iTRAQ; isobaric tag for relative and absolute quantitation; LC-MS/MS; liquid chromatography MS/MS; MRM;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Cleaning up the masses: Exclusion lists to reduce contamination with HPLC-MS/MS

Keywords: سیلک; HPLC-MS/MS; high pressure liquid chromatography-tandem mass spectrometry; ACN; acetonitrile; PEG; polyethylene glycol; BSA; bovine serum albumin; PTM; post translation modification; MS; mass spectrometry; MRM; multiple reaction monitoring; SRM; selective

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Protein tyrosine phosphatase SHP2/PTPN11 mistargeting as a consequence of SH2-domain point mutations associated with Noonan Syndrome and leukemia

Keywords: سیلک; dFCS; dialyzed fetal calf serum; GO; Gene Ontology; IPI; International Protein Index; LTQ; linear trap quadrupole; SILAC; stable isotope labeling by amino acids in cell culture; Arg6; l-arginine-13C6,14N4; Arg10; l-arginine-13C6,15N4; Lys4; l-lysine-2H4;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Quantitative secretome analysis reveals the interactions between epithelia and tumor cells by in vitro modulating colon cancer microenvironment

Keywords: سیلک; ACN; acetonitrile; CM; conditioned medium; CRC; colorectal cancer; 13C6-Lys; 13C6-lysine; EMT; epithelial mesenchymal transition; ESI-TOF; electrospray ionization-time-of-flight; FBS; fetal bovine serum; IGF; insulin-like growth factor; IGFBP6; insulin-li

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2013 سفارش ترجمه

Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation

Keywords: سیلک; ACN; acetonitrile; AGC; automatic gain control; CID; collision induced dissociation; CREB; 3′-5′-cyclic adenosine monophosphate response element-binding protein; CRTC2; CREB regulated transcription coactivator 2; DTT; dithiothreitol; FA; formic acid;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2013 سفارش ترجمه

Functional proteomics approaches for the identification of transnitrosylase and denitrosylase targets

Keywords: سیلک; 2DE; Two-dimensional gel electrophoresis; ACN; Acetonitrile; BB; Binding buffer; BCA; Bicinchoninic acid; Biotin-HPDP; N-[6-(Biotinamido)hexyl]-3′-(2′-pyridyldithio)-propionamide; BST; Biotin-switch technique; CID; Collision-induced dissociation; DDA;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2013 سفارش ترجمه

Quantitative profiling of tyrosine phosphorylation revealed changes in the activity of the T cell receptor signaling pathway upon cisplatin-induced apoptosis

Keywords: سیلک; 7-AAD; 7-amino-actinomycin D; Atf2; activating transcription factor 2; Csk; C-terminal Src kinase; Erk; extracellular-signal-regulated kinase; FCB; fluorescent cell barcoding; FSC; forward scatter; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IL-2; in

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2013 سفارش ترجمه

From quantitative protein complex analysis to disease mechanism

Keywords: سیلک; Cilium; Intraflagellar transport; Ciliopathy; Affinity purification; Protein complex analysis; SF-TAP; SILAC; Mass spectrometry; Disease mechanism; Leber’s congenital amaurosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

MilQuant: A free, generic software tool for isobaric tagging-based quantitation

Keywords: سیلک; ETD; Electron transfer dissociation; HCD; High energy collision dissociation; IT; Ion trap; iTRAQ; Isobaric tags for relative and absolute quantitation; MS; Mass spectrometry; PQD; Pulsed Q dissociation; PSM; Peptide-spectrum match; SILAC; Stable isotope

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Mass spectrometric analysis identifies a cortactin–RCC2/TD60 interaction in mitotic cells

Keywords: سیلک; SILAC; Focal adhesion; Cortactin; RCC2/TD60

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه