Cleavage of the interchain disulfide bonds in rituximab increases its affinity for FcγRIIIA
Keywords: الکتروفورز ژل دوده سولفات سدیم پلی آکریل آمید; RTX; rituximab; S-RTX; S-sulfonated rituximab; A-RTX; reduced and then alkylated rituximab; mAb; monoclonal antibody; ADCC; antibody-dependent cellular cytotoxicity; FcγR; Fcγ receptor; KHYG-1/FcγRIIIA; KHYG-1 cells stably expressing FcγRIIIA; SDS-P