Piezoresistive and electrical properties of Cr containing diamond-like carbon films
Keywords: Cr containing diamond like carbon; Piezoresistance; TCR; Raman; XPS;
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Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolonged STAT activation through autocrine/paracrine stimulation in human primary T cells
Keywords: TCR; T-cell antigen receptor; MHC; major histocompatibility complex; ZAP-70; zeta-associated protein kinase of 70Â kD; IL; interleukin; JAK; Janus kinase; SOCS; suppressor of cytokine signaling; CIS; cytokine-inducible SH2-containing protein; NFAT; nuclea
Large Granular Lymphocytic Leukemia: A Treatable Form of Refractory Celiac Disease
Keywords: T-Cell Receptor; Immune Regulation; Lymphocyte Proliferation; Villous Atrophy; CD; celiac disease; IEL; intraepithelial lymphocytes; LGL; large granular leukemia; LPL; lamina propria lymphocyte; PBL; peripheral blood lymphocyte; RCD; refractory celiac dis
Interesting possibilities to improve the safety and efficacy of ipilimumab (Yervoy)
Keywords: Breakdown; Efficacy; Improve; Ipilimumab; Tolerance; Safety; Yervoy; allo-HSCT; allogeneic hematopoietic stem cell transplantation; APC; antigen-presenting cell; CLL; chronic lymphocytic leukemia; CTLA-4; cytotoxic T lymphocyte-associated antigen-4; gp100
Cellular calibrators to quantitate T-cell receptor excision circles (TRECs) in clinical samples
Keywords: TREC; Tâcell receptor excision circle; TCR; Tâcell receptor; DBS; dried blood spots; SCID; Severe combined immunodeficiency; HCT; hematopoietic cell transplantation; EBV; Epstein Barr virus; TREC-EBV; Tâcell receptor excision circle-Epstein Barr v
Ultra-sensitive detection of rare T cell clones
Keywords: TCR; Repertoire; MRD;
PCR for monitoring of minimal residual disease in hematologic malignancy
Keywords: MRD; minimal residual disease; HSCT; hematopoietic stem cell transplantation; MFC; multiparameter flow cytometry; qPCR; quantitative polymerase chain reaction; Ig; immunoglobulin; TCR; T-cell receptor; STR-PCR; short tandem repeat-PCR; AML; acute myelogen
Research ArticleNaïve CD8 T cell activation by liver bone marrow-derived cells leads to a “neglected” IL-2low Bimhigh phenotype, poor CTL function and cell death
Keywords: IL-2R; interleukin-2 receptor; bm; bone marrow; IL-2; interleukin-2; KC; Kupffer cells; LSEC; liver sinusoidal endothelial cells; DC; dendritic cells; APC; antigen presenting cells; ICAM-1; intercellular adhesion molecule-1; LN; lymph node; TCR; T cell re
Research ArticleTwo lymph nodes draining the mouse liver are the preferential site of DC migration and T cell activation
Keywords: B6; C57BL/6; DC; dendritic cell; LN; lymph node; MHC; major histocompatibility complex; TCR; T cell receptor; Gb; gallbladder; IVC; inferior vena cava; PV; portal vein; Liver; T cells; Draining lymph nodes; Dendritic cells; Transgenic mice;
Thymic functions and gene expression profile distinct double-negative cells from single positive cells in the autoimmune lymphoproliferative syndrome
Keywords: ALPS; Autoimmune lympho-proliferative syndrome; DN; Double-negative; tDN; Thymic double-negative; PBMCs; peripheral blood mononuclear cells; SP; Single-positive; TCR; T-cell receptor; TRECs; T-cell receptor excision circles; Ct; Cycle threshold; qRT-PCR;
Functional capability of IL-15-Akt signaling in the denervated muscle
Keywords: IL-1β; interleukin-1β; IL-1a; IL-1β receptor antagonist; IL-15; interleukin-15; CD48; LFA-3, cluster of differentiation 48; CD2; cluster of differentiation 2; APC; antigen present cell; TCR; T cell receptor; MTT; 3-(4,5-cimethylthiazol-2-yl)-2,5-diphen
Autophagy and the regulation of the immune response
Keywords: Atg; autophagy related protein; DC; dendritic cells; Hsc70; heat shock cognate protein of 70Â kD; LAMP-2A; lysosome-associated membrane protein type 2A; LC3; light chain 3 protein; MHC; major histocompatibility complex; NLR; Nod-like receptor; TCR; T cell
Development of unique antibodies directed against each of the six different phosphotyrosine residues within the T cell receptor CD3ζ chain
Keywords: ITAM; immunoreceptor tyrosine-based activation motif; TCR; T cell antigen receptor; CD3ζ; the zeta chain of the TCR/CD3 complex; pTyr-CD3ζ; tyrosine phosphorylated CD3ζ; IB; immunoblot; IP; immunoprecipitation; CD3ζ chain; Tyrosine phosphorylation; Ph
Origin and immunophenotype of aberrant IEL in RCDII patients
Keywords: APC; allophycocyanin; CD; coeliac disease; EATL; enteropathy associated T-cell lymphoma; EMA-A; endomysial IgA antibodies; FACS; fluorescence activated cell sorter; FITC; fluorescein isothiocyanate; GFD; gluten free diet; IEL; intraepithelial lymphocyte;
The inositol 5-phosphatase SHIP-1 and adaptors Dok-1 and 2 play central roles in CD4-mediated inhibitory signaling
Keywords: SHIP-1, SH2 domain-containing inositol 5 phosphatase; Dok, Downstream of kinaseCD4; SHIP-1; Dok-1/2; TCR; HIV-1
NEMO differentially regulates TCR and TNF-α induced NF-κB pathways and has an inhibitory role in TCR-induced NF-κB activation
Keywords: NEMO; NF-κB essential modulator; siRNA; small interfering RNA; TCR; T cell receptor; CBM; CARMA1-Bcl10-MALT1 complex; IS; Immunological synapse; shRNA; short hairpin RNA; SM; Soluble membrane; DI; Detergent Insoluble cytoskeleton fraction; AICD; activati
T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses
Keywords: NOD, nonobese diabetic; T1D, Type 1 diabetes; PLN, pancreatic lymph nodes; CDR3, complementary determining region 3; CYP, cyclophosphamide; Tregs, regulatory T cells; ANOVA, analysis of varianceAutoimmune disease; TCR; CDR3; Diabetes; Pancreatic lymph nod
Applications of Next-Generation Sequencing to Blood and Marrow Transplantation
Keywords: Genome analysis; Exome sequencing; Transplantation; TCR
Diacylglycerol kinase ζ: At the crossroads of lipid signaling and protein complex organization
Keywords: APC; antigen-presenting cell; DAG; diacylglycerol; DGK; diacylglycerol kinase; GFP; green fluorescent protein; GPCR; G protein-coupled receptor; LTP; long-term potentiation; MARCKS; myristoylated alanine-rich C kinase substrate protein; PDZ-bm; PDZ bindin
SDS3 interacts with ARNT in an AhR ligand-specific manner regulating expression of cKrox and S100A4 in CD4+CD8+ DPK thymocytes differentiation
Keywords: DN; double negative; DP; double positive; SP; single positive; TCR; T cell receptor; MAPK; MAP kinase; ERK; extracellular signal regulated protein kinase; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDD; Benzo(a)pyrene; SDS3; CD4+CD8+; AhR; ARNT;
Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks
Keywords: Abl; Abelson tyrosine-protein kinase 1; ADAP1; arf-GAP with dual PH domain-containing protein 1; AFM; atomic force microscopy; cAMP; cyclic adenosine monophosphate; ApoER2; apolipoprotein E receptor 2; BCAR1; breast cancer anti-estrogen resistance 1; p130
Dysregulation of CD1d-Restricted Type II Natural Killer T Cells Leads to Spontaneous Development of Colitis in Mice
Keywords: IBD; Crohn's Disease; Immune Regulation; T-Cell Development; α-GalCer; α-galactosylceramide; DSS; dextran sulfate sodium; HBSS; Hank's balanced salt solution; IFN; interferon; IL; interleukin; NK; natural killer; TCR; T-cell receptor;
Life in the serendipitous lane: Excitement and gratification in studying DNA repair
Keywords: AP; apurinic/apyrimidinic; BER; base excision repair; DECAF; DDB-1-Cul4-Associated Factor; DMBA; 7,12 dimethylbenz[α]anthracene; GGR; global genomic repair; HAT; histone acetyltransferase; HCR; host cell reactivation; hLig; human DNA ligase; MMNG; N-meth
Rearrangement patterns of the canine TCRγ locus in a distinct group of T cell lymphomas
Keywords: D; diversity; EMBL; European Molecular Biology Laboratory; J; joining; PCR; polymerase chain reaction; RAG; recombination-activating gene; RSS; recombination signal sequence; TCR; T cell receptor; TRG; T cell receptor gamma; V; variable; Dog; Gamma delta
The Membrane-Bound Mucin Muc1 Regulates T Helper 17-Cell Responses and Colitis in Mice
Keywords: Susceptibility; Risk Factor; Mouse Model; Immune Regulation; CD; Crohn's disease; DC; dendritic cells; DKO; double knockout; FACS; fluorescence-activated cell sorter; GWAS; genome-wide association studies; HRP; horseradish peroxidase; IBD; inflammatory bo
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome
Keywords: Carbamazepine; drug hypersensitivity; HLA; Stevens-Johnson syndrome; toxic epidermal necrolysis; AED; Antiepileptic drug; APC; Antigen-presenting cell; B-LCL; EBV-transformed B-cell line; CBZ; Carbamazepine; CTL; Cytotoxic T lymphocyte; ECBZ; Carbamazepin
Increased Levels of Arginase in Patients With Acute Hepatitis B Suppress Antiviral T Cells
Keywords: Immune Regulation; Liver Disease; Virology; Treatment; AHB; acute hepatitis B; CMV; cytomegalovirus; EBV; Epstein-Barr virus; GFP; green fluorescent protein; HCMV; human cytomegalovirus; ICS; intracellular cytokine staining; IFN; interferon; IL; interle
Binding of Hepatitis A Virus to Its Cellular Receptor 1 Inhibits T-Regulatory Cell Functions in Humans
Keywords: Hepatitis A Virus Cellular Receptor 1; Viral Clearance; TGF-β, Immune Regulation; AP-1; activator protein 1; FoxP3; forkhead box protein 3; HAV; hepatitis A virus; HAVCR1; hepatitis A virus cellular receptor 1; IgV; immunoglobulin V-like domain; HEK; hum
IL-33 induces innate lymphoid cell-mediated airway inflammation by activating mammalian target of rapamycin
Keywords: IL-33; TH2; innate lymphoid cells; asthma; mammalian target of rapamycin; rapamycin; AHR; Airway hyperresponsiveness; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; Lin; Lineage-specific marker;
The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells
Keywords: CSB; Cockayne syndrome group B protein; fusion protein; short for CSB-PGBD3 fusion protein and used interchangeably; HCR; host cell reactivation; IFN; interferon; IGFBP5 and IGFBP7; insulin growth factor binding proteins 5 and 7; My; million years; Mya; m
T Cells That Target Carcinoembryonic Antigen Eradicate Orthotopic Pancreatic Carcinomas Without Inducing Autoimmune Colitis in Mice
Keywords: Chimeric Antigen Receptor; Adoptive Cell Therapy; CEA; Immune Cell Therapy; CAR; chimeric antigen receptor; CBLuc; click beetle luciferase; CEA; carcinoembryonic antigen; GLuc; Gaussia luciferase; IL; interleukin; mAb; monoclonal antibody; MPO; myeloperox
REVIEWImmunodominance: A pivotal principle in host response to viral infections
Keywords: ImDc; immunodominance; ImD; immunodominant; SbD; Subdominant; Flu; Influenza A; HIV; Human immunodeficiency virus; Tg; transgenic; TCR; T cell receptor; pMHC; peptide/MHC class I complex; CTL; cytotoxic T lymphocyte; APCs; Antigen presenting cells; HLA; H
Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency
Keywords: CD4; lymphopenia; autoinflammation; recurrent infections; LCK, SRC tyrosine kinase; genetic defect; immunodeficiency; T-cell receptor signaling; CDR3; Complementary-determining region 3; CD62L; CD62 ligand; CID; Combined immunodeficiency; ERK; Extracellul
CCL2-Induced Migration and SOCS3-Mediated Activation of Macrophages Are Involved in Cerulein-Induced Pancreatitis in Mice
Keywords: Immune Response; Signaling; Mouse Model; Chemokine; APC; antigen-presenting cell; BM; bone marrow; cDC; classical dendritic cells; cKO; conditional knockout; IL; interleukin; L-Arg; L-arginine; LPS; lipopolysaccharide; MDSC; myeloid-derived suppressor cel
Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo
Keywords: Cigarette smoke; nicotine; nicotinic acetylcholine receptors; γ-aminobutyric acid receptors; acetylcholine; airway mucus; AB/PAS; Alcian blue/periodic acid-Schiff; ALI; Air-liquid interface; GABAAR; γ-Aminobutyric acid type A receptor; GAPDH; Glycera
Highly sensitive GaAs/AlGaAs heterojunction bolometer
Keywords: 07.57Kp; 95.55 Rg; 85.25Pb; 85.60GzGaAs/AlGaAs; TCR; Bolometer; Room temperature
Intracellular bacteria can cause EAE in SJL mice or modify self-specific T cell repertoire
Keywords: EAE; PLP; TCR; Mycobacterium; TLR; T cell recirculation;
Real time detection of peptide-MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability
Keywords: pMHC; peptide-major histocompatibility complex; MFI; mean fluorescence intensity; FACS; fluorescent activated cell sorting; SPR; surface plasmon resonance; TCR; T-cell receptor; Surface plasmon resonance (SPR); Peptide-major histocompatibility complex
Intracellular free zinc up-regulates IFN-γ and T-bet essential for Th1 differentiation in Con-A stimulated HUT-78 cells
Keywords: IFN-γ; interferon-γ; IL-12Rβ2; IL-12 receptor β2; PKC; protein kinase C; Con-A; concanavalin-A; TCR; T-cell receptor; PMA; phorbol-12 myristate-13-acetate; PHA; phytohemagglutinin-p; Zinc; T-bet; IFN-γ; IL-12Rβ2;
Detection of T-cell receptor gene rearrangement in children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis using the BIOMED-2 multiplex polymerase chain reaction combined with GeneScan analysis
Keywords: BIOMED-2 multiplex PCR; EBV; HLH; TCR; T-cell clonality;
Maternal origin of a de novo microdeletion spanning the ERCC6 gene in a classic form of the Cockayne syndrome
Keywords: Cockayne syndrome; ERCC6 gene; Mutation; Microdeletion; CS; Cockayne syndrome; NER; Nucleotide excision repair; TCR; Transcription-coupled DNA repair; SNP; Single nucleotide polymorphism; PAH; Phenylalanine hydroxylase;
Absence of TCR loci chromosomal translocations in cutaneous T-cell lymphomas
Keywords: Cutaneous T-cell lymphomas; fluorescence in situ hybridization; TCR
SiGe/Si quantum structures as a thermistor material for low cost IR microbolometer focal plane arrays
Keywords: TCR; Noise; NETD; Bolometer; Thermistor; Quantum wells; Semiconductor; Infrared
PD-L2 is expressed on activated human T cells and regulates their function
Keywords: PD-1; programmed death 1; PD-L; programmed death 1 ligand; APCs; antigen presenting cells; TcR; T cell receptor; mAb; monoclonal antibody; T cells; Cell activation; Costimulatory molecules; PD-L2;
Creatine does not promote hypertrophy in skeletal muscle in supplemented compared with nonsupplemented rats subjected to a similar workload
Keywords: BW; body weight; CO; nontrained without Cr supplementation; Cr; creatine; CR; nontrained with Cr supplementation; CSA; cross-sectional area; MW; muscle weight; TCr; total Cr; TR; trained without Cr supplementation; TRCR; trained with Cr supplementation; S
Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function
Keywords: PI3Kδ; phosphoinositide 3-kinase delta; PIP3; phosphoinositide 3,4,5-triphosphates; SH2; Src homology-2; PH; pleckstrin homology; KD; kinase-dead; KO; knockout; BCR; B cell receptor; GPCR; G protein-coupled receptor; TCR; T cell receptor; FcεRI; high af
Natural History of Potential Celiac Disease in Children
Keywords: Anti-TG2 IgA Intestinal Deposits; Gluten Sensitive Enteropathy; Gluten Free Diet; Anti-TG2 Antibodies; Ad-SoS; amplitude-dependent speed of sound; anti-TG2; antitissue transglutaminase 2; CD; celiac disease; EMA; anti-endomysial antibodies; GFD; gluten-fr
Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Keywords: CTL; cytotoxic T lymphocyte; HIV; human immunodeficiency virus; HLA; human leukocyte antigen; RMSD; root mean square deviation; TCR; T cell receptor; HLA-A*0301; HLA-A*1101; HLA-A3 supertype; Crystal structure; Cross-presentation; T cell epitopes; IMGT;
Effects of Cr buffer layer thickness on the microstructure and the properties of Ni thin films deposited on polyimide substrate
Keywords: Cr buffer layer; Thickness; Microstructure; Resistivity; TCR;
JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation
Keywords: Treg, regulatory T cells; TCR, T cell receptor; TGF-β, transforming growth factor; IL-2, interleukin-2; ChIP, chromatin immunoprecipitationFoxp3; Transcription; TCR; TGF-β; IL-2; Epigenetics; JunB; c-Rel