دانلود مقالات ISI درباره سیستم ubiquitin-proteasome + ترجمه فارسی

تعبیر خواب: دوست و دشمن در سرطان

Ubiquitination: Friend and foe in cancer

Keywords: سیستم ubiquitin-proteasome; Ub; ubiquitin; UBLs; ubiquitin-like proteins; DUBs; deubiquitinating enzymes; TCR; T cell receptor; UPS; ubiquitin-proteasome system; IAPs; inhibitors of apoptosis-related proteins; GAPs; GTPase-activating proteins; PI3K; phosphatidylinositol 3-kinase;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

تجمع پروتئین و تولید نوروژنز در بیماریهای نورولوژیکی پیشآهنگی: نمونه هایی از آمیلوئیدوپاتی، تئوپاتی ها و سینوژین پپتیدها

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

Keywords: سیستم ubiquitin-proteasome; Aβ; beta-amyloid peptide; AAV; adeno-associated virus; ABAD; amyloid-beta-binding alcohol dehydrogenase; AD; Alzheimer's disease; ALP; autophagy-lysosome pathways; Apaf-1; apoptic protease-activating factor 1; APP; amyloid precursor protein; AICD; APP in

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

صفحه نمایش گسترده ی ژنوم، ماشین های جدیدی را که برای هر دو سیلوژنز و چرخه ی سلولی بر روی گرسنگی سرم نیاز دارند، شناسایی می کند.

Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation

Keywords: سیستم ubiquitin-proteasome; High-content screen; Ciliogenesis; Cell cycle; mRNA processing; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

اثر سیس پلاتین بر فعالیت پروتئازم

Effect of cisplatin on proteasome activity

Keywords: سیستم ubiquitin-proteasome; UPS; ubiquitin-proteasome system; ER; endoplasmic reticulum; PMSF; phenylmethylsulfonyl fluoride; DTT; di-thio-threitol; EDTA; ethylene-diamino-tetra-acetic; CP; core particle of proteasome; RP; regulatory particle of proteasome; Cisplatin; Proteasome;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

گیرنده سیگما-1 در تخریب اتم های میان هسته ای در یک مدل سلولی از بیماری هانتینگتون دخیل است

Sigma-1 receptor is involved in degradation of intranuclear inclusions in a cellular model of Huntington's disease

Keywords: سیستم ubiquitin-proteasome; Sigma-1 receptor; Huntington's disease; Neuronal nuclear inclusions; Ubiquitin-proteasome system; Endoplasmic reticulum chaperone; Endoplasmic reticulum-associated degradation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

فعال سازی پروتئازوم: رویکرد نوآورانه برای تأخیر در ایجاد بیماری های مرتبط با پیری و عقب ماندگی

Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases

Keywords: سیستم ubiquitin-proteasome; Ubiquitin-proteasome system; Proteasome activation; Aging; Senescence; Longevity; Age-related diseases;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

تعاملات مجتمع دامنه ثبات و فعالیت فاکتورهای رونویسی پیشانی نزدیک را تنظیم می کند

Complex domain interactions regulate stability and activity of closely related proneural transcription factors

Keywords: سیستم ubiquitin-proteasome; bHLH; basic Helix-Loop-Helix; Ngn2; Neurogenin 2; UPS; Ubiquitin-Proteasome System; Ub; ubiquitin; ANOVA; analysis of variance; UD; unfolded domain; Xenopus; Ubiquitylation; Neurogenesis; Proneural; Proteasomal degradation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

تغییرات پروتئین ناشی از کوئینون: پیامدهای سیستمهای اصلی انتقال پروتئین در مسمومیت با هیدروکسید کینون

Quinone-induced protein handling changes: Implications for major protein handling systems in quinone-mediated toxicity

Keywords: سیستم ubiquitin-proteasome; UPS; ubiquitin-proteasome system; HSPs; heat shock proteins; UPR; unfolded protein response; eIF2α; eukaryotic translation initiation factor 2 alpha; LC3; autophagy related microtubule-associated protein 1 light chain 3; NAD(P)H; quinone oxidoreductase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

از دست دادن پروتئازاز ناشی از پپتید بتا آمیلوئید در سلول های اندوتلیال مغزی

Loss of proteostasis induced by amyloid beta peptide in brain endothelial cells

Keywords: سیستم ubiquitin-proteasome; Alzheimer's disease; Amyloid-beta; Autophagy; Endoplasmic reticulum stress; Ubiquitin-proteasome system; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

اهمیت پاتوفیزیولوژیک پروتئین های آسیب دیده جمع شده

Pathophysiological importance of aggregated damaged proteins

Keywords: سیستم ubiquitin-proteasome; Aβ; β-amyloid; AGE; advanced glycation end product (here: proteins modified by AGEs); Atg; autophagy-related gene; CMA; chaperone-mediated-autophagy; 3-DG; 3-deoxyglucosone; FIP200; focal adhesion kinase family-interacting protein of 200 kDa; IP3; inos

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

پیوند مسیرها در مغز در حال رشد و پیری با تولید عصبی

Linking pathways in the developing and aging brain with neurodegeneration

Keywords: سیستم ubiquitin-proteasome; Aβ; amyloid-β; AD; Alzheimer's disease; ALP; autophagy-lysosome pathway; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoER2; apolipoprotein E receptor 2; APP; Aβ precursor protein; BDNF; brain-derived neurotrophic factor; CSF; cere

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2014 سفارش ترجمه

سازگاری استرس اکسیداتیو با استرس حاد، مزمن و مکرر

Oxidative stress adaptation with acute, chronic, and repeated stress

Keywords: سیستم ubiquitin-proteasome; MEF; murine embryonic fibroblast; AMC; 7-amino-4-methylcoumarin; Suc-LLVY-AMC; the succinylated peptide N-succinyl-leucine-leucine-valine-tyrosine-7-amino-4-methylcoumarin (used as a peptide substrate to estimate proteolytic capacity); PBS; phosphate-buff

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

بیماری پارکینسون: از آسیب شناسی به مکانیزم های بیماری مولکولی

Parkinson disease: from pathology to molecular disease mechanisms

Keywords: سیستم ubiquitin-proteasome; SNc; substantia nigra pars compacta; PD; Parkinson disease; NMS; nonmotor symptoms; MAO-B; monoamine oxidase-B; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA; 6-hydroxy dopamine; GBA; glucocerebrosidase; STN

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

اختلال میلوچوندری و سارکوفنیا پیری: از مسیرهای سیگنالینگ تا آزمایشات بالینی

Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials

Keywords: سیستم ubiquitin-proteasome; 31P-NMR; 31P nuclear magnetic resonance; AIF; apoptosis-inducing factor; AngII; angiotensin II; Atg protein; autophagy-related protein; Bcl-2; B-cell leukemia-2; COPD; chronic obstructive pulmonary disease; COX; cytochrome c oxidase; CSA; cross-sectional

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

نقش کلپین ها در اختلال ناشی از آسیب و انحطاط آکسون پستانداران

Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon

Keywords: سیستم ubiquitin-proteasome; AAD; acute axonal degeneration; AIS; axon initial segment; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionate; ankG; ankyrinG; β-APP; β-amyloid precursor protein; CAM; cell adhesion molecule; CAP; compound action potential; Caspr; contactin-associa

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Design, synthesis, and biological evaluation of novel ubiquitin-activating enzyme inhibitors

Keywords: سیستم ubiquitin-proteasome; Small molecules; Ubiquitination; Ubiquitin-proteasome system; Structure-based drug design; Cancer cell growth inhibition;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

TGF-β1 acts as mediator in fluoride-induced autophagy in the mouse osteoblast cells

Keywords: سیستم ubiquitin-proteasome; Autophagy; Fluoride; Mouse osteoblast cell; Proliferation; TGF-β1; ANOVA; one-way analysis of variant; Atg; autophagy-related; BCA; Bicinchoninic Acid; DAPI; 4′,6-diamidino-2-phenylindole; DMEM/F12; Dulbecco's Modified Eagle Medium/F12; ECL; Electro-Ch

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo

Keywords: سیستم ubiquitin-proteasome; MetS; metabolic syndrome; CHD; coronary heart disease; VSMC; vascular smooth muscle cell; UPS; ubiquitin-proteasome system; RNF10; RING finger protein 10; HF; high-fat; FBG; fasting blood glucose; FSI; fasting serum insulin; HOMA-IR; homeostatic model a

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Original ArticleA novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer

Keywords: سیستم ubiquitin-proteasome; DNA damage; DNA repair; Ubiquitin-proteasome system; Triple-negative breast cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA

Keywords: سیستم ubiquitin-proteasome; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; HVA; homovanilic acid; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantia nigra; SNc; substantia nigra pars compacta; SNr; s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Cullin E3 Ligase Activity Is Required for Myoblast Differentiation

Keywords: سیستم ubiquitin-proteasome; UPS; ubiquitin-proteasome system; CRL; Cullin-RING (really interesting new gene) ligase; NAE1; NEDD8 activating enzyme E1 subunit 1; MyHC; myosin heavy chain; siRNA; small interfering RNA; NMJ; neuromuscular junction; AChR; acetylcholine receptor; BTB;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome

Keywords: سیستم ubiquitin-proteasome; 20S Eukaryotic proteasome; Internally quenched peptides; Fluorescence; UPS; ubiquitin-proteasome system; ACC; 7-amino-4-carbamoylmethylcoumarin; AMC; 7-amino-4-methylocoumarin; FRET; fluorescent resonance energy transfer; ABZ; 2-aminobenzoic acid; Tyr(3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5

Keywords: سیستم ubiquitin-proteasome; PRMT5; protein arginine methyltransferase 5; EGFR; epidermal growth factor receptor; TNF; tumor necrosis factor; NF-Y; nuclear factor Y; PKC; protein kinase C; Hsp90; heat shock protein 90; UPS; ubiquitin-proteasome system; CHIP; carboxyl terminus of he

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Trehalose rescues glial cell dysfunction in striatal cultures from HD R6/1 mice at early postnatal development

Keywords: سیستم ubiquitin-proteasome; Huntington disease; Autophagy; Ubiquitin-proteasome system; Trehalose; Glial pathology;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

The role of ubiquitin/Nedd4-2 in the pathogenesis of mesial temporal lobe epilepsy

Keywords: سیستم ubiquitin-proteasome; Mesial temporal lobe epilepsy; Ubiquitin-proteasome system; Ubiquitin; Nedd4-2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2)

Keywords: سیستم ubiquitin-proteasome; CLD; cyclophilin-like domain; CLDm; cyclophilin-like domain mutant; SBM; SUMO-binding motif; Ranbp2; Ran-binding protein 2; Tg; transgenic; UPS; ubiquitin-proteasome system; ubc9; ubiquitin carrier protein 9; SUMO; small ubiquitin-like modifier; RanGAP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Arsenic trioxide induces programmed cell death through stimulation of ER stress and inhibition of the ubiquitin-proteasome system in human sarcoma cells

Keywords: سیستم ubiquitin-proteasome; Sarcoma; Arsenic trioxide; Ubiquitin-proteasome system; Endoplasmic reticulum stress; Autophagy; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Physiological and molecular functions of the cytosolic peptide:N-glycanase

Keywords: سیستم ubiquitin-proteasome; fOSs; free oligosaccharides; Cvt pathway; cytoplasm to vacuole targeting pathway; Dol-PP-OSs; dolichol pyrophosphate-linked oligosaccharides; ENGase; endo-β-N-acetylglucosaminidase; GlcNAc2-IAc; iodoacetamidyl derivative of GlcNAc2; NEF2; nucleotide exci

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of the cardiac proteasome promotes angiotension II-induced hypertrophy by down-regulation of ATRAP

Keywords: سیستم ubiquitin-proteasome; Cardiac hypertrophy; Angiotensin II; Ubiquitin-proteasome system; Bortezomib; Angiotensin II type 1 receptor-associated protein;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model

Keywords: سیستم ubiquitin-proteasome; ALS; amyotrophic lateral sclerosis; fALS; familial ALS; HD; Huntington disease; HspB8; heat shock protein B8; LBHI; Lewy body-like inclusions; mTOR; mammalian target of rapamycin; PBS; phosphate-buffered saline; PD; Parkinson disease; SD; standard deviati

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease

Keywords: سیستم ubiquitin-proteasome; αSyn; alpha-synuclein; ALP; autophagy/lysosomal degradation pathway; CSF; cerebral spinal fluid; ERK5; extracellular-signal-regulated kinase 5; IL; interleukin; KI; knock-in; KO; knockout; LPS; lipopolysaccharide; LRRK2; leucine rich repeat kinase 2; MHC

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology

Keywords: سیستم ubiquitin-proteasome; AAV; adeno-associated virus; AON; antisense oligonucleotide; bp; base pair; Ca2+;  calcium; CaMKII; Ca2+/calmodulin-dependent kinase II; Chr; chromosome; CK2; casein kinase 2; CMH4; hypertrophic cardiomyopathy, locus 4; cMyBP-C; cardiac myosin-binding pr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

The TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscle

Keywords: سیستم ubiquitin-proteasome; Cytokines; NF-κB; Ubiquitin-proteasome system; Autophagy; Sarcopenia;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Insights in cullin 3/WNK4 and its relationship to blood pressure regulation and electrolyte homeostasis

Keywords: سیستم ubiquitin-proteasome; Cullin 3; KLHL3; Hypertension; Ubiquitin-proteasome system; WNK kinases;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of autophagy: Modulation of the size and number of autophagosomes

Keywords: سیستم ubiquitin-proteasome; Ape1; aminopeptidase I; Atg; autophagy-related; ChIP; chromatin immunoprecipitation; Cvt; cytoplasm-to-vacuole targeting; TFEB; transcription factor EB; UPS; ubiquitin-proteasome system; Autophagy; Lysosome; Phagophore; Stress; Vacuole; Yeast;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of histone modifying enzymes by the ubiquitin-proteasome system

Keywords: سیستم ubiquitin-proteasome; Epigenetic code; Histone modification; Histone post-translational modification enzyme; Protein degradation; Ubiquitin-proteasome system; Transcriptional regulation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Ubiquitin at work: The ubiquitous regulation of the damage recognition step of NER

Keywords: سیستم ubiquitin-proteasome; NER; Nucleotide excision repair; UV; Ultraviolet light; CPDs; Cyclobutane pyrimidine dimers; 6-4PPs; 6-4 photoproducts; PTMs; Post-translational modifications; UPS; Ubiquitin-proteasome system; DUB; Deubiquitylating enzyme; DCAFs; DDB1- and CUL4-associa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic ablation of 12/15-lipoxygenase but not 5-lipoxygenase protects against denervation-induced muscle atrophy

Keywords: سیستم ubiquitin-proteasome; ChT; chymotrypsin-like; cPLA2; cytosolic phospholipase A2; NOX; NADPH oxidase; HETE; hydroxyeicosatetraenoic acid; LT; leukotriene; f-ALS; familial amyotrophic lateral sclerosis; LO; lipoxygenase; UPS; ubiquitin-proteasome system; GA; gastrocnemius; TA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Create and preserve: Proteostasis in development and aging is governed by Cdc48/p97/VCP

Keywords: سیستم ubiquitin-proteasome; AAA; ATPase associated with diverse cellular activities; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AMPK; adenosine monophosphate activated kinase; Cdc48/CDC-48; cell division cycle protein 48; DUB; de-ubiquitylating enzyme; ERAD; endopl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond

Keywords: سیستم ubiquitin-proteasome; Ubiquitin-proteasome system; Acetylation; Methylation; Ubiquitination; SUMOylation; Cardiovascular disease;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Interactive effects of CO2 and trace metals on the proteasome activity and cellular stress response of marine bivalves Crassostrea virginica and Mercenaria mercenaria

Keywords: سیستم ubiquitin-proteasome; Ubiquitin-proteasome system; Protein turnover; Ocean acidification; Hypercapnia; Cadmium; Copper;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Substrate recognition in selective autophagy and the ubiquitin-proteasome system

Keywords: سیستم ubiquitin-proteasome; Protein degradation; Selective autophagy; Ubiquitin-proteasome system; Ubiquitination; Substrate recognition; Posttranslational modification;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Protein quality control and elimination of protein waste: The role of the ubiquitin-proteasome system

Keywords: سیستم ubiquitin-proteasome; Protein quality control; Misfolded proteins; Ubiquitin-proteasome system; Chaperones; Protein degradation;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2014 سفارش ترجمه

Proteasome activation delays aging in vitro and in vivo

Keywords: سیستم ubiquitin-proteasome; UPS; ubiquitin-proteasome system; PGPH; peptidyl glutamyl peptide hydrolyzing; T-L; trypsin-like; CT-L; chymotrypsin-like; AD; Alzheimer disease; PD; Parkinson disease; HD; Huntington disease; AMD; age-related macular degeneration; ALS; amyotrophic late

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2014 سفارش ترجمه

Pesticides that inhibit the ubiquitin-proteasome system: Effect measure modification by genetic variation in SKP1 in Parkinson׳s disease

Keywords: سیستم ubiquitin-proteasome; Epidemiology; Gene-environment interaction; Parkinson′s disease; Pesticides; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

Keywords: سیستم ubiquitin-proteasome; Nicotinamide riboside; Alzheimer's disease; β-secretase (BACE1); Promotes peroxisome proliferator-activated receptor (PPAR)-γ coactivator 1 (PGC)-1α; Ubiquitin-proteasome system; Mitochondrial metabolism; Synaptic plasticity; Long-term potentiation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction

Keywords: سیستم ubiquitin-proteasome; Beta cells; Type 2 diabetes; Microarray; Ubiquitin-proteasome system; Lipotoxicity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

FAT10 protects cardiac myocytes against apoptosis

Keywords: سیستم ubiquitin-proteasome; NRCM; neonatal rat cardiac myocytes; H/R; hypoxia/reoxygenation; UPS; ubiquitin-proteasome system; MI; Myocardial infarction; LAD; left anterior descending artery; FITC; fluorescein isothiocyanate; Co-IP; co-immunoprecipitation; Lt-FAT10; lentivirus con

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Gene expression profiling of rotenone-mediated cortical neuronal death: Evidence for inhibition of ubiquitin-proteasome system and autophagy-lysosomal pathway, and dysfunction of mitochondrial and calcium signaling

Keywords: سیستم ubiquitin-proteasome; GSH; glutathione; OXPHOS; oxidative phosphorylation; PD; Parkinson's disease; PCD; programmed cell death; ROS; reactive oxygen species; UPS; ubiquitin-proteasome system; Rotenone; Oxidative stress; Mitochondria complex I inhibition; Programmed cell de

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Basic ScienceInhibition of ERK1/2 pathway suppresses adiponectin secretion via accelerating protein degradation by Ubiquitin-proteasome system: Relevance to obesity-related adiponectin decline

Keywords: سیستم ubiquitin-proteasome; ERK1/2; extracellular signal-regulated kinases 1 and 2; HFD; High-fat diet; UPS; Ubiquitin-proteasome system; TNF-α; tumor necrosis factor-alpha; I PPAR-γ; peroxisome proliferator-activated receptor gamma; ERK1/2; Adiponectin; PPAR-γ; Obesity; Ubiqui

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه