Keywords: ورتمنین; Prostate cancer; Levobupivacaine; Glycolysis; Oxidative phosphorylation; Wortmannin;
مقالات ISI ورتمنین (ترجمه نشده)
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Keywords: ورتمنین; Nanoparticle; Chemoradiotherapy; Nanoparticle radiosensitization; KU60019; Wortmannin; ACN; acetonitrile; ANOVA; analysis of variance; CBC; complete blood count; CRT; chemoradiotherapy; GI; gastrointestinal; Hb; hemoglobin; HCT; hematocrit; mPEG-PLGA; met
Keywords: ورتمنین; Chronic obstructive pulmonary disease (COPD); Phosphoinositide 3-kinase (PI3K); Akt; Wortmannin; Alveolar regeneration;
Keywords: ورتمنین; ATM; ataxia telangiectasia-mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; CI; combination index; CLL; chronic lymphocytic leukemic cells; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit;
Keywords: ورتمنین; rumen protozoa; chemotaxis; wortmannin; phagocytosis;
Keywords: ورتمنین; ACh; acetylcholine; AChE; acetylcholinesterase; aCSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; ChAT; choline acetyltransferase; EGTA; ethylene glycol tetraacetic acid; GFX; GF-109203X; GSK-3; glycogen synthase kinase-3; HD; Huntington'
Keywords: ورتمنین; HCC; hepatocellular carcinoma; K; keratin; IF; intermediate filament; G6P; glucose-6-phosphate; HK; hexokinase; GK; glucokinase; VDAC; voltage-dependent anion channel; GS; glycogen synthase; PI3K; phosphatidylinositol-3 kinase; GSK-3β; glycogen synthase
Low-concentration BPF induced cell biological responses by the ERα and GPER1-mediated signaling pathways in MCF-7 breast cancer cells
Keywords: ورتمنین; ERα/β; (estrogen receptor alpha/beta); GPER1; (G-protein-coupled receptor 1); PI3K/PKB; (phosphatidylinotidol 3-kinase/Protein kinase B); ERK1/2; extracellular-signa1-regulated kinase; ICI; ICI182780; WM; wortmannin; MKH; MK-2206 2HCl; U; U0126; DCFH-DA
Inhibition of tomato fruit ripening by 1-MCP, wortmannin and hexanal is associated with a decrease in transcript levels of phospholipase D and other ripening related genes
Keywords: ورتمنین; CRTISO; carotenoid isomerase; CTR1; constitutive triple response 1; DXS; deoxyxylulose phosphate synthase; ETR; ethylene receptors; GGPS; geranylgeranyl pyrophosphate synthase; 1-MCP; 1-methylcyclopropene; PA; phosphatidic acid; PI; phosphatidylinositol;
Caffeic acid phenethyl ester rescued streptozotocin-induced memory loss through PI3-kinase dependent pathway
Keywords: ورتمنین; Caffeic acid phenethyl ester; PI3-kinase; Memory; Wortmannin; Endothelial NOS; NFκB;
Fasudil hydrochloride ameliorates memory deficits in rat model of streptozotocin-induced Alzheimer's disease: Involvement of PI3-kinase, eNOS and NFκB
Keywords: ورتمنین; Fasudil; PI3-kinase; Wortmannin; Endothelial NOS; NFκB; Memory; Acetylcholinesterase;
PI3K-AKT-GSK3β-CREB signaling pathway regulates anxiety-like behavior in rats following alcohol withdrawal
Keywords: ورتمنین; Alcohol withdrawal; Anxiety-like behavior; PI3K-AKT-GSK3β-CREB signaling pathway; The medial prefrontal cortex; Wortmannin;
Raffinose from Costus speciosus attenuates lipid synthesis through modulation of PPARs/SREBP1c and improves insulin sensitivity through PI3K/AKT
Keywords: ورتمنین; Anti-diabetes; Anti-adipogenesis; Lipid metabolism; Insulin signaling; ACC; acetyl-CoA carboxylase; ACO; Acyl CoA Oxidase; Comp C; Compound C; CSEW; Costus speciosus ethanolic water extract; DMEM; Dulbecco's Modified Eagle Medium; FAS; fatty acid synthase
Osmotic stress induced toxicity exacerbates Parkinson's associated effects via dysregulation of autophagy in transgenic C. elegans model
Keywords: ورتمنین; PD; Parkinson's disease; α-synuclein; alpha-synuclein; C.elegans; Caenorhabditis elegans; ROS; reactive oxygen species; NGM; nutrient growth medium; H2-DCF-DA; 2, 7-dichlorodihydrofluorescein-diacetate; SP; spermidine; WT; wortmannin; HN; high osmotic; L
Inhibition of phosphatidylinositol-3-kinase by the furanosesquiterpenoid hibiscone C
Keywords: ورتمنین; Hibiscone C; Wortmannin; PI3K; Furanosteroid; Furanosesquiterpenoid;
Phytol increases adipocyte number and glucose tolerance through activation of PI3K/Akt signaling pathway in mice fed high-fat and high-fructose diet
Keywords: ورتمنین; Adipocyte number; Adipogenesis; Glucose tolerance; Phytol; PI3K/Akt; Mice; Akt; protein kinase B; aP2; adipocyte protein 2; AS160; Akt substrate of 160 kDa; AUC; area under the curve; C/EBPα; CCAAT-enhancer-binding proteins; FoxO1; Forkhead box protein
In situ detection of the activation of Rac1 and RalA small GTPases in mouse adipocytes by immunofluorescent microscopy following in vivo and ex vivo insulin stimulation
Keywords: ورتمنین; DMEM; Dulbecco's modified Eagle's medium; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GST; glutathione S-transferase; HA; hemagglutinin; m-rac1-KO; muscle-specific rac1 knockout; Myr-p110α; myristoylated p110α; PBS; phosphat
Pharbitis Nil (PN) induces apoptosis and autophagy in lung cancer cells and autophagy inhibition enhances PN-induced apoptosis
Keywords: ورتمنین; PN; Pharbitis Nil; ERK1/2; Extracellular signal-regulated kinases 1 and 2; STAT3; Signal transducer and activator of transcription 3, RT-PCR, Reverse transcriptase -polymerase chain reaction; siRNA; Small interfering RNA; PARP; poly ADP-ribose polymerase;
Insulin promotes cell migration by regulating PSA-NCAM
Keywords: ورتمنین; PSA; polysialic acid; NCAM; neural cell adhesion molecule; ECM; membrane-like extracellular matrix; INS; insulin; WT; wortmannin; PF; PF-562271; p-Akt; phosphorylated Akt; p-FAK; phosphorylated focal adhesion kinase; RTKs; receptor tyrosine kinases; IR-β
Loss of ErbB2-PI3K/Akt signaling prevents zinc pyrithione-induced cardioprotection during ischemia/reperfusion
Keywords: ورتمنین; ATP; adenosine triphosphate; AAR; area at risk; AG825; (E)-3-[3-[2-benzothiazolythio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide; B10; anti-ErbB2 blocking antibody; BSA; bovine serum albumin; CK; creatine kinase; DAF; diaminofluorescein; DEVD
Withaferin A induced impaired autophagy and unfolded protein response in human breast cancer cell-lines MCF-7 and MDA-MB-231
Keywords: ورتمنین; AO; Acridine orange; AVOs; Acidic vesicular organelles; CT; Chymotrypsin; LC3; Microtubule associated light chain 3; MDC; Mono-Dansyl-Cadaverine; UPS; Ubiquitin-proteasome system; WA; Withaferin A; WT; Wortmannin; EtBr; Ethidium Bromide; SQSTM1; Sequestos
The photodynamic action of pheophorbide a induces cell death through oxidative stress in Leishmania amazonensis
Keywords: ورتمنین; AA; antimycin A; CCCP; cyanide m-chlorophenylhydrazone; DAF-FM diacetate; 4-amino-5-methylamino-2â²,7â²-difluoro fluoresceÃn; DMSO; dimethylsulfoxide; DPPP; diphenyl-1-pyrenylphosphine; DTNB; 2,2â²-dinitro-5,5â²-dithiobenzoic acid; FBS; fetal bovine
Cellular uptake and intracellular localization of poly (acrylic acid) nanoparticles in a rainbow trout (Oncorhynchus mykiss) gill epithelial cell line, RTgill-W1
Keywords: ورتمنین; CavME; caveolae-mediated endocytosis; CMDR; CellMask Deep Red; CTb; cholera toxin B subunit; CTb-FITC; cholera toxin B subunit-fluorescein isothiocyanate; CPZ; chlorpromazine; CME; clathrin-mediated endocytosis; DAPI; 4â² 6-diamidino-2-phenylindole; ddH2
Pharmacological inhibition of PI3K class III enhances the production of pro- and anti-inflammatory cytokines in dendritic cells stimulated by TLR agonists
Keywords: ورتمنین; Wortmannin; PI3K; Vps34; Dendritic cells; IL-10;
Oestrogen exerts anti-inflammation via p38 MAPK/NF-κB cascade in adipocytes
Keywords: ورتمنین; LPS; lipopolysaccharides; MCP-1; monocyte chemoattractant protein-1; E2; 17β-estradiol; ERoestrogen; receptor; SB; SB203580; PDTC; pyrrolidine dithiocarbamate; PTX; pertussis toxin; WM; wortmannin; PPT; trisphenol; DPN; 2,3-bis-(4-hydroxyphenyl)-propioni
Specific role of cytoplasmic dynein in the mechanism of action of an antitumor molecule, Amblyomin-X
Keywords: ورتمنین; BTZ; bortezomib; FDA; Food and Drug Administration; Arf6; ADP-ribosylation factor 6; LR; lipid raft; EE; early endosomes; SE; sorting endosomes; ERC; endocytic recycling compartment; RE; recycling endosome; LE; late endosomes; Rab; Ras superfamily of mono
Autophagy sustains the survival of human pancreatic cancer PANC-1 cells under extreme nutrient deprivation conditions
Keywords: ورتمنین; Autophagy; PANC-1; Extreme nutrient deprivation; Apoptosis; Survival; AMPK; 5â² adenosine monophosphate-activated protein kinase; CQ; chloroquine; LC3; microtubule-associated protein 1A/1B-light chain 3; mTOR; mammalian target of rapamycin; PDAC; pancrea
Neuroprotective role of sphingosine-1-phosphate in L-BMAA treated neuroblastoma cells (SH-SY5Y)
Keywords: ورتمنین; S1P; sphingosine-1-phosphate; L-BMAA; S(+)-2-amino-3-(methylamino) propionic acid; GSK3; glycogen synthase kinase-3; ALS; amyotrophic lateral sclerosis; Wrt; wortmannin; SH-SY5Y; Sphingosine-1-phosphate; β-N-methylamine-l-alanine; Neuroprotection; GSK3;
PI3K/Akt/p53 pathway inhibits reovirus infection
Keywords: ورتمنین; CHT; α-Chymotrypsin; LY; LY294002; Wort; Wortmannin; p-Akt; phosphorylated Akt; p-MDM2; phosphorylated MDM2; Reovirus; PI3K/Akt; p53; MDM2; Replication;
Aldosterone stimulates the cardiac sodium/bicarbonate cotransporter via activation of the g protein-coupled receptor gpr30
Keywords: ورتمنین; Ald; aldosterone; NHE-1; Na+/H+ exchanger; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; MPG; N-(2-mercapto-propionyl)glycine; ROS; reactive oxygen species; NBC; Na+/HCO3â cotransporter; Apo; apocynin; Wort; wortmannin; eple; epl
Pharmacogenomic and molecular docking studies on the cytotoxicity of the natural steroid wortmannin against multidrug-resistant tumor cells
Keywords: ورتمنین; Wortmannin; Fusarium oxysporum; ABC-transporter; Cluster analysis; Drug resistance; Kinase inhibitor; Microarrays; Molecular docking;
The PI3K–Akt–eNOS pathway is involved in aortic hyporeactivity to Phenylephrine associated with late pregnancy in spontaneously hypertensive rats
Keywords: ورتمنین; Wortmannin; Aorta; Phenylephrine; Pregnancy; Nitric oxide; Spontaneously hypertensive rats
The activation of PI 3-kinase/Akt pathway is involved in the acute effects of simvastatin against ischaemia and reperfusion-induced arrhythmias in anaesthetised dogs
Keywords: ورتمنین; Simvastatin; Nitric oxide; Ischaemia/reperfusion; Arrhythmias; Wortmannin
Arabidopsis dynamin-related proteins, DRP2A and DRP2B, function coordinately in post-Golgi trafficking
Keywords: ورتمنین; BiFC; bi-molecular fluorescent complementation; CLSM; confocal laser scanning microscopy; CoIP-MS; co-immunoprecipitation mass spectrometry; DRP; dynamin-related protein; GED; GTPase-effector domain; Lat B; latrunculin B; ORY; oryzalin; PH; pleckstrin hom
Direct antiapoptotic effects of growth hormone are mediated by PI3K/Akt pathway in the chicken bursa of Fabricius
Keywords: ورتمنین; Growth hormone; IGF-I; Bursa of Fabricius; Apoptosis; PI3K/Akt pathway; Wortmannin;
PI3K is involved in nucleolar structure and function on root-tip meristematic cells of Triticum aestivum L.
Keywords: ورتمنین; Wortmannin; Root-tip meristematic cell; Nucleolar structure; Nucleolar function; Triticum aestivum L.
Nobiletin, a polymethoxy flavonoid, exerts anti-allergic effect by suppressing activation of phosphoinositide 3-kinase
Keywords: ورتمنین; BMMC; bone marrow-derived mast cell; BSA; bovine serum albumin; [Ca2+]i; intracellular Ca2+ concentration; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulphoxide; DNP; dinitrophenol; FBS; fetal bovine serum; FcεRI; high-affinity IgE rece
Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs
Keywords: ورتمنین; Pancreatic cancer; Autophagy; Chemotherapy; PANC-1; BxPC-3; 5-Fluorouracil; Gemcitabine; Chloroquine; Wortmannin; LC3
Effects of wortmannin, sodium nitroprusside, insulin, genistein, and guanosine triphosphate on chemotaxis and cell growth of Entodinium caudatum, Epidinium caudatum, and mixed ruminal protozoa
Keywords: ورتمنین; rumen protozoa; chemotaxis; wortmannin; insulin;
Hyperglycemia-induced oxidative stress induces apoptosis by inhibiting PI3-kinase/Akt and ERK1/2 MAPK mediated signaling pathway causing downregulation of 8-oxoG-DNA glycosylase levels in glial cells
Keywords: ورتمنین; DHE; dihydroethidium; DHR; dihydrorodamine 123; HG; high glucose; LY; LY294002; LPO; lipid peroxidation; NBT; nitrotetrazolium blue; PC; protein carbonylation; U1; PD98059; U2; U0126; WT; wortmannin; Glial cells; Hyperglycemia; Oxidative-nitrosative stres
Overexpression of HSPA12B protects against cerebral ischemia/reperfusion injury via a PI3K/Akt-dependent mechanism
Keywords: ورتمنین; I/R; ischemia/reperfusion; BBB; Blood-brain-barrier; HSPs; Heat shock proteins; HSPA12B; Heat shock protein A12B; PI3K/Akt; phosphoinositide 3-kinase/protein kinase B; TTC; 2,3,5-triphenyltetrazolium chloride; WM; Wortmannin; Cerebral ischemia/reperfusi
Poly(ADP-ribose) polymerase inhibition protects epileptic hippocampal neurons from apoptosis via suppressing Akt-mediated apoptosis-inducing factor translocation in vitro
Keywords: ورتمنین; AE; acquired epilepsy; AIF; apoptosis-inducing factor; CLSM; confocal laser scanning microscopy; DPQ; 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HNC; hippocampal neuronal cultur
Neuro-protective effects of growth hormone (GH) after hypoxia-ischemia injury in embryonic chicken cerebellum
Keywords: ورتمنین; Growth hormone (GH); Neuroprotection; Hypoxia and low glucose (HLG); Anti-apoptotic effects; PI3K/Akt; Wortmannin;
Viridin analogs derived from steroidal building blocks
Keywords: ورتمنین; PI-3K; Wortmannin; Viridin; Steroid; Irreversible enzyme inhibitors;
PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter
Keywords: ورتمنین; ABC, ATP-binding cassette; PI3K, phosphatidylinositol 3-kinase; mTOR, mammalian target of rapamycin; MDR, multidrug resistanceABCG2; PI3-kinase/Akt/mTOR signaling; LY294002; Wortmannin; Rapamycin
Evidence for phosphatidylinositol-3-OH-kinase (PI3-kinase) involvement in Cd-mediated oxidative effects on hemocytes of mussels
Keywords: ورتمنین; Cadmium; Hemocytes; Lipid peroxidation; Nitric oxide; PI3-kinase; PKC; Superoxide; Wortmannin;
Uptake of fluorescent nano beads into BY2-cells involves clathrin-dependent and clathrin-independent endocytosis
Keywords: ورتمنین; IKA; Ikarugamycin; Fluorescent nano bead; Clathrin-independent endocytosis; Clathrin-dependent endocytosis; IKA; Wortmannin; BY-2;
The Stress-Induced Cytokine Interleukin-6 Decreases the Inhibition/Excitation Ratio in the Rat Temporal Cortex via Trans-Signaling
Keywords: ورتمنین; 2-Br-hexadecanoic acid; postsynaptic; Brefeldin A; dynamin inhibitory peptide; foot-shock; γ-aminobutyric acid (GABA); interleukin-6 (IL-6); lipopolysaccharide (LPS); PI3K/AKT; patch-clamp; stress; gp130; rat; temporal cortex; trans-signaling; wortmannin
DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates
Keywords: ورتمنین; Gapped DNA synthesis; Wortmannin; NU7441; DNA-PKcs; Alternative NHEJ; Microhomology;
Prevention of the wortmannin-induced inhibition of phosphoinositide 3-kinase by sulfhydryl reducing agents
Keywords: ورتمنین; wortmannin; sulfhydryl reducing agent; phosphoinositide 3-kinase; PI3K; 2-mercaptoethanol; dithiothreitol