Mass-spectrometry-based metabolomics analysis for foodomics

• The current state of MS-based metabolic profiling methods in food science.
• Multi-disciplinary approaches needed to link food and diet with health and disease.
• Foodomics characterizes food composition, quality assurance, nutrition and health.
• Challenges in developing metabolomics approaches for foodomics applications.

Mass spectrometry (MS) has gained popularity in metabolomics due to its unparalleled sensitivity and specificity, high resolution and wide dynamic range. MS-based metabolomics techniques have driven the emergence of a new omics sub-discipline – foodomics. In this review, we present the current state of MS-based metabolomics and typical applications in food science related to food composition, food safety, quality, nutrition and health.