کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1671481 | 1008917 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Towards nanoporous polymer thin film-based drug delivery systems
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
فناوری نانو (نانو تکنولوژی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Towards nanoporous polymer thin film-based drug delivery systems Towards nanoporous polymer thin film-based drug delivery systems](/preview/png/1671481.png)
چکیده انگلیسی
A nanoporous polymer thin film has been developed as a potential platform for drug delivery. The film was fabricated by a light-induced polymerization process in which non-reactive solvent was first separated from photopolymer (dipentaerythritol penta-/hexa-acrylate as the monomer) and then removed from polymer via evaporation, yielding pores with diameters between 20 and 40Â nm. Loading and release of Rhodamine B (drug model molecules) on both porous and non-porous thin films proved that nanopores enhanced the film's effectiveness in encapsulating and releasing the drug model molecules, which was attributed to the high surface-to-volume ratio of nanoporous film. Ultrasound-enhanced cumulative and pulsatile release revealed the advantages of ultrasound in controlled drug delivery.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thin Solid Films - Volume 517, Issue 5, 1 January 2009, Pages 1794-1798
Journal: Thin Solid Films - Volume 517, Issue 5, 1 January 2009, Pages 1794-1798
نویسندگان
Wei Yan, Vincent K.S. Hsiao, Yue Bing Zheng, Yasir M. Shariff, Tieyu Gao, Tony Jun Huang,