کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2576014 | 1561326 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mirtazapine associated with profound hyponatremia: Two case reports
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب سالمندان و علم پیری شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Conclusions: The likelihood of mirtazapine use causing hyponatremia in these 2 cases was “probable” according to criteria of the Naranjo Adverse Drug Reaction Probability Scale (score, 6). A review of published cases found that mirtazapine-associated hyponatremia occurred in patients aged >60 years, after a mean of 6.5 days and with doses as low as 7.5 mg daily. The mean sodium nadir was 117.2 mEq/L, but after stopping mirtazapine, the mean time to recovery was 11 days. Clinicians should be aware of the possibility of this reaction in elderly patients and should monitor sodium levels in high-risk patients if symptoms suggestive of hyponatremia develop.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Geriatric Pharmacotherapy - Volume 6, Issue 2, June 2008, Pages 91-95
Journal: The American Journal of Geriatric Pharmacotherapy - Volume 6, Issue 2, June 2008, Pages 91-95
نویسندگان
Chan Y. MBBS, Bronwyn BPharm, P. Gerry MBChB, MRCP, MD,