کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2999915 | 1180309 | 2011 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Vitamin D Insufficiency
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کلمات کلیدی
HRTBMDNHANESRCTpTH1,25(OH)2D - 1،25 (OH) 2D1,25-dihydroxyvitamin D - 1،25-دی هیدروکسوییتامین D25(OH)D - 25 (OH) D25-hydroxyvitamin D - 25 هیدروکسی ویتامین DRandomized controlled trial - آزمایش تصادفی کنترل شدهWomen's Health Initiative - ابتکار بهداشت زنانNational Health and Nutrition Examination Survey - بررسی بهداشت و تغذیه ملیBone mineral density - تراکم معدنی استخوانRelative risk - خطر نسبیconfidence interval - فاصله اطمینانhazard ratio - نسبت خطرodds ratio - نسبت شانس هاhormone replacement therapy - هورمون جایگزین درمانparathyroid hormone - هورمون پاراتیروئیدwhi - وای
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Vitamin D deficiency, which classically manifests as bone disease (either rickets or osteomalacia), is characterized by impaired bone mineralization. More recently, the term vitamin D insufficiency has been used to describe low levels of serum 25-hydroxyvitamin D that may be associated with other disease outcomes. Reliance on a single cutoff value to define vitamin D deficiency or insufficiency is problematic because of the wide individual variability of the functional effects of vitamin D and interaction with calcium intakes. In adults, vitamin D supplementation reduces the risk of fractures and falls. The evidence for other purported beneficial effects of vitamin D is primarily based on observational studies. We selected studies with the strongest level of evidence for clinical decision making related to vitamin D and health outcomes from our personal libraries of the vitamin D literature and from a search of the PubMed database using the term vitamin D in combination with the following terms related to the potential nonskeletal benefits of vitamin D: mortality, cardiovascular, diabetes mellitus, cancer, multiple sclerosis, allergy, asthma, infection, depression, psychiatric, and pain. Conclusive demonstration of these benefits awaits the outcome of controlled clinical trials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 86, Issue 1, January 2011, Pages 50-60
Journal: Mayo Clinic Proceedings - Volume 86, Issue 1, January 2011, Pages 50-60
نویسندگان
Tom D. MD, Bart L. MD,