کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3181138 | 1200545 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
SÃndrome de hipersensibilidad inducido por sulfasalazina asociado a reactivación de VHH-6 e inducción de sÃndrome antifosfolÃpido
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
امراض پوستی
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![عکس صفحه اول مقاله: SÃndrome de hipersensibilidad inducido por sulfasalazina asociado a reactivación de VHH-6 e inducción de sÃndrome antifosfolÃpido SÃndrome de hipersensibilidad inducido por sulfasalazina asociado a reactivación de VHH-6 e inducción de sÃndrome antifosfolÃpido](/preview/png/3181138.png)
چکیده انگلیسی
Drug-induced hypersensitivity syndrome is a toxicoderma with systemic involvement. Suspicion of this disorder obliges rapid withdrawal of the suspected drug, which may have been introduced up to 3 months earlier. Screening for human herpesvirus (HHV) 6 reactivation is important both for its diagnostic value and for its association with a poor prognosis. Reactivation of this virus is not a contraindication for systemic corticosteroid treatment, which should be tapered slowly in order to avoid recurrence. The possible appearance of antiphospholipid antibodies must also be considered in those cases associated with thrombocytopenia, altered hemostasis, or thrombotic events. Autoimmune disorders may also develop as a sequela of the condition. Medium-to-long-term follow-up is required even after complete resolution of the condition. We describe a new case of sulfasalazine-induced hypersensitivity syndrome associated with HHV-6 reactivation and the induction of anticardiolipin and anti-thyroid peroxidase antibodies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Actas Dermo-Sifiliográficas - Volume 102, Issue 7, September 2011, Pages 537-540
Journal: Actas Dermo-Sifiliográficas - Volume 102, Issue 7, September 2011, Pages 537-540
نویسندگان
Y. Tung, B. Escutia, M. Blanes, M. Navarrro, C. Pujol,