کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3198858 1201901 2011 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response
چکیده انگلیسی
Our study shows that resolution of clinical disease in patients with chronic AD is accompanied by reversal of both the epidermal defects and the underlying immune activation. We have defined a set of biomarkers of disease response that associate resolved TH2 and T22 inflammation in patients with chronic AD with reversal of barrier pathology. By showing reversal of the AD epidermal phenotype with a broad immune-targeted therapy, our data argue against a fixed genetic phenotype.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 128, Issue 3, September 2011, Pages 583-593.e4
نویسندگان
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