کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3199610 | 1201916 | 2011 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis](/preview/png/3199610.png)
چکیده انگلیسی
There is a reduction in AMP PC threshold but not histamine PC threshold during the pollen season, indicating that AMP is a more sensitive indicator of allergic inflammation. The residual hyperreactivity to nasal AMP, but not histamine, outside of the pollen season, seen as a persistently prolonged recovery curve, suggests the presence of primed airway mucosal mast cells, even in asymptomatic patients, and persistent activation of mediator pathways, such as cysteinyl leukotrienes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 127, Issue 1, January 2011, Pages 173-178.e3
Journal: Journal of Allergy and Clinical Immunology - Volume 127, Issue 1, January 2011, Pages 173-178.e3
نویسندگان
Sriram MBBS, Peter MBChB, Karine MBChB, Ashley MSc, Brian MD,