Immunosuppression of TH2 responses in Trichinella spiralis infection by Helicobacter pylori neutrophil-activating protein

This study provides evidence that HP-NAP enhances endogenous IL-12 and IFN-γ response and exerts a powerful anti-TH2 activity in vivo, targeting both IL-5-induced eosinophilia and IL-4-mediated hyper-IgE responses induced by parasitic infection.