کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3204449 | 1587148 | 2013 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Management of Eosinophilic Esophagitis
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
QOLGERDNLREGDPLREoETGFproton pump inhibitor–responsive esophageal eosinophiliaPSTOCshpfAPTPPVPPITCSSFEDOVBPrick skin testQuality of life - کیفیت زندگیAtopy patch test - آزمایش اتوپی پچAtopy patch testing - آزمایش اتوپی پچEosinophil - ائوزینوفیلpositive predictive value - ارزش پیش بینی مثبتnegative predictive value - ارزش پیش بینی منفیEoE, Eosinophilic esophagitis - ازوفاژیت ائوزینوفیلیکesophagogastroduodenoscopy - اوسوفاژوگاسترودوداندوسکوپی، اندوسکوپی دستگاه گوارش فوقانیimmunoglobulin - ایمونوگلوبولینTigers - ببرهاgastroesophageal reflux disease - بیماری ریفلاکس معده به مریtransforming growth factor - تبدیل فاکتور رشدskin testing - تست پوستGastrointestinal - دستگاه گوارشelemental diet - رژیم عنصریsix-food elimination diet - رژیم غذایی حذف شش غذاElimination diet - رژیم لاغریFluticasone propionate - فلوتیکازون پروپیوناتdietary management - مدیریت رژیم غذاییNPV یا negative predictive value - مقادیر پیش بینی شده منفیProton pump inhibitor - مهار کننده پمپ پروتونhigh-powered field - میدان مغناطیسیpositive likelihood ratio - نسبت احتمال مثبتnegative likelihood ratio - نسبت احتمال منفیtopical corticosteroids - کورتیکواستروئیدهای موضعی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Eosinophilic esophagitis (EoE) is a clinicopathologic, chronic esophageal inflammatory disease resistant to acid suppressive therapy and is associated with variable symptoms indicative of upper gastrointestinal dysfunction. Per current guidelines established by The International Group of Eosinophil Researchers (TIGERS), the diagnosis is made in symptomatic patients after a biopsy that confirms a peak eosinophil level of â¥15 eosinophils/high-powered field (HPF). The esophagus is distinguished by pronounced tissue eosinophilia in which dietary antigens are key inciting factors for disease pathogenesis; EoE being reversed by elimination of triggering food allergens suggests that the disease is mediated in part by allergic sensitization to foods. Moreover, experimental EoE in mice can be induced not only via food exposure but also via aeroallergen exposure. Consistent with an allergic etiology rather than an acid-induced esophagitis, swallowed glucocorticoids are effective for the treatment of EoE. Evaluation by an allergist is a recommended part of the diagnostic workup, especially for management of allergic comorbidities. Clinical practice for the evaluation of patients with EoE mainly relies on prick skin tests due to the ease and validation of these tests in the context of immediate hypersensitivity. However, both atopy patch testing and serum IgE testing have been used in EoE. Herein, we reviewed the basic clinical features of EoE with a focus on the approach to diagnosing causative food allergens and to dietary therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 1, Issue 4, JulyâAugust 2013, Pages 332-340
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 1, Issue 4, JulyâAugust 2013, Pages 332-340
نویسندگان
Matthew MD, MBA, MSc, Seema S. MD, PhD, Jonathan M. MD, PhD, Marc E. MD, PhD,