کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3205137 1587526 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Predictive value of biopsy specimens suspicious for melanoma: Support for 6-mm criterion in the ABCD rule
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
پیش نمایش صفحه اول مقاله
Predictive value of biopsy specimens suspicious for melanoma: Support for 6-mm criterion in the ABCD rule
چکیده انگلیسی

ObjectiveClinical detection of melanoma can be challenging. The number of biopsy specimens performed to diagnose 1 melanoma is a measure of efficiency of skin cancer detection, but few data are available to describe this measure from US health care. We studied the diagnosis of melanoma among biopsy specimens of clinically concerning pigmented lesions at an academic dermatology department.MethodsWe searched for all biopsy specimens that were performed because of clinical suspicion of melanoma in 2013. Characteristics of the patient, lesion, and clinician performing the biopsy, and the final pathology diagnosis were recorded.ResultsA total of 2643 biopsy specimens from 2213 patients submitted by 43 providers were included. Melanoma was diagnosed in 165 cases (positive predictive value 6.4%, 95% confidence interval 5.5%-7.4%). Older age (P < .001), male gender (P = .045), and nontrunk location (P < .001) were predictors of higher probability of melanoma detection. Lesions larger than 6 mm in size had higher positive predictive value 11.5% (8.8%-14.1%) than smaller lesions 2.6% (1.6%-3.6%).LimitationsFactors influencing the decision to biopsy a lesion may be difficult to evaluate retrospectively.ConclusionAt an academic medical center, 16 clinically concerning lesions were biopsied to diagnose 1 melanoma. Biopsy specimens of clinically concerning pigmented lesions larger than 6 mm on older men had the highest yield.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Dermatology - Volume 72, Issue 3, March 2015, Pages 412–418
نویسندگان
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