کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3206576 1587571 2011 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Spitz nevi and other Spitzoid lesions : Part I. Background and diagnoses
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
پیش نمایش صفحه اول مقاله
Spitz nevi and other Spitzoid lesions : Part I. Background and diagnoses
چکیده انگلیسی

Spitz nevi are melanocytic proliferations that are characterized by spindled and/or epithelioid nevomelanocytes. First interpreted as juvenile melanoma, these lesions were later characterized as benign and were observed to affect all age groups. Today, contrasting opinions persist regarding the fundamental benignancy versus malignancy within the spectrum of Spitz tumors. Beyond clinical outcome, this controversy has also been fueled by complex and sometimes convoluted classification schemes based on pathologic characteristics. More recently, immunophenotypic and molecular analyses have begun to clarify the etiologic nature of these tumors. Recent evidence suggests that histopathologic features that suggest more aggressiveness in Spitz tumors relate to mitoses and inflammation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Dermatology - Volume 65, Issue 6, December 2011, Pages 1073–1084
نویسندگان
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