Dietary glycemic index and glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels in patients with acne

BackgroundSeveral isolated observations have suggested that acne can develop in groups when a high glycemic index diet is adopted.ObjectiveThis study was designed to examine associations among daily diet glycemic index, glycemic loads, serum insulin levels, and acne.MethodsA total of 49 patients with acne and 42 healthy control subjects were included in the study. At the initial visit, fasting glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels were measured. A voluntary self-completed questionnaire was administered and participants were asked how frequently they consumed the specified amount of food. Overall glycemic index and dietary glycemic load were calculated.ResultsNo significant differences were observed between patients with acne and control subjects in serum glucose, insulin, leptin levels, overall glycemic index, or dietary glycemic load.LimitationsThe information and data obtained from this questionnaire were limited to patients' own recollections.ConclusionResults of this study indicate that dietary glycemic index, glycemic load, and insulin levels do not have a role in pathogenesis of acne in younger patients.