کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3211509 1587639 2007 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of a high-protein, low glycemic–load diet versus a conventional, high glycemic–load diet on biochemical parameters associated with acne vulgaris: A randomized, investigator-masked, controlled trial
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
پیش نمایش صفحه اول مقاله
The effect of a high-protein, low glycemic–load diet versus a conventional, high glycemic–load diet on biochemical parameters associated with acne vulgaris: A randomized, investigator-masked, controlled trial
چکیده انگلیسی

BackgroundNo previous study has sought to examine the influence of dietary composition on acne vulgaris.ObjectiveWe sought to compare the effect of an experimental low glycemic–load diet with a conventional high glycemic–load diet on clinical and endocrine aspects of acne vulgaris.MethodsA total of 43 male patients with acne completed a 12-week, parallel, dietary intervention study with investigator-masked dermatology assessments. Primary outcomes measures were changes in lesion counts, sex hormone binding globulin, free androgen index, insulin-like growth factor-I, and insulin-like growth factor binding proteins.ResultsAt 12 weeks, total lesion counts had decreased more in the experimental group (−21.9 [95% confidence interval, −26.8 to −19.0]) compared with the control group (−13.8 [−19.1 to −8.5], P = .01). The experimental diet also reduced weight (P = .001), reduced the free androgen index (P = .04), and increased insulin-like growth factor binding protein-1 (P = .001) when compared with a high glycemic–load diet.LimitationsWe could not preclude the role of weight loss in the overall treatment effect.ConclusionThis suggests nutrition-related lifestyle factors play a role in acne pathogenesis. However, these preliminary findings should be confirmed by similar studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Dermatology - Volume 57, Issue 2, August 2007, Pages 247–256
نویسندگان
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