Modèle de pseudotumeur pour guider l'ablation thermique par ultrasons focalisés : étude sur le porc

There is no established liver tumour model in pigs to study the efficacy of ablative treatment options available for the treatment of liver tumours by physical agents. A tumour-mimic model visible with high contrast on sonograms and on gross pathology has been studied at mid-term on 20 pigs. The aim was to determine if these tumour-mimics are well tolerated and can be used to validate the use of thermal therapies at a preclinical stage. The dimensions of the tumour-mimics measured on sonograms were reproducible (diameter: 9.6 ± 1.9 mm) and correlated with those performed in gross pathology (R2 = 0.73). The accuracy of focused ultrasound thermal therapy can be evaluated preclinically using these tumour-mimics.