کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5644465 | 1586546 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Pacjentka z ciÄżkÄ
astmÄ
wyÅÄ
czona z leczenia omalizumabem po 12 tygodniach
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی و میکروب شناسی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We present the case of 20-year-old woman with the short history of severe course of asthma since its beginning. The patient met the inclusion criteria to omalizumab therapy in the program reimbursed by Polish Health Fund, so we expected that this therapy will enable to improve asthma control in the patient and decrease the dose of oral steroids or completely withdraw them. However within twelve weeks of therapy, the day of omalizumab application had to be rescheduled many times because of infectious asthma exacerbations. Moreover, in between exacerbations, asthma remained uncontrolled in spite of the very high doses of inhaled steroids and bronchodilators. Only on the day of last omalizumab injection, the patient reported better condition, and we observed improvement in spirometry and questionnaires score. We hoped that patient started to respond to the therapy. In the twelfth week of therapy, the patient reported that she became pregnant and had to be excluded from the therapeutical program. From the patients' findings, high eosinophil count in peripheral blood as well as in broncho-alveolar lavage fluid were remarkable and chronic sinusitis preceded asthma diagnose.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Alergologia Polska - Polish Journal of Allergology - Volume 3, Supplement 1, NovemberâDecember 2016, Pages S14-S17
Journal: Alergologia Polska - Polish Journal of Allergology - Volume 3, Supplement 1, NovemberâDecember 2016, Pages S14-S17
نویسندگان
Agnieszka Gawlewicz-Mroczka, Marek Przybyszowski, Weronika ZastrzeżyÅska, Krzysztof SÅadek,