کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5646330 1407063 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mast cell activation syndromes
ترجمه فارسی عنوان
سندرم فعال سازی سلول های مادرم
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
چکیده انگلیسی

Mast cell activation is common and possibly necessary for maintenance of survival. Disordered mast cell activation occurs when mast cells are pathologically overproduced or if their activation is out of proportion to the perceived threat to homeostasis. Mast cell activation syndrome refers to a group of disorders with diverse causes presenting with episodic multisystem symptoms as the result of mast cell mediator release. Despite introduction of diagnostic criteria and some advances in treatment in the last decade, many areas of mast cell activation syndrome are in need of research. This article reviews our current knowledge about the various types of mast cell activation disorders, their treatment, and areas of uncertainty in need of future investigation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 140, Issue 2, August 2017, Pages 349-355
نویسندگان
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