کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5647565 | 1587126 | 2017 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Current Evidence on Safety and Practical Considerations for Administration of Sublingual Allergen Immunotherapy (SLIT) in the United States
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کلمات کلیدی
SARFDASublingual allergen immunotherapySCITSLITAITEoEHDMICSFEV1WAO - از آنهاEoE, Eosinophilic esophagitis - ازوفاژیت ائوزینوفیلیکsubcutaneous allergen immunotherapy - ایمونوتراپی آلرژیک زیر جلدیAllergen specific immunotherapy - ایمونوتراپی ویژه آلرژنWorld Allergy Organization - سازمان جهانی آلرژیFood and Drug Administration - سازمان غذا و داروLar - لارforced expiratory volume in 1 second - مجاز خروج مجدد در 1 ثانیهSystemic allergic reaction - واکنش آلرژیک سیستمیکInhaled corticosteroid - کورتیکواستروئیدهای استنشاقی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Liquid sublingual allergen immunotherapy (SLIT) has been used off-label for decades, and Food and Drug Administration (FDA)-approved grass and ragweed SLIT tablets have been available in the United States since 2014. Potentially life-threatening events from SLIT do occur, although they appear to be very rare, especially for FDA-approved products. Practice guidelines that incorporate safety precautions regarding the use of SLIT in the United States are needed. This clinical commentary attempts to address unresolved issues including controversy regarding the FDA mandate for the prescription of epinephrine autoinjectors for patients on SLIT; how to approach polysensitized patients; optimal timing and duration of SLIT administration; how to address gaps in therapy; whether antihistamines can prevent local reactions, if certain patient populations (such as persistent asthmatics) should not receive SLIT; and when to instruct patients to self-administer epinephrine. Key points are that physicians should focus on educating patients regarding: (1) when not to administer SLIT; (2) how to recognize a potentially serious allergic reaction to SLIT; and (3) when to administer epinephrine and seek emergency care.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 5, Issue 1, JanuaryâFebruary 2017, Pages 34-40.e2
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 5, Issue 1, JanuaryâFebruary 2017, Pages 34-40.e2
نویسندگان
Tolly G. MD, MS, Christopher MD, Linda S. MD, Sten MD,