Curcumin induces radiosensitivity of in vitro and in vivo cancer models by modulating pre-mRNA processing factor 4 (Prp4)

- Curcumin enhanced the sensitivity of cancer cells to radiation.
- Prp4K protects against IR-induced cell death.
- Prp4K over-expression activates anti-oxidant enzymes.
- Curcumin combined with IR prevents B16F10-induced tumor in C57BL/6J mice.