Studies on comparative efficacy of α-linolenic acid and α-eleostearic acid on prevention of organic mercury-induced oxidative stress in kidney and liver of rat

► This study establishes the effects of the dietary fats on MeHg+ mediated oxidative stress. ► A significant reduction in cellular antioxidative enzymes in liver and kidney due to MeHg+. ► MeHg+ administration altered lipid peroxidation, hepatic markers, protein synthesis. ► α-Linolenic and α-eleostearic acid individually acts against MeHg+. ► The ameliorative activity was best showed by high dose of (1.0%) α-linolenic acid.