Exercise affects memory acquisition, anxiety-like symptoms and activity of membrane-bound enzyme in brain of rats fed with different dietary fats: impairments of trans fat

▶We evaluated the impact of dietary trans fatty acids (FA) and exercise on behavior and Na+K+-ATPase activity. ▶Rats exercised and fed n-6/n-3 polyunsaturated FA showed lesser anxiety. ▶Exercise improved the memory acquisition impaired by dietary saturated and trans FA, which were incorporated in brain membranes. ▶Na+K+-ATPase activity was reduced in brain of rats fed trans and saturated FA, as well as by exercise.